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| 1 | Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density显示文摘 | W.S Simonet D.L Lacey C.R Dunstan M Kelley M.-S Chang R Lüthy H.Q Nguyen S Wooden L Bennett T Boone G Shimamoto M DeRose R Elliott A Colombero H.-L Tan G Trail J Sullivan E Davy N Bucay L Renshaw-Gegg T.M Hughes D Hill W Pattison P Campbell S Sander G Van | 1997 | Cell1997，，2： | 6 |
| 2 | Targeting head and neck tumoral stem cells: From biologicalaspects to therapeutic perspectives显示文摘Head and neck squamous cell cancer(HNSCC) is the sixth most common cancer in the world. Effective therapeutic modalities such as surgery, radiation, chemotherapy and combinations of each are used in the management of the disease. In most cases, treatment fails to obtain total cancer cure. In recent years, it appears that one of the key determinants of treatment failure may be the presence of cancer stem cells(CSCs) that escape currently available therapies. CSCs form a small portion of the total tumor burden but may play a disproportionately important role in determining outcomes. CSCs have stem features such as self-renewal, high migration capacity, drug resistance, high proliferation abilities. A large body of evidence points to the fact that CSCs are particularly resistant to radiotherapy and chemotherapy. In HNSCC, CSCs have been increasingly shown to have an integral role in tumor initiation, disease progression, metastasis and treatment resistance. In the light of such observations, the present review summarizes biological characteristics of CSCs in HNSCC, outlines targeted strategies for the successful eradication of CSCs in HNSCC including targeting the self-renewal controlling pathways, blocking epithelial mesenchymal transition, niche targeting, immunotherapy approaches and highlights the need to better understand CSCs biology for new treatments modalities. | Benoîte Méry Jean-Baptiste Guy Sophie Espenel Anne-Sophie Wozny Stéphanie Simonet Alexis Vallard Gersende Alphonse Dominique Ardail Claire Rodriguez-Lafrasse Nicolas Magné | 2016 | World Journal of Stem Cells2016，8，1： | 3 |
| 3 | Rapid fluores- cence determination of diquat herbicide in food grains using quan- tum dots as new reducing agent 显示文摘 | Carrillo-Carri6n C Simonet B M Valctrcel M | 2011 | Anal Chim Acta2011，692，12： | 1 |
| 4 | In situ synthesis of magnetic multiwalled carbon nanotube composites for the clean - up of ( fluoro ) quinolones from human plasma prior to ultrahigh pressure liquid chromatography analysis 显示文摘 | Morales -Cid G Fekete A Simonet B M | 2010 | Anal Chem2010，82，： | 1 |
| 5 | Frankia Genus-Specific Characterization by Polymerase Chain Reaction显示文摘 | SIMONET P GROSJEAN M C MISRA A K | 1991 | Appl Environ Microbiol1991，57，11： | 1 |
| 6 | Bioactivepolar triterpenoids from Melilotus messanensis显示文摘 | Macias F A Simonet A M Galindo J C G er al | 1998 | Phytochemistry1998，49，3： | 1 |
| 7 | Economic impact of preoperative intraaortic balloon pump therapy in high-risk coronary patients 显示文摘 | Christenson JT Simonet F Schmuziger M | 2000 | Ann Thorac Surg2000，70，： | 1 |
| 8 | Cosegregation of the rennin allele of the spontaneously hypertensive rat with an increase in blood pressure显示文摘 | KURTZ T W SIMONET L KABRA P M | 1990 | J Clin Invest1990，85，4： | 1 |
| 9 | Bioactivephenolics and polar compounds from Melilotusmessanensis显示文摘 | Macias F A Simonet A M Galindo J CG | 1999 | Phytochemistryf1999，50，1： | 1 |
| 10 | The effect of preoperative intra-aortic balloon pump support in high risk patients requiring myocardial revascularization显示文摘 | Christenson JT Simonet F Schmuziger M | 1997 | J Cardiovasc Surg(Torino)1997，38，4： | 1 |
| 11 | Effective surgical management of high-risk coronary patients using preoperative intra-aortic balloon counterpulsation therapy 显示文摘 | Christenson JT Schmuziger M Simonet F | 2001 | Cardiovasc Surg2001，9，4： | 1 |
| 12 | Economic im-pact of preoperative intraaortic balloon pump therapy in high-risk coronary patients显示文摘 | Christenson JT Simonet F Schmuziger M | 2000 | Ann Thorac Surg2000，70，2： | 1 |
| 13 | Kinetic-turbidimetric determination of phytic acid by sequential injection analysis显示文摘 | J G March B M Simonet F Grases | 2000 | Analytica chimica acta2000，409，12： | 1 |
| 14 | The effects of ozone on the nucleus pulposus:pathological data on one surgical specimen显示文摘 | Leonardi M Simonet ti L Barbara C | 2001 | Riv Neuroradiol2001，14，1： | 1 |
| 15 | Polyester urethane foam scaffold for smooth muscle cell tissue engineering显示文摘 | Danielsson C Ruault S Simonet M | 2006 | Biomaterials2006，27，8： | 1 |
| 16 | The effect of preoperative support in high risk patients requiring myocardial revascularization 显示文摘 | CHRISTENSON JT SIMONET F SCHMUZIGER M | 2006 | J Cardiovasc Surg2006，38，： | 1 |
| 17 | U1- traporous 3d polymer meshes by low-temperature electro- spinning: Use of ice crystals as a removable void template 显示文摘 | Simonet M Schneider O D Neuenschwander P | 2007 | Polym Eng Sci2007，47，12： | 1 |
| 18 | Effects of exogenous inositol hexakisphophate(InsP6)on the levels of InsP6 and inositol trisphophate(InsP3)in malignant cells,tissues and biological fluids显示文摘 | Felix Grases Bartolome M Simonet | 2002 | Life Science2002，71，： | 1 |
| 19 | Determination of residual chlorine in greywater using o-tolidine显示文摘 | MARCH J G GUAL M SIMONET B M | 2002 | Talanta2002，58，： | 1 |
| 20 | 显示文摘 | SUAREZ B SIMONET B M CARDENAS S | 2007 | Electrophoresis2007，28，11： | 1 |
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