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| 1 | Procalcitonin and intestinal ischemia:A review of the literature显示文摘Intestinal ischemia is common after emergency gastrointestinal or cardiovascular surgery.At present,there are no diagnostic tools for the early diagnosis of intestinal ischemia.In the last decade,procalcitonin(PCT)has been suggested as a marker of this condition.Here,we review the use of PCT as a diagnostic tool for intestinal ischemia.Two reviewers independently searched the Pub Med and EMBASE databases for articles on intestinal ischemia and PCT.They then considered(1)the criteria applicable to preclinical and clinicaldata;and(2)PCT’s predictive value in the diagnosis of intestinal ischemia.Article quality was rated according to the STAndards for Reporting of Diagnostic accuracy.Between 1993 and 2014,seven studies(including two preclinical studies and five clinical studies)dealt with the use of PCT to diagnose intestinal ischemia.Procalcitonin’s sensitivity,specificity,positive predictive value and negative predictive value ranged between 72%and 100%;68%and 91%;27%and 90%and 81%and 100%,respectively.The area under the receiver operating characteristic curve ranged from 0.77 to 0.92.In view of the preclinical and clinical data,we consider that PCT can be used in daily practice as a tool for diagnosing intestinal ischemia. | Cyril Cosse Charles Sabbagh Sad Kamel Antoine Galmiche Jean-Marc Regimbeau | 2014 | World Journal of Gastroenterology2014，20，47： | 9 |
| 2 | Noncontrast-enhanced MRI-based Noninvasive Score for Portal Hypertension(CHESS1802):An International Multicenter Study显示文摘Background and Aims:This study aimed to determine the performance of the non-invasive score using noncontrastenhanced MRI(CHESS-DIS score)for detecting portal hy-pertension in cirrhosis.Methods:In this international multicenter,diagnostic study(ClinicalTrials.gov,NCT03766880),patients with cirrhosis who had hepatic venous pressure gradient(HVPG)measurement and noncontrast-enhanced MRI were prospectively recruited from four university hospitals in China(n=4)and Turkey(n=1)between December 2018 and April 2019.A cohort of patients was retrospectively recruited from a university hospital in Italy between March 2015 and November 2017.After segmentation of the liver on fat-suppressed T1-weighted MRI maps,CHESS-DIS score was calculated automatically by an in-house developed code based on the quantification of liver surface nodularity.Results:A total of 149 patients were included,of which 124 were from four Chinese hospitals(training cohort)and 25 were from two international hospitals(validation cohort).A positive correlation between CHESS-DIS score and HVPG was found with the correlation coefficients of 0.36(p<0.0001)and 0.55(p<0.01)for the training and validation cohorts,respectively.The area under the receiver operating characteristic curve of CHESS-DIS score in detection of clinically significant portal hypertension(CSPH)was 0.81 and 0.9 in the training and validation cohorts,respectively.The intra-class correlation coefficients for assessing the inter-and intra-observer agreement were 0.846 and 0.841,respectively.Conclusions:A non-invasive score using noncontrast-enhanced MRI was developed and proved to be significantly correlated with invasive HVPG.Besides,this score could be used to detect CSPH in patients with cirrhosis. | Yanna Liu Tianyu Tang NecatiÖrmeci Yifei Huang Jitao Wang Xiaoguo Li Zhiwei Li Weimin An Dengxiang Liu Chunqing Zhang Changchun Liu Jinqiang Liu Chuan Liu Guangchuan Wang Cristina Mosconi Alberta Cappelli Antonio Bruno Seray Akçalar EmrecanÇelebioğlu EvrenÜstüner Sadık Bilgiç Zeynep Ellik ÖzgünÖmer Asiller Lei Li Haijun Zhang Ning Kang Dan Xu Ruiling He Yan Wang Yang Bu Ye Gu Shenghong Ju Rita Golfieri Xiaolong Qi | 2021 | Journal of Clinical and Translational Hepatology2021，9，6： | 3 |
| 3 | Prevalence of microscopic colitis in patients with diarrhea of unknown etiology in Turkey显示文摘AIM: To investigate the prevalence and demography of microscopic colitis in patients with diarrhea of unknown etiology and normal colonoscopy in Turkey. METHODS: Between March, 1998 to July, 2005, 129 patients with chronic non-bloody diarrhea of unexplained etiology who had undergone full colonoscopy with no obvious abnormalities were included in the study. Two biopsies were obtained from all colonic segments and terminal ileum for diagnosis of microscopic colitis. On histopathologic examination, criteria for lymphocytic colitis (intraepithelial lymphocyte ≥ 20 per 100 intercryptal epithelial cells, change in surface epithelium, mononuclear infiltration of the lamina propria) and collagenous colitis (subepithelial collagen band thickness ≥ 10 μm) were explored. RESULTS: Lymphocytic colitis was diagnosed in 12 (9%) patients (Female/Male: 7/5, mean age: 45 year, range: 27-63) and collagenous colitis was diagnosed in only 3 (2.5%) patients (all female, mean age: 60 years, range: 54-65).CONCLUSION: Biopsy of Turkish patients with the diagnosis of chronic non-bloody diarrhea of unexplained etiology and normal colonoscopic findings will reveal microscopic colitis in approximately 10% of the patients. Lymphocytic colitis is 4 times more frequent than collagenous colitis in these patients. | Levent Erdem Sadιk Yιldιrιm Nihat Akbayιr Banu Yιlmaz Necati Yenice Orhan Sami Gültekin nder Peker | 2008 | World Journal of Gastroenterology2008，14，27： | 2 |
| 4 | Status of groundwater arsenic contamination in all 17 blocks of Nadia district in the state of West Bengal, India: A 23-year study report显示文摘 | Mohammad Mahmudur Rahman Debapriya Mondal Bhaskar Das Mrinal Kumar Sengupta Sad Ahamed M. Amir Hossain Alok Chandra Samal Kshitish Chandra Saha Subhash Chandra Mukherjee Rathindra Nath Dutta Dipankar Chakraborti | 2013 | Journal of Hydrology2013，，： | 2 |
| 5 | The expanding universe of T-cell subsets: Th1, Th2 and more显示文摘 | Mosmann T R Sad S | 1996 | Immunol Today1996，17，： | 1 |
| 6 | Cytotoxicity and weak CD40 ligand expression of CD8^+ type 2 cytotoxie T cells restricts their potential B cell helper activity显示文摘 | Sad S Krishnan L Bleackley RC | 1997 | Eur J Immunol1997，27，： | 1 |
| 7 | Symbiotic Gap and Semigap Solitons in Bose-Einstein Condensates显示文摘 | Adhikari Sad han Kv Malorned Boris A | 2008 | Phys Rev A2008，77，02： | 1 |
| 8 | The expanding universe of T cell subsets :Th1 ,Th2 and more显示文摘 | Mosmann FR Sad S | 1996 | Immunol Today1996，，17： | 1 |
| 9 | The expanding universe of T-cel subsets: Th1, Th2 and mere 显示文摘 | Monsmann TR Sad S | 1996 | Immunol Today1996，17，5： | 1 |
| 10 | The expanding universe of T-cell subsets:Th1,Th2 and more显示文摘 | MOSMANN T R SAD S | 1996 | Immunol Today1996，17，3： | 1 |
| 11 | Function of CD8 T cell subsets secreting different cytokine patterns显示文摘 | Mosmann TR LiL Sad S | 1997 | Immunol1997，9，： | 1 |
| 12 | Two-component Gap Solitons with Linear Interconversion显示文摘 | J Adhikari Sad han K Malorned Boris A | 2009 | Phys Rev A2009，79，01： | 1 |
| 13 | The expanding universe of T-cell subsets:Thl,Th2and more显示文摘 | MOSMANN T R SAD S | 1996 | Immunology Today1996，17，3： | 1 |
| 14 | The expending universe of T-cell subsets:Th1,Th2 and more显示文摘 | Sad S | 1996 | Immunol Today1996，17，3： | 1 |
| 15 | CD8Tc1 and Tc2 cells secrete distinct cytokine patterns in vitro and in vivo but induce similar inflammatory reactions显示文摘 | Sad S Kagi D | 1997 | J Immunol1997，158，9： | 1 |
| 16 | Gap Solitons in Superfluid Boson-fermion Mixtures显示文摘 | Adhikari Sad han K | 2007 | Phys Rev A2007，76，04： | 1 |
| 17 | Function of CD8 T-cell subsets secreting different cytokine patterns 显示文摘 | Mosmann TR Li L Sad S | 1997 | Semin Immunol1997，9，2： | 1 |
| 18 | The effects of grada- tion and admixture on the pumice lightweight aggre- gate concrete 显示文摘 | Sad D Pasamehmetoglu A G | 2005 | Cement and Concrete Research2005，35，： | 1 |
| 19 | The expanding universe of T- cell subsets:Th1 ,Th2and more 显示文摘 | Sad A | 1996 | Immunol Today1996，17，3： | 1 |
| 20 | Agricultur- al waste matorial as potential adsorbent for sequestering heavy metal ions from aque- ous solutions a review 显示文摘 | Sad D Mahajan C Kaur M P | 2008 | Bioresource Technology2008，99，： | 1 |
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