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| 1 | The Association of Maternal Body Composition and Dietary Intake with the Risk of Gestational Diabetes Mellitus during the Second Trimester in a Cohort of Chinese Pregnant Women显示文摘Objective To investigate the association of maternal body composition and dietary intake with the risk of gestational diabetes mellitus(GDM). Methods A total 154 GDM subjects and 981 controls were enrolled in a prospective cohort study in 11 hospitals from May 20, 2012 to December 31, 2013. Bioelectrical impedance analysis and dietary surveys were used to determine body composition and to evaluate the intake of nutrients in subjects at 21-24 weeks' gestation(WG). Logistic regression analysis was applied to explore the relationships of maternal body composition and dietary intake with the risk of GDM morbidity. Results Age, pre-pregnant body weight(BW), and body mass index(BMI) were associated with increased risk of GDM. Fat mass(FM), fat mass percentage(FMP), extracellular water(ECW), BMI, BW, energy, protein, fat, and carbohydrates at 21-24 WG were associated with an increased risk of GDM. In contrast, fat free mass(FFM), muscular mass(MM), and intracellular water(ICW) were associated with a decreased risk of GDM. Conclusion Maternal body composition and dietary intake during the second trimester of pregnancy were associated with the risk of GDM morbidity. | Xu Qing Gao Zhi Ying Li Li Ming Wang Lu Zhang Qian Teng Yue Zhao Xia Ge Sheng Jing Hong Jiang Yang Yong Tao Liu Xiao Jun Lyu Chun Jian Mao Lun Yu Xiao Ming Liu Ying Hua Kong Ai Jing Yang Xue Yan Liu Zhao Zhang Yong Wang Jin Zhang Xin Sheng Xue Chang Yong Lu Yan Ping | 2016 | Biomedical and Environmental Sciences2016，29，1： | 29 |
| 2 | A Review on Metal-Organic Framework-Derived Porous Carbon-Based Novel Microwave Absorption Materials显示文摘The development of microwave absorption materials(MAMs) is a considerable important topic because our living space is crowed with electromagnetic wave which threatens human’s health.And MAMs are also used in radar stealth for protecting the weapons from being detected.Many nanomaterials were studied as MAMs,but not all of them have the satisfactory performance.Recently,metal-organic frameworks(MOFs) have attracted tremendous attention owing to their tunable chemical structures,diverse properties,large specific surface area and uniform pore distribution.MOF can transform to porous carbon(PC) which is decorated with metal species at appropriate pyrolysis temperature.However,the loss mechanism of pure MOF-derived PC is often relatively simple.In order to further improve the MA performance,the MOFs coupled with other loss materials are a widely studied method.In this review,we summarize the theories of MA,the progress of different MOF-derived PC-based MAMs,tunable chemical structures incorporated with dielectric loss or magnetic loss materials.The different MA performance and mechanisms are discussed in detail.Finally,the shortcomings,challenges and perspectives of MOF-derived PC-based MAMs are also presented.We hope this review could provide a new insight to design and fabricate MOF-derived PC-based MAMs with better fundamental understanding and practical application. | Zhiwei Zhang Zhihao Cai Ziyuan Wang Yaling Peng Lun Xia Suping Ma Zhanzhao Yin Yi Huang | 2021 | Nano-Micro Letters2021，13，4： | 17 |
| 3 | Genome of Wild Mandarin and Domestication History of Mandarin显示文摘官员(柠檬 reticulata ) 是世界范围的最重要的柠檬庄稼之一。它的驯服被相信发生在华南,它是四几千年的官员耕作的中心之一。我们在 Nanling 区域附近收集了官员的自然野人口并且在附近栽培了 landraces。我们发现柠檬性的酸水平戏剧性地在栽培官员被减少。理解 ? 官员驯服的基因基础,我们 de novo 装配了野官员的一个草稿染色体并且分析了一套 104 个柠檬染色体。我们发现 Mangshan 官员是一种原始类型并且二个独立驯服事件发生了,分别地导致在北方和南方 Nanling 山的二组栽培官员(MD1 和 MD2 ) 。二个瓶颈和有效人口尺寸的二扩大为栽培官员的 MD1 组被识别。然而,在 MD2 组织 ? 在人口尺寸有长、连续的减少。MD1 和 MD2 官员从栽培 pummelo 种类显示出种间的基因渗入的不同模式。我们在官员的驯服期间在选择下面可能在基因在柠檬酸盐内容的规定包含了的 aconitate hydratase (ACO ) 识别了高分叉的一个区域,它是。这研究为现存野官员人口的地理起源提供具体基因证据并且使驯服和官员的进化历史清楚些。 | Lun Wang Fa He Yue Huang Jiaxian He Shuizhi Yang Jiwu Zeng Chongling Deng Xiaolin Jiang Yiwen Fang Shaohua Wen Rangwei Xu Huiwen Yu Xiaoming Yang Guangyan Zhong Chuanwu Chen Xiang Yan Changfu Zhou Hongyan Zhang Zongzhou Xie Robert M. Larkin Xiuxin Deng Qiang Xu | 2018 | Molecular Plant2018，11，8： | 14 |
| 4 | Efficacy of Leflunomide, Telmisartan, and Clopidogrel for Immunoglobulin A Nephropathy: A Randomized Controlled Trial显示文摘 | Jie Wu Shu-Wei Duan Xue-Feng Sun Wen-Ge Li Ya-Ping Wang Wen-Hu Liu Jian-Rong Zhang Li-De Lun Xue-Mei Li Chun-Hua Zhou Ji-Jun Li Shu-Wen Liu Yuan-Sheng Xie Guang-Yan Cai Lu Ma Wen Huang Hua Wu Qiang Jia Xiang-Mei Chen | 2016 | Chinese Medical Journal2016，，16： | 13 |
| 5 | Numerical study on ULF waves in a dipole field excited by sudden impulse显示文摘A three-dimensional numerical model is employed to investigate ULF waves ex-cited by the sudden impulse (SI) of the solar wind dynamic pressure interacting with a dipole magnetosphere. We focus on the solar wind-magnetosphere energy coupling through ULF waves, and the influences of the SI spectrum on the cavity mode structure and the energy deposition due to field line resonances (FLRs) in the magnetosphere. The numerical results show that for a given SI lasting for 1 min with amplitude of 50 mV/m impinging on the subsolar magnetopause, the total ULF energy transported from the solar wind to the magnetosphere is about the magni-tude of 1014 J. The efficiency of the solar wind energy input is around 1%, which depends little on the location of the magnetopause in the model. It is also found that the energy of the cavity mode is confined in the region near the magnetopause, whereas, the energy of the toroidal mode may be distributed among a few specific L-shells. With a given size of the model magnetosphere and plasma density distri-bution, it is shown that the fundamental eigenfrequency of the cavity mode and the central locations of the FLRs do not vary noticeably with the power spectrum of the SI. It is worth noting that the spectrum of the SI affects the excitation of higher harmonics of the global cavity mode. The broader the bandwidth of the SI is, the higher harmonics of cavity mode could be excited. Meanwhile, the corresponding FLRs regions are broadened at the same time, which implies that the global cavity modes and toroidal modes can resonate on more magnetic L-shells when more harmonics of the global cavity modes appear. | YANG Biao FU SuiYan ZONG QiuGang WANG YongFu ZHOU XuZhi PU ZuYin XIE Lun | 2008 | Science China(Technological Sciences)2008，51，10： | 12 |
| 6 | Geochemical characteristics and genetic model of dolomite reservoirs in the eastern margin of the Pre-Caspian Basin显示文摘The widespread Carboniferous KT-I dolomite in the eastern margin of the Pre-Caspian Basin is an important hydrocarbon reservoir. The dolomite lithology is dominated by crystalline dolomite. The δ18O values range from -6.71‰ to 2.45‰, and average 0.063‰, obviously larger than -2.5‰, indicating low-temperature dolomite of evaporation origin. Stable strontium isotope ratios (87Sr/86Sr) range from 0.70829 to 0.70875 and average 0.708365, very consistent with 87Sr/86Sr ratios in Carboniferous seawater. Chemical analysis of Ca and Mg elements shows that the dolomite has 9.1 mole% excess Ca or even higher before stabilization. The degree of order of dolomite is medium-slightly poor, varying in a range of 0.336-0.504 and averaging 0.417. It suggests that the dolomite formed under near-surface conditions. There are two models for the origin of the Carboniferous KT-I dolomite reservoir. These are 1) the evaporation concentration - weathering crust model and 2) the shoal facies - seepage reflux model. The former is mainly developed in restricted platforms - evaporate platforms of restricted marine deposition environments with a representation of dolomite associated with gypsum and mudstone. The latter mainly formed in platform edge shoals and intra-platform shoals and is controlled by dolomitization due to high salinity sea water influx from adjacent restricted sea or evaporate platform. | Wang Shuqin Zhao Lun Cheng Xubin Fan Zifei He Ling | 2012 | Petroleum Science2012，9，2： | 12 |
| 7 | Multi-spacecraft observations of ULF waves during the recovery phase of magnetic storm on October 30, 2003显示文摘Based on observations obtained by Cluster C1, GOES 10, 12, and Polar, the global ULF wave properties are studied during the recovery phase of a very intense magnetic storm-Halloween storm (October 31, 2003, 21:00-23:00 UT). The results indicate that the ULF waves’ properties observed by different satellites, such as amplitude, period, etc. show large variations. This can be interpreted as that Field Line Resonance (FLR) might take place in the region where Cluster C1 passed. The compressional wave of the cavity mode coupled with FLR’s shear Alfven wave and fed energy to the latter, forming a large-amplitude toroidal mode. From the point of period, Cluster C1 observed the shortest period, GOES 10, 12 observed the middle, while Polar observed the longest. The wave period of toroidal mode observed by Cluster C1 kept almost unchanging when Cluster C1 passed L range from 11.7 to 5.3. Using the Squared Wavelet Coherence analysis method, we estimated that the FLR region in the dayside magnetosphere could expand to at least 4 local time widths. The toroidal mode observed by Polar was a standing wave, while the pol-oidal mode was a propagating wave, the observation results could be well ex-plained by the waveguide mode theory. Since the solarwind speed Vx was -800 km/s and the dynamic pressure varied little, we speculated that the source of the ULF wave was the Kelvin-Helmholtz instability at the magnetopause triggered by high speed solarwind. | YongFu Wang SuiYan Fu QiuGang Zong Biao Yang ZuYin Pu Lun Xie XuZhi Zhou | 2008 | Science China(Technological Sciences)2008，51，10： | 11 |
| 8 | Temperature variability since A.D.1837 inferred from tree-ring maximum density of Abies fabri on Gongga Mountain,China显示文摘Two tree-ring MXD (maximum latewood density) chronologies of Abies fabri were developed from the eastern slopes of Gongga Mountain, and a regional chronology (RC) was established based on the two MXD chronologies. There were significant positive correlations between the three MXD chronologies and August-September temperature, and the RC had the highest correlation (r=0.733, n=48, P<0.001) with mean August-September temperature. Based on growth-climate analyses, we reconstructed mean August-September temperature during the past 171 years for the study area. The reconstruction explained 53.5% of the instrumental temperature variance during the period 1960-2007 (F=52.8, R2adj =52.4%). In the past 171 years, there were 22 very warm years and 23 very cold years, four cold periods (1837-1842, 1884-1891, 1899-1905 and 1984-1989) and three warm periods (1966-1973, 1916-1924 and 1876-1881). Our reconstruction was validated by other tree ring-based temperature reconstructions from the surrounding area and documented climate disaster events. | DUAN JianPing WANG Lily LI Lun CHEN KeLong | 2010 | Chinese Science Bulletin2010，55，26： | 11 |
| 9 | Application of biochar-based materials in environmental remediation:from multi-level structures to specific devices显示文摘The development of biochar has triggered a hot-spot in various research fields including agriculture,energy,environment,and materials.Biochar-based materials provide a novel approach against environmental challenging issues.Considering the rapid development of biochar materials,this review serves as a valuable platform to summarize the recent progress on the theoretical investigation and engineering applications of biochar materials in environmental remediation.For a better understanding of the structure-application relationships,the structural properties of biochar from macroscopic and microscopic aspects are summarized.The multilevel structures including elements,phases,surface chemistry,and molecular are highlighted to elucidate the multi-functional properties of biochars.Sorption,catalysis,redox reaction,and biological activity of biochar are briefly illustrated,which influence the transport,transformation,and removal of organic and inorganic pollutants in the environments.According to the multi-level structures and structure-application relationships of biochar,specific biochar-based materials and devices have been designed for practical environmental application.The important progress on the functionalization and device of biochar-based materials,including magnetic biochars,2D and 3D biochar-based macrostructures,immobilized microorganism on biochar,and biochar-amended biofilters are highlighted.The environmental friendliness and sustainability of biochar-based materials,considering the whole cycle from synthesis to application,are evaluated. | Lun Lu Wentao Yu Yaofeng Wang Kun Zhang Xiaomin Zhu Yuecan Zhang Yajing Wu Habib Ullah Xin Xiao Baoliang Chen | 2020 | Biochar2020，2，1： | 11 |
| 10 | Efficacy and safety of the long-acting fusion inhibitor albuvirtide in antiretroviral-experienced adults with human immunodeficiency virus-1:interim analysis of the randomized,controlled,phase 3,non-inferiority TALENT study显示文摘Background:Albuvirtide is a once-weekly injectable human immunodeficiency virus(HIV)-1 fusion inhibitor.We present interim data for a phase 3 trial assessing the safety and efficacy of albuvirtide plus lopinavir-ritonavir in HIV-1-infected adults already treated with antiretroviral drugs.Methods:We carried out a 48-week,randomized,controlled,open-label non-inferiority trial at 12 sites in China.Adults on the World Health Organization(WHO)-recommended first-line treatment for>6 months with a plasma viral load>1000 copies/mL were enrolled and randomly assigned(1:1)to receive albuvirtide(once weekly)plus ritonavir-boosted lopinavir(ABT group)or the WHO-recommended second-line treatment(NRTI group).The primary endpoint was the proportion of patients with a plasma viral load below 50 copies/mL at 48 weeks.Non-inferiority was prespecified with a margin of 12%.Results:At the time of analysis,week 24 data were available for 83 and 92 patients,and week 48 data were available for 46 and 50 patients in the albuvirtide and NRTI groups,respectively.At 48 weeks,80.4%of patients in the ABT group and 66.0%of those in the NRTI group had HIV-1 RNA levels below 50 copies/mL,meeting the criteria for non-inferiority.For the per-protocol population,the superiority of albuvirtide over NRTI was demonstrated.The frequency of grade 3 to 4 adverse events was similar in the two groups;the most common adverse events were diarrhea,upper respiratory tract infections,and grade 3 to 4 increases in triglyceride concentration.Renal function was significantly more impaired at 12 weeks in the patients of the NRTI group who received tenofovir disoproxil fumarate than in those of the ABT group.Conclusions:The TALENT study is the first phase 3 trial of an injectable long-acting HIV drug.This interim analysis indicates that once-weekly albuvirtide in combination with ritonavir-boosted lopinavir is well tolerated and non-inferior to the WHO-recommended second-line regimen in patients with first-line treatment failure.Trial registration:ClinicalTrials.gov Identifier:NCT02369965;http://gffzz90ed6ce9d87f4798s6owwbcc66fp569up.ffgz.tsg.suse.edu.cn Clinical Trial Registry No.ChiCTR-TRC-14004276;http://gffzz62a03ee25e6f4a77h6owwbcc66fp569up.ffgz.tsg.suse.edu.cn/enindex.aspx. | Bin Su Cheng Yao Qing-Xia Zhao Wei-Ping Cai Min Wang Hong-Zhou Lu Yuan-Yuan Chen Li Liu Hui Wang Yun He Yu-Huang Zheng Ling-Hua Li Jin-Feng Chen Jian-Hua Yu Biao Zhu Min Zhao Yong-Tao Sun Wen-Hui Lun Wei Xia Li-Jun Sun Li-Li Dai Tai-Yi Jiang Mei-Xia Wang Qing-Shan Zheng Hai-Yan Peng Yao Wang Rong-Jian Lu Jian-Hua Hu Hui Xing Yi-Ming Shao Dong Xie Tong Zhang Fu-Jie Zhang Hao Wu TALENT Study Team | 2020 | Chinese Medical Journal2020，，24： | 10 |
| 11 | Liquid-FEP-based U-tube triboelectric nanogenerator for harvesting water-wave energy显示文摘收获周围的机械精力是为认识到自我动力的电子学的一种关键技术。与稳定性和耐久性的优点, liquid-solid-based 摩擦电 nanogenerator (TENG ) 最近引起了许多注意。然而, TENG 表演和相关工作原则上的液体性质的影响仍然是不清楚的。我们此处基于液体固体模式装配了 U 试管 TENG 并且使用了 11 液体在 TENG 输出性能上学习液体性质的效果。结果证实影响产量的关键因素是极性,绝缘的常数,和与氟化的乙烯丙烯(FEP ) 的亲密关系。在 11 液体之中,纯以水为基的U试管 TENG 与开电路的电压展出了最好的产量( V 81.7 V 和电线走火电流的 oc )(我 为摇晃的模式( 0.5 Hz )的 0.26 A 的 sc ),它能推进增加到 93.0 V 和 0.48 A ,分别地为水平变模式( 1.25 Hz )。U 试管 TENG 能与比 92% 高的精确性为一个水的答案作为一个自我动力的集中传感器(部件集中或 metalion 集中) 被利用。最后,升级的像三明治的 water-FEP U 试管 TENG 被使用收获水波浪精力,显示出有 V 350 V 的 oc ,我 1.75 A 的 sc ,和 2.04 W/m 3 的力量密度。我们成功地照亮了 60 LEDs 并且动力一温度湿度米。给它的高输出性能, water-FEP U 试管 TENG 是为为自我动力的电子学收获水波浪精力的一条很有希望的途径。 | Lun Pan Jiyu Wang Peihong Wang Ruijie Gao Yi-Cheng Wang Xiangwen Zhang Ji-Jun zou Zhong Lin Wang | 2018 | Nano Research2018，11，8： | 10 |
| 12 | Spectral characteristic of infrared radiations of some acupoint and non-acupoint areas in human arm surface显示文摘Using infrared spectrum detective device, we experiment on Neiguan, Laogong and Hegu acupoints of seven adult volunteers as well as contrastive points beside ones. We get 63 infrared spectrums. The experiment outcome tells us that the differences of the intensities among individuals are great, and so are the differences between acupoint and non-acupoint areas. However, the differences of spectral character are small, which indicates that infrared radiations of human body are based on the same biophysical fundament. | DING Guanghong YAO Wei CHU Junhao SHEN Xueyong HUANG Zhiming CHENG Huansheng LIU Hui WANG Shenzhang YANG Jing WEI Hu FEI Lun | 2001 | Chinese Science Bulletin2001，46，8： | 9 |
| 13 | MoSe2 porous microspheres comprising monolayer flakes with high electrocatalytic activity显示文摘综合的一条灵巧的胶体的线路 MoSe < 潜水艇 class= “ a-plus-plus ” > 2 有由 MoSe 组成的 400600 nm 的直径的多孔的 microspheres < 潜水艇 class= “ a-plus-plus ” > 2 个 单层薄片在厚度的 0.7 nm 被报导。溶剂 trioctylamine TOA 和 oleylamine 操作维护管理被发现在 MoSe 的形成起重要作用 < 潜水艇 class= “ a-plus-plus ” > 2 microspheres, TOA 由此决定三维的 3D microspherical 形态学和操作维护管理,指导 MoSe 的形成 < 潜水艇 class= “ a-plus-plus ” > 2 个 单层薄片。柔韧的 3D MoSe <潜水艇class=“ a-plus-plus ”> 2 microspheres 展览为 electrocatalytic 氢进化反应的显著活动和耐久性她在酸,维持 77 mV 的小发作过电位并且为 5 妈/厘米的当前的密度保留 100 mV 的小过电位<啜class=“ a-plus-plus ”>在 1,000 以后的 2 骑车。另外,类似的 3D WSe < 潜水艇 class= “ a-plus-plus ” > 2 microspheres 能被使用这个方法也准备。我们期望这条灵巧的胶体的线路能进一步被扩展综合将在域例如里发现应用的另外的多孔的结构在精力存储,催化作用,并且察觉到。 | Yejun Zhang Qiufang Gong Lun Li Hongchao Yang Yanguang Li Qiangbin Wang | 2015 | Nano Research2015，8，4： | 9 |
| 14 | Paleomagnetic data from the Late Carboniferous-Late Permian rocks in eastern Tibet and their implications for tectonic evolution of the northern Qiangtang-Qamdo block显示文摘We report paleomagnetic results from the Late Carboniferous-Late Permian strata in eastern Tibet (China), and aim to clarify the tectonic and paleogeographic evolution of the northern Qiangtang-Qamdo block, which is the key to the study of plate boundary between the Gondwanaland and the Eurasia during the late Paleozoic. Two hundred and nineteen samples-including limestone, muddy siltstone, basalt, lava, and tuff-were collected at 24 sites in the Upper Carboniferous and Middle-Upper Permian successions. A systematic study of rock magnetism and paleomagnetism yields three reliable paleomagnetic pole positions. Both hematite and magnetite occurred in the Late Carboniferous limestone samples. The demagnetization curve shows a characteristic double-component, with the remanent magnetization (ChRM) exhibiting a positive polarity (negative inclination). In the Late Permian limestone, tuff, and basalt, magnetic information were recorded primarily in magnetite, although a small fraction of them was found in hematite in basalt. The demagnetization curve illustrates a double or single component, with the ChRM showing a negative polarity (positive inclination), which has passed the classic fold test successfully. The single polarity features of the ChRM directions of the Late Carboniferous and Middle-Late Permian rocks are respectively related to the Kiaman positive and reversed polarities under the stratigraphic coordinates. This, in turn, indicates that both ChRMs directions represent the original remanence directions. By comparison with the previously published paleomagnetic results from the late Paleozoic rocks in the northern Qiangtang Range, we suggest that: (1) Qamdo and northern Qiangtang block were independent of each other during the Late Carboniferous to the Early Permian periods. The north Lancangjiang ocean basin between the two blocks may have closed before the Middle Permian and been involved in the continent-continent collision stage in the Late Permian-Early Triassic periods. (2) The northern Qiangtang-Qamdo Block paleogeographically was situated at low to intermediate latitudes in the Southern Hemisphere in the Late Carboniferous-Late Permian periods, and began to displace northward in the Early Triassic, with an amount of more than 5000 km northward transport from its current location. | CHENG Xin WU HanNing DIAO ZongBao WANG HaiJun MA Lun ZHANG XiaoDong YANG Gang HONG JingJing JI WenHua LI RongShe CHEN ShouJian ZHAO ZhenMing | 2013 | Science China Earth Sciences2013，56，7： | 8 |
| 15 | THE STRUCTURE OF ARMILLARIZIN,A NEW PROTOILLUDANE SESQUITERPENOID AROMATIC ESTER FROM ARMILLARIA MELLEA(VAHL.EX FR)QUEL.显示文摘A new protoilludane sesquiterpenoid aromatic ester,named armillarizin(1)has been isolated from the artificially cultured mycelium of Armillaria me-llea(Vahl.ex Fr)Quel.(Tricholomataceae).Its structure was deduced on the ba-sis of spectral analyses.The relative configuration was established from thenuclear Overhauser effects and from the values of ~1H-~1H coupling constants. | Jun Shan YANG Ya Lun SU Yu Lan WANG Xiao Zhang FENG De Quan YU Xiao Tian LIANG Institute of Materia Medica,Chinese Academy of Medical Sciences,Beijing,100050 | 1990 | Chinese Chemical Letters1990，1，2： | 8 |
| 16 | Comparison of Two Methods to Assess the Size Structure of Phytoplankton Community Assemblages, in Liaodong Bay, China显示文摘Liaodong Bay is one of the largest semi-enclosed bays located in Bohai Sea,in northeast China.It is an important feeding and spawning place,even wintering and breeding migration base for many marine organisms.The size structure of phytoplankton communities is a key feature of marine ecosystems and can be used as an indicator for algae disaster,but the methods to evalute is still challenging.Here,we compared the size-fractionated chlorophyll-a method with a high-throughout sequencing method in an evaluation of the size structure of phytoplankton assemblages in Liaodong Bay,China,in 2014.The proportion of picophytoplankton was estimated at just 19%according to the results based on size-fractionated chlorophyll-a,which likely represents a severe underestimation.The sequencing method confirmed that many kinds of phytoplankton species appeared in more than one size-fractionated filter membrane,with some even dominating where the filter membrane pore size was greater than the individual phytoplankton size.According to the sequencing method,the phytoplankton assemblages in Liaodong Bay were dominated by picophytoplankton(average proportion=44%),followed by the nanophytoplankton(average 32%),a composition that is more consistent with other studies.The sequencing method provides a more robust way to assess the size structure and taxonomic diversity of marine phytoplankton communities. | SONG Lun WU Jing DU Jing LI Nan WANG Kun WANG Peng | 2019 | Journal of Ocean University of China2019，18，5： | 8 |
| 17 | A prospective study of vertical transmission of hepatitis C virus显示文摘AprospectivestudyofverticaltransmissionofhepatitisCvirusSUNDeGui1,LIUCaiYun1,MENGZongDa2,SUNYongDe2,WANGShuCong1,YANGYu... | SUN De Gui 1, LIU Cai Yun 1, MENG Zong Da 2, SUN Yong De 2, WANG Shu Cong 1, YANG Yu Qi 1, LIANG Zheng Lun 3 and ZHUANG Hui 3 | 1997 | World Journal of Gastroenterology1997，3，2： | 8 |
| 18 | Consensus by Chinese Expert Panel on Chlamydia trachomatis-Resistant and Chlamydia trachomatis-Persistent Infection显示文摘 | Man-Li Qi Yuan-Li Guo Qian-Qiu Wang Xiang-Sheng Chen Jian-De Han Xiao-Hong Su Wen-Hui Lun Hao Cheng Jin-Hua Xu Hong-Qing Tian Li Che Zhi-Yuan Ya Wen-Li Feng Juan Jiang Ping-Yu Zhou Xian-Biao Zo Hong-Hui Xu Wei-Min Shi Jun Liu Lin Zhu Quan-Zhong Liu | 2017 | Chinese Medical Journal2017，，23： | 7 |
| 19 | Increased Chondrocyte Apoptosis in Kashin-Beck Disease and Rats Induced by T-2 Toxin and Selenium Deficiency显示文摘Objective To investigate chondrocyte apoptosis and the expression of biochemical markers associated with apoptosis in Kashin-Beck disease(KBD) and in an established T-2 toxin-and selenium(Se) deficiency-induced rat model. Methods Cartilages were collected from the hand phalanges of five patients with KBD and five healthy children. Sprague-Dawley rats were administered a selenium-deficient diet for 4 weeks prior to T-2 toxin exposure. The apoptotic chondrocytes were observed by terminal deoxynucleotidyl transferase d UTP nick end labeling staining. Caspase-3, p53, Bcl-2, and Bax proteins in the cartilages were visualized by immunohistochemistry, their protein levels were determined by Western blotting, and m RNA levels were determined by real-time reverse transcription polymerase chain reaction. Results Increased chondrocyte apoptosis was observed in the cartilages of children with KBD. Increased apoptotic and caspase-3-stained cells were observed in the cartilages of rats fed with normal and Se-deficient diets plus T-2 toxin exposure compared to those in rats fed with normal and Se-deficient diets. Caspase-3, p53, and Bax proteins and m RNA levels were higher, whereas Bcl-2 levels were lower in rats fed with normal or Se-deficiency diets supplemented with T-2 toxin than the corresponding levels in rats fed with normal diet. Conclusion T-2 toxin under a selenium-deficient nutritional status induces chondrocyte death, which emphasizes the role of chondrocyte apoptosis in cartilage damage and progression of KBD. | YANG Hao Jie ZHANG Ying WANG Zhi Lun XUE Sen Hai LI Si Yuan ZHOU Xiao Rong ZHANG Meng FANG Qian WANG Wen Jun CHEN Chen DENG Xiang Hua CHEN Jing Hong | 2017 | Biomedical and Environmental Sciences2017，30，5： | 7 |
| 20 | Three-dimensional image of hepatocellular carcinoma under confocal laser scanning microscope显示文摘AIM To investigate the application of confocallaser scanning microscopy(CLSM)in tumorpathology and three-dimensional( 3-D )reconstruction by CLSM in pathologic specimensof hepatocellular carcinoma(HCC).METHODS The 30μm thick sections were cutfrom the paraffin-embedded tissues of HCC,hyperplasia and normal liver,stained with DNAfluorescent probe YOYO-1 iodide and examinedby CLSM to collect optical sections of nuclei and3-D images reconstructed.RESULTS HCC displayed chaotic arrangementof carcinoma cell nuclei,marked pleomorphism,indented and irregular nuclear surface,andirregular and coarse chromatin texture.CONCLUSION The serial optical tomograms ofCLSM can be used to create 3-D reconstruction ofcancer cell nuclei.Such 3-D impressions mightbe helpful or even essential in making anaccurate diagnosis. | Wang Hai Zhang Shi Neng Zhu Shi Lun Lu Ya Lin Huang Peng Zhao | 2000 | World Journal of Gastroenterology2000，6，3： | 7 |
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