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| 1 | A novel preparation of nanosized hexagonal Mg(OH)2 as a flame retardant显示文摘 | Yongbin Chen Tao Zhou Huaxiong Fang Simin Li Yuting Yao Bailin Fan Jian Wang | 2016 | Particuology2016，14，1： | 10 |
| 2 | Controlled preparation and characterization of nano-sized hexagonal Mg(OH)_2 flame retardant显示文摘Nano-sized hexagonal magnesium hydroxide(Mg(OH)_2) with good dispersibility was synthesized by a double injection-hydrothermal method,utilizing polyvinylpyrrolidone(PVP) as an additive and with optimized processing parameters.SEM and BET analysis showed that the mean particle size and specific surface area of the Mg(OH)_2 particles were 174 nm and 50.77 m^2/g,respectively.The FT-IR spectra and the XRD patterns showed that PVP was adsorbed on the surface of the Mg(OH)_2 crystal,thus effectively limiting particle agglomeration and hindering crystal growth along the(101) plane.TGA showed a decrease in the decomposition temperature and an increase in the weight loss of the Mg(OH)_2 particles due to addition of PVP. | Huaxiong Fang Tao Zhou Xiangping Chen Simin Li Guangshan Shen Xiaoyan Liao | 2014 | Particuology2014，12，3： | 10 |
| 3 | Focal adhesion protein Kindlin-2 regulates bone homeostasis in mice显示文摘Our recent studies demonstrate that the focal adhesion protein Kindlin-2 is critical for chondrogenesis and early skeletal development. Here, we show that deleting Kindlin-2 from osteoblasts using the 2.3-kb mouse Col1 a1-Cre transgene minimally impacts bone mass in mice, but deleting Kindlin-2 using the 10-kb mouse Dmp1-Cre transgene, which targets osteocytes and mature osteoblasts, results in striking osteopenia in mice. Kindlin-2 loss reduces the osteoblastic population but increases the osteoclastic and adipocytic populations in the bone microenvironment. Kindlin-2 loss upregulates sclerostin in osteocytes,downregulates β-catenin in osteoblasts, and inhibits osteoblast formation and differentiation in vitro and in vivo. Upregulation ofβ-catenin in the mutant cells reverses the osteopenia induced by Kindlin-2 deficiency. Kindlin-2 loss additionally increases the expression of RANKL in osteocytes and increases osteoclast formation and bone resorption. Kindlin-2 deletion in osteocytes promotes osteoclast formation in osteocyte/bone marrow monocyte cocultures, which is significantly blocked by an anti-RANKLneutralizing antibody. Finally, Kindlin-2 loss increases osteocyte apoptosis and impairs osteocyte spreading and dendrite formation.Thus, we demonstrate an important role of Kindlin-2 in the regulation of bone homeostasis and provide a potential target for the treatment of metabolic bone diseases. | Huiling Cao Qinnan Yan Dong Wang Yumei Lai Bo Zhou Qi Zhang Wenfei Jin Simin Lin Yiming Lei Liting Ma Yuxi Guo Yishu Wang Yilin Wang Xiaochun Bai Chuanju Liu Jian QFeng Chuanyue Wu Di Chen Xu Cao Guozhi Xiao | 2020 | Bone Research2020，8，1： | 8 |
| 4 | Numerical study of three phase shifts and dual corrugation pitch modulated(CPM) DFB semiconductor lasers based on reconstruction equivalent chirp technology显示文摘A distributed feedback(DFB) semiconductor laser with three phase shifts based on reconstruction equivalent chirp(REC) technology is proposed and investigated numerically.With the combination of multiple phase shifts and corrugation pitch modulated(CPM) structure,we also propose a novel and more complex structure named dual CPM,which has a flatter light power distribution along the laser cavity compared with the true double phase shifts DFB laser diode(LD),while the P-I curves are nearly the same.The proposed dual CPM structure is also designed and analyzed based on REC technology.The simulation results show that,the DFB semiconductor laser with complex structure such as phase shifts,or even arbitrary variation of the grating period can be achieved equivalently and easily by changing the sampling structure.But its external characteristics are almost the same as those DFB lasers with true phase shifts,or true arbitrary variation of the grating period.The key advantage of the REC technology is that it varies only the sampling structure and keeps the seed grating(actual grating in sampling structure) period constant.So its fabrication needs only low-cost and standard holographic exposure technology.Therefore we believe this method can achieve the high-end and low-cost DFB LD for mass production. | SHI YueChun TU XingHua LI SiMin ZHOU YaTing JIA LingHui CHEN XiangFei | 2010 | Chinese Science Bulletin2010，55，35： | 4 |
| 5 | Experimental demonstration of the three-phase-shifted DFB semiconductor laser with buried heterostructure using common holographic exposure显示文摘In this article,we report the first experimental demonstration of the three-phase-shifted(3PS)DFB semiconductor laser with buried heterostructure based on the Reconstruction-Equivalent-Chirp(REC)technique.The simulation results show that the performances of the equivalent 3PS DFB semiconductor laser are nearly the same as those of the true 3PS laser.Compared with the quarter-wave-phase shift(QWS)DFB semiconductor laser,the 3PS DFB semiconductor laser shows better single-longitude-mode(SLM)property even at high injection current with high temperature.However,it only changes theμm-level sampling structures but the seed grating is uniform using the REC technique.Therefore,its fabrication cost is low. | LU LinLin CAO BaoLi ZHANG LiBo TANG Song LI LianYan LI SiMin SHI YueChun CHEN XiangFei | 2014 | Science China(Technological Sciences)2014，57，11： | 4 |
| 6 | Tectonics-palaeogeomorphology in rift basins: controlling effect on the sequence architecture显示文摘The relationship between deposition and tectonics of sedimentary basins has been a significant subject in recent years.Using typical rift basins such as the Nanpu Sag as an example,combined with the analysis of the tectonics-palaeogeomorphology of basins,we undertook a detailed study of the differences of the third-order sequences in different basins,the combination of depositional systems within the sequence framework and the distribution of depocenters and subsidence centers.Our results revealed a significant relationship between the tectonics-palaeogeomorphology of rift basins and the filling styles of sedimentary sequences.The basin structure plays a primary role in controlling the development of the third-order sequences and the boundary of these sequences is easily formed in basins with gentle slopes,shallow water and a small area.The characteristics of the tectonics-palaeogeomorphology of rift basins are dominated by half-grabens of extensional faults,which affect the temporal and spatial combination of sedimentary systems within the sequences as well as the distribution of depocenters and subsidence centers.Based on the development rules of the faults dominating the half-grabens of extensional faults,rift basins are classified into two types: the single fault segmented-linkage type and the multi-fault combination type.The main controlling factors of the temporal and spatial combination of sedimentary systems and the distribution of depocenters and subsidence centers in different basins are different.The characteristics of early segmentation and later linkage of the faults play a critical role in controlling the sedimentary system combination within the sequence framework and the temporal and spatial differences of depocenters and subsidence centers of the single fault segmented-linkage rift basins,while the differences in fault activities are the dominating factors of the multi-fault combination rift basins. | Ji Hancheng Jia Haibo Sun Simin Chen Liang Tang Yang Chen Wei Geng Yikai Zhou Hang | 2013 | Petroleum Science2013，10，4： | 3 |
| 7 | Dielectric Properties of Bi_4Ti_3O_(12) Ceramics by Impedance Spectroscopic Method显示文摘Various lead-free ceramics have been investigated in search for new high-temperature dielectrics. In particular, Bi_4Ti_3O_(12) is a type of ferroelectric ceramics, which is supposed to replace leadcontaining ceramics for its outstanding dielectric properties in the near future. Ferroelectric ceramics of Bi_4Ti_3O_(12) made by conventional mixed oxide route have been studied by impedance spectroscopy in a wide range of temperature. X-ray diffraction patterns show that Bi_4Ti_3O_(12) ceramics are a single-phase of ferroelectric Bi-layered perovskite structure whether it is calcined at 800 ℃ or after sintering production. This study focused on the effect of the grain size on the electric properties of BIT ceramics. The BIT ceramics with different grain sizes were prepared at different sintering temperatures. Grain becomes coarser with the sintering temperature increasing by 50 ℃, relative permittivity and dielectric loss also change a lot. When sintered at 1 100 ℃, r values peak can reach 205.40 at a frequency of 100 k Hz, the minimum dielectric losses of four different frequencies make no difference, all close to 0.027. The values of Ea range from 0.52 to 0.68 e V. The dielectric properties of the sample sintered at 1 100 ℃ are relatively better than those of the other samples by analyzing the relationship of the grain, the internal stresses, the homogeneity and the dielectric properties. SEM can better explain the results of the dielectric spectrum at different sintering temperatures. The results show that Bi_4Ti_3O_(12) ceramics are a kind of dielectrics. Thus, Bi_4Ti_3O_(12) can be used in high-temperature capacitors and microwave ceramics. | 陈勇 SU Huyin XUE Simin LI Zhaozhi ZHANG Cancan CHEN Qi XU Lingfang 曹万强 黄兆祥 | 2016 | Journal of Wuhan University of Technology(Materials Science)2016，31，5： | 3 |
| 8 | Effects of characteristic inhomogeneity of bamboo culm nodes on mechanical properties of bamboo fiber reinforced composite显示文摘Dendrocalamus farinosus and Phyllostachys heterocycla bamboo logs were subjected to a novel treatment process for the preparation of bamboo fiber mats(BFMs), and the obtained BFM were used to fabricate bamboo fiber reinforced composite(BFRC). We studied the mechanical properties of the BFRCs manufactured from the mats with and without bamboo nodes. The presence of nodes in BFM greatly reduced tensile strength,compressive strength, modulus of elasticity, and modulus of rupture of the BFRCs, while the BFRCs fabricated from BFMs with nodes possessed higher horizontal shear strength. Therefore, the nodes in bamboo culms were an important factor in the uniform distribution of mechanical properties, and BFMs should be homogeneously arranged to reduce the impact of nodes on the mechanical strengths of BFRCs. | Jinqiu Qi Jiulong Xie Wenji Yu Simin Chen | 2015 | Journal of Forestry Research2015，26，4： | 3 |
| 9 | The interaction between polyphyllin I and SQLE protein induces hepatotoxicity through SREBP-2/HMGCR/SQLE/LSS pathway显示文摘Polyphyllin I(PPI)and polyphyllin II(PII)are the main active substances in the Paris polyphylla.However,liver toxicity of these compounds has impeded their clinical application and the potential hepatotoxicity mechanisms remain to be elucidated.In this work,we found that PPI and PII exposure could induce significant hepatotoxicity in human liver cell line L-02 and zebrafish in a dose-dependent manner.The results of the proteomic analysis in L-02 cells and transcriptome in zebrafish indicated that the hepatotoxicity of PPI and PII was associated with the cholesterol biosynthetic pathway disorders,which were alleviated by the cholesterol biosynthesis inhibitor lovastatin.Additionally,3-hydroxy-3-methy-lglutaryl CoA reductase(HMGCR)and squalene epoxidase(SQLE),the two rate-limiting enzymes in the cholesterol synthesis,selected as the potential targets,were confirmed by the molecular docking,the overexpression,and knockdown of HMGCR or SQLE with siRNA.Finally,the pull-down and surface plasmon resonance technology revealed that PPI could directly bind with SQLE but not with HMGCR.Collectively,these data demonstrated that PPI-induced hepatotoxicity resulted from the direct binding with SQLE protein and impaired the sterol-regulatory element binding protein 2/HMGCR/SQLE/lanosterol synthase pathways,thus disturbing the cholesterol biosynthesis pathway.The findings of this research can contribute to a better understanding of the key role of SQLE as a potential target in drug-induced hepatotoxicity and provide a therapeutic strategy for the prevention of drug toxic effects with similar structures in the future. | Zhiqi Li Qiqi Fan Meilin Chen Ying Dong Farong Li Mingshuang Wang Yulin Gu Simin Guo Xianwen Ye Jiarui Wu Shengyun Dai Ruichao Lin Chongjun Zhao | 2023 | Journal of Pharmaceutical Analysis2023，13，1： | 2 |
| 10 | Experimental demonstration of λ/8 DFB semiconductor laser array for 1.3 μm CWDM system显示文摘In this article,we report the first experimental demonstration of an eight-wavelength λ/8 phased-shifted laser array based on the REC technique in the 1.3 μm wavelength domain.Measurement results exhibit good linearity of lasing wavelength with+/-0.35 nm wavelength residual.The SLM property was ensured with SMSRs all larger than 38 dB.Moreover,the directmodulation performance was also tested.The experimental results show that the modulation bandwidth can reach up to 13GHz even at the small injection current of 40 mA and the measured spurious-free dynamic range(SFDR)is up to 87 dB/Hz2/3,which shows good linearity.These measurements show that REC-based λ/8 phased-shifted laser array has good modulation performance and it may find potential application in actual fiber-optic systems. | LU LinLin HUANG Long SHI YueChun GUO RenJia LIU Rui LI LianYan LI SiMin CHEN XiangFei | 2014 | Science China(Technological Sciences)2014，57，9： | 2 |
| 11 | Temperature Effect in (K_(0.5)Na_(0.5))_(0.2)(Sr_(0.75)Ba_(0.25))_(0.9)Nb_(2)0_(6): Cu Crystal Self-Pumped Phase-Conjugator显示文摘A reflectivity of 45%of the self-pumped phase-conjugate wave in (K_(0.5)Na_(0.5))_(0.2)(Sr_(0.75)Ba_(0.25))_(0.9)Nb_(2)0_(6)-Cn crystal at the environmental temperature T~70℃ has been obtained.The temperature effect in this kind of self-pumped phase-conjugator is studied. | XU Jingjun LIU Simin WU Yuanqing ZHANG Guangyin SUN Daliang SONG Yongyuan CHEN Huanchu | 1992 | Chinese Physics Letters1992，9，7： | 1 |
| 12 | Topological electronic states in HfRuP family superconductors显示文摘Based on the first-principles calculations and experimental measurements,we report that the hexagonal phase of ternary transition metal pnictides TT’X(T=Zr,Hf;T’=Ru;X=P,As),which are well-known noncentrosymmetric superconductors with relatively high transition temperatures,host nontrivial bulk topology.Before the superconducting phase transition,we find that HfRuP belongs to a Weyl semimetal phase with 12 pairs of type-II Weyl points,while ZrRuAs,ZrRuP and HfRuAs belong to a topological crystalline insulating phase with trivial Fu-Kane Z_(2) indices but nontrivial mirror Chern numbers.High-quality single crystal samples of the noncentrosymmetric superconductors with these two different topological states have been obtained and the superconductivity is verified experimentally.The wide-range band structures of ZrRuAs have been identified by ARPES and reproduced by theoretical calculations.Combined with intrinsic superconductivity,the nontrivial topology of the normal state may generate unconventional superconductivity in both bulk and surfaces.Our findings could largely inspire the experimental searching for possible topological superconductivity in these compounds. | Yuting Qian Simin Nie Changjiang Yi Lingyuan Kong Chen Fang Tian Qian Hong Ding Youguo Shi Zhijun Wang Hongming Weng Zhong Fang | 2019 | npj Computational Materials2019，，1： | 1 |
| 13 | Novel Graphene Biosensor Based on the Functionalization of Multifunctional Nano-bovine Serum Albumin for the Highly Sensitive Detection of Cancer Biomarkers显示文摘A simple,convenient,and highly sensitive bio-interface for graphene field-effect transistors(GFETs) based on multifunctional nano-denatured bovine serum albumin(nano-dBSA) functionalization was developed to target cancer bio-markers.The novel graphene–protein bioelectronic interface was constructed by heating to denature native BSA on the graphene substrate surface.The formed nano-d BSA film served as the cross-linker to immobilize monoclonal antibody against car-cinoembryonic antigen(anti-CEA mAb) on the graphene channel activated by EDC and Sulfo-NHS.The nano-dBSA film worked as a self-protecting layer of graphene to prevent surface contamination by lithographic processing.The improved GFETbiosensor exhibited good specificity and high sensitivity toward the target at an ultralow concentration of 337.58 fg mL-1.The electrical detection of the binding of CEA followed the Hill model for ligand–receptor interaction,indicating the negative binding cooperativity between CEA and anti-CEA mAb with a dissociation constant of 6.82×10-10M.The multifunctional nano-dBSA functionalization can confer a new function to graphene-like 2D nanomaterials and provide a promising bio-functionalization method for clinical application in biosensing,nanomedicine,and drug delivery. | Lin Zhou Kun Wang Hao Sun Simin Zhao Xianfeng Chen Dahong Qian Hongju Mao Jianlong Zhao | 2019 | Nano-Micro Letters2019，11，2： | 1 |
| 14 | Generating hyperchaotic Lü attractor via state feedback control显示文摘 | CHEN Aimin LU Junan Lü Jinhu YU Simin | 2006 | Physica A2006，364，： | 1 |
| 15 | The Synthesis of Sub-Nano-Thick Pd Nanobelt-Based Materials for Enhanced Hydrogen Evolution Reaction Activity显示文摘Tailoring atomic structures of noblemetal nanomaterials with size close to single-unit cell range is essential in both fundamental researchand applications,including their development into high catalytic performance materials in renewable,green energy conversions,devices for energy storage,and as biosensors for environmental pollutants.However,several strategies used in fabricating these materials still impose enormous challenges,arising from lack of even size distribution,shape uniformity,and controlled composition,which are critical in determining their specific activities and efficiencies.Herein,we report a facile approach for preparing sub-nano-thick palladium nanobelt-based(PdNB)materials.Then we rationalized the formation mechanism of such highly anisotropic structures by morphology-related thermodynamic and kinetic analysis.Moreover,we investigated if electrocatalysis performance of these NB-basedmaterialswere enhanced.Thepalladium(Pd)NBs featured a thickness of∼0.9-1.2 nm and width of 5-18nmwith length extending to severalmicrometers[denoted as Pd(0.9)],or a thickness of∼0.7-0.9 nm and width of 2.5-6 nmwith length of several hundreds of nanometers[denoted as Pd(0.7)].According to our theoretical analysis,one-dimensional(1D)growth encountered almost no energy barrier at optimal reaction conditions,whereas the growth of Pd nanostructures with other dimensions confronted high barriers,indicating that it was plausible to prepare 1D structures with sizes close to single-unit cells.Also,platinum(Pt)could be successfully doped into the Pd(0.9)NBs through a galvanic epitaxial growth,forming edge-Pt-enriched Pd NBs(eePtPd NBs).Further,electron transfer from Pd to Pt imparted the eePtPd NBs with high hydrogen evolution reaction(HER)activity.The eePtPd NBs showed a 3.5 and 1.8 times higher in exchange current density and mass activity(at−0.1 V),respectively,compared to those of Pt catalysts in perchloric acid(HClO_(4))solutions.Finally,the NBs all showed high activity toward ethanol and formic acid oxidation reactions.Our current work aids in gaining insights into tailoring Pd nanostructures at an atomic level and provides Pd sub-nanometric 1D structures for further research.Moreover,our morphology-related thermodynamic and kinetic analysis extend our understanding of the control of nanostructure morphology and might shed light on the precision of designing specific morphologies of noble metal nanocrystal structures. | Bing Ni Qinghua Zhang Chen Ouyang Simin Zhang Biao Yu Jing Zhuang Lin Gu Xun Wang | 2020 | CCS Chemistry2020，2，1： | 1 |
| 16 | A modulebased and unified approach to chaotic circuit design and its applications显示文摘 | YU Simin Lü Jinhu CHEN Guanrong | 2007 | International Journal of Bifurcation and Chaos2007，17，5： | 1 |
| 17 | Design and implementation of n-scroll chaotic attractors from a general jerk circuit 显示文摘 | Simin Yu Jinhu Lu Leung H Guanrong Chen | 2005 | Circuits and Systems 1 (S1549-8328)2005，52，7： | 1 |
| 18 | Synthesis, Crystal Structure, and Visible Light Responses of Ti4Cu4-Oxo Clusters with Mixed Valence Copper Ions显示文摘Summaryof main observation and conclusion In order to extend the absorption spectrum of polyoxo-titanium clusters into the visible region,two new heterometal-oxo clusters Ti4CuII2CuI2(μ3-O)6(benzoate)10(MeCN)4(PTC-153)and Ti4CuII2CuI2(μ3-O)6(benzoate)8(CH3COO)2(MeCN)4(PTC-154)were success-fully synthesized.Single-crystal X-ray diffraction and X-ray photoelectron spectroscopy studies showed that these two heterometallic Ti4Cu4-oxo clusterspossessed Chinese knot-shape structure and mixed valence Cu^1+/2+ions.UV-visible spectroscopyanalysis demonstrated that the visible light region ab-sorption of PTC-153and PTC-154 could be significantly enhanced by doping copper.Furthermore,their visible-light driven photocurrent responses were studied by using samples of PTC-153and PTC-154as electrode precursors. | Simin Hou Shumei Chen Jian Zhang Lei Zhang | 2020 | Chinese Journal of Chemistry2020，38，1： | 1 |
| 19 | Effects of soil organism interactions and temperature on carbon use efficiency in three different forest soils显示文摘Microbial carbon use efficiency(CUE)affects the soil C cycle to a great extent,but how soil organisms and the abiotic environment combine to influence CUE at a regional scale remains poorly understood.In the current study,microcosms were used to investigate how microbial respiration,biomass,and CUE responded to biotic and abiotic factors in natural tropical,subtropical,and temperate forests.Soil samples from the forests were collected,sterilized,and populated with one or a combination of three types of soil organisms(the fungus Botrytis cinerea,the bacterium Escherichia coli,and the nematode Caenorhabditis elegans).The microcosms were then kept at the mean soil temperatures of the corresponding forests.Microbial respiration,biomass,and CUE were measured over one-month incubation period.The results showed that microbial biomass and CUE were significantly higher,but microbial respiration lower in the subtropical and temperate forest soils than in tropical forest soil.Biotic factors mainly affected CUE by their effect on microbial biomass,while temperature affected CUE by altering respiration.Our results indicate that temperature regulates the interactive effects of soil organisms on microbial biomass,respiration,and CUE,which would provide a basis for understanding the soil C cycle in forest ecosystems. | Simin Wang Xiaoyun Chen Debao Li Jianping Wu | 2021 | Soil Ecology Letters2021，3，2： | 1 |
| 20 | Chromatin-associated SUMOylation controls the transcriptional switch between plant development and heat stress responses显示文摘The post-translational protein modification known as SUMOylation has conserved roles in the heat stress responses of various species.The functional connection between the global regulation of gene expression and chromatin-associatedSUMOylation in plant cells isunknown.Here,weuncovereda genome-wide relationship between chromatin-associated SUMOylation and transcriptional switches in Arabidopsis thaliana grown at room temperature,exposed to heat stress,and exposed to heat stress followed by recovery.The small ubiquitin-like modifier(SUMO)-associated chromatin sites,characterized by whole-genome ChIP-seq,were generally associated with active chromatin markers.In response to heat stress,chromatin-associated SUMO signals increased at promoter-transcriptional start site regions and decreased in gene bodies.RNAseq analysis supported the role of chromatin-associatedSUMOylation in transcriptional activation during rapid responses to high temperature.Changes inSUMOsignals on chromatinwere associated with the upregulation of heat-responsivegenesandthedownregulation ofgrowth-relatedgenes.Disruption of theSUMOligasegene SIZ1 abolished SUMOsignals on chromatin and attenuated rapid transcriptional responses to heat stress.The SUMO signal peaks were enriched in DNA elements recognized by distinct groups of transcription factors under different temperature conditions.These observations provide evidence that chromatin-associated SUMOylation regulates the transcriptional switch between development and heat stress response in plant cells. | Danlu Han Chen Chen Simin Xia Jun Liu Jie Shu Vi Nguyen Jianbin Lai Yuhai Cui Chengwei Yang | 2021 | Plant Communications2021，2，1： | 1 |
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