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| 1 | Factors related to quality of life in patients with cirrhosis and ascites: Relevance of serum sodium concentration and leg edema显示文摘 | Elsa Solà Hugh Watson Isabel Graupera Fanny Turón Rogelio Barreto Ezequiel Rodríguez Marco Pavesi Vicente Arroyo Mónica Guevara Pere Ginès | 2012 | Journal of Hepatology2012，，6： | 3 |
| 2 | New standard in locally advanced rectal cancer显示文摘In the following review we intend to ascertain the optimal neoadjuvant therapy inpatients with locally advanced rectal cancer. In 2004, a study revealed thatchemoradiotherapy (CRT) resulted in better local control when performedpreoperatively rather than postoperatively, thus neoadjuvant treatment wasestablished as a standard treatment. Subsequently, the Polish study and the Trans-Tasman Radiation Oncology Group showed no statistically significant differencebetween concomitant CRT over 5 wk vs short-course radiotherapy (RT).Therefore, both were established as standard neoadjuvant treatments. Later, theStockholm III study demonstrated that short-course RT had a higher completepathological response than long-course RT. It also showed that a delay betweenRT and surgery presented fewer complications. This opened a window of time toprovide an early and effective systemic treatment to prevent distant metastases.Studies show that short-course RT plus oxaliplatin-based chemotherapy couldachieve this. When comparing this total neoadjuvant treatment (TNT) vsconcomitant CRT, the former showed greater complete pathological response andlower acute toxicity. Studies presented during 2020 have also shown the benefitsof TNT in terms of complete pathological response, as well as disease andmetastasis-free survival. Our review suggests that probably TNT should be thenew standard treatment for these patients. However, we will have to wait for thefull text publications of these studies to confirm this statement. | Sebastián Solé Ramón Baeza Carolina Gabler Felipe Couñago | 2020 | World Journal of Clinical Oncology2020，11，12： | 2 |
| 3 | Evaluation of hepatocellular carcinoma using SonoVue, a second generation ultrasound contrast agent: correlation with cellular differentiation显示文摘 | Carlos Nicolau Violeta Catalá Ramón Vilana Rosa Gilabert Luis Bianchi Manel Solé Mario Pagés Concepció Brú | 2004 | European Radiology2004，，6： | 2 |
| 4 | Variants at the promoter of the interleukin-6gene are associated with severity and outcome of pneumococcal community-acquired pneumonia显示文摘 | Ignacio Marítn-Loeches Jordi Solé-Violán Felipe Rodríguez de Castro | 2012 | Intensive Care Medicine2012，38，2： | 1 |
| 5 | Resistance to a drug blocking human immunodeficiency virus type 1 entry (RPR103611) is conferred by mutations in gp41 显示文摘 | Labrosse B Pleskoff O Sol N | 1997 | J Virol1997，71，： | 1 |
| 6 | Multiplexed Biosensing Diagnostic Platforms Detecting Autoantibodies to Tumor-Associated Antigens from Exosomes Released by CRC Cells and Tissue Samples Showed High Diagnostic Ability for Colorectal Cancer显示文摘Colorectal cancer(CRC)is the second leading cause of cancer-related death worldwide.The five-year survival rate of CRC patients depends on the stage at diagnosis,being higher than 80%when CRC is diagnosed in the early stages but lower than 10%when CRC is diagnosed in advanced stages.Autoantibodies against specific CRC autoantigens(tumor-associated antigens(TAAs))in the sera of patients have been widely demonstrated to aid in early diagnosis.Thus,we herein aim to identify autoantigens target of autoantibodies specific to CRC that possess a significant ability to discriminate between CRC patients and healthy individuals by means of liquid biopsy.To that end,we examined the protein content of the exosomes released by five CRC cell lines and tissue samples from CRC patients by means of immunoprecipitation coupled with mass spectrometry analysis.A total of 103 proteins were identified as potential autoantigens specific to CRC.After bioinformatics and meta-analysis,we selected 15 proteins that are more likely to be actual CRC autoantigens in order to evaluate their role in CRC prognosis by Western blot(WB)and immunohistochemistry(IHC).We found dysregulation at the protein level for 11 of these proteins in both tissue and plasma exosome samples from patients,along with an association of nine of these proteins with CRC prognosis.After validation,all but one showed a statistically significant high diagnostic ability to distinguish CRC patients and individuals with premalignant lesions from healthy individuals,either by luminescence Halotag-based beads,or by a multiplexed biosensing platform involving the use of magnetic microcarriers as solid support modified with covalently immobilized Halotag fusion proteins constructed for CRC detection.Taken together,our results highlight the usefulness of the approach defined here to identify the TAAs specific to chronic diseases;they also demonstrate that the measurement of autoantibody levels in plasma against the TAAs identified here could be integrated into a point-of-care(POC)device for CRC detection with high diagnostic ability. | Ana Montero-Calle Itziar Aranguren-Abeigon María Garranzo-Asensio Carmen Poves María Jesús Fernández-Aceñero Javier Martínez-Useros Rodrigo Sanz Jana Dziaková Javier Rodriguez-Cobos Guillermo Solís-Fernández Eloy Povedano Maria Gamella Rebeca Magnolia Torrente-Rodríguez Miren Alonso-Navarro Vivian de los Ríos J.Ignacio Casal Gemma Domínguez Ana Guzman-Aranguez Alberto Peláez-García JoséManuel Pingarrón Susana Campuzano Rodrigo Barderas | 2021 | Engineering2021，7，10： | 1 |
| 7 | Successful Treatment of Severe Gastrointestinal Bleeding Secondary to Crohn Disease with Recombinant Factor VIIa显示文摘 | Eva Girona Joaquín Borrás-Blasco Venancio Conesa-García Andrés Navarro-Ruiz Javier Solís Mariana Fe García-Sepulcre Israel Oliver-García | 2007 | Southern Medical Journal2007，，6： | 1 |
| 8 | Evaluation of hepatocellular carcinoma using SonoVue, a second generation ultrasound contrast agent: correlation with cellular differentiation显示文摘 | Carlos Nicolau Violeta Catalá Ramón Vilana Rosa Gilabert Luis Bianchi Manel Solé Mario Pagés Concepció Brú | 2004 | European Radiology2004，，6： | 1 |
| 9 | A randomized, controlled trial for risk factor reduction in patients with symptomatic vascular disease:the multidisciplinary Vascular Prevention by Nurses Study(VENUS)显示文摘 | Goessens BM ViSse1~n FL Sol BG | 2006 | Eur J Cardiovasc Prey Rehabil2006，13，： | 1 |
| 10 | Temporal and spatial patterns of soil moisture in semiarid badlands of SE Spain显示文摘 | Y. Cantón A. Solé-Benet F. Domingo | 2003 | Journal of Hydrology2003，，1： | 1 |
| 11 | Effect of sustained virological response to treatment on the incidence of abnormal glucose values in chronic hepatitis C显示文摘 | Manuel Romero-Gómez Conrado M. Fernández-Rodríguez Raúl J. Andrade Moisés Diago Sonia Alonso Ramón Planas Ricard Solá José A. Pons Javier Salmerón Rafael Barcena Ramón Perez Isabel Carmona Santiago Durán | 2008 | Journal of Hepatology2008，，5： | 1 |
| 12 | Topographic controls on the spatial distribution of ground cover in the Tabernas badlands of SE Spain显示文摘 | Y Cantón G Del Barrio A Solé-Benet R Lázaro | 2003 | Catena2003，，3： | 1 |
| 13 | Risk factors for pulmonary Aspergillus terreus infection in patients with positive culture for filamentous fungi显示文摘 | Castón JJ Linares MJ Gallego C Rivero A Font P Solís F | | 0，，： | 1 |
| 14 | Sieving crusts and macrofaunal activity control soil water repellency in semiaridenvironments:Evidences from SE Spain显示文摘 | Sergio Contreras Yolanda Cantón Albert Solé-Benet | 2008 | Geoderma2008，145，： | 1 |
| 15 | 法国立体定向脑电图指南显示文摘立体定向脑电图(SEEG)在上世纪60年代诞生于法国,由J.Talairach和J.Bancaud共同发明。SEEG为一种介入方法,可用于耐药性局灶癫痫,对癫痫放电在三维空间内进行实时记录,为'解剖-电关联分析'及精确外科切除提供客观依据。尽管这种方法被部分欧洲癫痫中心专家沿用长达数十年,然而,仅在近十年来才在世界范围内逐渐推广应用。在当代医疗实践中,SEEG不仅为诊断方法,也被用于治疗,如射频热凝治疗等。为达到临床上更加合理应用SEEG的目的,我们认为需要有正式指南,为此成立了特别工作组,由全法国各地大型癫痫中心(过去连续5年中每年完成SEEG超过10例)专家组成。先由工作组会议形成初步建议,然后由全体专家依据已有方法学对其进行评分。指南第一部分包括下列主题内形成框架建议:SEEG适应证与局限性;SEEG计划与实施;外科技术;电生理操作技术;SEEG解读;SEEG引导下射频热凝。指南的第二部分,由各个专家小组基于现有文献以及他们个人经验对这些议题的具体内容进一步详述。这项工作旨在向应用SEEG的癫痫中心提供了解法国专家共识的机会,尤其是那些正处在起步阶段的癫痫中心,可以作为参考蓝本。该指南的编写得到法国临床神经生理学会、国际抗癫痫联盟法国分支机构的支持。 | Isnard J Taussig D Bartolomei F Bourdillon P Catenoix H Chassoux F Chipaux M Clémenceau S Colnat-Coulbois S Denuelle M Derrey S Devaux B Dorfmüller G Gilard V Guenot M Job-Chapron AS LandréE Lebas A Maillard L McGonigal A Minotti L Montavont A Navarro V Nica A Reyns N Scholly J Sol JC Szurhaj W Trebuchon A Tyvaert L Valenti-Hirsch MP Valton L Vignal JP Sauleau P 龙绮婷 张翠荣 尚力 张玮 刘兴洲 | 2018 | 癫痫杂志2018，4，4： | 1 |
| 16 | Chronic intestinal pseudo-obstruction:a diagnosis to be considered显示文摘 | Munoz-Yagüe MT Solís-Mu(n)oz P Salces I | | 0，，05： | 1 |
| 17 | 439 I148M PNPLA3 VARIANT PROMOTES STEATOSIS ACCORDING TO VIRAL AND IL28B GENOTYPE BUT DOES NOT AFFECT SUSTAINED VIRAL RESPONSE IN PATIENTS WITH HEPATITIS C显示文摘 | J. Ampuero L. Rojas R. Calle L. Ortíz-Fernández J.R. García- Lozano R. Solá X. Forns R. Andrade M. Diago J.A. Pons J.M. Navarro R. Millán M. González-Escribano M. Romero- Gómez | 2013 | Journal of Hepatology2013，，： | 1 |
| 18 | Severe acute kidney injury associated with non-steroidal anti-inflammatory drugs in cirrhosis: A case-control study显示文摘 | Chiara Elia Isabel Graupera Rogelio Barreto Elsa Solà Rebeca Moreira Patricia Huelin Xavier Ariza Cristina Solé Elisa Pose Anna Baiges Núria Fabrellas Esteban Poch Javier Fernández Vicente Arroyo Pere Ginès | 2015 | Journal of Hepatology2015，，3： | 1 |
| 19 | Possible interactions between the NS-1 protein and tumor necrosis factor alpha pathways in erythroid cell apoptosis induced by human parvovirus B19显示文摘 | Sol N Le JJ Vassias I | 1999 | J Virol1999，73，10： | 1 |
| 20 | Pressure- induced action polymerization in vasclar smooth muscle as a mechanism underiying nyogenic behavior显示文摘 | Gipolla M J Gokina N I ()sol G | 2002 | FASEB J2002，16，1： | 1 |
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