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| 1 | Gut microbiome in acute pancreatitis:A review based on current literature显示文摘The gut microbiome is a complex microbial community,recognized for its potential role in physiology,health,and disease.The available evidence supports the role of gut dysbiosis in pancreatic disorders,including acute pancreatitis(AP).In AP,the presence of gut barrier damage resulting in increased mucosal permeability may lead to translocation of intestinal bacteria,necrosis of pancreatic and peripancreatic tissue,and infection,often accompanied by multiple organ dysfunction syndrome.Preserving gut microbial homeostasis may reduce the systemic effects of AP.A growing body of evidence suggests the possible involvement of the gut microbiome in various pancreatic diseases,including AP.This review discusses the possible role of the gut microbiome in AP.It highlights AP treatment and supplementation with prebiotics,synbiotics,and probiotics to maintain gastrointestinal microbial balance and effectively reduce hospitalization,morbidity and mortality in an early phase.It also addresses novel therapeutic areas in the gut microbiome,personalized treatment,and provides a roadmap of human microbial contributions to AP that have potential clinical benefit. | Bharati Kadamb Patel Kadamb H Patel Madhav Bhatia Shridhar Ganpati Iyer Krishnakumar Madhavan Shabbir M Moochhala | 2021 | World Journal of Gastroenterology2021，27，30： | 10 |
| 2 | Comparative study and systematic review of laparoscopic liver resection for hepatocellular carcinoma显示文摘AIM: To compare the surgical outcomes between laparoscopic liver resection(LLR) and open liver resection(OLR) as a curative treatment in patients with hepatocellular carcinoma(HCC). METHODS: A Pub Med database search was performed systematically to identify comparative studies of LLR vs OLR for HCC from 2000 to 2014. An extensive text word search was conducted, using combinations of search headings such as 'laparoscopy', 'hepatectomy', and 'hepatocellular carcinoma'. A comparative study was also performed in our institution where we analysed surgical outcomes of 152 patients who underwent liver resection between January 2005 to December 2012, of which 42 underwent laparoscopic or hand-assisted laparoscopic resection and 110 underwent open resection. RESULTS: Analysis of our own series and a review of 17 high-quality studies showed that LLR was superior to OLR in terms of short-term outcomes, as patients in the laparoscopic arm were found to have less intraoperative blood loss, less blood transfusions, and a shorter length of hospital stay. In our own series, both LLR and OLR groups were found to have similar overall survival(OS) rates, but disease-free survival(DFS) rates were higher in the laparoscopic arm. CONCLUSION: LLR is associated with better short-term outcomes compared to OLR as a curative treatment for HCC. Long-term oncologic outcomes with regards to OS and DFS rates were found to be comparable in both groups. LLR is hence a safe and viable option for curative resection of HCC. | Wei Qi Leong Iyer Shridhar Ganpathi Alfred Wei Chieh Kow Krishnakumar Madhavan Stephen Kin Yong Chang | 2015 | World Journal of Hepatology2015，7，27： | 7 |
| 3 | Impacts of tourism development on the physical environment of Mussoorie,a hill station in the lower Himalayan range of India显示文摘Tourism in mountainous regions is a significant source of revenue generation. However, it has also been associated with many adverse environmental consequences. This study aims at assessing the negative impacts of the incessant upsurge in tourism development on the physical environment of Mussoorie, a well-known mountain tourist destination in India. The impact indicators for the region were identified and assessed by qualitative and quantitative analysis of field observations. The observations indicated the aggravation of traffic congestion, atmospheric pollution, undisposed solid waste, water scarcity and infrastructure unavailability as the prevalent issues, especially during the peak tourist months. The extent of the consequential damage to the environment was evaluated by conducting an assessment of tourism-induced human disturbance on the natural landscape of the town. Slope, slope aspect, vegetation cover, road network and drainage network were incorporated as thedetermining landscape attributes to prepare thematic maps of landscape quality(perceivable intrinsic properties) and landscape fragility(vulnerability to anthropogenic disturbances) using GIS technique. An absorption capacity map was finally prepared to characterize the study area into regions of different conservation needs. The results identified the need for planning appropriate preservation strategies for different tourist places in the town. The study can be used by the policy makers for implementing the regulatory measures against potential disturbances due to mass-tourism. | Sangeeta SUNDRIYAL Vijay SHRIDHAR Sandeep MADHWAL Kamal PANDEY Vikram SHARMA | 2018 | Journal of Mountain Science2018，15，10： | 5 |
| 4 | International experts consensus guidelines on robotic liver resection in 2023显示文摘The robotic liver resection(RLR)has been increasingly applied in recent years and its benefits shown in some aspects owing to the technical advancement of robotic surgical system,however,controversies still exist.Based on the foundation of the previous consensus statement,this new consensus document aimed to update clinical recommendations and provide guidance to improve the outcomes of RLR clinical practice.The guideline steering group and guideline expert group were formed by 29 international experts of liver surgery and evidence-based medicine(EBM).Relevant literature was reviewed and analyzed by the evidence evaluation group.According to the WHO Handbook for Guideline Development,the Guidance Principles of Development and Amendment of the Guidelines for Clinical Diagnosis and Treatment in China 2022,a total of 14 recommendations were generated.Among them were 8 recommendations formulated by the GRADE method,and the remaining 6 recommendations were formulated based on literature review and experts’opinion due to insufficient EBM results.This international experts consensus guideline offered guidance for the safe and effective clinical practice and the research direction of RLR in future. | Rong Liu Mohammed Abu Hilal Go Wakabayashi Ho-Seong Han Chinnusamy Palanivelu Ugo Boggi Thilo Hackert Hong-Jin Kim Xiao-Ying Wang Ming-Gen Hu Gi Hong Choi Fabrizio Panaro Jin He Mikhail Efanov Xiao-Yu Yin Roland S Croner Yu-Man Fong Ji-Ye Zhu Zheng Wu Chuan-Dong Sun Jae Hoon Lee Marco V Marino Iyer Shridhar Ganpati Peng Zhu Zi-Zheng Wang Ke-Hu Yang Jia Fan Xiao-Ping Chen Wan Yee Lau | 2023 | World Journal of Gastroenterology2023，29，32： | 2 |
| 5 | A novel tuning strategy for multivariable model predictive control显示文摘 | Shridhar R Cooper D J | 1998 | ISA Transactions1998，36，4： | 1 |
| 6 | VEGF and VEGF type C piay an important role in angiogenesis and lymphangiogenesis in human malignant mesothelioma tumours显示文摘 | Shridhar V Bright RK | 1999 | Br J Cancer1999，81，1： | 1 |
| 7 | Complementary electrostatics for the study of DNA base-pair interactions显示文摘 | Shridhar R Gadre Savita S Pundlik | 1997 | J Phys Chem B1997，101，16： | 1 |
| 8 | Identification of underexpressed genes in early-and late-stage primary ovarian tumours by suppression subtraction hybridization显示文摘 | Shridhar V Sen A Chien J | 2002 | Cancer Res2002，62，1： | 1 |
| 9 | Radiation therapy for rectal cancer: current status and future directions显示文摘 | Hoffe S E Shridhar R Biagioli M C | 2010 | Cancer Control2010，17，1： | 1 |
| 10 | Pattern Recognition with Moment Invariant:A Comparative Study and New Results显示文摘 | Belkasim S O Shridhar M Ahmadi M | 1991 | Pattern Recognition1991，24，： | 1 |
| 11 | Pattern recognition with moment invariants:a comparative study and new results显示文摘 | Belkasim S O Shridhar M Ahmadi A | 1991 | Pattern Recognition1991，24，： | 1 |
| 12 | Early detection of ovarian cancer: promise and reality 显示文摘 | Bast RC Jr Urban N Shridhar V | 2002 | Cancer Treat Res2002，107，： | 1 |
| 13 | Network-based survival analysis reveals subnetwork signatures for predicting outcomes of ovarian cancer treatment显示文摘 | Zhang W Ota T Shridhar V | 2013 | PLoS computational biology2013，9，3： | 1 |
| 14 | Does a stacked DNA base pair hydrate better than a hydrogen-bonded one?:an ab initio study显示文摘 | Sivanesan D Babu K Shridhar R Gadre | 2000 | J Phys Chem A2000，104，10： | 1 |
| 15 | Recognition of Handwritten Numerals with Multiple Feature and Multistage Classifier 显示文摘 | Cao J Ahmadi M Shridhar M | 1995 | Pattern Recognition1995，28，2： | 1 |
| 16 | Stereotactic Body Radiation Therapy for Locally Advanced and Borderline Resectable Pancreatic Cancer Is Effective and Well Tolerated显示文摘 | Michael D. Chuong Gregory M. Springett Jessica M. Freilich Catherine K. Park Jill M. Weber Eric A. Mellon Pamela J. Hodul Mokenge P. Malafa Kenneth L. Meredith Sarah E. Hoffe Ravi Shridhar | 2013 | International Journal of Radiation Oncology Biology Physics2013，，3： | 1 |
| 17 | Differential screening of a human chromosome-3 library identifies hepatocyte growth factor-like/macrophage stimulating protein and its receptor in injured lung possible implications for neuroendocrine cell survival 显示文摘 | Willett CG Smith DI Shridhar V | 1997 | JClin Invest1997，99，： | 1 |
| 18 | Visibility impai- ring aerosols in the urban atmosphere of Delhi 显示文摘 | Singh T Khillare P S Shridhar V | 2008 | En- vironmental Monitoring and Assessment2008，141，13： | 1 |
| 19 | Pattern classification using an efficient KNNR显示文摘 | S O Belkasim M Shridhar M Ahmadi | 1992 | Pattern Recognition1992，25，10： | 1 |
| 20 | Structure of ZnO films prepared by oxidation metallic Zinc显示文摘 | Gupta R K Shridhar N Katiyar M | 2002 | Materials Science in Semiconductor Processing2002，5，： | 1 |
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