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| 1 | Thrombocytopenia after liver transplantation:should we care?显示文摘Transient thrombocytopenia is a common phenomenon after liver transplantation. After liver transplantation(LT), platelet count decreases and reaches a nadir on postoperative days 3-5, with an average reduction in platelet counts of 60%; platelet count recovers to preoperative levels approximately two weeks after LT. The putative mechanisms include haemodilution, decreased platelet production, increased sequestration, medications, infections, thrombosis, or combination of these processes. However, the precise mechanisms remain unclear. The role of platelets in liver transplantation has been highlighted in recent years, and particular attention has been given to their effects beyond hemostasis and thrombosis. Previous studies have demonstrated that perioperative thrombocytopenia causes poor graft regeneration, increases the incidence of postoperative morbidity, and deteriorates the graft and decreases patient survival in both the short and long term after liver transplantation. Platelet therapies to increase perioperative platelet counts, such as thrombopoietin, thrombopoietin receptor agonist, platelet transfusion, splenectomy, and intravenous immunoglobulin treatment might have a potential for improving graft survival, however clinical trials are lacking. Further studies are warranted to detect direct evidence on whether thrombocytopenia is the cause or result of poor-graft function and postoperative complications, and to determine who needs platelet therapies in order to prevent postoperative complications and thus improve post-transplant outcomes. | Kazuhiro Takahashi Shunji Nagai Mohamed Safwan Chen Liang Nobuhiro Ohkohchi | 2018 | World Journal of Gastroenterology2018，24，13： | 5 |
| 2 | Extrahepatic metastasis of hepatocellular carcinoma to the paravertebral muscle:A case report显示文摘Identification of extrahepatic metastases(EHM) of hepatocellular carcinoma(HCC) has been paradoxically increasing due to an increase in the survival of HCC patients. However, metastasis of HCC to the skeletal muscle tissue is extremely rare. We describe a unique case of HCC metastasizing to the paravertebral muscle. A 55-year-old man with a history of hepatitis B cirrhosis underwent partial liver resection with complete removal of HCC. Three months later, a computed tomography(CT) scan showed intrahepatic recurrence. The tumors were treated with yttrium-90 microspheres, transcatheter arterial chemoembolization, and sorafenib. Six months later, a CT scan showed an enhancing lesion of the left paravertebral muscle that on biopsy were consistent with metastatic HCC. The tumor was treated with stereotactic hypo-fractionated imageguided radiation therapy(SHFRT). A follow-up scan 3 mo post-radiotherapy revealed a stable appearance of the paravertebral muscle metastasis. Because of the progression in the intrahepatic tumors, the patient was treated with capecitabine, which was changed to dasatinib 6 mo later. The patient passed away three years after the primary surgical resection. Management of EHM poses an extreme challenge. This is the first case of HCC with EHM to the paravertebral muscle in which stability of disease was achieved using SHFRT. This case highlights the importance of early detection of hepatitis B viral infection and initiation of anti-viral therapy to decrease recurrence of HCC and prevent EHM. | Kazuhiro Takahashi Krishna G Putchakayala Mohamed Safwan Dean Y Kim | 2017 | World Journal of Hepatology2017，9，22： | 2 |
| 3 | Preliminary Study on Tensile and Impact Properties of Kenaf/Bamboo Fiber Reinforced Epoxy Composites显示文摘The application of natural fibers as reinforcement in composite material has increased due to environmental concerns,low cost,degradability and health concerns.The purpose of this study is to identify the best type of bamboo fibers to be used as reinforcement for kenaf(K)/bamboo hybrid composite.There were three types of bamboo fibers evaluated in this study which include bamboo mat(B),bamboo fabric(BF)and bamboo powder(BP).Chemical composition of B,BF,BP and K fibers were analyzed in this study.The effect of different types of bamboo fibers on tensile,impact,and morphological properties were investigated.The B/epoxy composites displayed the highest tensile strength(53.03 MPa)while K/epoxy composite had the highest tensile modulus(4.71 GPa).Scanning electron micrographs of B/epoxy composites displayed better fiber/matrix interfacial bonding in comparison to other studied composites.Results showed that impact strength of BF-based composite was highest(45.70 J/m).In conclusion,the tensile strength of B/epoxy composite is superior to the other bamboo reinforced composites and will be further evaluated in the next study. | Ahmad Safwan Mohammad Jawaid Mohamed T.H.Sultan Azman Hassan | 2018 | Journal of Renewable Materials2018，6，5： | 2 |
| 4 | routine internal sphincterotomy with hemorrhoideetomy for third and fourth degree hemorrhoids greatly improve the outcome显示文摘 | Safwan A Taha | 2003 | LJGE2003，4，1： | 1 |
| 5 | Impact of Autonomic Dysfunction on Inflammatory Bowel Disease显示文摘 | Ashwin N. Ananthakrishnan Mazen Issa Alexandru Barboi Safwan Jaradeh Yelena Zadvornova Sue Skaros Kathryn Johnson Mary F. Otterson David G. Binion | 2010 | Journal of Clinical Gastroenterology2010，，： | 1 |
| 6 | Swallow-related cerebral cortical activity maps are not specific to deglutition显示文摘 | Kern M Rasmus B Safwan J | 2001 | Am J Physiol Gastrointest Liver Physiol2001，280，4： | 1 |
| 7 | Variable coefficient equations of the Kadomtsev–Petviashvili hierarchy: multiple soliton solutions and singular multiple soliton solutions显示文摘 | H M Jaradat Safwan Al-Shara Fadi Awawdeh Marwan Alquran | 2012 | Physica Scripta2012，，3： | 1 |
| 8 | Modulation Classification based on ModifiedKolmogorov- Smimov Test显示文摘 | Ali Waqar Azim Syed Safwan Khalid ShafayatAbrar | 2013 | Emerging Technologies(ICET)2013，，9： | 1 |
| 9 | Angiotensin II Activation of mTOR Results in Tubulointerstitial Fibrosis through Loss of N-Cadherin显示文摘 | Whaley-connell Adam Habibi Javad Panfili Zachary Hayden Melvin R Bagree Sarika Nistala Ravi Hyder Safwan Krueger Bennett Demarco Vincent Pulakat Lakshmi Ferrario Carlos M Parrish Alan Sowers James R | 2011 | EN2011，，2： | 1 |
| 10 | Deformation mechanism in asphaltic concrete 显示文摘 | Safwan A Khedr | 1986 | Journal of Transportation Engineering1986，112，1： | 1 |
| 11 | Swallow-related cerebra cortical activity maps are not specific to deglutition显示文摘 | Kern M Rasmus B Safwan J | 2001 | Am J Physiol Gastrointest Liver Physiol2001，280，： | 1 |
| 12 | Cerebral cortical representation of reflexive and volitional swallowing in humans显示文摘 | Safwan J Ronald C | 2001 | Am J Physiol Gastrointest Liver Physiol2001，280，： | 1 |
| 13 | Digital art and design显示文摘 | BATIHA Khaled AL SALAIMEH Safwan BESOUL Khaldoun A A | 2006 | Leonardo Journal of Sciences2006，，3： | 1 |
| 14 | Design and evaluation of effervescent fl oating tablets based on hydroxyethyl cellulose and sodium alginate using pentoxifylline as a model drug显示文摘 | Safwan AR Paul A Amal A | 2015 | Drug Des Devel Ther2015，9，2： | 1 |
| 15 | Digital art and design显示文摘 | BATIHA Khale SALAIMEH Safwan A1 BESOUL Khaldoun A A | 2006 | Leonardo Journal of Sciences2006，，3： | 1 |
| 16 | Sympa-thetic skin response in patients with erectile dysfunction 显示文摘 | CONSUELO V A JESUS F G SAFWAN E | 2009 | BJU international2009，104，11： | 1 |
| 17 | Wound dehiscence with continuous versus interrupted mass closure of transverse incisions in children with absorbable suture:a randomized controlled trial显示文摘Introduction Numerous meta-analyses done on adults suggest superiority of continuous mass closure technique,but any such study does not exist for the pediatric age group.The results in adults cannot be applied to pediatrics because of numerous physiologic and anatomic differences.Methods This is a single-blinded,randomized controlled trial,1:1 parallel groups,that compares the frequency of dehiscence between the interrupted and continuous mass closure techniques for transverse incisions in pediatric patients.The age range was from birth to 12 years.We sampled 350 patients undergoing emergency or elective exploratory laparotomies in our pediatric surgery unit.Blocked randomization was used and only the patients remained blinded during the intervention.One group was closed with interrupted mass closure(group A)and the other group with continuous mass closure technique(group B).We had to drop 50 patients for not meeting the inclusion criteria.results The wound dehiscence rate for group A was 1.34%(4 patients)and for group B was 3.0%(9 patients).Significance was calculated usingχ^(2)(p<0.156).The global wound dehiscence rate was 4.34%(13 patients).The maximum number of patients dehisced on the fifth postoperative day,while the range was 4-11 days.The only statistically significant confounding factor was wound classification(p<0.002).Discussion Statistically there is no significant difference between interrupted and continuous mass closures techniques in terms of wound dehiscence.The dirty wounds are at a maximum risk of developing wound dehiscence irrespective of the technique used.We need to strictly adhere to the basic principles of closure especially when dealing with dirty wounds.trial registration number TCTR20150318001. | Safwan Khan Muhammad Saleem Nabila Talat | 2019 | World Journal of Pediatric Surgery2019，2，2： | 0 |
| 18 | Combined forest and soil management after a catastrophic event显示文摘At the end of October 2018,a storm of unprecedented strength severely damaged the forests of the eastern sector of the Italian Alps.The affected forest area covers 42,500 ha.The president of one of the damaged regions asked for help from the University of Padua.After eight months of discussion,the authors of this article wrote a consensus text.The sometimes asper debate brought to light some crucial aspects:1)even experienced specialists may have various opinions based on scientific knowledge that lead to conflicting proposals for action.For some of them there is evidence that to restore a destroyed natural environment it is more judicious to do nothing;2)the soil corresponds to a living structure and every ecosystem’s management should be based on it;3)faced with a catastrophe,people and politicians find themselves unarmed,also because they rarely have the scientific background to understand natural processes.Yet politicians are the only persons who make the key decisions that drive the economy in play and therefore determine the near future of our planet.This article is an attempt to respond directly to the governor of a region who formally and prudently asked a university department called'Land,Environment,Agriculture and Forestry'for help before taking decisions;4)the authors also propose an artistic interpretation of facts(uncontrolled storm)and conclusions(listen to the soil).Briefly,the authors identify the soil as an indispensable source for the renewal of the destroyed forest,give indications on how to prepare a map of the soils of the damaged region,and suggest to anchor on this soil map a series of silvicultural and soil management actions that will promote the soil conservation and the faster recovery of the natural dynamic stability and resilience. | Augusto ZANELLA Jean-Francois PONGE Anna ANDREETTA Michael AUBERT Nicolas BERNIER Eleonora BONIFACIO Karine BONNEVAL Cristian BOLZONELLA Oleg CHERTOV Edoardo A.C.COSTANTINI Maria DE NOBILI Silvia FUSARO Raffaello GIANNINI Pascal JUNOD Klaus KATZENSTEINER Jolantha KWIATKOWSK-MALINA Roberto MENARDI Lingzi MO Safwan MOHAMMAD Annik SCHNITZLER Adriano SOFO Dylan TATTI Herbert HAGER | 2020 | Journal of Mountain Science2020，17，10： | 0 |
| 19 | Dynamic ^(18)F-fluorodeoxyglucose positron emission tomography/CT in hibernoma: enhanced tracer uptake mimicking liposarcoma显示文摘We report on two cases of patients with fat-equivalent masses in computed tomography(CT),referred to our department for dynamic positron emission tomography/CT(dPET/CT)with18F-fluorodeoxyglucose(18FFDG)in order to investigate their dignity.Both qualitative and quantitative information,as derived from dPET/CTs,couldn’t exclude a high-grade liposarcoma:Visual evaluation,revealed a large hypermetabolic focus of intense18F-FDG uptake in each patient(average SUVs 8.3 and 11.3).Regression-based parametric imaging demonstrated an enhanced distribution volume,which correlates to perfusion,and a high phosphorylation rate that correlates to cell viability.Kinetic analysis,based on a two-tissue compartment model demonstrated an enhanced FDG transport k1and an enhanced phosphorylation rate k3.A non-compartmental approach based on fractal dimension revealed also enhanced values.However,final diagnosis was based on biopsy,which revealed hibernoma,a benign brown fat tumor.Brown adipose contains increased numbers of mitochondria and a high-rate of glucose metabolism.Therefore,they have increased FDG uptake.The evaluation of lipomatous lesions on CT,with high FDG uptake,should include the possibility of hibernoma as a differential diagnosis. | Christos Sachpekidis Safwan Roumia Matthias Schwarzbach Antonia Dimitrakopoulou-Strauss | 2013 | World Journal of Radiology2013，5，12： | 0 |
| 20 | Rabi oscillation generation in the microring resonator system with double-series ring resonators显示文摘In this paper, a microring resonator(MRR) system using double-series ring resonators is proposed to generate and investigate the Rabi oscillations. The system is made up of silicon-on-insulator and attached to bus waveguide which is used as propagation and oscillation medium. The scattering matrix method is employed to determine the output signal intensity which acts as the input source between two-level Rabi oscillation states, where the increase of Rabi oscillation frequency with time is obtained at the resonant state. The population probability of the excited state is higher and unstable at the optical resonant state due to the nonlinear spontaneous emission process. The enhanced spontaneous emission can be managed by the atom(photon) excitation, which can be useful for atomic related sensors and single-photon source applications. | Ahmad Fakhrurrazi Ahmad Noorden Kashif Chaudhary Mahdi Bahadoran Muhammad Safwan Aziz Muhammad Arif Jalil Ong Chee Tiong Jalil Ali Preecha Yupapin | 2015 | Optoelectronics Letters2015，11，5： | 0 |
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