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| 1 | Hypoxia-mimicking 3D bioglass-nanoclay scaffolds promote endogenous bone regeneration显示文摘Large bone defect repair requires biomaterials that promote angiogenesis and osteogenesis.In present work,a nanoclay(Laponite,XLS)-functionalized 3D bioglass(BG)scaffold with hypoxia mimicking property was prepared by foam replication coupled with UV photopolymerization methods.Our data revealed that the incorporation of XLS can significantly promote the mechanical property of the scaffold and the osteogenic differentiation of human adipose mesenchymal stem cells(ADSCs)compared to the properties of the neat BG scaffold.Desferoxamine,a hypoxia mimicking agent,encourages bone regeneration via activating hypoxia-inducible factor-1 alpha(HIF-1α)-mediated angiogenesis.GelMA-DFO immobilization onto BG-XLS scaffold achieved sustained DFO release and inhibited DFO degradation.Furthermore,in vitro data demonstrated increased HIF-1αand vascular endothelial growth factor(VEGF)expressions on human adipose mesenchymal stem cells(ADSCs).Moreover,BG-XLS/GelMA-DFO scaffolds also significantly promoted the osteogenic differentiation of ADSCs.Most importantly,our in vivo data indicated BG-XLS/GelMA-DFO scaffolds strongly increased bone healing in a critical-sized mouse cranial bone defect model.Therefore,we developed a novel BG-XLS/GelMA-DFO scaffold which can not only induce the expression of VEGF,but also promote osteogenic differentiation of ADSCs to promote endogenous bone regeneration. | Xiao Zheng Xiaorong Zhang Yingting Wang Yangxi Liu Yining Pan Yijia Li Man Ji Xueqin Zhao Shengbin Huang Qingqing Yao | 2021 | Bioactive Materials2021，6，10： | 4 |
| 2 | Tracing of dye molecules in living plants through NaGdF_4:Yb^(3+),Er^(3+)fluorescent nanoprobes显示文摘In this paper, we demonstrated trace of dye molecules in living plants. The NaGdF4:Yb^(3+),Er^(3+) nanoparticles probe was used to detect the rhodamine B(RhB) in bean sprout. It is found that the fluorescencedye can be efficiently imbibed during the growing process and the absorbance presented a position dependence effect, which was supported by the upconversion spectra and the fluorescent image characterization. In addition, the concentration of the residual RhB in bean sprout can be efficiently traced by the synthesized probe based on the fluorescent resonant energy transfer. Finally, the relation between the excitation power, concentration and the ratio of yellow to green emission are discussed in detail. These results can be helpful in understanding the RhB dye molecules absorbance process in vegetable growth and provide an efficient way to trace the residual dyes in vivo plant. | Xiaofeng Wu Ya'nan Zhang Shiping Zhan Jin Li Guozheng Nie Shigang Hu Cong Yan Shaobing Wu Shengbin Cheng Junshan Hu Lichun Shi Yunxin Liu | 2019 | Journal of Rare Earths2019，37，3： | 3 |
| 3 | Correlation of the cyclin A expression level with porcine circovirus type 2 propagation efficiency显示文摘 | Qinghai Tang Shengbin Li Hui Zhang Yanwu Wei Hongli Wu Jianbo Liu Yiping Wang Dan Liu Zhihui Zhang Changming Liu | 2013 | Archives of Virology2013，，12： | 1 |
| 4 | MIR137 gene and target gene CACNA1C of miR-137 contribute to schizophrenia susceptibility in Han Chinese显示文摘 | Fanglin Guan Bo Zhang Tinglin Yan Lu Li Fei Liu Tao Li Zufei Feng Bao Zhang Xinshe Liu Shengbin Li | 2013 | Schizophrenia Research2013，，： | 1 |
| 5 | Extraction Process and Content Determination of Caffeic Acid in Laggera alata from Different Production Areas of Guangxi显示文摘[Objectives] To establish a method for determining the content of Laggera alata( D. Don) Sch. Bip. Ex Oliv. using caffeic acid the target component,and to compare the content of caffeic acid in the medicinal materials of L. alata in different production areas of Guangxi.[Methods]The content was determined by Inertsil~ODS-3 chromatographic column C_(18)( 4. 60 mm × 250 mm,5 μm,mobile phase: acetonitrile-0. 1% phosphoric acid( 22∶ 78),detection wavelength: 320 nm,flow rate: 1. 0 m L/min,column temperature: 30℃,and injection volume: 10 μL. [Results] The caffeic acid showed a good linear relationship in the range of injection volume of 0. 025 92-0. 259 2 μg( R =0. 999 5). The average recovery rate was 98. 33%( RSD = 1. 85%). L. alata in different production areas of Guangxi contained the caffeic acid,and there was a great difference in the caffeic acid. L. alata in Baise had the highest content of caffeic acid,while that in Guilin had the lowest content of caffeic acid. [Conclusions]This method can accurately determine the content of caffeic acid and is expected provide a scientific basis for the development and utilization of herbal medicine L. alata. | Jiangcun WEI Yong CHEN Zujie QIN Jiabao MA Shengbin CHEN Zuliang QUE Jinzhou LI Zijun CHEN | 2018 | Medicinal Plant2018，9，4： | 1 |
| 6 | X-chromosome STRs polymorphism of Han ethnic group from Northwest China显示文摘 | Bing Yu Hongbo Zhang Shengbin Li | 2005 | Forensic Sci Int2005，153，23： | 1 |
| 7 | Asymmetric Synthesis of Chiral a-Substituted Mercaptoglycine Derivatives via α-Sulfenylation of Ni(ll) Complex of Glycine and S-Substituted 4-Methylbenzenesulfonothioate显示文摘有代替 S 的 4-methylbenzenesulfonothioate 的 glycine 的 Ni (II ) 建筑群的不对称的 -sulfenylation 被报导。由于温和、简单的反应条件,这不对称的反应与各种各样的功能的组兼容。 | Jia Li Xiaohan Song Shengbin Zhou Jiang Wang Hong Liu | 2017 | Chinese Journal of Chemistry2017，35，9： | 1 |
| 8 | Investigation on some Schiff bases as HCl corrosioninhibitors for copper显示文摘 | Shulan Li Shenhao Chen Shengbin Lei Houyi Ma Rui Yu Dexin Liu | 1999 | Corrosion Science1999，，7： | 1 |
| 9 | Graphene- based polyaniline nanocomposites : preparation, properties and applications 显示文摘 | Wang Li Lu Xingping Lei Shengbin | 2014 | Journal of Materials Chemistry A2014，2，13： | 1 |
| 10 | Intercalibration of DMSP-OLS night-time light data by the invariant region method显示文摘 | Jiansheng Wu Shengbin He Jian Peng Weifeng Li Xiaohong Zhong | 2013 | International Journal of Remote Sensing2013，，20： | 1 |
| 11 | Inhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimer’s disease cybrid cell显示文摘 | Xueqi Gan Shengbin Huang Long Wu Yongfu Wang Gang Hu Guangyue Li Hongju Zhang Haiyang Yu Russell Howard Swerdlow John Xi Chen Shirley ShiDu Yan | 2014 | BBA - Molecular Basis of Disease2014，，2： | 1 |
| 12 | Development of in-situ Micro-Raman spectroscopy system for autoclave experimental apparatus显示文摘We developed a set of in-situ Micro-Raman spectroscopy system for autoclave experimental apparatus because of the scientific significance of in-situ Micro-Raman spectroscopy system under the high-pressure hydrothermal condition.We used this system to measure the Raman spectrum of water-fluid and quartz crystal at the temperature ranging from 125 to 420℃.The signal-tonoise ratio of the Raman signal is good. | Lin Chen Heping Li Shengbin Li Liping Xu Sen Lin Hongbin Zhou | 2020 | Acta Geochimica2020，39，4： | 0 |
| 13 | Latest progresses and the application of various electrolytes in high-performance solid-state lithium-sulfur batteries显示文摘With the emergence of some solid electrolytes(SSEs)with high ionic conductivity being comparable to liquid electrolytes,solid-state lithium-sulfur batteries(SSLSBs)have been widely regarded as one of the most promising candidates for the next generation of power generation energy storage batteries,and have been extensively researched.Though many fundamental and technological issues still need to be resolved to develop commercially viable technologies,SSLSBs using SSEs are expected to address the present limitations and achieve high energy and power density while improving safety,which is very attractive to large-scale energy storage systems.SSLSBs have been developed for many years.However,there are few systematic discussions related to the working mechanism of action of various electrolytes in SSLSBs and the defects and the corresponding solutions of various electrolytes.To fill this gap,it is very meaningful to review the recent progress of SSEs in SSLSBs.In this review,we comprehensively investigate and summarize the application of SSEs in LSBs to determine the differences which still exist between current progresses and real-world requirements,and comprehensively describe the mechanism of action of SSLSBs,including lithium-ion transport,interfacial contact,and catalytic conversion mechanisms.More importantly,the selection of solid electrolyte materials and the novel design of structures are reviewed and the properties of various SSEs are elucidated.Finally,the prospects and possible future research directions of SSLSBs including designing high electronic/ionic conductivity for cathodes,optimizing electrolytes and developing novel electrolytes with excellent properties,improving electrode/-electrolyte interface stability and enhancing interfacial dynamics between electrolyte and anode,using more advanced test equipment and characterization techniques to analyze conduction mechanism of Li^(+)in SSEs are presented.It is hoped that this review can arouse people’s attention and enlighten the development of functional materials and novel structures of SSEs in the next step. | Yanan Li Nanping Deng Hao Wang Qiang Zeng Shengbin Luo Yongbing Jin Quanxiang Li Weimin Kang Bowen Cheng | 2023 | Journal of Energy Chemistry2023，，7： | 0 |
| 14 | Development of a 100 MPa water–gas two-phase fluid pressurization device显示文摘This paper introduces a 100 MPa water gas twophase fluid pressurization device.The device can provide 100 MPa gas pressure and 200 MPa liquid pressure for small volume(<20 mL)high-pressure experimental devices.This device can make the pressure control independent of the temperature control without changing the material components of the system.The resolution of this device in adjusting the pressure is±0.2 MPa in the process of boosting and depressurizing.This pressure boosting device generates very little vibration during work and it can be used in experiments with strict requirements on vibration.As a thermodynamic parameter,pressure has a great influence on matter.In the field of experimental geochemistry,pressure is not only an experimental method and an extreme condition but an important physical parameter independent of temperature and chemical composition. | Shengbin Li Heping Li Lin Chen Hongbin Zhou | 2021 | Acta Geochimica2021，40，1： | 0 |
| 15 | LSDA-APF:A Local Obstacle Avoidance Algorithm for Unmanned Surface Vehicles Based on 5G Communication Environment显示文摘In view of the complex marine environment of navigation,especially in the case of multiple static and dynamic obstacles,the traditional obstacle avoidance algorithms applied to unmanned surface vehicles(USV)are prone to fall into the trap of local optimization.Therefore,this paper proposes an improved artificial potential field(APF)algorithm,which uses 5G communication technology to communicate between the USV and the control center.The algorithm introduces the USV discrimination mechanism to avoid the USV falling into local optimization when the USV encounter different obstacles in different scenarios.Considering the various scenarios between the USV and other dynamic obstacles such as vessels in the process of performing tasks,the algorithm introduces the concept of dynamic artificial potential field.For the multiple obstacles encountered in the process of USV sailing,based on the International Regulations for Preventing Collisions at Sea(COLREGS),the USV determines whether the next step will fall into local optimization through the discriminationmechanism.The local potential field of the USV will dynamically adjust,and the reverse virtual gravitational potential field will be added to prevent it from falling into the local optimization and avoid collisions.The objective function and cost function are designed at the same time,so that the USV can smoothly switch between the global path and the local obstacle avoidance.The simulation results show that the improved APF algorithm proposed in this paper can successfully avoid various obstacles in the complex marine environment,and take navigation time and economic cost into account. | Xiaoli Li Tongtong Jiao Jinfeng Ma Dongxing Duan Shengbin Liang | 2024 | Computer Modeling in Engineering & Sciences2024，138，1： | 0 |
| 16 | Mechanism of apoptosis induced by Mcl-1 inhibitor UMI-77 on gallbladder carcinoma GBC-SD cells显示文摘Objective:To investigate the mechanism of apoptosis induced by myeloid cell leukemia-1(Mcl-1)inhibitor UMI-77 on gallbladder carcinoma GBC-SD cells.Methods:GBC-SD cells were treated with different concentrations of UMI-77.GBC-SD cell proliferation and apoptosis were detected by MTT assay and Annexin V/PI.The expressions of Mcl-1,Bcl-2,Bcl-xL,Bax,Bak,cleaved-caspase 9,cleaved-caspase 3 and cleaved-PARP proteins in GBC-SD cells treated with UMI-77 were detected by Western blotting.Results:The results of MTT showed that different concentrations of UMI-77 had different inhibitory effects on cell proliferation of GBC-SD cells in a dose-dependent and time-dependent manner.Annexin V/PI results showed that the apoptosis rate was increasing gradually with the increase of UMI-77 concentration in a dose-dependent manner.Western blotting results showed that the expression of anti-apoptotic protein Mcl-1 was significantly decreased(p<0.05),and the expressions of Bax and Bak proteins were significantly increased respectively(p<0.05),but there were no significant changes in the expressions of Bcl-2 and Bcl-xL proteins,and the expression levels of cleaved-caspase 9,cleaved-caspase 3 and cleaved-PARP proteins were significantly increased(p<0.05)in 24 h after GBC-SD cells were treated with 10μmol/L of UMI-77.Conclusions:Mcl-1 inhibitor UMI-77 can induce the apoptosis of GBC-SD cells in a dose-dependent manner through the caspase-mediated endogenous apoptosis pathway.Therefore,Mcl-1 may become a new therapeutic target in the research on gallbladder cancer. | Shengbin Zhang Baoqin Liu Changcheng Dong Bing Li | 2019 | Discussion of Clinical Cases2019，6，1： | 0 |
| 17 | Two-dimensional covalent organic frameworks for electrocatalysis:Achievements,challenges,and opportunities显示文摘Covalent organic frameworks(COFs)represent an emerging class of crystalline porous polymers with high porosity,good stability,and adjustable structure,and their excellent characteristics lay a solid foundation for electrocatalysis.This review systematically introduces the design principles of the catalytic sites in two-dimensional(2D)COF-based electrocatalysts and analyzes the relationship between 2D COF structure and their electrocatalytic performances.In particular,the recent progress in the field of 2D COFs as electrocatalysts is comprehensively summarized.Finally,we discuss the current shortcomings and challenges on tailoring 2D COF for high-performance electrocatalysts in details,and look forward to promoting more researches on 2D COF-based electrocatalysts. | Ruoyu Zhao Teng Wang Junjun Li Yongxia Shi Man Hou Yong Yang Zhicheng Zhang Shengbin Lei | 2023 | Nano Research2023，16，7： | 0 |
| 18 | Construction and nanotribological study of a glassy covalent organic network on surface显示文摘Unraveling the nature of complex condensed matter systems is of paramount importance in a variety of fields such as pharmacology and materials science.Here we report the synthesis,by the dynamic covalent chemistry(DCC),of a robust,continuous,and low-defect glassy covalent organic network(GCON).The direct imaging of the molecular structure clearly shows the amorphous nature of GCONs,which consists with the competing(nano)crystallite model,not Zachariasen continuous random networks(Z-CRN).Remarkably,the microscopic friction properties were measured on GCONs by atomic force microscopy(AFM),and the GCONs showed lower friction force in comparison with crystalline covalent organic frameworks(COFs). | Guangyuan Feng Qingqing Luo Mengqi Li Yaru Song Yongtao Shen Shengbin Lei Wenping Hu | 2022 | Nano Research2022，15，5： | 0 |
| 19 | Highly interconnected macroporous MBG/PLGA scaffolds with enhanced mechanical and biological properties via green foaming strategy显示文摘In this study,mesoporous bioactive glass particles(MBGs) are incorporated into poly(lactic-co-glycolic acid)(PLGA) to fabricate highly interconnected macroporous composite scaffolds with enhanced mechanical and biological properties via a developed supercritical carbon dioxide(scCO_(2)) foaming method Scaffolds show favorable highly interconnected and macroporous structure through a high foaming pressure and long venting time foaming strategy.Specifically,scaffolds with porosity from 73% to 85%,pore size from 120 μm to 320 μm and interconnectivity of over 95% are controllably fabricated at MBG content from 0 wt% to 20 wt%.In comparison with neat PLGA scaffolds,composite scaffolds perform improved strength(up to 1.5 folds) and Young's modulus(up to 3 folds).The interconnected macroporous structure is beneficial to the ingrowth of cells.More importantly,composite scaffolds also provide a more promising microenvironment for cellular proliferation and adhesion with the release of bioactive ions.Hopefully,MBG/PLGA scaffolds developed by the green foaming strategy in this work show promising morphological,mechanical and biological features for tissue regeneration. | Chaobo Song Jiapeng Zhang Shuang Li Shengbin Yang Eryi Lu Zhenhao Xi Lian Cen Ling Zhao Weikang Yuan | 2021 | Chinese Journal of Chemical Engineering2021，34，1： | 0 |
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