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| 1 | Dendritic Cells Transduced with SOCS1 Gene Exhibit Regulatory DC Properties and Prolong Allograft Survival显示文摘SOCS1 is a key regulator of cytokine signaling and is important for maintaining balance in the immune system. It is thought to participate in negative feedback loops in cytokine signaling and may be an important signal for the regulation of dendritic cell (DC) maturation. However, it remains unclear whether DCs transduced with SOCS1 exhibit characteristics of regulatory DCs and induce allogeneic T-cell hyporesponsiveness. In this study, we constructed adenoviral vector coding SOCS1 (Ad-SOCS1) that can efficiently increase SOCS1 gene expression in bone marrow-derived dendritic cells. DCs transduced with Ad-SOCS1 (DC-SOCS1) expressed low levels of costimulatory and MHC molecules, were resistant to maturation and activation stimulation, induced allogeneic T-cell hyporesponsiveness, and promoted the generation of regulatory-like T cells in vitro. DC-SOCS1 pretreatment significantly prolonged the survival of allografts and led to a substantial increase in the generation of regulatory T cells. Our data suggest that SOCS1 inhibits DC maturation and induces regulatory DC generation, therefore possessing therapeutic potential to prevent rejection in organ transplantation. | Hong Fu Shaohua Song Fang Liu Zhijia Ni Xiaoyun Shen Liang Xiao Guoshan Ding Quanxing Wang | 2009 | Cellular & Molecular Immunology2009，6，2： | 20 |
| 2 | Efficient Gene Targeting in Zebrafish Mediated by a Zebrafish-Codon-Optimized Cas9 and Evaluation of Off-Targeting Effect显示文摘Targeted genome modifications with the Cas9/gRNA system derived from the clustered regularly interspaced short palindromic repeat/CRISPR-associated(CRISPR/Cas)system have been successfully used in cultured human cells as well as in most model organisms,including zebrafish(Danio rerio),mouse,and fruit fly(Chang et al.,2013;Cong et al.,2013; | Da Liu Zhanxiang Wang An Xiao Yutian Zhang Wenyuan Li Yao Zu Shaohua Yao Shuo Lin Bo Zhang | 2014 | Journal of Genetics and Genomics2014，41，1： | 18 |
| 3 | Characteristics and Source Identification of Polycyclic Aromatic Hydrocarbons (PAHs) in Urban Soils: A Review显示文摘Polycyclic aromatic hydrocarbons(PAHs) are mainly produced by combustion processes and consist of a number of toxic compounds.They are always emitted as a mixture and have become a major type of pollutants in urban areas.The degree of soil contamination by PAHs is of special concern in areas immediately in proximity to cities with heavy traffic,factories,older buildings,and infrastructure.The accumulation of soil PAHs is also affected by non-anthropogenic factors,such as climate,vegetation,and soil property.This paper reviews three typical source identification techniques,including diagnostic ratios,positive matrix factorization,and principle components analysis.The advantages or disadvantages of these techniques are analyzed.It is recommended that multiple identification techniques be used to determine the sources in order to minimize the weaknesses inherent in each method and thereby to strengthen the conclusions for PAH source identification. | WANG Chunhui WU Shaohua ZHOU Shenglu SHI Yaxing SONG Jing | 2017 | Pedosphere2017，27，1： | 18 |
| 4 | Silicon intensity Mach–Zehnder modulator for single lane 100 Gb/s applications显示文摘In this paper, a substrate removing technique in a silicon Mach–Zehnder modulator(MZM) is proposed and demonstrated to improve modulation bandwidth. Based on the novel and optimized traveling wave electrodes,the electrode transmission loss is reduced, and the electro-optical group index and 50 Ω impedance matching are improved, simultaneously. A 2 mm long substrate removed silicon MZM with the measured and extrapolated 3 dB electro-optical bandwidth of >50 GHz and 60 GHz at the-8 V bias voltage is designed and fabricated.Open optical eye diagrams of up to 90 GBaud∕s NRZ and 56 GBaud∕s four-level pulse amplitude modulation(PAM-4) are experimentally obtained without additional optical or digital compensations. Based on this silicon MZM, the performance in a short-reach transmission system is further investigated. Single-lane 112 Gb∕s and 128 Gb∕s transmissions over different distances of 1 km, 2 km, and 10 km are experimentally achieved based on this high-speed silicon MZM. | MIAOFENG LI LEI WANG XIANG LI XI XIAO AND SHAOHUA YU | 2018 | Photonics Research2018，6，2： | 18 |
| 5 | Types,Characteristics and Significances of Migrating Pathways of Gas-bearing Fluids in the Shenhu Area,Northern Continental Slope of the South China Sea显示文摘The first marine gas hydrate expedition in China has been conducted by Guangzhou Marine Geological Survey in the Shenhu Area, northern continental slope of the South China Sea. Previous study has analyzed the P-T conditions, geophysical anomalies and saturation calculations of these gas hydrates, but has not documented in detail the migration of gas-bearing fluids in the study area. Based on the interpretations of 2D/3D seismic data, this work identified two types of migration pathways for gas-bearing fluids in the Shenhu area, i.e., vertical and lateral pathways. The vertical pathways(largescale faults, gas chimneys and mud diapirs) presented as steep seismic reflection anomalies, which could be traced downward to the Eocene source rocks and may penetrate into the Late Miocene strata. The deeper gases/fluids might be allowed migrating into the shallower strata through these vertical conduits. However, the distributions showed distinct differences between these pathways. Large-scale faults developed only in the north and northeast of the Shenhu area, while in the drilling area gas chimneys were the sole vertical migration pathways. Since the Pliocene, normal faults, detachment faults and favorable sediments have constituted the lateral pathways in the Shenhu gas hydrate drilling area. Although these lateral pathways were connected with gas chimneys, they exerted different effects on hydrate formation and accumulation. Gas-bearing fluids migrated upward along gas chimneys might further migrate laterally because of the normal faults, thereby enlarging the range of the chimneys. Linking gas chimneys with the seafloor, the detachment faults might act as conduits for escaping gases/fluids. Re-deposited sediments developed at the early stage of the Quaternary were located within the gas hydrate stability zone, so hydrates would be enriched in these favorable sediments. Compared with the migration pathways(large-scale faults and mud diapirs) in the LW3-1 deep-sea oil/gas field, the migration efficiency of the vertical pathways(composed of gas chimneys) in the gas hydrate drilling area might be relatively low. Description and qualitative discrimination of migration pathways in the Shenhu gas hydrate drilling area are helpful to further understand the relationship between good-quality deep source rocks and shallow, mainly biogenicallyproduced, hydrates. As the main source rocks of the Baiyun sag, lacustrine mudstones in the Wenchang and Enping Formations may provide thermogenic methane. Gas chimneys with relatively low migration efficiency created the vertical pathways. Caused by the Dongsha tectonic movement, the release of overpressured fluids might reduce the vertical migration rates of the thermogenic methane. The thick bathyal/abyssal fine-grained sediments since the Late Miocene provided migration media with low permeability. These preconditions may cause carbon isotopic fractionation ofthermogenic methane during long-distance vertical migrations. Therefore, although geochemical analyses indicate that the methane forming gas hydrate in the Shenhu area was mainly produced biogenically, or was mixed methane primarily of microbial origin, thermogenic methane still contribute significantly. | SU Ming SHA Zhibin ZHANG Cuimei WANG Hongbin WU Nengyou YANG Rui LIANG Jinqiang QIAO Shaohua CONG Xiaorong LIU Jie | 2017 | Acta Geologica Sinica(English Edition)2017，91，1： | 16 |
| 6 | Modeling and optimal energy management of a power split hybrid electric vehicle显示文摘With the combination modes of engine and two electric machines,the power split device allows higher efficiency of the engine.The operation and of a power split HEV are analyzed,and the system dynamic model HEV is established event-driven for HEV forward system simulation dynamics controller design.Considering the mode,the fact the mode that the operation modes of is the are and the the is continuous theory.time-driven this for each structure selection of the controller built and the described finite with hybrid automaton control In control structure,process is depicted by the state mode machine(FSM).The multi-mode switch controller is designed to realize power distribution.Furthermore,vehicle operations programming are optimized,and finite the prediction nonlinear model horizon.predictive control(NMPC)strategy is applied by that implementing the dynamic(DP)and in the Comparative simulation The results optimal demonstrate strategy hybrid in control structure is effective feasible for HEV energy management design.NMPC is superior improving fuel economy. | SHI DeHua WANG ShaoHua Pierluigi Pisu CHEN Long WANG RuoChen WANG RenGuang | 2017 | Science China(Technological Sciences)2017，60，5： | 14 |
| 7 | Genome of Wild Mandarin and Domestication History of Mandarin显示文摘官员(柠檬 reticulata ) 是世界范围的最重要的柠檬庄稼之一。它的驯服被相信发生在华南,它是四几千年的官员耕作的中心之一。我们在 Nanling 区域附近收集了官员的自然野人口并且在附近栽培了 landraces。我们发现柠檬性的酸水平戏剧性地在栽培官员被减少。理解 ? 官员驯服的基因基础,我们 de novo 装配了野官员的一个草稿染色体并且分析了一套 104 个柠檬染色体。我们发现 Mangshan 官员是一种原始类型并且二个独立驯服事件发生了,分别地导致在北方和南方 Nanling 山的二组栽培官员(MD1 和 MD2 ) 。二个瓶颈和有效人口尺寸的二扩大为栽培官员的 MD1 组被识别。然而,在 MD2 组织 ? 在人口尺寸有长、连续的减少。MD1 和 MD2 官员从栽培 pummelo 种类显示出种间的基因渗入的不同模式。我们在官员的驯服期间在选择下面可能在基因在柠檬酸盐内容的规定包含了的 aconitate hydratase (ACO ) 识别了高分叉的一个区域,它是。这研究为现存野官员人口的地理起源提供具体基因证据并且使驯服和官员的进化历史清楚些。 | Lun Wang Fa He Yue Huang Jiaxian He Shuizhi Yang Jiwu Zeng Chongling Deng Xiaolin Jiang Yiwen Fang Shaohua Wen Rangwei Xu Huiwen Yu Xiaoming Yang Guangyan Zhong Chuanwu Chen Xiang Yan Changfu Zhou Hongyan Zhang Zongzhou Xie Robert M. Larkin Xiuxin Deng Qiang Xu | 2018 | Molecular Plant2018，11，8： | 14 |
| 8 | BMP2 and VEGF promote angiogenesis but retard terminal differentiation of osteoblasts in bone regeneration by up-regulating Idl显示文摘不适当的 vascularization 限制骨头缺点的修理。以便改进 angiogenesis 并且加速成骨,有在骨头新生的基因修正的 co 有教养的房间的协同在这研究被调查。Endothelial 祖先房间(EPC ) 和骨头髓干细胞(BMSC ) 是有脉管的 endothelial 生长因素(VEGF ) 和骨头的基因的 transfected 形态基因的蛋白质 2 (BMP2 ) 由侵入人体气管粘膜的病菌分别地。co 有教养的房间,包括 BMSC + EPC, Ad-BMP2BMSC + EPC, BMSC + Ad-VEGFEPC,和 Ad-BMP2BMSC + 指定 Ad-VEGFEPC 组织为四个组,在 alginate 胶化上被播种然后肌内地植入进老鼠在 angiogenesis 和成骨上评估效果。VEGF 和 BMP2 能导致禁止者的 overexpression DNA 有约束力 1 (Id1 ) 显著地在 vitro 和增加支持了试管形成的基因在在培植以后的 Ad-BMP2BMSC + Ad-VEGFEPC 组的血容器的数量。不过, Id1 的 overexpression 延迟了造骨细胞和骨头形成的终端区别。后来,在 transcriptional 水平,钙小瘤,和碱的磷酸酶(高山) 活动的 osteogenic 基因表示证明渐渐的减少和最新形成的成骨区域的数量在 Ad-BMP2BMSC + Ad-VEGFEPC 组展出了小增加。这发现建议在 VEGFEPC 和 BMP2BMSCs 的 Id1 表示的一条平衡规定可能对为骨头新生的基于房间、基于基因的途径批评。 | Xiaobin Song Shaohua Liu Xun Qu Yingwei Hu Xiaoying Zhang Tao Wang Fengcai Wei | 2011 | Acta Biochimica et Biophysica Sinica2011，43，10： | 13 |
| 9 | Genome-wide Identification and Classification of HSF Family in Grape, and Their Transcriptional Analysis under Heat Acclimation and Heat Stress显示文摘Heat stress is one of the most serious threats in viticulture. Heat shock transcription factors(HSFs) have been proven to be the most important transcriptional factor family in the plant response to heat. In this study, a total of 19 putative HSF genes(VHSFs) were identified from the 12 × Vitis vinifera Pinot Noir PN4002 genome, and their chromosomal location, phylogenetic tree, exon-intron structure and conserved motifs were also analyzed. In addition, these HSFs transcriptional profiles in Vitis vinifera 'Jingxiu'(weak heat tolerance) and Vitis davidii 'Tangwei'(strong heat tolerance) under heat stress(47℃) and heat acclimation(38℃) were presented. Only VHSF01, VHSF05, VHSF15 and VHSF18 among 19 VHSFs showed different transcriptional models in these two genotypes under the same treatment, suggesting that these four VHSFs may be important factors which result in a thermotolerance difference between 'Jingxiu' and 'Tangwei'. This study provides novel insights into the response of 19 VHSFs to heat stress in the grape and suggests that potential key VHSFs in grape thermotolerance have great implications for molecular breeding in grapes. | LIU Guotian CHAI Fengmei WANG Yi JIANG Jinzhu DUAN Wei WANG Yuting WANG Fangfang LI Shaohua WANG Lijun | 2018 | Horticultural Plant Journal2018，4，4： | 13 |
| 10 | Effects of culm carbohydrate partitioning on basal stem strength in a high-yielding rice population显示文摘Rice culm carbohydrate transport can simultaneously affect grain filling and stem lodging resistance by regulating non-structural carbohydrate(NSC) and structural carbohydrate(SC) contents. However, the relationship between carbohydrate transposition and culm strength is not well documented. Accordingly, a high-yielding hybrid rice cultivar(Y Liangyou 2) was tested under different N fertilization regimes at two locations, Taoyuan(a special high-yield eco-site), Yunnan province and Danyang(a representative eco-site of the middle and lower Yangtze), Jiangsu province, China. Significantly higher grain yield and basal stem strength were found at Taoyuan than Danyang under all N rates throughout the two-year experiment. At heading stage, soluble sugars, starch, cellulose and lignin contents of the basal culm at Taoyuan were significantly 132.0%, 73.7%, 1.2%, and 62.7% higher than those at Danyang, respectively. At 20 days after heading, soluble sugars and starch content at Taoyuan decreased significantly compared to Danyang, but lignin content remained higher. Culm carbohydrate transport to kernels at Taoyuan was significantly greater than that at Danyang, and the proportion of soluble sugars and starch was correspondingly 62.9%lower. However, the proportion of lignin and cellulose was 22.7% higher at Taoyuan than that at Danyang. Soluble sugars and starch partitioning were significantly reduced under an increased nitrogen application rate, but SC partitioning was little affected. There were significant positive correlations between basal culm bending stress and dry weight and cellulose and lignin proportions at both locations under all N rates, suggesting that the higher SC proportion at 20 days after heading was primarily responsible for culm strength.These results suggest that high-yielding rice populations with greater culm strength require both moderate NSC transport and greater SC accumulation. | Jun Zhang Ganghua Li Qingyu Huang Zhenghui Liu Chengqiang Ding She Tang Lin Chen Shaohua Wang Yanfeng Ding Weijian Zhang | 2017 | The Crop Journal2017，5，6： | 13 |
| 11 | Field investigations of high stress soft surrounding rocks and deformation control显示文摘Field investigations of high stress soft rock deformations show that the high stress soft rock roadway can slide with large deformation. Severe extrusion and floor heave can also be subsequently observed. The supported roadway can be locally damaged or completely fail, where the floor has a large deformation and/or is seriously damaged. The factors inducing large deformation of surrounding rocks in deep roadway are rock strengths, structure face cutting types, stress states, stress release, support patterns,and construction methods. Based on the deformation characteristics of high stress soft rock roadway, a comprehensive support scheme is proposed. The overall support technology of 'step-by-step and joint,hierarchical reinforcement' for roadway is presented, and the anchor cable and bolt parameters to check the design methods are also given. Finally, the proposed comprehensive support method 'bolt t metal mesh t U-steel arch t shortcrete t grouting and cable' is used in the extension section of east main haulage roadway at 850 m level of Qujiang coal mine. The 173-day monitoring results show that the average convergence of sidewalls reaches 208 mm, and the average relative convergence of roof and floor reaches 448 mm, suggesting that this kind of support technology for controlling large deformation of high stress soft surrounding rock roadway is effective. | Weijian Yu Weijun Wang Xinyuan Chen Shaohua Du | 2015 | Journal of Rock Mechanics and Geotechnical Engineering2015，7，4： | 12 |
| 12 | Microstructure and mechanical properties of forged Al-7.1Zn-1.1Mg-1.6Cu-0.14Zr alloy after two-step ageing treatment at 120 and 170℃显示文摘The tensile properties,electrical conductivity,and microstructure of the forged Al-7.1Zn-1.1Mg-1.6Cu-0.14Zr alloy were investigated after a two-step ageing treatment at 120 and 170℃.The results indicate that the strength of the alloy reaches the peak value at 170℃ for 1 h during the second step ageing and then decreases sharply.However,the electrical conductivity value increases continuously with the second ageing time increasing.The fracture mechanism of the alloy is intergranular fracture for 1 h and then changes to dimple transgranular fracture later,and the toughness of the alloy is improved significantly.The phases of η' and η are major precipitates in the alloy under the two-step ageing condition.Discontinuous grain boundary precipitates and precipitate-free zones along the grain boundary are clearly observed. | WANG Shaohua ZHANG Xingguo YANG Shoujie FANG Canfeng HAO Hai DAI Shenglong | 2010 | Rare Metals2010，29，4： | 12 |
| 13 | Onco-miR-24 regulates cell growth and apoptosis by targeting BCL2L11 in gastric cancer显示文摘胃的癌症是世界范围的最普通的恶意之一;然而,在 tumorigenesis 的分子的机制仍然需要探索。BCL2L11 属于 BCL-2 家庭,并且充当内在的 apoptotic 串联的一个中央管理者并且调停房间 apoptosis。尽管 miRNAs 被报导了涉及癌症开发的每个阶段,在 GC 的 miR-24 的角色还没被报导。在现在的学习,当 BCL2L11 的表示在 GC 的肿瘤纸巾被禁止时, miR-24 被发现起来调整。研究从在 vitro 并且在显示出的 vivo,那 miR-24 调整 BCL2L11 表示由与 mRNA 的 3UTR 直接有约束力,因此支持房间生长,移植当禁止房间 apoptosis 时。因此, miR-24 是能是为未来的潜在的药目标的新奇 onco-miRNA 临床的使用。 | Haiyang Zhang Jingjing Duan Yanjun Qu Ting Deng Rui Liu Le Zhang Ming Bai Jialu Li Tao Ning Shaohua Ge Xia Wang ZhenzhenWang~ Qian Fan Hongli Li Guoguang Ying Dingzhi Huang Yi Ba | 2016 | Protein & Cell2016，7，2： | 11 |
| 14 | Methane emissions from rice fields under continuous straw return in the middle-lower reaches of the Yangtze River显示文摘A three-year experiment was conducted in the middle-lower reaches of the Yangtze River in China to study the influence of continuous wheat straw return during the rice season and continuous rice straw return in wheat on methane (CH 4 ) emissions from rice fields in which, the rice-wheat rotation system is the most dominant planting pattern. The field experiment was initiated in October 2009 and has continued since the wheat-growing season of that year. The analyses for the present study were conducted in the second (2011) and third (2012) rice growing seasons. Four treatments, namely, the continuous return of wheat straw and rice straw in every season (WR), of rice straw but no wheat straw return (R), of wheat straw but no rice straw return (W) and a control with no straw return (CK), were laid out in a randomized split-plot design. The total seasonal CH 4 emissions ranged from 107.4 to 491.7 kg/ha (2011) and 160.3 to 909.6 kg/ha (2012). The increase in CH 4 emissions for treatments WR and W were 289% and 230% in the second year and 185% and 225% in the third year, respectively, in relation to CK. We observed less methane emissions in the treatment R than in CK by 14%-43%, but not statistically significant. Treatment R could increase rice productivity while no more CH 4 emission occurs. The difference in the total CH 4 emissions mainly related to a difference in the methane flux rate during the first 30-35 days after transplant in the rice growing season, which was caused by the amount of dissolved oxygen in paddy water and the amount of reducible soil materials. | Pengfu Hou Ganghua Li Shaohua Wang Xin Jin Yiming Yang Xiaoting Chen Chengqiang Ding Zhenghui Liu Yanfeng Ding | 2013 | Journal of Environmental Sciences2013，25，9： | 10 |
| 15 | Vehicle height control of electronic air suspension system based on mixed logical dynamical modelling显示文摘Due to the coexistence and coupling of continuous variables and discrete events, the vehicle height adjustment process of electronic air suspension system can be regarded as a typical hybrid system. Therefore, the hybrid system theory was applied to design a novel vehicle height control strategy in this paper. A nonlinear mechanism model of the vehicle height adjustment system was established based on vehicle system dynamics and thermodynamic theory for variable-mass gas charge/discharge system. In order to model both the continuous/discrete dynamics of vehicle height adjustment process and the on-off statuses switching of solenoid valves, the framework of mixed logical dynamical(MLD) modelling was used. On the basis of the vehicle height adjustment control strategy, the MLD model of the adjustment process was built by introducing auxiliary logical variables and auxiliary continuous variables. Then, the co-simulation of the nonlinear mechanism model and the MLD model was conducted based on the compiling of HYSDEL. The simulation and experimental results show that the proposed control strategy can not only adjust the vehicle height effectively, but also achieve the on-off statuses direct control of solenoid valves. | SUN XiaoQiang CHEN Long WANG ShaoHua XU Xing | 2015 | Science China(Technological Sciences)2015，58，11： | 10 |
| 16 | Ferrites boosting photocatalytic hydrogen evolution over graphitic carbon nitride: a case study of(Co, Ni)Fe_2O_4 modification显示文摘The charge carrier separation and surface catalytic redox reactions are of primary importance as elementary steps in photocatalytic hydrogen evolution. In this study, both of these two processes in photocatalytic hydrogen evolution over graphitic carbon nitride(g-C_3N_4) were greatly promoted with the earth-abundant ferrites(Co,Ni)Fe_2O_4modification. Co Fe_2O_4 was further demonstrated to be a better modifier for g-C_3N_4 as compared to Ni Fe_2O_4,due to the more efficient charge carrier transfer as well as superior surface oxidative catalytic activity. When together loading Co Fe_2O_4 and reductive hydrogen production electrocatalyst Pt onto g-C_3N_4, the obtained Pt/g-C_3N_4/Co Fe_2O_4 photocatalyst achieved visible-light(λ>420 nm) hydrogen production rate 3.5 times as high as Pt/g-C_3N_4, with the apparent quantum yield reaching 3.35 % at 420 nm. | Jie Chen Daming Zhao Zhidan Diao Miao Wang Shaohua Shen | 2016 | Science Bulletin2016，61，4： | 10 |
| 17 | Fate of Basal N Under Split Fertilization in Rice with ^(15)N Isotope Tracer显示文摘Split fertilization strategy is popularly adopted in rice to synchronize soil nitrogen(N) supply and crop N demand. Attention has been paid more on mid-season topdressing N, but limited on basal N. A clearer understanding of the basal N fate under split fertilization is crucial for determining rational basal N split ratio to improve the yield and reduce the loss to environment. A two-year field experiment with two N rates of 150 and 300 kg Nha^(-1), two split ratios of basal N, 40% and 25%, and two rice varieties,Wuyunjing 23(japonica) and Y-liangyou 2(super hybrid indica), was conducted. Labelled ^(15) N urea was supplied in micro-plots as basal fertilizer to determine the plant uptake, translocation, soil residual, and loss of basal N fertilizer. The results showed that basal N absorbed by rice was only 1.6%–11.5% before tillering fertilization(8–10 d after transplanting), 6.5%–21.4% from tillering fertilization to panicle fertilization, and little(0.1%–4.4%) after panicle fertilization. The recovery efficiency of basal N for the entire rice growth stage was low and ranged from 18.7% to 24.8%, not significantly affected by cultivars or N treatments. Soil residual basal N accounted for 10.3%–36.4% and decreased with increasing total N rate and basal N ratio, regardless of variety and year. 43.8%–70.4% of basal N was lost into the environment based on the N balance. Basal N loss was significantly linearly positive related with the basal N rate and obviously enhanced by the increasing basal N ratio for both varieties in both 2012 and 2013. The N use efficiency and yield was significantly improved when decreasing the basal N ratio from 40% to 25%. The results indicated that the basal N ratio should be reduced, especially with limited N inputs, to improve the yield and reduce the N loss to the environment. | LI Ganghua LIN Jingjing XUE Lihong DING Yanfeng WANG Shaohua YANG Linzhang | 2018 | Pedosphere2018，28，1： | 9 |
| 18 | Activating ZnO nanorod photoanodes in visible light by Cu ion implantation显示文摘 | Meng Wang Feng Ren Guangxu Cai Yichao Liu Shaohua Shen Liejin Guo | 2014 | Nano Research2014，7，3： | 9 |
| 19 | Periodontitis may induce gut microbiota dysbiosis via salivary microbiota显示文摘The aim of this study was to identify whether periodontitis induces gut microbiota dysbiosis via invasion by salivary microbes.First,faecal and salivary samples were collected from periodontally healthy participants(PH group,n=16)and patients with severe periodontitis(SP group,n=21)and analysed by 16S ribosomal RNA sequencing.Significant differences were observed in both the faecal and salivary microbiota between the PH and SP groups.Notably,more saliva-sourced microbes were observed in the faecal samples of the SP group.Then,the remaining salivary microbes were transplanted into C57BL6/J mice(the C-PH group and the C-SP group),and it was found that the composition of the gut microbiota of the C-SP group was significantly different from that of the C-PH group,with Porphyromonadaceae and Fusobacterium being significantly enriched in the C-SP group.In the colon,the C-SP group showed significantly reduced crypt depth and zonula occludens-1 expression.The m RNA expression levels of pro-inflammatory cytokines,chemokines and tight junction proteins were significantly higher in the C-SP group.To further investigate whether salivary bacteria could persist in the intestine,the salivary microbiota was stained with carboxyfluorescein diacetate succinimidyl ester and transplanted into mice.We found that salivary microbes from both the PH group and the SP group could persist in the gut for at least 24 h.Thus,our data demonstrate that periodontitis may induce gut microbiota dysbiosis through the influx of salivary microbes. | Jun Bao Lili Li Yangheng Zhang Min Wang Faming Chen Shaohua Ge Bin Chen Fuhua Yan | 2022 | International Journal of Oral Science2022，14，3： | 9 |
| 20 | Dynamic tensile behaviour and crack propagation of coal under coupled static-dynamic loading显示文摘The fracture behaviour and crack propagation features of coal under coupled static-dynamic loading conditions are important when evaluating the dynamic failure of coal.In this study,coupled static-dynamic loading tests are conducted on Brazilian disc(BD)coal specimens using a modified split Hopkinson pressure bar(SHPB).The effects of the static axial pre-stress and loading rate on the dynamic tensile strength and crack propagation characteristics of BD coal specimens are studied.The average dynamic indirect tensile strength of coal specimens increases first and then decreases with the static axial pre-stress increasing.When no static axial pre-stress is applied,or the static axial pre-stress is 30%of the static tensile strength,the dynamic indirect tensile strength of coal specimens shows an increase trend as the loading rate increases.When the static axial pre-stress is 60%of the static tensile strength,the dynamic indirect tensile strength shows a fluctuant trend as the loading rate increases.According to the crack propagation process of coal specimens recorded by high-speed camera,the impact velocity influences the mode of crack propagation,while the static axial pre-stress influences the direction of crack propagation.The failure of coal specimens is a coupled tensile-shear failure under high impact velocity.When there is no static axial pre-stress,tensile cracks occur in the vertical loading direction.When the static axial pre-stress is applied,the number of cracks perpendicular to the loading direction decreases,and more cracks occur in the parallel loading direction. | Xianjie Hao Weisheng Du Yixin Zhao Zhuowen Sun Qian Zhang Shaohua Wang Haiqing Qiao | 2020 | International Journal of Mining Science and Technology2020，30，5： | 8 |
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