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| 1 | Assessment of lymph node involvement in colorectal cancer显示文摘Lymph node metastasis informs prognosis and is a key factor in deciding further management, particularly adjuvant chemotherapy. It is core to all contemporary staging systems, including the widely used tumor node metastasis staging system. Patients with nodenegative disease have 5-year survival rates of 70%-80%, implying a significant minority of patients with occult lymph node metastases will succumb to disease recurrence. Enhanced staging techniques may help to identify this subset of patients, who might benefit from further treatment. Obtaining adequate numbers of lymph nodes is essential for accurate staging. Lymph node yields are affected by numerous factors, many inherent to the patient and the tumour, but others related to surgical and histopathological practice. Good lymph node recovery relies on close collaboration between surgeon and pathologist. The optimal extent of surgical resection remains a subject of debate. Extended lymphadenectomy, extra-mesenteric lymph node dissection, high arterial ligation and complete mesocolic excision are amongst the surgical techniques with plausible oncological bases, but which are not supported by the highest levels of evidence. With further development and refinement, intra-operative lymphatic mapping and sentinel lymph node biopsy may provide a guide to the optimum extent of lymphadenectomy, but in its present form, it is beset by false negatives, skip lesions and failures to identify a sentinel node. Once resected, histopathological assessment of the surgical specimen can be improved by thorough dissection techniques, step-sectioning of tissue blocks and immunohistochemistry. More recently, molecular methods have been employed. In this review, we consider the numerous factors that affect lymph node yields, including the impact of the surgical and histopathological techniques. Potential future strategies, including the use of evolving technologies, are also discussed. | Mark L H Ong John B Schofield | 2016 | World Journal of Gastrointestinal Surgery2016，8，3： | 8 |
| 2 | Medial temporal lobe atrophy on MRI scans and the diagnosis of Alzheimer disease显示文摘 | R Duara D A. Loewenstein E Potter J Appel M T. Greig R Urs Q Shen A Raj B Small W Barker E Schofield Y Wu H Potter | 2008 | Neurology2008，，24： | 2 |
| 3 | Post-collisional magmatism in the central East African orogen: The Maevarano suite of north Madagascm显示文摘 | Goodenough K M Thomas R J De Waele B Key R M Schofield D I Bauer W Tucker R D Kafahatelo J M Rabrimanana M Ralison A V Randriamananjma T | 2010 | Lithos2010，116，12： | 1 |
| 4 | The traditional Chinese herbal formula ASHMI inhibits allergic lung inflammationin antigen-sensitized and antigen-challenged aged mice显示文摘 | Busse P J Schofield B Birmingham N Yang N Wen MC Zhang T Srivastava K Li XM | | 0，，03： | 1 |
| 5 | The dynamic rheological properties of glutens and gluten subfranctions fome wheat of good and poor bread-making quality 显示文摘 | Khatkar B S Bell A E Schofield J D | 1995 | Journal of Ce- real Science1995，22，： | 1 |
| 6 | The dynamic rheological properties of glutens and gluten subfranctions from wheat of good and poor bread-making quality显示文摘 | Bell A E Schofield J D | 1995 | Journal of Cereal Science1995，22，： | 1 |
| 7 | Decrease in airway mucous gene expression caused by treatment with anti-tumor necrosis factor in a murine model of allergic asthma显示文摘 | Busse PJ Zhang TF Schofield B | 2009 | Ann Allergy Asth- ma Immunol2009，103，4： | 1 |
| 8 | Is symptom bur- den a predictor of anxiety and depression in patients with cancer about to commence chemotherapy ?显示文摘 | Breen S J B aravelli C M Schofield PE | 2009 | Med Aust2009，190，7： | 1 |
| 9 | Segmentation and tracking of piglets in images显示文摘 | Mc Farlane N J B Schofield C P | 1995 | Machine Vision and Applications1995，8，： | 1 |
| 10 | Part VI some dioxindoles and their conversion into o-aminoaryl ketones显示文摘 | Mills B Schofield K Indoles | 1961 | Journal of the Chemical Society:1961，65，： | 1 |
| 11 | Mielichhoferia mielichhoferiana in the Southern Appalachians显示文摘 | SCHOFIELD W B | 1959 | The Bryologist1959，62，4： | 1 |
| 12 | Role of virtual reality in safety training of mine personnel 显示文摘 | B Denby D Schofield | 1999 | Mining Engineering1999，，10： | 1 |
| 13 | Role of K+and amino acids in osmoregulation by the free-living microaero-philic protozoon Hexamita inflate显示文摘 | Biagini A B Kirk K Schofield P J | 2000 | Microbiology2000，146，： | 1 |
| 14 | The Dynamic Rheological Properties of Glutens and Gluten Subfractions from Wheats of Good and Poor Bread-Making Quality 显示文摘 | Khatkar B S Bell A E Schofield J D | 1995 | Journal of Cereal Science1995，22，： | 1 |
| 15 | Role of virtual reality in safety training of mine personnel 显示文摘 | Denby B Schofield D | 1999 | Mining Engineering1999，51，10： | 1 |
| 16 | Projections from the auditory cortex to the superior olivary complex in guinea pigs显示文摘 | COOMES D L SCHOFIELD B R | 2004 | Eur J Neurosci2004，19，： | 1 |
| 17 | The immunoloeation of friabilin and its association with wheat endosperm texture 显示文摘 | Brennan C S Sulaiman B D Schofield J D | 1993 | Aspects of Applied Biology1993，36，： | 1 |
| 18 | Repeated peripheral airway hyperpnea causes inflammation and remodeling in dogs 显示文摘 | Davis MS Schofield B Freed AN | 2003 | Med Sci Sports Exerc2003，35，4： | 1 |
| 19 | Role of Virtual Reality in Safety Training of Mine Personnel 显示文摘 | DENBY B SCHOFIELD D | 1999 | Mining Engineering1999，28，10： | 1 |
| 20 | Scottish foot ulcer risk score predicts foot ulcer healing in a regional specialist foot clinic显示文摘 | Leese G Schofield C McMurray B | | 0，，08： | 1 |
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