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| 1 | Triglyceride levels and apolipoprotein E polymorphism in patients with acute pancreatitis显示文摘BACKGROUND:Hypertriglyceridemia is an unusual cause of acute pancreatitis and sometimes considered to be an epiphenomenon.This study aimed to investigate the clinical and analytical features and the APOE genotypes in patients with acute pancreatitis and severe hypertriglyceridemia.METHODS:We undertook a one-year,prospective study of patients with acute pancreatitis whose first laboratory analysis on admission to the emergency department included measurement of serum triglycerides.The APOE genotype was determined and the patients answered an established questionnaire within the first 24 hours concerning their alcohol consumption,the presence of co-morbidities and any medications being taken.The patients' progression,etiological diagnosis,hospital stay and clinical and radiological severity were all recorded.RESULTS:Hypertriglyceridemia was responsible for 7 of 133 cases of pancreatitis (5%);the remaining cases were of biliary (53%),idiopathic (26%),alcoholic (11%) or other (5%) origin.Compared with these remaining cases,the patients with hypertriglyceridemia were significantly younger,had more relapses,and more often had diabetes mellitus.They usually consumed alcohol or consumed it excessively on the days before admission.Also,the ε4 allele of the APOE gene was more common in this group (P<0.05).CONCLUSION:One of 20 episodes of acute pancreatitis is caused by hypertriglyceridemia and it is linked to genetic (ε4 allele) and comorbid factors such as diabetes and,especially,alcohol consumption. | Radka Ivanova Susana Puerta Alfonso Garrido Ignacio Cueto Ana Ferro María José Ariza Andrés Cobos Pedro González-Santos Pedro Valdivielso | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，1： | 26 |
| 2 | Risk factors for resistance to ceftriaxone and its impact on mortality in community, healthcare and nosocomial spontaneous bacterial peritonitis显示文摘 | Xavier Ariza José Castellote Jaime Lora-Tamayo Anna Girbau Sílvia Salord Rosa Rota Javier Ariza Xavier Xiol | 2011 | Journal of Hepatology2011，，4： | 5 |
| 3 | Serious drug-induced liver disease secondary to ezetimibe显示文摘Ezetimibe is the f irst member of a new family of lipid- lowering drugs that inhibits uptake of dietary and bili- ary cholesterol. It was approved by the FDA in 2002 for hypercholesterolemia alone or in combination with statins. Its use has been spreading over the last years. Ezetimibe was considered a safe drug. We report a case of a woman who developed a serious hepatocellular drug-induced liver disease after 4 mo therapy with 10 mg daily of ezetimibe. After withdrawal of the drug, the patient recovered slowly. Ezetimibe may produce seri- ous toxic hepatitis and prompt withdrawal is mandatory in case of a signif icant abnormality in liver testing after beginning or during treatment with ezetimibe. | José Castellote Javier Ariza Rosa Rota Anna Girbau Xavier Xiol | 2008 | World Journal of Gastroenterology2008，14，32： | 3 |
| 4 | Collision-induced dissociation of cytidine and its derivatives 显示文摘 | JENSEN S S ARIZA X NIELSEN P | 2007 | J Mass Spectrom2007，42，1： | 1 |
| 5 | Mathematical Morphology Applied to Raster Generalization of Urban City Block Maps 显示文摘 | Manuel Antonio Urena Camara Francisco Javier Ariza Lopez | 2000 | Cartographica2000，37，1： | 1 |
| 6 | p53 Immunoreactivity in hepatoeellular adenoma focal nodular hyperplasia cirrhosis and hepatocellular carcinoma显示文摘 | A Ariza E M Castella | 1995 | Histopathology1995，26，： | 1 |
| 7 | Afamily with a milder formofadultdominant polycystic kidney disease not linked to the PKD1 (16p) orPKD2(4q) genes显示文摘 | ALVAREZ V MARIN R | 1997 | J Med Genet1997，34，4： | 1 |
| 8 | Clinical relevance of Acinetobacter baumannii ventilator-associated pneumonia显示文摘 | Montero A Corbella X Ariza J | 2003 | Crit Care Med2003，31，： | 1 |
| 9 | Comparison of biota sample pretreatments for arsenic speciation with coupled HPLC-HG-ICP-MS显示文摘 | ARIZA J L G RODAS D S GIRALDEZ I | 2000 | Analyst2000，125，： | 1 |
| 10 | Spatial variations of heavy metals contamination in sediments from Odiel river(Southwest Spain)显示文摘 | BERMEJO J C S BELTRAN R ARIZA J L | 2003 | Environment International2003，29，： | 1 |
| 11 | Percutaneous treatment of superior vena cava syndrome using metallic stents显示文摘 | DE GREGORIO ARIZA MA GAMBOA P GIMENO MJ | 2003 | Eur Radiol2003，13，： | 1 |
| 12 | Safety and efficacy of moxifl oxacin vs levofl oxacin in the treatment of AECB显示文摘 | Urueta J Ariza J De Brito A | 2001 | Clin Microbiol Infect2001，7，1： | 1 |
| 13 | Gastrointestinal autonomic nerve tumor: further observation regarding an ultrastructural and immunohistochemical analysis of six cases显示文摘 | Ojanguren I Ariza A Navas-Polacios JJ | 1996 | Hum Pathol1996，27，： | 1 |
| 14 | Restoration SPOT images using PSF-drived deconvolution filters 显示文摘 | Ruiz C P Ariza Lopez F J | 2002 | International Journal of Remote Sensing2002，23，12： | 1 |
| 15 | Analysis of factors influen- cing pregnancy rates in homologous intrauterine insemination 显示文摘 | Iberico G Vioque J Ariza N | 2004 | Fertil Steril2004，81，5： | 1 |
| 16 | Spatial variations of heavy metals contamination in sediments from Odiel river(Southwest Spain)显示文摘 | Santos Bermejo J C Beltrán R Gómez Ariza J L | 2003 | Environment International2003，29，1： | 1 |
| 17 | Spatial variations of heavy metals contamination in sediments from Odiel river(Southwest Spain)显示文摘 | BERMEJO J C S BELTRáN R ARIZA J L | 2003 | Environment International2003，29，： | 1 |
| 18 | A family with a milder form of adult dominant polycystic kidney disease not linked to the PKDI(16p)or PKD2(4q)genes显示文摘 | Ariza M Alvarez V Marin R | 1997 | J Med Genet1997，34，： | 1 |
| 19 | Assessment of Acinetobact- er baumannii susceptibility to antiseptics and disinfectants 显示文摘 | Martro E Hernandez A Ariza J | 2003 | J Hosp Infect2003，55，1： | 1 |
| 20 | Rapid determination of glutathione status in fish liver using high-performance liquid chromatography and electrochemical dedection 显示文摘 | Ariza AR Toribio F Barea JL | 1994 | Journal of Chromatography B1994，656，： | 1 |
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