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| 1 | Antiproliferative role of Indig ofera aspalathoides on 20 methylcholanthrene induced fibrosarcoma in rats显示文摘Objective:To find out the anticancer effect of indigofera aspalathoides(L.aspalathoides)on20-methylcholanthrene induced fibrosarcoma in rats.Methods:Fibrosarcoma was induced in Wistar strain male albino rats by 2O-methylcholanthrene.Intraperitoneous(i.p.)administration of250 mg/kg body weight/day of aqueous extract of I.aspalathoides for 30 d effectively suppressed chemically induced tumors.Parameters such as body weight,liver and kidney weight,tumor weight,mean survival time,behavioral changes,blood glucose,blood glycogen and marker enzymes such as alanine aminotransferase(ALT),aspartate aminotransferase(AST),alkaline phosphatase(ALP),acid phosphatase(ACP)and 5'-nucleiotidase(5'-NT)in serum,liver and kidney and lipid profiles such as total cholesterel,phospholipids,free fatty acids in liver and kidney of control and experimental animals were studied.Results:Fibrosarcoma bearing animals were ferocious and anxious.The mean survival time was found to increase after the treatment.The body weights were significantly decreased(P<0.001)in groupⅡfibrosarcoma animals which steadily increased after the treatment with I.aspalathoides.The liver and kidney weights were significantly increased whereas the tumor weights decreased as compared to the weights in untreated fibrosarcoma bearing rats.The blood glucose and the liver and kidney glycogen levels were found to decrease significantly(P<0.001)in groupⅡanimals.Elevated activities of marker enzymes were observed in serum,liver and kidney of fibrosarcoma bearing GroupⅡanimals which were normalize after I.aspalathoides treatment.In the liver and kidney of GroupⅡanimals the total cholesterol increased whereas the pbospbolipids and free fatty acid levels decreased(P<0.001)which were normalized after treatment.Conclusions:The treatment by I.aspalathoides on fihrosarcoma bearing rats has improved the levels of various parameters indicating its antiproliferative and anticancer activity. | Sivagnanam Selva Kumar Mudiganti Ram Krishna Rao Maruthaiveeran Periyasamy Balasubramanian | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，12： | 2 |
| 2 | Molecular Mechanisms of Diabetic Retinopathy,General Preventive Strate- gies, and Novel Therapeutic Targets 显示文摘 | Sher Zaman Safi Rajes Qvist Selva Kumar | 2014 | Biomed Res Int2014，2014，3： | 1 |
| 3 | N and p doped poly(3,4- ethylenedioxythiophene) electrode materials for symmetric redox supercapacitors 显示文摘 | Bhat D Krishna Kumar M Selva | 2007 | Mater Sci2007，42，： | 1 |
| 4 | Indications for full prosthetic disc arthroplasty: a correlation of clinical outcome against a variety of indications显示文摘 | Rudolf Bertagnoli Selva Kumar | 2002 | European Spine Journal2002，，2： | 1 |
| 5 | Characterisation of titanium–titanium boride composites processed by powder metallurgy techniques显示文摘 | M. Selva Kumar P. Chandrasekar P. Chandramohan M. Mohanraj | 2012 | Materials Characterization2012，，： | 1 |
| 6 | A randomized trial of stenting with or without balloon predilation for the treatment of coronary artery disease显示文摘 | Lance I. Kovar E.Scott Monrad Warren Sherman Selva Kunchithapatham Kumar L. Ravi William Gotsis Gary Silverman David L. Brown | 2001 | American Heart Journal2001，，5： | 1 |
| 7 | Real-time decay of fluorinated fullerene molecules on Cu(001) surface controlled by initial coverage显示文摘在这研究, C 60 Cu (001 ) 表面上的 F 18 分子借助于扫描通道显微镜学和密度被学习功能的理论计算。结果显示出那氟化的 fullerenes (塑造龟的极的 C 60 Cu (001 ) 上的 F 18) 腐烂从 C 60 笼子由 F 原子的一个一步一步的分队出现。当时,最有利的吸附配置被认识到 C 60 向 Cu 表面和六个 F 原子削尖的 F 18 从它被分开。结果也显示出那 C 60 F 12 分子强烈取决于起始的 C 60 F 18 范围。开始形成的分开的 F 原子一二维(2D ) 然后慢慢地转变了成导致 F 的表面的煤气的阶段组织。在 C 60 F 12 分子和 Cu (001 ) 出现取决于 2D 气体阶段的密度。因此,氟化的 fullerenes 的一生被 2D 气体阶段的密度决定,它被新导致 F 的结构的形成和 C 60 F 12 分子。 | Andrey I. Oreshkin Dmitry A. Muzychenko Sergey I. Oreshkin Vladimir A. Yakovlev Palanichamy Murugan S. Selva Chandrasekaran Vijay Kumar Rauf Z. Bakhtizin | 2018 | Nano Research2018，11，4： | 0 |
| 8 | Monitoring on Guardrails to Afford Road Safety Using IOT显示文摘The preservation of the road infrastructures has become an important issue to the road safety and structural monitoring systems industry aiming to reduce the maintenance cost and also to increase the drivers safety. The collision features of the simulation of car- guard rail. It is found that the vibration features of the guardrail within the accident have a good performance to the accident identification. The vibration data of the guardrail are recorded real-timely by the nodes with accelerator sensors on the guardrail network. Then the collision accident is identified in terms of the vibration threshold. The proposed design is a system which can detect accidents in significantly less time and sends the basic information to first aid center within a few seconds covering geographical coordinate the time and angle in which a vehicle accident had occurred. This alert message is sent to the rescue team in a short time which will help in saving the valuable lives. | Selva Kumar Ranjith Kumar Roop Kishan Vignesh | 2018 | Journal of Autonomous Intelligence2018，1，2： | 0 |
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