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| 1 | History of the infantile hepatic hemangioma:From imaging to generating a differential diagnosis显示文摘We aim to provide an up-to-date summary of infantile hepatic hemangioma(IHH) and its misnomers and to dialectically present the differential diagnosis of these rare entities of the liver.Eligible peer-reviewed articles on hepatic infantile hemangiomas,published between 2000 and 2015,were reviewed for this study.IHH is the most common hepatic vascular tumor in children.Once a liver mass is identified in an infant,the differential diagnosis ranges from vascular malformations to benign and malignant tumors including mesenchymal hamartoma,hepatoblastoma,metastatic neuroblastoma,so careful physical examination,imaging studies,and,if indicated,tumor markers and biopsy,are of pivotal importance to ascertain the correct diagnosis.Despite the benign nature of IHHs,some of these lesions may demand medical and/or surgical intervention,especially for multiple and diffuse IHH.Complications can include hepatomegaly,hypothyroidism and cardiac failure.Therefore,a close follow-up is required until complete involution of the lesions.We propose an algorithm to guide the physicians towards the proper management of hepatic lesions. | Maria Gnarra Gerald Behr Alison Kitajewski June K Wu Sudha A Anupindi Carrie J Shawber Nick Zavras Dimitrios Schizas Chris Salakos Konstantinos P Economopoulos | 2016 | World Journal of Clinical Pediatrics2016,5,3: | 27 |
| 2 | Endocytosis unplugged: multiple ways to enter the cell显示文摘Endocytosis 在房间表面发生并且与它的成分膜蛋白质和类脂化合物一起包含血浆膜(下午) 的成为主观。Endocytosis 涉及细胞外的周围的采样并且也服务调整在房间表面开始的各种各样的过程。这些包括滋养的举起,从房间表面受体,和为在 metazoans 工作的房间和织物的许多另外的过程必需品发信号。它对下午类脂化合物和蛋白质动态平衡的维护也中央。有成为主观的多重工具并发地操作,在房间表面。与在高分辨率的可视化技术的前进,同时追踪多重 endocytic 货物现在是可能的,揭示在一个单个房间的 endocytic 进程的显著差异。实时房间成像和有效基因操作的联合也帮助了在成为主观的这些机制理解分子的播放器的功能的层次。这里,我们提供各种各样的 endocytic 线路的一篇报道,他们越过数的操作和出现的机制。 | Sudha Kumari Swetha MG Satyajit Mayor | 2010 | Cell Research2010,20,3: | 19 |
| 3 | Antioxidant and hepatoprotective effects of Hypsizygus ulmarius polysaccharide on alcoholic liver injury in rats显示文摘Hypsizygus ulmarius polysaccharide(HUP)is a water-soluble polysaccharide obtained by hot water extraction,followed by precipitation and deproteinization.The characteristics of HUP,antioxidant activity and liver protection against alcohol-induced liver damage were studied.Structural characteristics indicate that the HUP is a pyran-type polysaccharide with a molecular weight of 2076 Da.In antioxidant scavenging assay,HUP showed moderate DMPD radical scavenging activity,cupric ion reducing antioxidant capacity and inhibitory effect against lipid peroxidation in a dose-dependent manner.Regarding in vivo hepatoprotective activity,compared with the ethanol induction group,pre-treatment of low and high doses of HUP signifi cantly reduced the behaviours of serum enzymes,lowered the levels of hepatic oxidative stress markers,restored the levels of biochemical constituents,enhanced the levels of liver and serum enzymatic antioxidants and non-enzymatic antioxidants,and improved the serum lipid levels of alcohol-intoxicated rats.The hepatoprotective effect of HUP was comparable to positive control silymarin.Besides,HUP pre-treatment signifi cantly normalized the histopathological changes induced by ethanol.The results indicate that HUP could be used as a functional food and may protect the biological system from oxidative stress through its antioxidant activity,thus having a signifi cant protective effect on acute alcoholic liver injury. | Sudha Govindan Angu Jayabal Jayasakthi Shanmugam Prasanna Ramani | 2021 | Food Science and Human Wellness2021,10,4: | 6 |
| 4 | Green-synthesized gold nanoparticles from Plumeria alba flower extract to augment catalytic degradation of organic dyes and inhibit bacterial growth显示文摘 | Rani Mata Aswathy Bhaskaran Sudha Rani Sadras | 2016 | Particuology2016,14,1: | 4 |
| 5 | 结核病的性别差异:南印度某农村地区DOTS项目报告显示文摘背景:南印度 Tiruvallur 地区。目的:了解 14 岁以上成年人在结核感染和患病、就医途径、就医行为、诊断延误、接受 DOT的方便程度、疾病歧视以及治疗依从性等方面的性别差异。方法:相关数据主要来自:1)社区调查,2)在公立初级保健卫生机构(PHIS)主动就医的病人,3)转诊到 PHIS 进行痰涂片检查的可疑结核病人;4)DOTS 策略下的登记报告结核病人。并将社区调查结果与 PHIS 登记病人进行比较。结果:社区人群中 66%的男性和 57%的女性感染了结核菌;男性和女性的涂阳肺结核患病率分别为568/10 万和87/10 万。在 PHIS 就医的男性少于女性,男女之比为 68:100。女性占社区调查发现涂阳病人的 13%;占 PHIS 发现病人的 20%(P<0.05)。随着年龄的增长,男性和女性的登记率显著降低。女性感觉难于与家人讨论自己病情的比例要高于男性(21%∶14%),也更需要有人陪伴去接受 DOT(11%∶6%)。男性的治疗中断率比女性高 1 倍(19%∶8%;P<0.01)。结论:尽管女性发病后更容易遭受歧视和不便,但女性更易于利用医疗服务、接受 DOTS 策略登记以及依从治疗。而男性以及高龄病人在诊断和 DOT服务方面更需要帮助。 | R. Balasubramanian R. Garg T. Santha P. G. Gopi R. Subramani V. Chandrasekaran A. Thomas R. Rajeswari S. Anandakrishnan M. Perumal C. Niruparani G. Sudha K. Jaggarajamma T. R. Frieden P. R. Narayanan 刘小秋 | 2004 | 结核与肺部疾病杂志2004,7,4: | 4 |
| 6 | Evaluation of Traditional Indian Antidiabetic Medicinal Plants for Human Pancreatic Amylase Inhibitory Effect In Vitro显示文摘 | Sudha Ponnusamy Remya Ravindran Smita Zinjarde Shobha Bhargava Ameeta Ravi Kumar | 2010 | Evidence-Based Complementary and Alternative Medicine2010,,: | 3 |
| 7 | 过渡金属氢化物TMH(TM=Mo、TC、RU)的显微组织、电子特性和力学性能的第一性原理研究(英文)显示文摘通过基于广义梯度近似密度泛函理论的第一性原理研究过渡金属氢化物TMH(TM=Mo、TC、RU)的显微组织、电子特性和力学性能。在被研究的5个晶体结构中,立方结构比六方晶结构更稳定。预测了不同过渡金属氢化物在高压下的相结构转变,如:MoH中从ZB结构到WC结构的转变、在TcH中从NaCl结构到NiAs结构的转变以及在RuH中从NaCl结构到ZB结构再到NiAs结构的转变。弹性常数的计算表明:三种氢化物的力学性能在环境压力下是稳定的。 | G. SUDHA PRIYANGA A.T.ASVINI MEENAATCI R. RAJESWARA PALANICHAMY K.IYAKUTTI | 2013 | Transactions of Nonferrous Metals Society of China2013,23,9: | 3 |
| 8 | SDN assisted Stackelberg Game model for LTE-WiFi offloading in 5G networks显示文摘The data traffic that is accumulated at the Macro Base Station(MBS)keeps on increasing as almost all the people start using mobile phones.The MBS cannot accommodate all user’s demands,and attempts to offload some users to the nearby small cells so that the user could get the expected service.For the MBS to offload data traffic to an Access Point(AP),it should offer an optimal economic incentive in a way its utility is maximized.Similarly,the APs should choose an optimal traffic to admit load for the price that it gets from MBS.To balance this tradeoff between the economic incentive and the admittance load to achieve optimal offloading,Software Defined Networking(SDN)assisted Stackelberg Game(SaSG)model is proposed.In this model,the MBS selects the users carefully to aggregate the service with AP,so that the user experiencing least service gets aggregated first.The MBS uses the Received Signal Strength Indicator(RSSI)value of the users as the main parameter for aggregating a particular user for a contract period with LTE and WiFi.Each player involved in the game tries to maximize their payoff utilities,and thus,while incorporating those utilities in real-time scenario,we obtain maximum throughput per user which experiences best data service without any lack in Quality of Experience(QoE).Thus,the proposed SaSG model proves better when compared with other game theory models,and hence an optimal data offloading is achieved. | Sudha Anbalagan Dhananjay Kumar Gunasekaran Raja Alkondan Balaji | 2019 | Digital Communications and Networks2019,5,4: | 3 |
| 9 | Molt and reproduction enhancement together with hemolymph ecdysteroid elevation under eyestalk ablation in the female fiddler crab,Uca triangularis(Brachyura:Decapoda)显示文摘We present the results of eyestalk extirpation experiments performed on the fiddler crab, Uca triangularis at seasons of molting and reproduction, with a view to have a better understanding of the regulatory mechanisms of these two highly energy-demanding processes. Bilateral eyestalk ablation resulted in precocious acceleration of both molting and reproduction, irrespective of the season at which each experiment was conducted. The rate of accelerated ovarian growth, however, was maximum if the eyestalk ablation was conducted during August–January, the breeding season in the wild, or in February–May(molting-reproductive season), wherein a section of the wild population would be engaged in molting and another section in breeding. The highest degree of precocious molt acceleration, on the other hand, was obtained during June–July when the population was primarily engaged in molting, but with no reproductive activity. The precocious oocyte maturation(due to de-eyestalking) was minimal in June–July. Significantly, the eyestalk ablation also resulted in a dramatic increase in the hemolymph ecdysteroid titer, revealing that a high ecdysteroid titer would have no restraining influence on vitellogenesis. No spawning was, however, observed among de-eyestalked females, even though their final oocyte size surpassed the size of the normal mature oocytes, implying that spawning is not exclusively under the control of eyestalk hormones. A comparative study performed on the vitelline components of the experimentals and the controls revealed that the precociously incorporated yolk under eyestalk ablation was biochemically impoverished. These results indicate that throughout the annual cycle, both the somatic and the reproductive growth of U. triangularis are under the influence of inhibitory principles from the eyestalks. It is also revealing that mere deprival of the inhibitory principles does not culminate into successful vitellogenesis. Arguably, the inhibitory influence from the eyestalks could be a prerequisite for normal healthy maturation of the oocytes and spawning. | SUPRIYA Nagathinkal T SUDHA Kappalli KRISHNAKUMAR Velayudhannair ANILKUMAR Gopinathan | 2017 | Chinese Journal of Oceanology and Limnology2017,35,3: | 3 |
| 10 | Atrial fibrillation ablation in patients with gastroesophageal reflux disease or irritable bowel syndrome—the heart to gut connection!显示文摘 | Yeruva Madhu Reddy Dhssraj Singh Darbhamulla Nagarajan Jayasree Pillarisetti Mazda Biria Hemant Boolani Martin Emert Vineela Chikkam Kay Ryschon James Vacek Sudha Bommana Donita Atkins Atul Verma Mojtaba Olyaee Buddhadeb Dawn Dhanunjaya Lakkireddy | 2013 | Journal of Interventional Cardiac Electrophysiology2013,,3: | 2 |
| 11 | Characterization of cytotoxic compound from marine sediment derived actinomycete Streptomyces avidinii strain SU4显示文摘Objective:To investigate the cytotoxic activity of actinomycete isolated from marine sediment.Methods:In the present study the DNA was isolated and the ITS region of 16s rRNA was amplified by polymerase chain reaction,using two universal bacterial primers,1492K(5'-GGTTACCTTG'TTAC GACTT-3')and Eubac27F(5'-AGAGTTTGATCCTGGCTC AG-3').The amplified products were purified using TIANgel mini purification kit,ligated to MD18-T simple vector(TaKaRa),and transformed into competent cells of Escherichia coli DH5α.16S rRNA gene fragment was sequenced using forward primer M13F(-47)and reverse primer M13R(-48).Blast search sequence similarity was found against the existing non-redundanl nucleotide sequence database thus,identified as Streptomyces sp SU,Streptomyces rubralavandulae strain SU1,Streptomyces cacaoi strain SU2,Streptomyces cavourensis strain SU3,Streptomyces avidinii strain SU4,Streptomyces globisporus strain SU5,Streptomyces variabilis strain SU6,Streptomyces coelicolor strain SU 7.Among the eight identified isolates,one actinomycete Streptomyces avidinii strain SU4 was selected for further study.Results:Crude extract of the actinomycete isolate exhibited IC_(50)in 64.5μg against Hep-2 cell line,250μg in VERO cell line.This value is very close to the criteria of cytotoxicity activity for the crude extracts,as established by the American National Cancer Institute(NCI)is in IC_(50)<30μg/mL.The CC MS analysis showed that the active principle might be 1,2-benzenedicarboxylic acid,bis(2-methylpropyl)ester(12.17%),isooctyl phthalate(15.29%)with the retention time 15.642 and 21.612,respectively.Conclusions:This study clearly proves that the marine sediment derived actinomycetes with bioactive metabolites can be expected to provide high quality biological material for high throughout biochemical and anticancer screening programs.These results help us to conclude that the potential of using metabolic engineering and post genomic approaches to isolate more bioactive compounds and make their possible commercial application is not far off. | Sudha S Masilamani Selvam M | 2012 | Asian Pacific Journal of Tropical Biomedicine2012,2,10: | 2 |
| 12 | Intensification of Statin Therapy Results in a Rapid Reduction in Atherosclerotic Inflammation: Results of A Multi-Center FDG-PET/CT Feasibility Study显示文摘 | Ahmed Tawakol Zahi A. Fayad Robin Mogg Achilles Alon Michael T. Klimas Hayes Dansky Sharath S. Subramanian Amr Abdelbaky James H.F. Rudd Michael E. Farkouh Irene O. Nunes Chan R. Beals Sudha S. Shankar | 2013 | Journal of the American College of Cardiology2013,,: | 2 |
| 13 | Efficacy and safety of standard and anti-reflux self-expanding metal stent: A systematic review and meta-analysis of randomized controlled trials显示文摘BACKGROUND Self-expanding metal stents are the main palliative treatment modality for unresectable esophageal cancer. Gastroesophageal reflux is a common adverse outcome after placement of esophageal stent for cancer involving the gastroesophageal junction and the gastric cardia. Anti-reflux stents with valve have been designed to prevent the acid reflux. The superiority of anti-reflux stent over standard stent in preventing gastroesophageal reflux has not been established well. This study compares the anti-reflux stent and the standard stent in terms of their efficacy to prevent acid reflux.AIM To compare the standard and the anti-reflux stents in terms of their efficacy,safety, and complications.METHODS The meta-analysis included 8 randomized clinical trials(RCTs) to compare pooled outcomes of total 395 patients. Primary outcomes include improvement in reflux symptoms and dysphagia score. Secondary outcomes include complications of stent migration, occlusion, and bleeding.RESULTS A total of eight RCTs were included in the meta-analysis. Compared to the standard stent, the anti-reflux stent showed a trend towards reduction in the dysphagia score without reaching a statistical significance [Standardized mean difference(SMD):-0.33(-0.71, 0.05); P = 0.09, I2: 37%]. There was no statistical difference in the gastrointestinal reflux(GER) scores between the two types of stents [SMD:-0.17(-0.78, 0.45); P = 0.008, I2: 74%]. Compared to standard stent,anti-reflux stent showed no difference in the risk of stent migration [OR: 1.37(0.66, 2.83); P = 0.40, I2: 0 %], bleeding [OR: 1.43(0.40, 5.13); P = 0.59, I2: 0 %], and obstruction [OR: 1.66(0.60, 4.60); P = 0.33, I2: 0 %].CONCLUSION Traditional self-expanding standard esophageal stent and anti-reflux stent with valve are similar in terms of outcomes and complications. | Sudha Pandit Hrishikesh Samant James Morris Steven J Alexander | 2019 | World Journal of Gastrointestinal Endoscopy2019,11,4: | 2 |
| 14 | Idiopathic hypothalamic diabetes insipidus, pituitary stalk thickening, and the occult intracranial genninoma in children and adolescents 显示文摘 | Sudha L Mootha L Anthony J | 1997 | J Clini Endocrinol Metabol1997,82,: | 1 |
| 15 | Evaluation of genotoxicity in petrolstation workers in south India using micronucleus assay 显示文摘 | Sudha S Bindhya S Athena F | 2010 | IndustrailHealth2010,48,: | 1 |
| 16 | Influencc of injection rate of hyperbaric bupivacaine on spinal block in parturients:a randomized trial显示文摘 | Sudha S Morley-Forster PK Shamsah M | | 0,,04: | 1 |
| 17 | Piriformospora indica ,a cultivable plant-growth promoting root endoplryte显示文摘 | Varma A Verma S Sudha A | 1999 | Applied and Environmental Microbiology1999,65,6: | 1 |
| 18 | Reactive astrocytes promote the metastatic growth of breast cancer stem‐like cells by activating Notch signalling in brain显示文摘 | Fei Xing Aya Kobayashi Hiroshi Okuda Misako Watabe Sudha K. Pai Puspa R. Pandey Shigeru Hirota Andrew Wilber Yin‐Yuan Mo Brian E. Moore Wen Liu Koji Fukuda Megumi Iiizumi Sambad Sharma Yin Liu Kerui Wu Elizabeth Peralta Kounosuke Watabe | 2013 | EMBO Mol Med2013,,3: | 1 |
| 19 | Structural and electronic properties of small beryllium clusters: A theoretical study显示文摘 | Sudha Srinivas Julius Jellinek | 2004 | J Chem Phys2004,121,: | 1 |
| 20 | Amylolytic bacteria producing lactic acid显示文摘 | VISHNU C SUDHA R K GOPAL R | 1998 | J Sci Ind Res1998,57,: | 1 |