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| 1 | Southern rice black-streaked dwarf virus:A new proposed Fijivirus species in the family Reoviridae显示文摘For the past several years, a novel dwarf disease has been observed on rice (Oryza sativa) in some regions of Guangdong Province and Hainan Province, southern China. Infected plants showed stunting, dark leaf and small enations on stem and leaf back. Typical Fijivirus viroplasma containing crystalline arrayed spherical virons approximately 70―75 nm in diameter and tubular structures were detected in ultrathin sections by an electron microscope in parenchyma phloem cells of the infected plants. The virus was transmitted to rice seedlings by white-backed planthoppers, Sogatella furcifera (Hemiptera: Delphacidae), collected in the diseased fields. Analysis of dsRNA extracts from infected plants revealed ten linear segments, which were similar to the electrophoretic profile of Rice black-streaked dwarf virus (RBSDV). RT-PCR with a single primer which matched to a linker sequence ligated to both 3′ ends of the viral genomic dsRNAs resulted in amplification of genome segments 9 (S9) and 10 (S10) cDNA products. The complete nucleotide sequences of S9 and S10 were obtained from clones of the RT-PCR amplicon exhibited characteristic properties of Fijivirus including low GC content (34.5% and 35.6%), genus conserved 5′ and 3′ termini sequences and similar genome organization. Blast searches indicated that the sequences of S9 and S10 shared 68.8%―74.9% and 67.1%―77.4% nucleotide identities with those of viruses in the Fijivirus group 2, respectively. These values were similar to those among other viruses in the Fijivirus group 2 and considerably lower than those among RBSDV isolates. Phylogenetic trees based on S9 and S10 nucleotide sequences and their putative amino acid sequences showed that this virus represented a separate branch among other Fijiviruses. The virus was also detected by a nested RT-PCR assay in corn (Zea mays), barnyard grass (Echinochloa crusgalli), Juncellus serotinus and flaccidgrass (Pennisetum flaccidum) in and/or adjacent to the infected rice fields. It is proposed that this virus be considered as a new species, Southern rice black-streaked dwarf virus, in the group 2 of the genus Fijivirus in the family Reoviridae. | ZHOU GuoHui WEN JingJung CAI DeJiang LI Peng XU DongLin ZHANG ShuGuang | 2008 | Chinese Science Bulletin2008，53，23： | 124 |
| 2 | Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury显示文摘The outbreak of the 2019-nCoV infection began in December 2019 in Wuhan,Hubei province,and rapidly spread to many provinces in China as well as other countries.Here we report the epidemiological,clinical,laboratory,and radiological characteristics,as well as potential biomarkers for predicting disease severity in 2019-nCoV-infected patients in Shenzhen,China.All 12 cases of the 2019-nCoV-infected patients developed pneumonia and half of them developed acute respiratory distress syndrome (ARDS).The most common laboratory abnormalities were hypoalbuminemia,lymphopenia,decreased percentage of lymphocytes (LYM) and neutrophils (NEU),elevated C-reactive protein (CRP) and lactate dehydrogenase (LDH),and decreased CD8 count.The viral load of 2019-nCoV detected from patient respiratory tracts was positively linked to lung disease severity.ALB,LYM,LYM (%),LDH,NEU (%),and CRP were highly correlated to the acute lung injury.Age,viral load,lung injury score,and blood biochemistry indexes,albumin (ALB),CRP,LDH,LYM (%),LYM,and NEU (%),may be predictors of disease severity.Moreover,the Angiotensin Ⅱlevel in the plasma sample from 2019-nCoV infected patients was markedly elevated and linearly associated to viral load and lung injury.Our results suggest a number of potential diagnosis biomarkers and angiotensin receptor blocker (ARB) drugs for potential repurposing treatment of 2019-nCoV infection. | Yingxia Liu Yang Yang Cong Zhang Fengming Huang Fuxiang Wang Jing Yuan Zhaoqin Wang Jinxiu Li Jianming Li Cheng Feng Zheng Zhang Lifei Wang Ling Peng Li Chen Yuhao Qin Dandan Zhao Shuguang Tan Lu Yin Jun Xu Congzhao Zhou Chengyu Jiang Lei Liu | 2020 | Science China(Life Sciences)2020，63，3： | 157 |
| 3 | Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells显示文摘人的导致的 pluripotent 茎(iPS ) 房间类似于胚胎的茎(ES ) 房间,和罐头强烈地增殖并且区分进许多房间类型。然而,人的 iPS 房间的肝的区别还没被报导了。在这份报告,人的 iPS 房间被导致由一个逐步的协议区分进肝的房间。肝房间标记的表达式和人的 iPS 的肝相关的函数导出房间的房间被监视并且与区分的人的 ES 房间和主要人的 hepatocytes 的相比。在白天 7 点的约 60% 区分的人的 iPS 房间表示了肝的标记 alpha fetoprotein 和白长袍的。在白天 21 点的区分的房间包括白朊 Asecretion,肝糖合成,脲生产和可诱导的细胞色素 P450 活动展出了肝房间功能。肝的标记的表示和 iPS 的肝相关的功能导出房间的肝的房间比得上人的 ES 导出房间的肝的房间的。这些结果证明人的 iPS 房间,类似于人的 ES 房间,能高效地被导致区分房间进象 hepatocyte 一样。 | Zhihua Song Jun Cai Yanxia Liu Dongxin Zhao Jun Yong Shuguang Duo Xijun Song Yushan Guo Yang Zhao Han Qin Xiaolei Yin Chen Wu Jie Che Shichun Lu Mingxiao Ding Hongkui Deng | 2009 | Cell Research2009，19，11： | 63 |
| 4 | Cold-chain food contamination as the possible origin of COVID-19 resurgence in Beijing显示文摘COVID-19,caused by SARS-CoV-2[1,2],has been contained in China through stringent non-pharmaceutical interventions.Border control and quarantine have effectively prevented the virus from being spread by infected travellers,but the risk of resurgence caused by other routes of introduction and transmission remains unclear,and current strategies to prevent resurgence could be flawed.Since July,SARS-CoV-2 RNA contaminations in frozen food imported from countries with ongoing epidemics have been reported in nine provinces in China[3,4].However,there is no robust evidence of COVID-19 outbreaks initiated by environmentto-human transmission.Here we add to evidence of such transmission by investigating the recent COVID-19 resurgence in Beijing. | Xinghuo Pang Lili Ren Shuangsheng Wu Wentai Ma Jian Yang Lin Di Jie Li Yan Xiao Lu Kang Shichang Du Jing Du Jing Wang Gang Li Shuguang Zhai Lijuan Chen Wenxiong Zhou Shengjie Lai Lei Gao Yang Pan Quanyi Wang Mingkun Li Jianbin Wang Yanyi Huang Jianwei Wang COVID-19 Field Response Group COVID-19 Laboratory Testing Group | 2020 | National Science Review2020，7，12： | 51 |
| 5 | Coking wastewater treatment for industrial reuse purpose: Combining biological processes with ultrafiltration, nanofiltration and reverse osmosis显示文摘A full-scale plant using anaerobic, anoxic and oxic processes (A1/A2/O), along with a pilot-scale membrane bioreactor (MBR), nanofiltration (NF) and reverse osmosis (RO) integrated system developed by Shanghai Baosteel Chemical Co. Ltd., was investigated to treat coking wastewater for industrial reuse over a period of one year. The removals reached 82.5% (COD), 89.6% (BOD), 99.8% (ammonium nitrogen), 99.9% (phenol), 44.6% (total cyanide (T-CN)), 99.7% (thiocyanide (SCN-)) and 8.9% (fluoride), during the A1/A2/O biological treatment stage, and all parameters were further reduced by over 96.0%, except for fluoride (86.4%), in the final discharge effluent from the currently operating plant. The pilot-scale MBR process reduced the turbidity to less than 0.65 NTU, and most of the toxic organic compounds were degraded or intercepted by the A1/A2/O followed MBR processes. In addition, parameters including COD, T-CN, total nitrogen, fluoride, chloride ion, hardness and conductivity were significantly reduced by the NF-RO system to a level suitable for industrial reuse, with a total water production ratio of 70.7%. However, the concentrates from the NF and RO units were highly polluted and should be disposed of properly or further treated before being discharged. | Xuewen Jin Enchao Li Shuguang Lu Zhaofu Qiu Qian Sui | 2013 | Journal of Environmental Sciences2013，25，8： | 38 |
| 6 | Magmatism during continental collision, subduction, exhumation and mountain collapse in collisional orogenic belts and continental net growth: A perspective显示文摘Continental orogens on Earth can be classified into accretionary orogen and collisional orogen.Magmatism in orogens occurs in every periods of an orogenic cycle,from oceanic subduction,continental collision to orogenic collapse.Continental collision requires the existence of prior oceanic subduction zone.It is generally assumed that the prerequisite of continental deep subduction is oceanic subduction and its drag force to the connecting passive-margin continental lithosphere during continental collision.Continental subduction and collision lead to the thickening and uplift of crust,but the formation time of the related magmatism in orogens depends on the heating mechanism of lithosphere.The accretionary orogens,on the other hand,have no strong continental collision,deep subduction,no large scale of crustal thrusting,thickening and uplift,and no UHP eclogite-facies metamorphic rocks related to continental deep subduction.Even though arc crust could be significantly thickened during oceanic subduction,it is still doubtful that syn-or post-collisional magmatism would be generated.In collisional orogens,due to continental deep subduction and significant crustal thickening,the UHP metamorphosed oceanic and continental crusts will experience decompression melting during exhumation,generating syn-collisional magmatism.During the orogen unrooting and collapse,post-collisional magmatism develops in response to lithosphere extension and upwelling of asthenospheric mantle,marking the end of an orogenic cycle.Therefore,magmatism in orogens can occur during the continental deep subduction,exhumation and uplift after detachment of subducted oceanic crust from continental crust,and extensional collapse.The time span from continental collision to collapse and erosion of orogens(the end of orogenic cycle)is 50–85 Myr.Collisional orogens are the key sites for understanding continental deep subduction,exhumation,uplift and orogenic collapse.Magmatism in collisional orogens plays important roles in continental reworking and net growth. | SONG ShuGuang WANG MengJue WANG Cao NIU YaoLing | 2015 | Science China Earth Sciences2015，58，8： | 39 |
| 7 | Decoupling of surface and subsurface sutures in the Dabie orogen and a continent-collisional lithospheric-wedging model: Sr-Nd-Pb isotopic evidences of Mesozoic igneous rocks in eastern China显示文摘There are significant differences of Nd and Pbisotopic compositions between Mesozoic mafic igneous rocks from the North China Block (NCB) and the South ChinaBlock (SCB). Mesozoic mantle-derived igneous rocks fromthe North China Block have very low e Nd values (-15 to -21), and 206Pb/204Pb ratios (< 17.9), while those in the SCB are characterized by e Nd > -10 and 206Pb/204Pb > 18.3. The verylow e Nd values (-16 to -20) and 206Pb/204Pb ratios (< 17.3) of the early Cretaceous mafic-ultramafic intrusions developedin the north part of the Dabie orogen (NDZ) suggest that the deep lithosphere underneath the NDZ belongs to the NCBbut not the SCB. Therefore, although the surface suture be-tween the NCB and SCB is located on the north side of theNDZ, the subsurface suture between the NCB and SCBshould be located to the south side of the NDZ. This is con-sistent with the previous suggestion that the subsurface su-ture in the Sulu terrane east of the Tanlu fault was the south displacement, but contradictory to northward continentalsubduction of the SCB. A continent-collisional lithospheric-wedging model can interpret the decoupling of the surface and subsurface sutures in the Dabie-Sulu orogen. After slabbreak-off, the continuing convergence of two continental blocks must increase the compression force acting on the suture zone, which might induce the lithosphere splitting of SCB. Thus, the lower crust and lithospheric mantle on thesouth margin of the NCB can wedge into the north margin of the lithosphere of the SCB along the Dabie-Sulu collisionzone. This process caused the overthrust of the mid-upper continental crust with exhumed ultrahigh pressure meta-morphic (UHPM) rocks and underthrust of the deep litho-sphere of the SCB. It could be an important mechanism re-sponsible for the second rapid cooling and uplifting of theUHPM rocks and lithospheric delamination as well as thecorresponding magmatism in Jurassic in the Dabie orogen.The southward movement of subsurface suture in theDabie-Sulu orogen may also provide a tectonic setting indepth for the large-scale Mesozoic magmatic-metallogenesis along the middle-lower reaches of the Yangtse River in east-ern China. | LI Shuguang & YANG Wei School of Earth and Space Sciences, University of Science and Tech-nology of China, Hefei 230026, China | 2003 | Chinese Science Bulletin2003，48，8： | 37 |
| 8 | SHRIMP zircon U-Pb ages for the Paleoproterozoic metamorphic-magmatic events in the southeast margin of the North China Craton显示文摘A garnet-pyroxene bearing amphibolite as a xenolith hosted by the Mesozoic igneous rocks from Xuzhou-Suzhou area was dated by zircon SHRIMP U-Pb method, which yields a metamorphic age of 1918 ± 56 Ma. In addition, the zircons from a garnet amphibolite as a lens interbedded with marble in the Archean metamorphic complex named Wuhe group in the Bengbu uplift give a metamorphic U-Pb age of 1857 ± 19 Ma, and the zircons from Shimenshan deformed granite in the eastern margin of the Bengbu uplift give a magma crystallization U-Pb age of 2054 ± 22 Ma. Both the Xuzhou-Suzhou area and Bengbu uplift are located in the southeastern margin of the North China Craton. Therefore,these ages indicate that there is a Paleoproterozoic tectonic zone in the southeastern margin of the North China Craton, and its metamorphic and magmatic ages are consistent with those of the other three Paleoproterozoic tectonic zones in the North China Craton. In view of the large scale sinistral strike-slip movement occurred at the Mesozoic along the Tan-Lu fault zone, the position of the eastern Shandong area, which is a south section of the Paleoproterozoic Jiao-Liao-Ji Belt, was correlated to Xuzhou-Suzhou-Bengbu area prior to movement of the Tan-Lu fault zone. This suggests that the Xuzhou-Suzhou-Bengbu Paleoproterozoic tectonic zone might be a southwest extension of the Paleoproterozoic Jiao-Liao-Ji Belt. | GUO SuShu LI ShuGuang | 2009 | Science China Earth Sciences2009，52，8： | 33 |
| 9 | Early Paleozoic granite in Nujiang River of northwest Yunnan in southwestern China and its tectonic implications显示文摘沿着在西方的云南的中国缅甸边阶的 Nujiang 区域收到了很多注意并且被认为是西藏的高原的向东南的逃跑的重要隧道。这条隧道被红 River-Ailao 山左文字的 strick 滑倒差错在这条隧道以内在西方在东方和英雄传奇 Gaoligong 正确文字的 strick 滑倒差错毗邻,它仍然不对贡尚·布洛克哪个构造单位合适清楚。尽管一些研究人员建议它是 Sundaland 岩层的北方结束,它的构造定义是相当模糊的。这篇论文报导我们 U-Pb 同位素的 geochronological 在贡尚·布洛克以内在 Gudang 片麻岩的花岗石上学习的新锆石。这研究在理解起源和西北的云南的构造环境起一个重要作用。 | SONG ShuGuang JI JianQing WEI ChunJing SU Li ZHENG YaDong SONG Biao ZHANG LiFei | 2007 | Chinese Science Bulletin2007，52，17： | 31 |
| 10 | Forming age and tectono-petrogenises of the Jiugequan ophiolite in the North Qilian Mountain,NW China显示文摘The Jiugequan ophiolite is one of the representative ophiolite fragments in the Early Paleozoic orogenic belt of the North Qilian Mountain.It has been drawn much attention and extensively studied in recent years.In this study,ion microprobe(SHRIMP) U-Pb dating was carried out for zircons from isotropic gabbro from the Jiugequan ophiolite.Eighteen analyses yield a relatively consistent apparent 206Pb/238U ages from 480 to 508 Ma with a weighted mean age of 490±5 Ma(MSWD=1.06),which is believed to be the crystallization age of the gabbro and thus the forming age of the Jiugequan ophiolite.Major and trace element geochemical study indicates that the diabase-basalts from the Jiugequan ophiolite have N-MORB and E-MORB characteristics with some subduction-related signatures.The petrological,geochemical and chronological data enable us to conclude that the Jiugequan ophiolite is most likely to be formed at a spreading center of back-arc basin during the early Ordovician,while the ancient Qilian oceanic plate subducted northwards.The acquisition of forming age and determination of tectonic setting for Jiugequan ophiolite provide significant constraints on the evolution of intra-oceanic subduction system in the North Qilian orogenic belt during the Early Paleozoic era. | XIA XiaoHong SONG ShuGuang | 2010 | Chinese Science Bulletin2010，55，18： | 33 |
| 11 | Detachment within subducted continental crust and multi-slice successive exhumation of ultrahigh-pressure metamorphic rocks: Evidence from the Dabie-Sulu orogenic belt显示文摘Although tectonic models were presented for exhumation of ultrahigh-pressure (UHP) metamorphic rocks during the continental collision, there is increasing evidence for the decoupling between crustal slices at various depths within deeply subducted continental crust. This lends support to the multi-slice successive exhumation model of the UHP metamorphic rocks in the Dabie-Sulu orogen. The available evidence is summarized as follows: (1) the low-grade metamorphic slices, which have geotectonic affinity to the South China Block and part of them records the Triassic metamorphism, occur in the northern margin of the Dabie-Sulu UHP metamorphic zone, suggesting decoupling of the upper crust from the underlying basement during the initial stages of continental subduction; (2) the Dabie and Sulu HP to UHP metamorphic zones comprise several HP to UHP slices, which have an increased trend of metamorphic grade from south to north but a decreased trend of peak metamorphic ages correspondingly; and (3) the Chinese Continental Science Drilling (CCSD) project at Donghai in the Sulu orogen reveals that the UHP metamorphic zone is composed of several stacked slices, which display distinctive high and low radiogenic Pb from upper to lower parts in the profile, suggesting that these UHP crustal slices were derived from the subducted upper and middle crusts, respectively. Detachment surfaces within the deeply subducted crust may occur either along an ancient fault as a channel of fluid flow, which resulted in weakening of mechanic strength of the rocks adjacent to the fault due to fluid-rock interaction, or along the low-viscosity zones which resulted from variations of geotherms and lithospheric compositions at different depths. The multi-slice successive exhumation model is different from the traditional exhumation model of the UHP metamorphic rocks in that the latter assumes the detachment of the entire subducted continental crust from the underlying mantle lithosphere and its subsequent exhumation as a whole. This also reveals the difference between the continental subduction and oceanic subduction. In addition, several important proposals concerning the multi-slice successive exhumation model are made for further studies. | LIU YiCan LI ShuGuang | 2008 | Chinese Science Bulletin2008，53，20： | 28 |
| 12 | Qi-Qin Accretionary Belt in Central China Orogen: accretion by trench jam of oceanic plateau and formation of intra-oceanic arc in the Early Paleozoic Qin-Qi-Kun Ocean显示文摘Most orogenic belts have experienced a complex accretionary process with multiple episodes of sea?oor subduction and trench retreat.This accretionary process is important in continenta development and growth[1,2].Three giant orogens extend in China,e.g.,the Central Asian Orogen in the north,the Central China Orogen in the middle and the Himalayan Orogen in the southwest.They are keys for the formation of the Eurasian continent(Fig.1a).The Central China Orogen | Shuguang Song Liming Yang Yuqi Zhang Yaoling Niu Chao Wang Li Su Yanlin Gao | 2017 | Science Bulletin2017，62，15： | 28 |
| 13 | Process and mechanism of mountain-root removal of the Dabie Orogen—Constraints from geochronology and geochemistry of post-collisional igneous rocks显示文摘Systematical studies of post-collisional igneous rocks in the Dabie orogen suggest that the thickened mafic lower crust of the orogen was partially melted to form low-Mg#adakitic rocks at 143–131 Ma.Delamination and foundering of the thickened mafic lower crust occurred at 130 Ma,which caused the mantle upwelling and following mafic and granitic magmatic intrusions.Migmatite in the North Dabie zone,coeval with the formation of low-Mg#adakitic intrusions in the Dabie orogen,was formed by partial melting of exhumed ultrahigh-pressure metamorphic rocks at middle crustal level.This paper argues that the partial melting of thickened lower and middle crust before mountain-root collapse needs lithospheric thinning.Based on the geothermal gradient of6.6°C/km for lithospheric mantle and initial partial melting temperature of^1000°C for the lower mafic crust,it can be estimated that the thickness of lithospheric mantle beneath thickened lower crust has been thinned to<45 km when the thickened lower crust was melting.Thus,a two-stage model for mountain-root removal is proposed.First,the lithospheric mantle keel was partially removal by mantle convection at 145 Ma.Loss of the lower lithosphere would increase heat flow into the base of the crust and would cause middle-lower crustal melting.Second,partial melting of the thickened lower crust has weakened the lower crust and increased its gravity instability,thus triggering delamination and foundering of the thickened mafic lower crust or mountain-root collapse.Therefore,convective removal and delamination of the thickened lower crust as two mechanisms of lithospheric thinning are related to causality. | LI ShuGuang HE YongSheng WANG ShuiJiong | 2013 | Chinese Science Bulletin2013，58，35： | 25 |
| 14 | The Hardy Rubber Tree Genome Provides Insights into the Evolution of Polyisoprene Biosynthesis显示文摘Eucommia ulmoides,也叫的强壮的橡胶树,是一棵经济地重要的树;然而,它的染色体顺序的缺乏 ?限制基本生物研究和这植物种的应用研究。这里,我们在场它的 1.2-Gb 染色体的一个高质量的集会(支架 N50 ?=? 1.88 Mb ) 与至少 26 ? 为 E 的 723 预言的基因。ulmoides,顺序 Garryales 的首先定序的染色体,它用联合定序的 Illumina 的综合策略被获得,定序的 PacBio,和印射的 BioNano。作为到 lamiids 和 campanulids 的姐妹 taxon, E。ulmoides 经历了三倍由核心 eudicots 而是没有进一步整个染色体的复制分享了的一个古老的染色体 ? 在最后 1.25 亿年里。E。ulmoides 为涉及压力回答和第二等的代谢物的生合成的多重基因展出高表达式层次或基因数字扩大,它可以说明它的可观的环境适应性。与橡胶树(Hevea brasiliensis ) 相对照,它生产 cis 聚异式戊二我烯, E。ulmoides 演变综合经由 farnesyl diphosphate synthases (FPS ) 的长链的 trans 聚异式戊二我烯。而且, FPS 和橡胶延伸 factor/small 橡胶粒子蛋白质基因家庭从 H 独立地被扩展。brasiliensis 系。这些结果提供新卓见进 E. 的生物学 ? ulmoides 和聚异式戊二我烯生合成的起源。 | Ta-na Wuyun Lin Wang Huimin Liu Xuewen Wang Liangsheng Zhang Jeffrey L. Bennetzen Tiezhu Li Lirong Yang Panfeng Liu Lanying Du Lu Wang Mengzhen Huang Jun Qing Iili Zhu Wenquan Bao Hongguo Li Qingxin Du Jingle Zhu Hong Yang Shuguang Yang Hui Liu Hui Yue Jiang Hu Suoliang Yu Yu Tian Fan Liang Jingjing Hu Depeng Wang Ruiwen Gao Dejun Li Hongyan Du | 2018 | Molecular Plant2018，11，3： | 24 |
| 15 | Post-collisional lithosphere delamination of the Dabie-Sulu orogen显示文摘The consistence between the first rapid cooling time (226-219 Ma) of the untrahigh pressure metamorphic (UHPM) rocks in the Dabie Mountains and the formation time (205-220 Ma) of the syncollisional granites in the Qinling and Sulu areas suggests that the first rapid cooling and uplift of the UHPM rocks may be related to breakoff of subducted plate. Therefore the second rapid cooling and uplift (180-170 Ma) of the UHPM racks needs a post-colli-sional lithosphere delamination which resulted in the granitic magmatism with an age of about 170 Ma. In addition, the rapid rising of the Dabie dome in the early Cretaceous (130-110 Ma) and the corresponding large-scale magmatism in the Dabie Mountains need another litho-sphere delamination. The geochronology of the post-collis-ional mafic-ultramafic intrusions and geological relationship between the mafic-ultramafic intrusions and granites suggest that partial melting was initiated in the mantle, and then progressively developed in the crust, suggesting a mantle | Shuguang Li Fang Huang Hui Li | 2002 | Chinese Science Bulletin2002，47，3： | 22 |
| 16 | The geological characteristics of oceanic-type UHP metamorphic belts and their tectonic implications: Case studies from Southwest Tianshan and North Qaidam in NW China显示文摘The geological characteristics of ultrahigh-pressure (UHP) metamorphic belts formed by deep subduction of oceanic crust are summarized in this paper. Oceanic-type UHP metamorphic belt is characterized by its protolithic assemblage of typical oceanic crust, the peak metamorphic temperature <600℃, P-T path undergoing blueschist facies during prograde and retrograde metamorphic evolution, respectively, with low geothermal gradient of cold subduction. The further study of oceanic-type UHP metamorphic belt is very significant for constructing metamorphic reaction series of cold subduction zone, for understanding how aqueous fluids were transported into deep mantle and for classifying the types of UHP metamorphism in cold subduction zone. The uplift and exhumation mechanism of oceanic UHP metamorphic rocks is one of the most challenging problems in the study of UHP metamorphism, which is very important for understanding the geodynamic mechanism of solid Earth. As a traveler subducted into the mantle depth and then uplifted to the surface, oceanic-type UHP metamorphic belts witness the bulk process from the subduction to exhumation and is an ideal target to study the geochemical behavior and cycling of elements in subduction zones. The tectonic evolution of one convergent orogenic belt can be usually divided into two stages of oceanic subduction and followed continental subduction and collision, and the two best-established examples of orogenic belts are Alps and Himalaya. Therefore, the study of oceanic-type UHP metamorphic belt is the frontier of the current plate tectonic theory. As two case studies, the current status and existing problems of oceanic-type UHP metamorphic belts in Southwest Tianshan and North Qaidam, NW China, are reviewed in this paper. | ZHANG LiFei LU Zeng ZHANG GuiBin SONG ShuGuang | 2008 | Chinese Science Bulletin2008，53，20： | 22 |
| 17 | Glucocorticoid receptor and sequential P53 activation by dexamethasone mediates apoptosis and cell cycle arrest of osteoblastic MC3T3-E1 cells显示文摘 | Li Hui Yao Jianfeng Liu Hui Liu Shuguang Xu Peng Ma Jianbing Zhang Yumin | 2012 | 美中国际创伤杂志2012，11，1： | 22 |
| 18 | Advances in the reintroduction of rare and endangered wild plant species显示文摘Human disturbance and climate change have increased the risk of extinction for rare and endangered wild plant species.One effective way to conserve these rare and endangered species is through reintroduction.In this review,we summarize the advances in wild plant reintroduction from five perspectives:the establishment of reintroduction biology as an important tool for biodiversity conservation;the importance of genetic diversity in reintroduction;reintroduction under global climate change;recruitment limitation in reintroduction;and reintroduction and ecological restoration.In addition,we consider the future of plant reintroduction strategies. | REN Hai JIAN ShuGuang LIU HongXiao ZHANG QianMei LU HongFang | 2014 | Science China(Life Sciences)2014，57，6： | 20 |
| 19 | Occurrence, sources and fate of pharmaceuticals and personal care products in the groundwater: A review显示文摘The presence of pharmaceuticals and personal care products(PPCPs)in the aquatic environment may pose potential threat to the ecosystem and human health,hence PPCPs have aroused much concern over the world.The contamination of PPCPs in the groundwater,the main source of drinking water supply in many countries and regions,has been extensively studied in the last decade.This paper reviews the occurrence of frequently detected PPCPs,including antibiotics,anti-inflammatories,lipid-regulators,carbamazepine,caffeine,and N,N-diethyl-m-toluamide in groundwater,with special concern to the progress made over the past three years.Possible emission sources for PPCPs in groundwater,such as wastewater and contaminated surface water,landfills,septic systems,livestock breeding and sewer leakage,are summarized.Besides,adsorption,migration and degradation,the dominant mechanisms in the subsurface transport and fate of PPCPs,are discussed,and the insights into the future study of PPCPs in the groundwater are provided. | Qian Sui Xuqi Cao Shuguang Lu Wentao Zhao Zhaofu Qiu Gang Yu | 2015 | Emerging Contaminants2015，1，1： | 20 |
| 20 | Effect of Fuzhenghuayu decoction on vascular endothelial growth factor secretion in hepatic stellate cells显示文摘Objective: To investigate the effect of Fuzhenghuayudecoction on autocrine activation of hepatic stellatecell (HSC).Methods: The drug serum containing Fuzhenghuayudecoction was collected from normal rats, and cul-tured with activated HSC in vitro. The conditionedmedium from the drug serum treated HSC was addedto primary cultured quiescent HSC. Cell prolifera-tion was assayed by tetrazolium colorimetric test,and the contents of type Ⅰ collagen and vascular endo-thelial growth factor (VEGF) in the supernatantwere measured with ELISA.Results: The conditioned medium from activatedHSC could stimulate the quiescent HSC proliferationand type Ⅰ collagen secretion. The drug serum inhibi-ted this stimulating action and VEGF secretion fromthe activated HSC.Conclusion: Fuzhenghuayu decoction acts effectivelyagainst the autocrine activation pathway of HSC.The mechanism may be associated with the inhibitionof the secretion of VEGF by activated HSC. | Cheng Liu Cun-Meng Jiang Cheng-Hai Liu Ping Liu Yi-Yang Hu From the Institute of Liver Diseases and Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China | 2002 | Hepatobiliary & Pancreatic Diseases International2002，1，2： | 19 |
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