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| 1 | In situ simultaneous determination of trace elements,U-Pb and Lu-Hf isotopes in zircon and baddeleyite显示文摘This paper describes a combined method of simultaneously measuring U-Pb and Lu-Hf isotopes as well as trace elements in Phalaborwa baddeleyite and 91500, GJ-1, TEMORA-1 and SK10-2 zircons by means of Neptune MC-ICPMS and Agilent Q-ICPMS connected to a 193 nm excimer laser ablation system. Material ablated by laser was carried in different proportions into Q-ICPMS for U-Pb isotopic and trace elemental and MC-ICPMS for Lu-Hf isotopic compositions. Experiments indicate that different proportions of ablated material for the Q-ICPMS and MC-ICPMS (6:4, 5:5 and 4:6 respectively) do not show any bias for the zircon/baddeleyite U-Pb age, Lu-Hf isotope and trace elemental compositions within ana-lytical errors. Using 40―60 μm spot size, the obtained U-Pb ages of Phalaborwa baddeleyite, 91500, GJ-1, TEMORA and SK10-2 zircons are 2065±15 (2σ, n=20), 1063±6 (2σ, n=19), 613±6 (2σ, n=20), 416±5 (2σ, n=20) and 32.6±0.5 (2σ, n=20) Ma, respectively. The 176Hf/177Hf ratios are 0.281231±24 (2SD, n=20), 0.282310±35 (2SD, n=19), 0.282028±34 (2SD, n=20), 0.282687±34 (2SD, n=20) and 0.282752±53 (2SD, n=20), respectively. The obtained trace elemental compositions are identical to the reference values. Therefore, this kind of technique makes it possible to simultaneously obtain the U-Pb age, Lu-Hf iso-topes and trace elemental compositions of zircon and baddeleyite, which could be an important tool in solving problems in earth sciences. | XIE LieWen ZHANG YanBin ZHANG HuiHuang SUN JingFeng WU FuYuan | 2008 | Chinese Science Bulletin2008，53，10： | 97 |
| 2 | Processing of advanced thermoelectric materials显示文摘Last two decades have witnessed significant progress in thermoelectric research,to which materials processing has crucial contributions.Compared with traditional zone-melting method used for fabricating bismuth telluride alloys,new powder-based processes have more freedom for manipulating nanostructures and nanocomposites.Thermoelectric performance enhancement is realized in most thermoelectric materials by introducing fine-grained and nano-composite structures with accurately controlled compositions.This review gives a comprehensive summary on the processing aspects of thermoelectric materials with three focuses on the powder synthesis,advanced sintering process and the formation of nano structures in bulk materials. | LI JingFeng PAN Yu WU ChaoFeng SUN FuHua WEI TianRan | 2017 | Science China(Technological Sciences)2017，60，9： | 13 |
| 3 | Velvet antler polypeptide is able to induce differentiation of neural stem cells towards neurons in vitro显示文摘OBJECTIVE: To investigate the neural differentiation capacity of water extraction of velvet antler.METHODS: Velvet antler(Cervus Nippon Temminck) polypeptide(VAP) was used to differentiate neural stem cells(NSCs) towards neurons in the study. Firstly, we obtain the polypeptides of VAP by water extraction. Secondly, we observed the morphology, assayed the factors in the media by enzyme-linked immunosorbent assay, and detected the special neural molecules by immuno fl uorescence staining. NSCs were cultured on the cell climbing film. After neuronal differentiation, differentiated NSCs were mounted for immunocytochemistry with immunofluorescence technique.RESULTS: The differentiating cells look like neuron,some special factors, such as Glial cell line-derived neurotrophic factor, nerve growth factor, in the media can be detected while differentiated neuron-like cells can express the special neural molecules.CONCLUSION: Differentiation of NSCs towards neurons can be induced by velvet antler polypeptide. | Zhang Lihong Zhuang Zhihong Sun Yanan Ma Shuhua Yang Weifeng Lei Hongtao Zuo Junling Ouyang Jingfeng Wang Yi | 2017 | Journal of Traditional Chinese Medicine2017，37，3： | 8 |
| 4 | Total body irradiation of donors can alter the course of tolerance and induce acute rejection in a spontaneous tolerance rat liver transplantation model显示文摘Liver transplantation is an established therapy for end-stage liver diseases. Graft rejection occurs unless the recipient receives immunosuppression after transplantation. This study aimed to explore the mechanism of acute rejection of liver allografts in rats pre-treated with total body irradiation to eliminate passenger lymphocytes and to define the role of CD4 + CD25 + regulatory T cells in the induction of immunotolerance in the recipient. Male Lewis rats were used as donors and male DA rats were recipients. Rats were randomly assigned to the following four groups: control group, homogeneity liver transplantation group, idio-immunotolerance group and acute rejection group. After transplantation, the survival time of each group, serum alanine aminotransferase, total bilirubin levels, number of Foxp3 + CD4 + CD25 + regulatory T cells, expression of glucocorticoid-induced tumor necrosis factor receptor on T cell subgroups, histopathology of the hepatic graft and spleen cytotoxic T lymphocyte lytic activity were measured. In the acute rejection group, where donors were preconditioned with total body irradiation before liver transplantation, all recipients died between day 17 and day 21. On day 14, serum alanine aminotransferase increased signifi- cantly to (459.2±76.9) U L -1 , total bilirubin increased to (124.1±33.7) μmol L -1 (P<0.05) and the ratio of Foxp3 + CD4 + CD25 + regulatory T cells decreased significantly to 1.50%±0.50% (P<0.05) compared with the other groups. Analysis of the T cell subpopulations in the acute rejection group varied from the other groups. Histological analysis showed typical changes of acute rejection in the acute rejection group only. Preconditioning of the donors with total body irradiation eliminated passenger lymphocytes of the liver graft, and thus affected the course of tolerance and induced acute rejection after liver transplantation. | ZHANG YeWei ZHAO HeWei BO Lin YANG YinXue LU Xiang SUN JingFeng WEN JianFei HE Xia YIN GuoWen | 2012 | Science China(Life Sciences)2012，55，9： | 4 |
| 5 | Chinese expert consensus on conversion therapy for hepatocellular carcinoma(2021 edition)显示文摘Recent advances in systemic and locoregional treatments for patients with unresectable or advanced hepatocellular carcinoma(HCC)have resulted in improved response rates.This has provided an opportunity for selected patients with initially unresectable HCC to achieve adequate tumor downstaging to undergo surgical resection,a‘conversion therapy’strategy.However,conversion therapy is a new approach to the treatment of HCC and its practice and treatment protocols are still being developed.Review the evidence for conversion therapy in HCC and develop consensus statements to guide clinical practice.Evidence review:Many research centers in China have accumulated significant experience implementing HCC conversion therapy.Preliminary findings and data have shown that conversion therapy represents an important strategy to maximize the survival of selected patients with intermediate stage to advanced HCC;however,there are still many urgent clinical and scientific challenges for this therapeutic strategy and its related fields.In order to summarize and learn from past experience and review current challenges,the Chinese Expert Consensus on Conversion Therapy for Hepatocellular Carcinoma(2021 Edition)was developed based on a review of preliminary experience and clinical data from Chinese and non-Chinese studies in this field and combined with recommendations for clinical practice.Sixteen consensus statements on the implementation of conversion therapy for HCC were developed.The statements generated in this review are based on a review of clinical evidence and real clinical experience and will help guide future progress in conversion therapy for patients with HCC. | Hui-Chuan Sun Jian Zhou Zheng Wang Xiufeng Liu Qing Xie Weidong Jia Ming Zhao Xinyu Bi Gong Li Xueli Bai Yuan Ji Li Xu Xiao-Dong Zhu Dousheng Bai Yajin Chen Yongjun Chen Chaoliu Dai Rongping Guo Wenzhi Guo Chunyi Hao Tao Huang Zhiyong Huang Deyu Li Gang Li Tao Li Xiangcheng Li Guangming Li Xiao Liang Jingfeng Liu Fubao Liu Shichun Lu Zheng Lu Weifu Lv Yilei Mao Guoliang Shao Yinghong Shi Tianqiang Song Guang Tan Yunqiang Tang Kaishan Tao Chidan Wan Guangyi Wang Lu Wang Shunxiang Wang Tianfu Wen Baocai Xing Bangde Xiang Sheng Yan Dinghua Yang Guowen Yin Tao Yin Zhenyu Yin Zhengping Yu Bixiang Zhang Jialin Zhang Shuijun Zhang Ti Zhang Yamin Zhang Yubao Zhang Aibin Zhang Haitao Zhao Ledu Zhou Wu Zhang Zhenyu Zhu Shukui Qin Feng Shen Xiujun Cai Gaojun Teng Jianqiang Cai Minshan Chen Qiang Li Lianxin Liu Weilin Wang Tingbo Liang Jiahong Dong Xiaoping Chen Xuehao Wang Shusen Zheng Jia Fan 无 | 2022 | Hepatobiliary Surgery and Nutrition2022，11，2： | 4 |
| 6 | Potential effect of sedimentary iron-phosphorus accumulation on frequent algal bloom in the Pearl River Estuary显示文摘Based on laboratory culture of harmful alga on iron and phosphorus uptake, and the study of accu-mulation of iron-phosphorus in cores and release of iron and phosphorus from surficial sediments collected in the Pearl River Estuary, the reasons of the high frequency of phytoplankton bloom therein are discussed. The results show that Fe starvation can make algal growth rate slow down and the peak of cell number decrease. Fe and P contents in algal cell bear a significant correlation and the molar ratio of P:Fe is ~356:1, suggesting that algal uptake of Fe and P is synergistic. Total Fe and total P in sediments are positively correlated and Fe-P is the main species of inorganic sedimentary P. Through continuous leaching with agitation, 34.26%―80.21% of exchangeable P and 4.04%―22.52% of ex-changeable Fe are released from surficial sediments, implying that the accumulation of Fe-P in sedi-ments is available for providing nutrients (P and essential Fe) for the demand of phytoplankton bloom. These factors might be responsible for a higher frequency of red tides than other marine regions. | WENG HuanXin SUN XiangWei CHEN JingFeng CHEN JianFang CHEN LiHong CHEN XiangHua QIN YaChao | 2007 | Science China Earth Sciences2007，50，3： | 3 |
| 7 | Spatial distribution characteristics of bacterial community structure and gene abundance in sediments of the Bohai Sea显示文摘This study investigated differences in the community structure and environmental responses of the bacterial community in sediments of the Bohai Sea.Illumina high-throughput sequencing technology and real-time PCR were used to assay the bacterial 16S rRNA genes in the surface sediments of 13 sampling stations in the Bohai Sea.The results showed that sediments at the majority of the 13 sampling stations were contaminated by heavy metal mercury.The main phyla of bacteria recorded included Proteobacteria(52.92%),Bacteroidetes(11.76%),Planctomycetes(7.39%),Acidobacteria(6.53%)and Chloroflexi(4.97%).The genus with the highest relative abundance was Desulfobulbus(4.99%),which was the dominant genus at most sampling stations,followed by Lutimonas and Halioglobus.The main factors influencing bacterial community structure were total organic carbon,followed by depth and total phosphorus.The content of lead,cadmium,chromium,copper and zinc had a consistent effect on community structure.Arsenic showed a negative correlation with bacterial community structure in most samples,while the impact of mercury on community structure was not significant.The bacterial community in sediment samples from the Bohai Sea was rich in diversity and displayed an increase in diversity from high to low latitudes.The data indicated that the Bohai Sea had abundant microbial resources and was rich in bacteria with the potential to metabolize many types of pollutants. | Quanrui Chen Jingfeng Fan Jie Su Hongxia Ming Zhihao Sun Mengfei Li Xiaohui Zhao Yantao Wang Yingxue Zhang Huizhen Zhang Yuan Jin Xiaowan Ma Bin Wang | 2020 | Acta Oceanologica Sinica2020，39，2： | 2 |
| 8 | Mining Typical Treatment Duration Patterns for Rational Drug Use from Electronic Medical Records显示文摘Rational drug use requires that patients receive medications for an adequate period of time.The adequate duration time of medications not only improve the therapeutic effect of medicines,but also reduce the side effects and adverse reactions of medicines.This paper proposes a data-driven method to mine typical treatment duration patterns for rational drug use from electronic medical records (EMRs).Firstly,a quintuple is defined to describe drug use duration statistics (DUDS) for each drug and treatment record is further represented with DUDS vector (DUDSV).Next a similarity measure method is adopted to compute the similarity between treatment records.Meanwhile,a clustering algorithm is used to cluster all patient treatment records to extract typical treatment duration patterns including typical drug sets,effective drug use day sets,and the DUDSs of each typical drug.Then the extracted typical treatment duration patterns are evaluated and annotated based on patients' demographic information,disease severity scores,treatment outcome and diagnostic information.Finally,a real-world EMR dataset is performed to indicate that the approach we proposed can effectively mine typical treatment duration patterns from EMRs and recommend the appropriate treatment regimens for patients based on their admission information. | Jingfeng Chen Chonghui Guo Leilei Sun Menglin Lu | 2019 | Journal of Systems Science and Systems Engineering2019，28，5： | 2 |
| 9 | Detection and estimation of mixed paddy rice cropping patterns with MODIS data显示文摘 | Dailiang Peng Alfredo R. Huete Jingfeng Huang Fuming Wang Huasheng Sun | 2010 | International Journal of Applied Earth Observations and Geoinformation2010，，1： | 2 |
| 10 | Effects of Epstein-Barr virus infection on the development of multiple myeloma after liver transplantation显示文摘Reduced cellular immune function in patients after liver transplantation easily results in many types of viral infections,such as Epstein-Barr virus.Epstein-Barr virus is a γ-herpesvirus and is related to many malignant diseases,especially epithelial and lymph tumors.The abnormal interaction of cluster of differentiation 40 with cluster of differentiation 40 ligand and expression of cluster of differentiation 40 ligand are considered closely related to the development of myeloma cells.This study explored the influence and mechanism of Epstein-Barr virus infection on the phenotype and biological behavior of myeloma cells after liver transplantation.Flow cytometry was used to detect coexpression of cluster of differentiation 40 and cluster of differentiation 40 ligand in 10 samples of freshly isolated multiple myeloma cells.Cluster of differentiation 40 and cluster of differentiation 40 ligand were coexpressed in sample Nos.5,8,9,and 10,particularly in sample No.5.Western blot analysis was used to detect the expression of the Epstein-Barr virus antigens latent membrane protein 1 and Epstein-Barr virus nuclear antigen 2 in the multiple myeloma cell line RPMI 8226 infected with Epstein-Barr virus.The antigen expression indicated that Epstein-Barr virus can infect multiple myeloma virus cells in vitro.Reverse transcription-polymerase chain reaction revealed upregulated expression of cluster of differentiation 40 ligand on the infected RPMI 8226 cells,which may be involved in the anti-apoptosis activity of the infected cells.Confocal microscopy showed that pairs of molecules of cluster of differentiation 40,cluster of differentiation 40 ligand,and latent membrane protein 1 were colocalized on the surface of the infected cells.CXC chemokine receptor 4 was upregulated on the RPMI 8226 cells after Epstein-Barr virus infection.The migratory ability of the infected cells improved in the presence of the chemokine stromal cell-derived factor-1α.Anti-apoptosis and migration are known important biological characteristics of malignant cells.Our results indicate the involvement of Epstein-Barr virus in the origin and development of multiple myeloma.The risk of multiple myeloma increases when Epstein-Barr virus infects B cells in the germinal center,which may result in an anti-apoptosis effect of B cells and an improved ability to migrate from the germinal center to peripheral blood. | ZHANG YeWei ZHAO HeWei HE Xia ZHENG SuWen WANG TaiHong YAN DongLiang SUN JingFeng LU Xiang WEN JianFei LAU Wan Yee | 2012 | Science China(Life Sciences)2012，55，8： | 2 |
| 11 | The template-assisted zinc ion incorporation in SAPO-34 and the enhanced ethylene selectivity in MTO reaction显示文摘The SAPO-34 catalyst was fine-tuned with zinc cations through a straightforward template-assisted ion incorporation (TH) process, without the necessary template pre-removal and the preparation of NH4- SAPO-34 intermediate, which is more facile, efficient and cost-effective than the conventional ion exchange process. The template-assisted zinc cations incorporated SAPO-34 catalysts were characterized by XRD, XRF, N2 adsorption-desorption, XPS, SEM, EDX,NMR, respectively. Enhanced selectivity to ethylene and ratio of ethylene to propylene in MTO reaction are observed over the zinc cations modified SAPO-34 catalysts, due to the facilitated formation of lower methylbenzenes that favour the ethylene gen eration, as well as the increased diffusion hindrance originated from the zinc cations incorporation and the facil让ated generation of aromatics compound. | Jiawei Zhong Jingfeng Han Yingxu Wei Shutao Xu Tantan Sun Xinwen Guo Chunshan Song Zhongmin Liu | 2019 | Journal of Energy Chemistry2019，28，5： | 2 |
| 12 | Transpacific transport and evolution of the optical properties of Asian dust显示文摘 | Zhaoyan Liu T. Duncan Fairlie Itsushi Uno Jingfeng Huang Dong Wu Ali Omar Jayanta Kar Mark Vaughan Raymond Rogers David Winker Charles Trepte Yongxiang Hu Wenbo Sun Bing Lin Anning Cheng | 2013 | Journal of Quantitative Spectroscopy and Radiative Transfer2013，，： | 1 |
| 13 | Factors to Assess Self-Archiving in Institutional Repositories显示文摘 | Xia Jingfeng Sun Li | 2007 | Serials Review2007，，2： | 1 |
| 14 | A rapid quantitative method for polysaccharides in green tea and oolong tea显示文摘 | Dongfeng Wang Xiaoling Zhou Lei Li Yangfeng Hou Jipeng Sun Jingfeng Wang | 2008 | European Food Research and Technology2008，，4： | 1 |
| 15 | Photochemical hydrogen production with molecular devices comprising a zinc porphyrin and a cobaloxime catalyst显示文摘Two new noble-metal-free molecular devices,[{Co(dmgH) 2 Cl}{Zn(PyTPP)}](1,dmgH = dimethyloxime,PyTPP = 5-(4pyridyl)-10,15,20-triphenylporphyrin) and [{Co(dmgH) 2 Cl}{Zn(apPyTPP)}](2,apPyTPP = 5-[4-(isonicotinamidyl)phenyl]10,15,20-triphenylporphyrin),for light-driven hydrogen generation were prepared and spectroscopically characterized.The zinc porphyrin photosensitizer and the Co III-based catalyst unit are linked by axial coordination of a pyridyl group in the periphery of zinc-porphyrin to the cobalt centre of catalyst with different lengths of bridges.The apparent fluorescence quenching and lifetime decays of 1 and 2 were observed in comparison with their reference chromophores,Zn(PyTPP)(3) and Zn(apPyTPP)(4),suggesting a possibility for an intramolecular electron transfer from the singlet excited state of zinc porphyrin unit to the cobalt centre in the molecular devices.Photochemical H2-evolving studies show that complexes 1 and 2 are efficient molecular photocatalysts for visible light-driven H2 generation from water with triethylamine as a sacrificial electron donor in THF/H2 O,with turnover numbers up to 46 and 35 for 1 and 2,respectively.In contrast to these molecular devices,the multicomponent catalyst of zinc porphyrin and [Co(dmgH) 2 PyCl] did not show any fluorescence quenching and as a consequence,no H2 gas was detected by GC analysis in the presence of triethylamine with irradiation of visible light.The plausible mechanism for the photochemical H2 generation with these molecular devices is discussed. | ZHANG Pan WANG Mei LI XueQiang CUI HongGuang DONG JingFeng SUN LiCheng | 2012 | Science China Chemistry2012，55，7： | 1 |
| 16 | Assessment of self-archiving in institutional repositories: Depositorship and full-text availability 显示文摘 | Xia Jingfeng Sun Li | 2007 | SERIALS REVIEW2007，33，1： | 1 |
| 17 | Factors to assess self-archiving in institutional repositories显示文摘 | Xia Jingfeng Sun Li | 2007 | SERIALS REVIEW2007，33，2： | 1 |
| 18 | Detection and estimation of mixed paddy rice cropping patterns with MODIS data显示文摘 | Dailiang Peng Alfredo R. Huete Jingfeng Huang Fuming Wang Huasheng Sun | 2010 | International Journal of Applied Earth Observations and Geoinformation2010，，1： | 1 |
| 19 | Water-soluble polysaccharide from the fruiting bodies of Chroogomphis rutilus (Schaeff.: Fr.) O. K. Miller: Isolation, structural features and its scavenging effect on hydroxyl radical显示文摘 | Yongxu Sun Xia Li Jingfeng Yang Jicheng Liu John F. Kennedy | 2009 | Carbohydrate Polymers2009，，3： | 1 |
| 20 | Factors to Self-Archiving in Institutional Repositories显示文摘 | Jingfeng Xia Li Sun | 2007 | Serials Review2007，，33： | 1 |
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