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| 1 | Normal and disease-related biological functions of Twist1 and underlying molecular mechanisms显示文摘这篇文章在开发,基因疾病和癌症考察分子的结构,表达式模式,生理的函数,病理学的角色和 Twist1 的分子的机制。Twist1 是基本 helix-loop-helix 包含域的抄写因素。以便绑 Nde1 电子盒子元素并且激活或镇压形成 homo-dimers 或 hetero-dimers 它的目标基因。在开发期间, Twist1 为中层说明和区别是必要的。人的 Twist1 基因的异质接合的 loss-of-function 变化包括 Saethre-Chotzen 症候群引起几疾病。Twist1 空的老鼠胚胎与打开的头部的神经试管和有缺点的头间充组织死,体节和手足芽。Twist1 在胸被表示,肝,前列腺,胃并且癌症的另外的类型,和它的表示通常与侵略、变形的癌症显型被联系。在癌症房间, Twist1 是由包括 SRC-1 的多重因素的 upregulated, STAT3, MSX2, HIF-1α,连接 integrin 的 kinase 和 NF-κ B。Twist1 显著地提高上皮间充质的转变(EMT ) 和癌症房间移植和侵略,因此支持癌症转移。Twist1 由直接镇压部分地支持 EMT 由招募的 E-cadherin 表示改变的 nucleosome 和为基因压抑并且由 upregulating Bmi1 的 deacetylase 建筑群, AKT2, YB-1,等等。新兴的证据也建议 Twist1 在扩大和癌症干细胞的化学疗法的抵抗起一个作用。Twist1 由支持 Twist1 功能的调节的人的转移和鉴定的机制的进一步的理解可以为开发新策略禁止 EMT 和癌症转移保持诺言。 | Qian Qin Young Xu Tao He Chunlin Qin Jianming Xu | 2012 | Cell Research2012，22，1： | 66 |
| 2 | Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures显示文摘 | Bin-Kuan Chou Prashant Mali Xiaosong Huang Zhaohui Ye Sarah N Dowey Linda MS Resar Chunlin Zou Alex Zhang Jay Tong Linzhao Cheng | 2011 | Cell Research2011，21，3： | 38 |
| 3 | Development of a Chinese land data assimilation system:its progress and prospects显示文摘陆地数据吸收的目的是为改进陆地表面状态的评价把多来源观察合成陆地表面模型的动力学。我们为中国的陆地领土开发了一个陆地数据吸收系统。在这个系统,普通陆地模型和简单生物圈,模型 2 被用来模仿陆地表面过程。当转移的观察操作员为预言建模进估计的亮度温度,融化并且结冰的土壤,雪,湖,和植被的放射的转移模型被使用。一个 Monte-Carlo 顺序的过滤器,整体 Kalman 过滤器,作为数据吸收方法被实现集成当模特儿并且观察。系统能够遥远地吸收被动微波察觉到的数据象特殊传感器微波成像器那样(SSM 我) , TRMM 微波成像器(TMI ) ,和先进微波扫描辐射计为曙光女神(AMSRE ) 提高了并且在土壤和雪的 situmeasurements 常规。与 0.25 度的一个空间决定和一个小时的时间的分辨率,为土壤潮湿,土壤温度,雪和冻结的土壤的空间与时间地一致的吸收数据集被生产了。这篇论文介绍在数据吸收算法,陆地表面水文学变量的陆地表面建模微波遥感,和大气的强迫的数据的准备上做的中国陆地数据吸收系统和进步的开发。为未来开发开发陆地数据吸收系统和观点的不同特征和挑战也被讨论。 | Li Xin Huang Chunlin Che Tao Jin Rui Wang Shugong Wang Jiemin Gao Feng Zhang Shuwen Qiu Chongjian Wang Chenghai | 2007 | Progress in Natural Science:Materials International2007，17，8： | 30 |
| 4 | Modeling and Simulation on Axial Piston Pump Based on Virtual Prototype Technology显示文摘A particular emphasis is placed on the virtual prototype technology(VPT) of axial piston pump.With this technology it is convenient and flexible to build a complicated 3D virtual based on real physical model.The actual kinematics pairs of the parts were added on the model.The fluid characters were calculated by hydraulic software.The shape of the parts, the flexible body of parts, etc were improved in this prototype.So the virtual prototype of piston pump can work in computer like a real piston pump, and the flow ripple, pressure pulsation, motion principle, stress of parts, etc can be investigated.The development of the VPT is introduced at the beginning, and the modeling process of the virtual prototype is explained.Then a special emphasis is laid on the relationship between the dynamics model and the hydraulic model, and the simulations on the flow ripple, pressure pulsation, motion principle, the stress and strain distribution of the middle shaft and piston are operated.Finally, the advantages and disadvantages of the VPT are discussed.The improved virtual prototype of piston pump more tally with the real situation and the VPT has a great potential in simulation on hydraulic components. | ZHANG Bin XU Bing XIA Chunlin YANG Huayong | 2009 | Chinese Journal of Mechanical Engineering2009，22，1： | 29 |
| 5 | Neuroprotective effects of rutaecarpine on cerebral ischemia reperfusion injury显示文摘Rutaecarpine,an active component of the traditional Chinese medicine Tetradium ruticarpum,has been shown to improve myocardial ischemia reperfusion injury.Because both cardiovascular and cerebrovascular diseases are forms of ischemic vascular disease,they are closely related.We hypothesized that rutaecarpine also has neuroprotective effects on cerebral ischemia reperfusion injury.A cerebral ischemia reperfusion model was established after 84,252 and 504 μg/kg rutaecarpine were given to mice via intraperitoneal injection,daily for 7 days.Results of the step through test,2,3,5-triphenyl tetrazolium chloride dyeing and oxidative stress indicators showed that rutaecarpine could improve learning and memory ability,neurological symptoms and reduce infarction volume and cerebral water content in mice with cerebral ischemia reperfusion injury.Rutaecarpine could significantly decrease the malondialdehyde content and increase the activities of superoxide dismutase and glutathione peroxidase in mouse brain.Therefore,rutaecarpine could improve neurological function following injury induced by cerebral ischemia reperfusion,and the mechanism of this improvement may be associated with oxidative stress.These results verify that rutaecarpine has neuroprotective effects on cerebral ischemia reperfusion in mice. | Chunlin Yan Ji Zhang Shu Wang Guiping Xue Yong Hou | 2013 | Neural Regeneration Research2013，8，22： | 20 |
| 6 | The Arabidopsis PRCl-like ring-finger proteins are necessary for repression of embryonic traits during vegetative growth显示文摘Polycomb 组基因在维护起关键作用 transcriptionally 为在动物和植物的合适的房间区别的基因的 silenced 状态。当时 polycomb 的部件压抑的 complex2 (PRC2 ) evolutionarily 被保存,他们的功能广泛地在植物被学习, PRC1 在动物和植物之间更加不同,并且它在植物的功能是不好迄今为止描述了。以前的研究作为动物 PRC1 子单元 RING1 的相当或相同事物识别了 Arabidopsis AtRING1a 和 AtRING1b。这里,我们证明 Atring1a Atring1b 双异种在植物的生长期间展出胚胎的特点的 derepression。因此,几关键规章的基因在 embryogenesis 包含了,干细胞活动宫外地在异种被表示。而且,我们证明变异的显型和规章的基因的增加的表示被 PRC2 变异的 clf 提高。最后,我们显示出那动物 PRC1 子单元戒指手指蛋白质 BMI1, AtBMI1a, AtBMI1b 和 AtBMI1c 的三个相当或相同事物,罐头与 AtRING1a 或 AtRING1b 绑,并且另外, AtBMI1c 能与 LHP1 绑。Atbmi1a Atbmi1b 双异种显示出类似于 Atring1a Atring1b 双异种的胚胎的特点的 derepression。有趣地, AtBMI1a, AtBMI1b 和 AtBMI1c 的表示层次在 Atring1a Atring1b 异种被提高,那些在 Atbmi1a Atbmi1b 异种 AtBMI1c, AtRING1a 和 AtRING1b 被提高,建议自我规章的反馈机制。一起拿,我们的结果为合适的体的生长在胚胎的特点和规章的基因的稳定的压抑照亮象 PRC1 一样戒指手指部件的关键功能。 | Donghong Chen Anne Molitor Chunlin Liu Wen-Hui Shen | 2010 | Cell Research2010，20，12： | 19 |
| 7 | High-resolution geochemistry records of climate changes since late-glacial from Dajiuhu peat in Shennongjia Mountains,Central China显示文摘A peat core with depths of 297 cm was obtained from the Dajiuhu Basin(31°29′27″N,109°59′45″E,1760 m)in Hubei Province,Central China.10 AMS ages provide a time control and reveal that this core spans the past about 16.0 kaBP(calibrated age)(1 4C age:13.3 kaBP).Multi-proxy indexes analysis of geochemistry shows the following character of climate and environmental changes since about 16 kaBP:(1) The climate during the late-glacial period was cold and wet as a whole,but fluctuated continually.11.4- 12.6 cal.kaBP,12.6-15.2 cal.kaBP and 15.2-16 kaBP were corresponding respectively to the Younger Drays,Bφlling-Allerφd Warm Period and the Oldest Drays.(2)Inheriting the some climate characteristics of the late-glacial,the climate during the early-Holocene was wet and temperature increased gradually,during which an obvious dry event around 10.6 cal.kaB appeared.(3)The climate during the mid-Holocene was genarally warm and wet.During 9.2-7.5 kaBP,temperature increased gradually, precipitation was less comparatively and the 8.2 kaBP cold event which might be representative in the globe was reflected markedly.Then,multi-proxy records were relatively stable during 6.7-4.2 kaBP, which shows the best water and thermal condition in the Holocene Optimum.(4)Around 4.2 kaBP,the climate and environment transform from warm and wet to cool and dry,which may result in the collapse of the Neolithic Culture and midwifery the civilization of Xia Dynasty in this region.After 0.9 kaBP,the climate turned cool and wet.Climate and environmental changes archived in Dajiuhu peat respond to the global changes since the late-glacial period and can be contrasted to the changes recorded in other high-resolution archives from the East Asia Monsoon region,which take on the variety model that the monsoon strengthened abruptly after the late-glacial,was strong during the early Holocene,subse- quently declined and became weak after the middle Holocene with dry climate.According to our analysis,the driving mechanism should be the response of solar radiation changes in the East Asia Monsoon region at middle latitudes. | MA ChunMei ZHU Cheng ZHENG ChaoGui WU ChunLin GUAN Yong ZHAO ZhiPing HUANG LinYan HUANG Run | 2008 | Chinese Science Bulletin2008，53，S1： | 19 |
| 8 | Down.regulation of E.cadherin enhances prostate cancer chemoresistance via Notch signaling显示文摘Background:The chemoresistance of prostate cancer(PCa)is invariably associated with the aggressiveness and metastasis of this disease.New emerging evidence indicates that the epithelial-to-mesenchymal transition(EMT)may play pivotal roles in the development of chemoresistance and metastasis.As a hallmark of EMT,E-cadherin is suggested to be a key marker in the development of chemoresistance.However,the molecular mechanisms underlying PCa chemoresistance remain unclear.The current study aimed to explore the association between EMT and chemoresistance in PCa as well as whether changing the expression of E-cadherin would affect PCa chemoresistance.Methods:Parental PC3 and DU145 cells and their chemoresistant PC3-Tx R and DU145-Tx R cells were analyzed.PC3-Tx R and DU145-Tx R cells were transfected with E-cadherin-expressing lentivirus to overexpress E-cadherin;PC3 and DU145 cells were transfected with small interfering RNA to silence E-cadherin.Changes of EMT phenotype-related markers and signaling pathways were assessed by Western blotting and quantitative real-time polymerase chain reaction.Tumor cell migration,invasion,and colony formation were then evaluated by wound healing,transwell,and colony formation assays,respectively.The drug sensitivity was evaluated using MTS assay.Results:Chemoresistant PC3-Tx R and DU145-Tx R cells exhibited an invasive and metastatic phenotype that associated with EMT,including the down-regulation of E-cadherin and up-regulation of Vimentin,Snail,and N-cadherin,comparing with that of parental PC3 and DU145 cells.When E-cadherin was overexpressed in PC3-Tx R and DU145-Tx R cells,the expression of Vimentin and Claudin-1 was down-regulated,and tumor cell migration and invasion were inhibited.In particular,the sensitivity to paclitaxel was reactivated in E-cadherin-overexpressing PC3-Tx R and DU145-Tx R cells.When E-cadherin expression was silenced in parental PC3 and DU145 cells,the expression of Vimentin and Snail was up-regulated,and,particularly,the sensitivity to paclitaxel was decreased.Interestingly,Notch-1 expression was up-regulated in PC3-Tx R and DU145-Tx R cells,whereas the E-cadherin expression was down-regulated in these cells comparing with their parental cells.The use ofγ-secretase inhibitor,a Notch signaling pathway inhibitor,significantly increased the sensitivity of chemoresistant cells to paclitaxel.Conclusion:The down-regulation of E-cadherin enhances PCa chemoresistance via Notch signaling,and inhibiting the Notch signaling pathway may reverse PCa chemoresistance. | Wenchu Wang Lihui Wang Atsushi Mizokami Junlin Shi Chunlin Zou Jinlu Dai Evan T. Keller Yi Lu Jian Zhang | 2017 | Chinese Journal of Cancer2017，36，3： | 16 |
| 9 | Issues and solutions toward zinc anode in aqueous zinc-ion batteries: A mini review显示文摘Aqueous zinc-ion batteries(ZIBs)have been intensively investigated as potential energy storage devices on account of their low cost,environmental benignity,and intrinsically safe merits.With the exploitation of highperformance cathode materials,electrolyte systems,and in-depth mechanism investigation,the electrochemical performances of ZIBs have been greatly enhanced.However,there are still some challenges that need to be overcome before its commercialization.Among them,the obstinate dendrites,corrosion,and hydrogen evolution reaction(HER)on Zn anodes are critical issues that severely limit the practical applications of ZIBs.To address these issues,various strategies have been proposed,and tremendous progress has been achieved in the past few years.In this article,we analyze the origins and effects of the dendrites,corrosion,and HER on Zn anodes in neutral and mildly acid aqueous solutions at first.And then,a scientific understanding of the fundamental design principles and strategies to suppress these problems are emphasized.Apart from these,this article also puts forward some requirements for the practical applications of Zn anodes as well as several cost-effectivemodifying strategies.Finally,perspectives on the future development of Zn anodes in aqueous solutions are also briefly anticipated.This article provides pertinent insights into the challenges on anodes for the development of highperformance ZIBs,which will greatly contribute to their practical applications. | Chunlin Xie Yihu Li Qi Wang Dan Sun Yougen Tang Haiyan Wang | 2020 | Carbon Energy2020，2，4： | 15 |
| 10 | Combining CLUE-S and SWAT Models to Forecast Land Use Change and Non-point Source Pollution Impact at a Watershed Scale in Liaoning Province, China显示文摘Non-point source(NPS) pollution has become a major source of water pollution. A combination of models would provide the necessary direction and approaches designed to control NPS pollution through land use planning. In this study, NPS pollution load was simulated in urban planning, historic trends and ecological protection land use scenarios based on the Conversion of Land Use and its Effect at Small regional extent(CLUE-S) and Soil and Water Assessment Tool(SWAT) models applied to Hunhe-Taizi River Watershed, Liaoning Province, China. Total nitrogen(TN) and total phosphorus(TP) were chosen as NPS pollution indices. The results of models validation showed that CLUE-S and SWAT models were suitable in the study area. NPS pollution mainly came from dry farmland, paddy, rural and urban areas. The spatial distribution of TN and TP exhibited the same trend in 57 sub-catchments. The TN and TP had the highest NPS pollution load in the western and central plains, which concentrated the urban area and farm land. The NPS pollution load would increase in the urban planning and historic trends scenarios, and would be even higher in the urban planning scenario. However, the NPS pollution load decreased in the ecological protection scenario. The differences observed in the three scenarios indicated that land use had a degree of impact on NPS pollution, which showed that scientific and ecologically sound construction could effectively reduce the NPS pollution load in a watershed. This study provides a scientific method for conducting NPS pollution research at the watershed scale, a scientific basis for non-point source pollution control, and a reference for related policy making. | LIU Miao LI Chunlin HU Yuanman SUN Fengyun XU Yanyan CHEN Tan | 2014 | Chinese Geographical Science2014，24，5： | 15 |
| 11 | Simulation and study on mitigation measures of frequent subsynchronous oscillation with low amplitude at multi-power plants显示文摘Subsynchronous oscillation (SSO) with low amplitude that exceeds cumulative fatigue threshold of the generator shaft frequently could significantly reduce the shaft's service life, which is a new SSO problem that emerges in recent years. According to the real recording oscillograph, the basic reason for frequently over-threshold SSO with low amplitude at multi-power plants was analyzed based on Hulunbuir League system. The sensitivities of the electrical damping to the main electrical parameters in the contributing loop of subsynchronous torsional interaction were calculated. Based on the sensitivities, a simulation method was presented, which was used to excite the same oscillation as the actual case by exerting disturbance on the firing angle. The limitation of wide-band and narrow-band supplementary subsynchronous damping controller (SSDC) for mitigating this kind of SSO was analyzed based on the electromagnetic transient simulation model of Hulunbuir League system. The difference of supplementary excitation damping controller (SEDC) and parallel-form FACTS connected to the generator terminal was compared from the aspects of response time and the ability of damping torque supplying. The analysis indicates that their response time is similar but FACTS has stronger ability of damping torque supplying than SEDC. Time-domain simulation method was used to compare the mitigation effects of SEDC, static var compensator (SVC) and static synchronous compensator (STATCOM). Considering the mitigation effect, the floor space limit of the power plant and so on, STATCOM was considered as the best mitigation measure. A control strategy of cascaded STATCOM for engineering application was presented and the capacity for SSO mitigation as well as output characteristics was analyzed. The analysis indicates that STATCOM using the proposed control strategy has better mitigation effect and output characteristics with smaller capacity. | XIAO XiangNing ZHANG Jian GAO BenFeng WU YunSheng LUO Chao GUO ChunLin YANG Lin | 2013 | Science China(Technological Sciences)2013，56，6： | 13 |
| 12 | Simultaneous Screening of 733 Pesticide Residues in Fruits and Vegetables by a GC/LC-Q-TOFMS Combination Technique显示文摘In this paper,we report the construction of two accurate mass databases and the development of a combination detection method that simultaneously screens for 733 pesticide and chemical contaminant multi-residues via high-throughput liquid chromatography(LC)-and gas chromatography(GC)-quadru pole-time-of-flight mass spectrometry(Q-TOFMS).This work demonstrates that electronic mass spectral standards may replace chemical-source standard materials as references through one sample preparation and the combination of GC/LC-Q-TOFMS screening.This cutting-edge technique has also replaced multiresidue determination using targeted detection with non-targeted screening.The pesticide residue types,sensitivity,recovery,and reproducibility of this combination technique are evaluated in eight fruit and vegetable matrices.This technique shows three advantages:①In comparison with the discovery capability of a single technique,the combination technique shows an improvement of 51.1%(GC-QTOFMS)and 39.6%(LC-Q-TOFMS),respectively;②the combination technique can satisfy a screening limit lower than 10μg·kg^-1 and meet the requirements of“uniform standards,”although some of the pesticide residues could be optimized to further improve screening sensitivity;③over 488 pesticides with recoveries between 60%-120%and relative standard deviation(RSD)<20%at a spiked level of 10μg·kg^-1 were detected with the combination technique in eight different matrices.From 2012 to 2017,this combination technique was applied in an investigation to screen pesticide residues from 1384 sampling locations for 38138 batched samples covering 18 categories and 134 types of fruits and vegetables obtained from across the mainland of China.After statistical analysis,533 pesticides in 115891 determinations were detected,and the regularity of pesticides in the fruits and vegetables sold on the Chinese market was shown. | Guofang Pang Qiaoying Chang Ruobin Bai Chunlin Fan Zijuan Zhang Hongyuan Yan Xingqiang Wu | 2020 | Engineering2020，6，4： | 11 |
| 13 | Neural Networks Combined with Importance Sampling Techniques for Reliability Evaluation of Explosive Initiating Device显示文摘Concerning the issue of high-dimensions and low-failure probabilities including implicit and highly nonlinear limit state function, reliability analysis based on the directional importance sampling in combination with the radial basis function (RBF) neural network is used, and the RBF neural network based on first-order reliability method (FORM) is to approximate the unknown implicit limit state functions and calculate the most probable point (MPP) with iterative algorithm. For good efficiency, based on the ideas that directional sampling reduces dimensionality and importance sampling focuses on the domain contributing to failure probability, the joint probability density function of importance sampling is constructed, and the sampling center is moved to MPP to ensure that more random sample points draw belong to the failure domain and the simulation efficiency is improved. Then the numerical example of initiating explosive devices for rocket booster explosive bolts demonstrates the applicability, versatility and accuracy of the approach compared with other reliability simulation algorithm. | GONG Qi ZHANG Jianguo TAN Chunlin WANG Cancan | 2012 | Chinese Journal of Aeronautics2012，25，2： | 10 |
| 14 | Enhanced efficiency of cadmium removal by Boehmeria nivea(L.) Gaud. in the presence of exogenous citric and oxalic acids显示文摘Boehmeria nivea(L.)Gaud.is a potential candidate for the remediation of Cd contaminated sites.The present investigation aims to explore Cd tolerance threshold and to quickly identify the role of exogenous organic acids in Cd uptake and abiotic metal stress damage.Elevated Cd levels(0–10 mg/L)resulted in an obvious rise in Cd accumulation,ranging from268.0 to 374.4 in root and 25.2 to 41.2 mg/kg dry weight in shoot,respectively.Citric acid at1.5 mmol/L significantly facilitated Cd uptake by 26.7%in root and by 1-fold in shoot,respectively.Cd translocation efficiency from root to shoot was improved by a maximum of66.4%under 3 mmol/L of oxalic acid.Citric acid exhibited more prominent mitigating effect than oxalic acid due to its stronger ligand affinity for chelating with metal and avoiding the toxicity injury of free Cd ions more efficiently.The present work provides a potential strategy for efficient Cd remediation with B.nivea. | Huaying Li Yunguo Liu Guangming Zeng Lu Zhou Xin Wang Yaqin Wang Chunlin Wang Xinjiang Hu Weihua Xu | 2014 | Journal of Environmental Sciences2014，26，12： | 10 |
| 15 | Linkage between permafrost distribution and river runoff changes across the Arctic and the Tibetan Plateau显示文摘River runoff in the Arctic and the Tibetan Plateau(TP) change significantly in recent decades. However, the mechanisms of the physical processes of permafrost river runoff change remain uncertain across large scale. This study investigated the mainstreams and tributaries of main Arctic and TP rivers dominated by permafrost and assessed the linkage between hydrological regime change and permafrost. The results show that the effects of permafrost on river runoff are highly dependent on the permafrost coverage of a watershed. For the past decades, the majority of the Arctic and TP basins showed increased discharge, while all of the studied basins showed increased baseflow, with faster increasing speed than total discharge.Both total discharge and baseflow annual change rate(ΔQ and ΔBF) increased with permafrost coverage, indicating the increments of streamflow are enhanced with high permafrost coverage. Meanwhile, the annual change of precipitation showed weak connection with total discharge and baseflow change. The high permafrost coverage basins showed high annual maximum/minimum discharge ratio(Qmax/Qmin), while the Qmax/Qminchanged slightly in low permafrost cover basins. Our results highlight the importance of permafrost coverage on streamflow regime change for permafrost basins across the northern hemisphere. Due to these linkage between permafrost extent and runoff regime change and the increasing changes of permafrost, more attention should be paid to the change of hydrological processes in permafrost-underlain basins. | Chunlin SONG Genxu WANG Tianxu MAO Junchen DAI Daqing YANG | 2020 | Science China Earth Sciences2020，63，2： | 10 |
| 16 | Deformation Stages and Ar-Ar Age Data of the Wan-Zhe-Gan Tectonic Zone,Southeast China,and Their Tectonic Significance显示文摘在东南中国通过安徽,浙江,和江西省的边阶区域的主要构造地区通常被叫作 Wan-Zhe-Gan 差错地区。地质上,这个地区由各种各样的年龄和取向的几条地区性的差错带组成。我们基于地调查把差错分成了四个年龄组。Neoproterozoic 差错向东北正在罢工。他们从东北江西省开始并且延长对在安徽省的 Fuchuan 向东北,东北 Jiangxi-Fuchuan ophiolite 带的一样的地点。可能作为一条边界在 Neoproterozoic 期间扮演的差错与 m 指责一个盘子或块缝术的地区 ???? | YU Xinqi WANG De'en JIANG Dazhi JIANG Laili ZHOU Xiang LI Chunlin | 2011 | Acta Geologica Sinica(English Edition)2011，85，6： | 10 |
| 17 | On Uplink Non-Orthogonal Multiple Access for 5G:Opportunities and Challenges显示文摘In this paper,the concept of grantfree non-orthogonal multiple access(NOMA) for uplink data transmission is elaborated.NOMA in combination with grant-free can be applied to ultra reliability low latency communication(URLLC),massive machine type communication(m MTC),enhanced mobile broadband(e MBB) small packet and two-step random-access channel(RACH) scenarios.The advantages of grant-free NOMA are low latency and signaling overhead,high access capability and efficient resource utilization.Candidate uplink NOMA schemes are summarized and preliminary comparison among a subset of schemes are presented.Furthermore,design aspects for grant-free NOMA are discussed,with special notes on particular issues such as blind UE identification and transmitter/receiver(Tx/Rx) impairments in realistic deployment. | Li Tian Chunlin Yan Weimin Li Zhifeng Yuan Wei Cao Yifei Yuan | 2017 | China Communications2017，14，12： | 9 |
| 18 | Labeling of cynomolgus monkey bone marrow-derived mesenchymal stem cells for cell tracking by multimodality imaging显示文摘Recently,transplantation of allogeneic and autologous cells has been used for regenerative medicine.A critical issue is monitoring migration and homing of transplanted cells,as well as engraftment efficiency and functional capability in vivo.Monitoring of superparamagnetic iron oxide(SPIO) particles by magnetic resonance imaging(MRI) has been used in animal models and clinical settings to track labeled cells.A major limitation of MRI is that the signals do not show biological characteristics of transplanted cells in vivo.Bone marrow mesenchymal stem cells(MSCs) have been extensively investigated for their various therapeutic properties,and exhibit the potential to differentiate into cells of diverse lineages.In this study,cynomolgus monkey MSCs(cMSCs) were labeled with Molday ION Rhodamine-BTM(MIRB),a new SPIO agent,to investigate and characterize the biophysical and MRI properties of labeled cMSCs in vitro and in vivo.The results indicate that MIRB is biocompatible and useful for cMSCs labeling and cell tracking by multimodality imaging.Our method is helpful for detection of transplanted stem cells in vivo,which is required for understanding mechanisms of cell therapy. | REN ZhenHua WANG JiaYin ZOU ChunLin GUAN YunQian ZHANG Yu Alex | 2011 | Science China(Life Sciences)2011，54，11： | 9 |
| 19 | Multifunctional barium titanate ceramics via chemical modification tuning phase structure显示文摘Global environmental concerns on the toxicity of lead-based piezoelectrics impel the great mass fervor on investigations of lead-free alternatives.Barium titanate(BaTiO3,BT)ceramics,the first discovered perovskite ferroelectrics,were widely employed to fabricate dielectric capacitors from 1950s.Since a piezoelectric breakthrough was achieved via chemical modification,intensive researches have been performed embracing lead-free BT-based piezoelectrics and their extensional functionalities.In this review,we encompass the stateof-the-art progress on chemical modification tuning phase structure toward advanced electrical properties in BT-based ceramics.Generally,modulated regularity of cations substitution on phase transition is summarized and clarified.Then,we highlight the common methodologies of phase structure(phase boundary,relaxor phase,room-temperature phase transition,etc.)design for optimizing piezoelectricity,electrostrictive strain,electrocaloric,dielectric energy storage or permittivity performances,and cover the noticeable developments and relevant physical mechanisms.Finally,perspectives and challenges on future research issues are featured.This review proposes to exert the significant guidance and service for material design of BT-based and other lead-free perovskite materials with superior functionalities. | Chunlin Zhao Yanli Huang Jiagang Wu | 2020 | InfoMat2020，2，6： | 9 |
| 20 | 2,5-Furandicarboxylic acid production via catalytic oxidation of 5-hydroxymethylfurfural:Catalysts,processes and reaction mechanism显示文摘Biomass conversion to value-added chemicals has received tremendous attention for solving global warming issues and fossil fuel depletion.5-Hydroxymethylfurfural(HMF)is a key bio-based platform molecule to produce many useful organic chemicals by oxidation,hydrogenation,polymerization,and ring-opening reactions.Among all derivatives,the oxidation product 2,5-furandicarboxylic acid(FDCA)is a promising alternative to petroleum-based terephthalic acid for the synthesis of biodegradable plastics.This review analytically discusses the recent progress in the thermocatalytic,electrocatalytic,and photocatalytic oxidation of HMF into FDCA,including catalyst screening,synthesis processes,and reaction mechanism.Rapid fundamental advances may be possible in non-precious metal and metal-free catalysts that are highly efficient under the base-free conditions,and external field-assisted processes like electrochemical or photoelectrochemical cells. | Chunlin Chen Lingchen Wang Bin Zhu Zhenqiang Zhou Soliman I.El-Hout Jie Yang Jian Zhang | 2021 | Journal of Energy Chemistry2021，30，3： | 9 |
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