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| 1 | Isolation and characterization of bipotent liver progenitor cells from adult mouse显示文摘 | Li WL Su J Yao YC Tao XR Yan YB Yu HY Wang XM Li JX Yang YJ Lau JT HuYP | 2006 | 中国生物学文摘2006，20，5： | 26 |
| 2 | Some characteristics and evolution of the internal soliton in the northern South China Sea显示文摘Based on the observational data of an internal soliton in the northern South China Sea (SCS) on June 14, 1998, the possible source of the internal soliton is analyzed, and some of its characteristic parameters such as phase speed, wave length, etc. are computed. Based on the analyses of the vertical modes of the internal wave, the characteristics of the wave-induced current during the propagation of the internal soliton are studied. A regularized long wave (RLW) equation numerical model considering effects of multi-fac-tors is employed, and the observed environmental parame-ters are used as the initial conditions to simulate the propa-gation and evolution of the internal soliton in the continental shelf of the northern SCS. | Cai, SQ Gan, ZJ Long, XM | 2002 | Chinese Science Bulletin2002，47，1： | 23 |
| 3 | Late Mesozoic crust-mantle interaction in southeastern Fujian——Isotopic evidence from the Pingtan igneous complex显示文摘UNDERPLATING Of mantle-derived basaltic magma and interacting with the lower crust materials are believed to be an important mechanism for the growth and transformation of the crust. | Dong, CW Zhou, XM Li, HM Ren, SL Zhou, XH | 1997 | Chinese Science Bulletin1997，42，6： | 23 |
| 4 | Codon 249 mutations of p53 gene in development of hepatocellular carcinoma显示文摘Codon249mutationsofp53geneindevelopmentofhepatocelularcarcinomaPENGXiaoMou,PENGWenWeiandYAOJiLuSubjectheadingsliverneopla... | Peng, XM Peng, WW Yao, JL | 1998 | World Journal of Gastroenterology1998，4，2： | 18 |
| 5 | 门静脉高压并非肝细胞癌肝切除术的绝对禁忌证显示文摘在肝细胞癌(hepatocellular carcinoma,HCC)的各种临床分期系统中,Bruix J团队领衔的巴塞罗那肝癌临床分期标准(Barcelona Clinic Liver Cancer,BCLC)最受推崇,美国和欧洲肝病协会指南的制定亦基于该分期系统。BCLC认为门静脉高压显著增加HCC肝切除术后患者发生肝功能衰竭的风险, | Zhong JH Li H Xiao N Ye XP Ke Y Wang YY Ma L Chen J You XM Zhang ZY Lu SD Li LQ 钟鉴宏 齐鲁楠 | 2014 | 中国癌症防治杂志2014，6，4： | 18 |
| 6 | Antifungal activities and action mechanisms of compounds from Tribulus terrestris L.显示文摘 | Zhang JD Xu Z Cao YB Chen HS Yan L An MM Gao PH Wang Y Jia XM Jiang YY | 2006 | 第二军医大学学报2006，27，5： | 14 |
| 7 | Proline accumulation in rice seedlings exposed to hydroxyl radical stress in relation to antioxidation显示文摘PROLINE(Pro)is an essential amino acid for proteins and free Pro extensively exists in plants.Pro accumulates in plant cells in response to water stress,salinity,low temperature,air pollu-tants,etc.and has been mainly studied for its role in the osmotic adjustment of plants subject-ed to drought and salinity.In addition to acting as a cytoplasmic osmoticum,Pro | Jiang, MY Guo, SC Zhang, XM | 1997 | Chinese Science Bulletin1997，42，10： | 14 |
| 8 | bFGF and TGFβ expression in rat kidneys after ischemic/reperfusional gut injury and its relationship with tissue repair显示文摘INTRODUCTION Intestinal isehemia/rePerfusion(I/R)oeeureommonly in eritieally 111 Patients.It 15 wellreeognized that gutl/R may eause tissue damageand dysfunetion of intestine,and induee | Yang YH Fu XB Sun TZ Jiang LX Gu XM | 2000 | World Journal of Gastroenterology2000，6，1： | 13 |
| 9 | Doxycycline-regulated co-expression of GDNF and TH in PC12 cells.显示文摘 | Wang JJ Zhang T Niu DB Wang K Li KR Xue B Wang XM | 2006 | 中国生物学文摘2006，20，10： | 11 |
| 10 | Effects of HBV gene variations on disease development and antiviral therapy for patients with chronic hepatitis B显示文摘Viral variation may change pathogenicity, escape immunity, lead to persistence infection, and cause drug resistance against antiviral therapy. This study was undertaken to investigate the effects of HBV gene variation on the progression of disease and on the efficacy of antiviral therapy for patients with chronic hepatitis B(CHB). METHODS:Hepatitis B virus (HBV) gene mutational sites were detected using gene chip in selected hepatitis B patients. RESULTS:In the patients HBeAg did not show serologic conversion or HBeAg(-)/anti-HBe(+), but their HBV DNA remained positive 24 weeks after α-interferon therapy, which was associated with mutations of nt1896, nt1814, nt1762 and nt1764. In the patients, that HBV DNA levels decreased or were undetectable, but rebounded later after antiviral therapy by lamivudine was associated with mutations of aa528 and(or) aa552(i.e.YMDD mutation), which resulted in lamivudine-resistance. YMDD mutation was prone to occur 52 weeks after lamivudine therapy in some chronic hepatitis B patients (26.4%). Nt1896 mutation was common in most chronic hepatitis B patients (68.5%). Chronic severe hepatitis, cirrhosis, and primary liver carcinoma were related to the mutations of nt1896, nt1762 and nt1764. CONCLUSIONS:HBV gene mutations could aggravate patient’s condition and affect the efficacy of antiviral therapy. The regular detection of HBV gene mutation is helpful for identification of disease prognosis and adjustment of therapeutic strategy. | Shenzhen Eastlake Hospital, Shenzhen 518020, China (Chen JY) and National Key Laboratory of Virology (Wuhan University) Department of Infectious Diseases, Renmin Hospital, Wuhan University, Wuhan 430060, China(Wang LW, Sun XM and Gong ZJ) | 2005 | Hepatobiliary & Pancreatic Diseases International2005，4，3： | 8 |
| 11 | 磁共振单次扫描多组织对比序列对颈动脉粥样硬化斑块评价的临床初步研究显示文摘目的评价MR 3D单次扫描多组织对比序列(MATCH)定量评价颈动脉血管形态学和定性评价斑块内成分的价值。方法选择超声检查发现颈动脉狭窄>50%且拟行颈动脉内膜剥脱术患者30例,术前分别行MATCH(5min)及MRI常规多序列扫描(T1WI,T2WI,三维时间飞跃和质子密度加权像,18min),扫描范围以颈动脉分叉为中心覆盖全部斑块。用MRI-Plaque View软件分析斑块形态学参数:管腔面积(LA)、管壁面积(WA)、标准化管壁指数(NWI),定性评价斑块内成分,包括斑块内出血(IPH)、斑块钙化(CA)、斑块脂质核心(LRNC)。用Cohen kappa分析2种序列对斑块内成分定性的一致性。结果 30例患者双侧颈动脉入选898个图像层面,MATCH和常规序列LA[(36.27±24.23)mm2 vs(35.72±20.12)mm2,t=1.87,P=0.062],WA[(42.80±20.67)mm2 vs(43.64±24.87)mm2,t=1.74,P=0.082],NWI[(59.21±13.90)vs(59.81±13.96),t=1.80,P=0.072]无显著差异。MATCH与常规序列判断斑块内成分有中到高度的一致性(LRNC:κ值=0.840,CA:κ值=0.802,IPH:κ值=0.773)。结论 MATCH有可能成为评估颈动脉易损斑块成分及斑块破裂危险程度的新方法。 | 杨利新 于薇 Fan ZY Xie YB 王占宏 Bi XM 安靖 张天静 Li DB | 2015 | 中华老年心脑血管病杂志2015，17，11： | 8 |
| 12 | 相关性和一致性:这对相仿概念和测量方法的回顾与阐明(英文)显示文摘一致性(agreement)和相关性(correlation)是两个广泛使用的概念,用来评估变量之间的关联。虽然二者相似且相关,但是它们代表关联完全不同的概念。评估变量之间的一致性假设变量测量的是相同的结构,而在变量测量完全不同的结构时也可以评估它们之间的相关性。这种概念上的差异就要求使用不同的统计方法,并且当评估一致性或相关性时,统计方法根据数据的分布和研究者的兴趣可能会有所不同。例如,Pearson相关性,作为评估连续变量之间相关性的一种普遍测量方法,只有用于符合线性关系的变量时才能提供有用的信息;当用于不符合线性关系的变量时就无法提供准确信息甚至会产生误导。同样地,内部相关性,作为一种评估连续变量之间一致性的常用方法,如果一致性不好的实质正好是研究兴趣所在,那么该测量就不能为研究者提供充分的信息。本报告回顾了一致性和相关性的概念,并讨论了几种常用方法在应用中的差异。 | Liu JY Tang W Chen GQ Lu Y Feng CY Tu XM | 2016 | 上海精神医学2016，28，2： | 6 |
| 13 | Comparison of gene expression between normalcolon mucosa and colon carcinoma by means of messenger RNA differential display显示文摘 | Wang L Lu W Chen YG Zhou XM Gu JR | 1999 | World Journal of Gastroenterology1999，5，6： | 4 |
| 14 | Relationship between polymetallic nodules and submarine hydrothermalism in the Central Pacific Ocean显示文摘THE huge reserves of submarine polymetallic nodules make them an important kind of potentialmineral resources. It has already been discovered that polymetallic nodules are related withsubmarine vollcanogene hydrothermalism. For example, pyroclasts usually occur as coresubstances of the nodules, and large amounts of mineralizing materials such as manganese aredischarged to form ferromanganese oxides along with the submarine vocanogene hydrothermal- | Li, YH Song, HB Li, JC Yao, XM | 1997 | Chinese Science Bulletin1997，42，23： | 4 |
| 15 | Slower cycling of nestin-positive cells in neurosphere culture显示文摘 | Ma BF Liu XM Xie XM Zhang AX Zhang JQ Yu WH Zhang XM Li SN Lahn BT Xiang AP | 2006 | 中国生物学文摘2006，20，5： | 4 |
| 16 | Polymorphisms in DNA base excision repair genes ADPRT and XRCC1 and risk of lung cancer显示文摘 | Zhang XM Miao XP Liang G Hao BT Wang YG Tan W Li Y Guo YL He FC Wei QY Lin DX | 2006 | 中国生物学文摘2006，20，4： | 2 |
| 17 | Ascariasis in China 显示文摘 | Peng WD Zhou XM Crompton DWC | 1998 | Adv Parasitol1998，41，： | 2 |
| 18 | Discovery and significance of Xucun late Proterozoic composite dike swarm in southern Anhui Province显示文摘GEOLOGICALLY, southern Anhui Province, East China, is a part of late Proterozoic collision orogens of the southeast margin of the Yangtze Block. In this region the development of late Proterozoic Fuchuan ophiolite suite and collision granitoids of Xiuning, Xucun and Shexian mark the existence of the intensely tectonic-magmatic events. Recently discovered Xucun | Tang, HF Zhou, XM Zhi, LG | 1997 | Chinese Science Bulletin1997，42，4： | 2 |
| 19 | Enhancement of riboflavin production by overexpression of acetolactate synthase in a pta mutant of Bacillus subtilis显示文摘 | Zhu, YB Chen, X Chen, T Zhao, XM | 2007 | 中国生物学文摘2007，21，11： | 2 |
| 20 | Human intestinal and biliary cryptosporidiosis显示文摘 | Chen XM LaRusso NF | 1999 | World Journal of Gastroenterology1999，5，5： | 2 |
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