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| 1 | How to assess the efficacy or failure of targeted therapy:deciding when to stop sorafenib in hepatocellular carcinoma显示文摘Sorafenib is thus far the only systemic treatment for hepatocellular carcinoma(HCC) based on the results of two randomized controlled trials performed in Western and in Eastern countries, despite a poor response rate(from 2% to 3.3%) following conventional evaluation criteria. It is now recognized that the criteria(European Association of the Study of the Liver criteria, modified response evaluation criteria in solid tumors) based on contrast enhanced techniques(computed tomography scan, magnetic resonance imaging) aimed to assess the evolution of the viable part of the tumor(hypervascularized on arterial phase) are of major interest to determine the efficacy of sorafenib and of most antiangiogenic drugs in patients with HCC. The role of alphafetoprotein serum levels remains unclear. In 2016, in accordance with the SHARP and the Asia-Pacific trials, sorafenib must be stopped when tolerance is poor despite dose adaptation or in cases of radiological and symptomatic progression. This approach will be different in cases of available second-line therapy trials. Some recent data(in renal cell carcinoma) revealed that despite progression in patients who received sorafenib, this drug can still decrease tumor progression compared to drug cessation. Then, before deciding to continue sorafenib post-progression or shift to another drug, knowing other parameters of post-progression survival(Child-Pugh class, Barcelona Clinic Liver Cancer, alphafetoprotein, post-progression patterns in particular, the development of extrahepatic metastases and of portal vein thrombosis) will be of major importance. | Jean-Luc Raoul Xavier Adhoute Marine Gilabert Julien Edeline | 2016 | World Journal of Hepatology2016，8，35： | 8 |
| 2 | ARFI, FibroScan?, ELF, and their combinations in the assessment of liver fibrosis: A prospective study显示文摘 | Gonzalo Crespo Guillermo Fernández-Varo Zoe Mari?o Gregori Casals Rosa Miquel Stella M. Martínez Rosa Gilabert Xavier Forns Wladimiro Jiménez Miquel Navasa | 2012 | Journal of Hepatology2012，，2： | 3 |
| 3 | Renal Failure in Patients With Cirrhosis and Sepsis Unrelated to Spontaneous Bacterial Peritonitis: Value of MELD Score显示文摘 | Carlos Terra Mónica Guevara Aldo Torre Rosa Gilabert Javier Fernández Marta Martín-Llahí Maria E. Baccaro Miquel Navasa Conxita Bru Vicente Arroyo Juan Rodés Pere Ginès | 2005 | Gastroenterology2005，，6： | 2 |
| 4 | Evaluation of hepatocellular carcinoma using SonoVue, a second generation ultrasound contrast agent: correlation with cellular differentiation显示文摘 | Carlos Nicolau Violeta Catalá Ramón Vilana Rosa Gilabert Luis Bianchi Manel Solé Mario Pagés Concepció Brú | 2004 | European Radiology2004，，6： | 2 |
| 5 | Ultrasonographic evaluation of liver surface and transient elastography in clinically doubtful cirrhosis显示文摘 | Annalisa Berzigotti Juan G. Abraldes Puneeta Tandon Eva Erice Rosa Gilabert Juan Carlos García-Pagan Jaime Bosch | 2010 | Journal of Hepatology2010，，6： | 2 |
| 6 | Chemical etching of CdZnTe(111)suffaces 显示文摘 | Trigubo A B | 1994 | Materials Science and Engineering1994，27，： | 1 |
| 7 | An Atmospheric Correction Method for the Automatic Retrieval of Surface Reflectance from TM Images显示文摘 | GILABERT M A CONESE C MASELL F | 1994 | INTJ Remote Sensing1994，15，10： | 1 |
| 8 | The effect of estrogen replacement therapy with or without progestogen on the fibrinolytic system and coagulation inhibitors in postmenopausal status显示文摘 | Gilabert J Estelles A Cano A | 1995 | Am J Obstet Gynecol1995，173，6： | 1 |
| 9 | Analyses of spectral-biophysical relationships for a eom canopy显示文摘 | Gilabert M A Gandia S Melit J | 1996 | Remote Sensing of Environment1996，55，1： | 1 |
| 10 | Early detection of hepatic artery thrombosis after liver transplantation by Doppler ultrasonography: prognostic implication显示文摘 | Garcia-Criado A Gilabert R Nicolau C | 2001 | J Ultrasound Med2001，20，1： | 1 |
| 11 | Arachnoid cysts of the middle cranial fossa:a consideration of their origion based on imaging显示文摘 | García samtps JM Martímez-lage J GILABERT UBEDA A | 1993 | Neuroradiology1993，35，5： | 1 |
| 12 | Bullous pemphigoid in a patient with psoriasis during the course of PUVA therapy: Study by ELISA test 显示文摘 | Bamadas MA Gilaberte M Pujol R | 2006 | Int J Dennatol2006，45，9： | 1 |
| 13 | Expression of several components of the plasminogen activator and matrix metalloproteinase in endometriosis显示文摘 | Gilabert-Estelles J Estella A Gilabert J | 2003 | Hum Repord2003，18，7： | 1 |
| 14 | Linear spectral mixture modeling to estimate vegetation amount from optical spectral data显示文摘 | GARCIA-HARO F J GILABERT M A MELIA J | 1996 | International Journal of Remote Sensing1996，17，： | 1 |
| 15 | Noninvasive prediction of clinically significant portal hypertension and esophageal varices in patients with compensated liver cirrhosis显示文摘 | Berzigotti A Gilabert R Abraldes JG | 2008 | Am J Gastroenterol2008，103，5： | 1 |
| 16 | Laparoscopic distal pancreatectomy combined with preservation of the spleen for cystic neo- plasms of the pancreas显示文摘 | Fernandez-Cruz L Mart nez I Gilabert R | 2004 | J Gastrointest Surg2004，8，4： | 1 |
| 17 | A generalized soil-adjusted vegetation index显示文摘 | Gilabert M A Gonzalez-Piqueras J Garcia-Haro F J | 2002 | Remote Sensing of Environment2002，82，： | 1 |
| 18 | Antioxidant intracellur activity of geistein and equol显示文摘 | PEREBOOM D GILABERTE Y SINUES B | 1999 | Medicinal Food1999，2，34： | 1 |
| 19 | TIPS is a useful longterm derivative therapy for patients with Budd chiarisyndrome uncontrolled by medicaitherapy显示文摘 | Perello A Garcia-Pagan JC Gilabert R | 2002 | Hepatology2002，35，5： | 1 |
| 20 | Integration of High and Low Resolution NDVI Data for Monitoring Vegetation in Mediterranean Environments 显示文摘 | Fabio M Gilabert M A Conese C | 1998 | Remote Sensing of Environment1998，63，： | 1 |
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