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| 1 | In-vitro antimicrobial activity of marine actinobacteria against multidrug resistance Staphylococcus aureus显示文摘Objective:To investigate the antibacterial aclivily of marine actinobacteria against multidrug resistance Staphylococcus aureus(MDRSA).Methods:Fifty one actinobacterial strains were isolated from salt pans soil,costal area in Kothapattanam,Ongole,Andhra Pradesh.Primary screening was done using cross-streak method against MDRSA.The bioaclive compounds are extracted from efficient actinobacteria using solvent extraction.The antimicrobial activity of crude and solvent extracts was perfomied using Kirby-Bauer method.MIC for ethyl acetate extract was determined by modified agar well diffusion method.The potent actinobacteria are identified using Nonomura key,Shirling and Gottlieb 1966 with Bergey's manual of determinative bacteriology.Results:Among the fifty one isolates screened for antibacterial activity,SRB25were found efficient against MDRSA.The ethyl acetate extracts showed high inhibition against test organism.MIC test was performed with the ethyl acetate extract against MDRSA and found to be 1 000μg/mL.The isolaled actinobacteria are identified as Streptomyces sp with the help of Nonomura key.Conclusions:The current investigation reveals that the marine actinobacteria from salt pan environment can be able to produce new drug molecules against drug resistant microorganisms. | Sathish Kumar SR Kokati Venkata Bhaskara Rao | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，10： | 5 |
| 2 | Cytogenetic and molecular aberrations of multiple myeloma patients: a single-center study in Singapore显示文摘 | LIM Alvin Soon Tiong LIM Tse Hui SEE Karen Hsu Shien NG Yit Jun TAN Yu Min CHO0 Natasha Swee Lian LIM Sherry Xin Er YEE Yenny LAU Lai Ching TIEN Sim Leng Kumar Sathish TAN Daryl Chen Lung | 2013 | Chinese Medical Journal2013，，10： | 4 |
| 3 | Power system reconfiguration and loss minimization for a distribution systems using "Catfish PSO" algorithm显示文摘在分发系统节省电能的重要方法之一是为损失减小的网络重构。分发网络是互连网孔网络被造;然而,他们被安排在操作光线。分发 feeder 重构是当令人满意时,发现优化网络性能的光线的操作结构操作限制。在网络配置的变化被打开 sectionalizing 执行(通常关门了) 并且密切联系(通常开了) 网络的开关。这些开关以如此的一个方法被改变,网络的光线的结构被维持,所有负担是充满力量的,力量损失被减少,力量质量被提高,并且系统安全被增加。自从开关的地位是非可辨的,分发 feeder 重构是一个复杂非线性的组合问题。这份报纸为解决分发 feeder 重构(DFR ) 建议一个新进化算法(EA ) 为一辆 33 公共汽车和一件 16 公共汽车样品的问题联网最小化,它有效地保证损失。 | K Sathish KUMAR S NAVEEN | 2014 | Frontiers in Energy2014，8，4： | 3 |
| 4 | Interleukin-6 mediates neutrophil mobilization from bone marrow in pulmonary hypertension显示文摘Myeloid cells,such as neutrophils,are produced in the bone marrow in high quantities and are important in the pathogenesis of vascular diseases such as pulmonary hypertension(PH).Although neutrophil recruitment into sites of inflammation has been well studied,the mechanisms of neutrophil egress from the bone marrow are not well understood.Using computational flow cytometry,we observed increased neutrophils in the lungs of patients and mice with PH.Moreover,we found elevated levels of IL-6 in the blood and lungs of patients and mice with PH.We observed that transgenic mice overexpressing Il-6 in the lungs displayed elevated neutrophil egress from the bone marrow and exaggerated neutrophil recruitment to the lungs,resulting in exacerbated pulmonary vascular remodeling,and dysfunctional hemodynamics.Mechanistically,we found that IL-6-induced neutrophil egress from the bone marrow was dependent on interferon regulatory factor 4(IRF-4)-mediated CX3CR1 expression in neutrophils.Consequently,Cx3cr1 genetic deficiency in hematopoietic cells in Il-6-transgenic mice significantly reduced neutrophil egress from bone marrow and decreased neutrophil counts in the lungs,thus ameliorating pulmonary remodeling and hemodynamics.In summary,these findings define a novel mechanism of IL-6-induced neutrophil egress from the bone marrow and reveal a new therapeutic target to curtail neutrophil-mediated inflammation in pulmonary vascular disease. | Jonathan Florentin Jingsi Zhao Yi-Yin Tai Sathish Babu Vasamsetti Scott P.O’Neil Rahul Kumar Anagha Arunkumar Annie Watson John Sembrat Grant C.Bullock Linda Sanders Biruk Kassa Mauricio Rojas Brian B.Graham Stephen Y.Chan Partha Dutta | 2021 | Cellular & Molecular Immunology2021，18，2： | 3 |
| 5 | Translational products of adipose tissue-derived mesenchymal stem cells:Bench to bedside applications显示文摘With developments in the field of tissue engineering and regenerative medicine,the use of biological products for the treatment of various disorders has come into the limelight among researchers and clinicians.Among all the available biological tissues,research and exploration of adipose tissue have become more robust.Adipose tissue engineering aims to develop by-products and their substitutes for their regenerative and immunomodulatory potential.The use of biodegradable scaffolds along with adipose tissue products has a major role in cellular growth,proliferation,and differentiation.Adipose tissue,apart from being the powerhouse of energy storage,also functions as the largest endocrine organ,with the release of various adipokines.The progenitor cells among the heterogeneous population in the adipose tissue are of paramount importance as they determine the capacity of regeneration of these tissues.The results of adipose-derived stemcell assisted fat grafting to provide numerous growth factors and adipokines that improve vasculogenesis,fat graft integration,and survival within the recipient tissue and promote the regeneration of tissue are promising.Adipose tissue gives rise to various by-products upon processing.This article highlights the significance and the usage of various adipose tissue by-products,their individual characteristics,and their clinical applications. | Shilpa Sharma Sathish Muthu Madhan Jeyaraman Rajni Ranjan Saurabh Kumar Jha | 2021 | World Journal of Stem Cells2021，13，10： | 3 |
| 6 | Nanofat: A therapeutic paradigm in regenerative medicine显示文摘Adipose tissue is a compact and well-organized tissue containing a heterogeneous cellular population of progenitor cells,including mesenchymal stromal cells.Due to its availability and accessibility,adipose tissue is considered a“stem cell depot.”Adipose tissue products possess anti-inflammatory,anti-fibrotic,antiapoptotic,and immunomodulatory effects.Nanofat,being a compact bundle of stem cells with regenerative and tissue remodeling potential,has potential in translational and regenerative medicine.Considering the wide range of applicability of its reconstructive and regenerative potential,the applications of nanofat can be used in various disciplines.Nanofat behaves on the line of adipose tissuederived mesenchymal stromal cells.At the site of injury,these stromal cells initiate a site-specific reparative response comprised of remodeling of the extracellular matrix,enhanced and sustained angiogenesis,and immune system modulation.These properties of stromal cells provide a platform for the usage of regenerative medicine principles in curbing various diseases.Details about nanofat,including various preparation methods,characterization,delivery methods,evidence on practical applications,and ethical concerns are included in this review.However,appropriate guidelines and preparation protocols for its optimal use in a wide range of clinical applications have yet to be standardized. | Madhan Jeyaraman Sathish Muthu Shilpa Sharma Charan Ganta Rajni Ranjan Saurabh Kumar Jha | 2021 | World Journal of Stem Cells2021，13，11： | 2 |
| 7 | Optimization of WDM lightwave systems (BAC) design using error control coding显示文摘 | Mruthyunjaya H S Umesh G Sathish Kumar M | 2007 | Optical Fiber Technology2007，13，2： | 1 |
| 8 | The differential stabilityof the left and right domains of papain显示文摘 | Sathish H A Kumar P R Prakash V | 2009 | ProcessBiochem2009，44，7： | 1 |
| 9 | Protective effect of Centella asiatica on antioxidant tissue defense system against adriamycin induced cadiomyopathy in rats 显示文摘 | Gnanpragasam A Kumar Ebenezar K Sathish V | 2004 | Life Sci2004，76，： | 1 |
| 10 | Modeling of urban growth dynamics and its impact on surface runoff charac- teristics显示文摘 | Sathish Kumar D Arya D Vojinovic Z | 2013 | Computers Environment and Urban Systems2013，41，： | 1 |
| 11 | Synthesis of ZnO and its surfactant based electrode for the simultaneous detection of dopamine and ascorbic acid显示文摘 | KUMAR M SWAMY B E K SATHISH REDDY | 2013 | Anal Methods2013，5，1： | 1 |
| 12 | In-situ preparation of heteropolytungstic acid on TiMCM-41 nanoporous framework for photocatalytic degradation of textile dye methyl orange显示文摘 | PUGAZHENTHIRAN N RAMKUMAR S SATHISH KUMAR P | 2010 | Microporous Mesoporous Mater2010，131，123： | 1 |
| 13 | Vaccine delivery system for tuberculosis based on nano-sized hepatitis B virus core protein particles显示文摘 | Sathish Mundayoor Dhanasooraj Kumar | 2013 | 2013 (defa)2013，，： | 1 |
| 14 | Effect of loaded silver nanoparticles on TiO2 for photocatalyric degradation of acid Red 88显示文摘 | Anandan S Sathish Kumar P Pugazhenthiran N | 2008 | Solar Energy Mater Solar Cells2008，92，8： | 1 |
| 15 | Posterior reversible encephalopathy syndrome unmasking acute glomerulonephritis 显示文摘 | Sathish KS Kumar M Schobhana S | 2014 | Journal of Clinical and Diagnostic Research2014，8，1： | 1 |
| 16 | Isolation and characterization of tyrosinase produced by marine actinobacteria and its application in the removal of phenol from aqueous environment显示文摘现在的学习集中于屏蔽和海洋的 actinobacteria 和它的应用程序从水的答案在酉分的混合物移动生产的 tyrosinase 酶的描述。20 紧张的一个总数从海洋的沉积样品被孤立并且由使用脱脂牛乳琼脂媒介为 tyrosinase 屏蔽了生产。在 20 之中孤立,二孤立显示出的 LK-4 和 LK-20 水解作用和这些的地区为由使用酷氨酸琼脂媒介的第二等的屏蔽被拿。基于第二等的屏蔽 LK-4 的结果为进一步的分析被选择,例如 tyrosinase 试金,蛋白质内容和酶的特定的活动。tyrosinase 酶在 SS 媒介被生产并且被铵硫酸盐降水,分离和 SDS 页部分净化。isolate (LK-4 ) 用 16S rRNA 基因定序作为 Streptomyces espinosus 被识别并且作为 Streptomyces espinosus 紧张 LK4 (KF806735 ) 说出。tyrosinase 酶在被使用把酉分的混合物从水移开的钠 alginate 被使不能调动。酶高效地在显示了 Streptomyces espinosus 紧张 LK-4 生产的那 tyrosinase 酶的很少小时以内把酉分的混合物从水的答案移开能 potently 在工业从废水为酚和酉分的混合物的移动被使用。 | Suki ROY Ishita DAS Minki MUNJAL Loganathan KARTHIK Gaurav KUMAR Sathish KUMAR Kokati Venkata Bhaskara RAO | 2014 | Frontiers in Biology2014，9，4： | 1 |
| 17 | Sonophotocatalytic degradation of monocrotophos using TiO2 and Fe^3+ 显示文摘 | Jagannathan Madhavan Panneer Selvam Sathish Kumar | 2010 | Journal of Hazardous Materials2010，177，13： | 1 |
| 18 | An Adaptive Security Model for Mobile Agents in Wireless Networks显示文摘 | Sathish P Alampalayam Anup Kumar | 2003 | IEEE2003，15，： | 1 |
| 19 | 1 D Modeling of AC Refrigerant Loop and Vehicle Cabin to Simulate Soak and Cool Down显示文摘 | Shankar Natarajan Sathish Kumar S Rieardo Amaral | 2013 | SAE Paper2013，，1： | 1 |
| 20 | P-Glycoprotein-and ~ytochrome P-450-mediated herbal drug interactions 显示文摘 | Kumar YS Adukondalu D Sathish D | 2010 | Drug Metabol Drug Interact2010，25，14： | 1 |
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