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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | 踝关节创伤后关节炎的相关危险因素:一项随访18年的回顾性研究显示文摘踝关节创伤后关节炎十分常见,其发生率比髋膝关节高得多,而目前对其危险因素评估的长期随访研究报道很少。作者对1988年1月-1997年12月的373例进行切开复位内固定的踝关节骨折进行了回顾性研究,并进行统计学分析。Pilon骨折、距骨骨折及年龄〈18岁者未纳入研究。 | Lübbeke A Salvo D Stern R Hoffmeyer P Holzer N Assal M. 于涛 俞光荣 | 2012 | 中国矫形外科杂志2012，20，18： | 14 |
| 3 | Impact of human cytomegalovirus latent infection on myeloid progenitor cell gene expression显示文摘 | Slobedman B Stern J L Cunningham A L Abendroth A Abate D A Mocarski E S | 2004 | J Virol2004，78，8： | 1 |
| 4 | Studies on flaovr volatiles of some sweet corn products显示文摘 | Buttery R G Stern D J Ling L C | 1982 | Journal of Agricultural and Food Chemistry1982，30，： | 1 |
| 5 | XPD codon 751 polymorphism,metabolism genes,smoking,and bladder cancer risk显示文摘 | STERN M C JOHNSON L R BELL D A | 2002 | Cancer Epidemiol Biomarkers Prev2002，11，101： | 1 |
| 6 | Volatile constituents in guava显示文摘 | Stevens K L Brekke J E Stern D J | 1970 | Journal of Agriculture and Food Chemistry1970，18，： | 1 |
| 7 | Catalytic dehydrogenation (DH) of light paraffins combined with selective hydrogen combustion (SHC) : I DH-SHC-DH catalysts in series (co-fed process mode) 显示文摘 | GRASSELLI R K STERN D L TSIKOYIANNIS J G | 1999 | Appl Catal A1999，189，1： | 1 |
| 8 | A Domain and TypeEnforcement UNIX Prototype显示文摘 | Badger L Sterne D F Sherman D L | 1996 | USENIX Computing Systems1996，9，1： | 1 |
| 9 | Effects of protein source on nitrogen metabolism in continuous culture and intestinal digestion in vitro显示文摘 | Calsamiglia S Stern M D Firkins J L | 2005 | J Anita Sci2005，73，： | 1 |
| 10 | Catalytic dehydrogenation (DH) of light paraffins combined with selective hydrogen combustion (SHC) : II DH+SHC catalysts physically mixed (redox process mode) 显示文摘 | GRASSELLI R K STERN D L TSIKOYIANNIS J G | 1999 | Appl Catal A1999，189，1： | 1 |
| 11 | Direct measurement of SR release flux by tracking' Ca2+ spikes~in rat cardiac myo- cytes显示文摘 | Song L S Sham J S Stern M D | 1998 | J Physiol1998，512，3： | 1 |
| 12 | Hierarchical clustering of ryanodine receptors enables emergence of a calcium clock in sinoatrial node ceils 显示文摘 | STERN M D MALTSEVA L A JUHASZOVA M | 2014 | J Gen Physiol2014，143，5： | 1 |
| 13 | Interaction of chromatin-associated Plkl and Mcm7 显示文摘 | Tsvetkov L Stern D F | 2005 | J Biol Chem2005，280，11： | 1 |
| 14 | The Chlamydomonas reinhardtii plastid chromosome:islands of genes in a sea of repeats显示文摘 | MAUL J E LILLY J W CUI L DE PAMPHILIS C W MILLER W HARRIS E H STERN D B | 2002 | Plant Cell2002，14，11： | 1 |
| 15 | The effect of rumen ammonia concentrate on dry matter disap- pearance in situ显示文摘 | Ortega M E Stern M D Satter L D | 1979 | Dairy Sci1979，，： | 1 |
| 16 | A molecular pathway determining left-right asymmetry in chick embryogenesis显示文摘 | JOHNSON R L STERN C D | 1995 | Cell1995，82，： | 1 |
| 17 | A 3' stem/loop structure of the Chlamydomonas chloroplast atpB gene regulates mRNA accumulationln vivo 显示文摘 | Stern D B Raswanski E R Kindle K L | 1991 | Plant Cell1991，3，3： | 1 |
| 18 | A value-belief-norm theory of support for social movements:The case of environmentalism显示文摘 | Stern P C Dietz T Abel T D Guagnano G A Kalof L (1999) | 1999 | Human Ecology Review1999，6，2： | 1 |
| 19 | Regenerable solid sorbents for claus tailgas cleanup: a treatment process for the catalytic removal of SOx and H2S 显示文摘 | BUCHANAN J S STERN D L NARIMAN K E | 1996 | Ind Eng Chem Res1996，35，8： | 1 |
| 20 | Campylobacter jejuni -an emerging foodborne pathogen显示文摘 | Altekused S F Stern N J Fields P I Swerdlow D L | 1999 | Emerg Infect Dis1999，5，： | 1 |
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