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| 1 | 2型糖尿病患者个体化血糖控制目标和药物治疗显示文摘'有效管理糖尿病全球合作组织'(下称'糖尿病全球合作组织')成立的宗旨是为临床提供实用指南以改善糖尿病患者的预后,制定并修改相关策略以改善T2DM患者血糖控制情况。糖尿病全球合作组织提倡对糖尿病患者实行个体化治疗方案,明确需要特殊考虑T2DM患者亚组人群。这篇文章基于此前发表的文献,扩大了实用指南的范围,包括有并发症的新诊断T2DM患者和妊娠期糖尿病(GDM)患者。良好血糖控制是T2DM管理的基石,在预防或延缓糖尿病并发症的发生、发展过程中发挥重要作用。个体化治疗目标和安全及时的血糖达标治疗方案至关重要。另外,还需制定更全面的护理计划以降低心血管风险和改善患者预后。 | 张晓梅 纪立农 Bailey CJ Aschner P Stefano Del Prato LaSalle J JI Li-nong Matthaei S | 2014 | 中国糖尿病杂志2014,22,10: | 16 |
| 2 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019,62,2: | 11 |
| 3 | Evaluation of biodegradable electric conductive tube-guides and mesenchymal stem cells显示文摘AIM: To study the therapeutic effect of three tubeguides with electrical conductivity associated to mesenchymal stem cells(MSCs) on neuro-muscular regeneration after neurotmesis.METHODS: Rats with 10-mm gap nerve injury were tested using polyvinyl alcohol(PVA), PVA-carbon nanotubes(CNTs) and MSCs, and PVA-polypyrrole(PPy). The regenerated nerves and tibialis anterior muscles were processed for stereological studies after 20 wk. The functional recovery was assessed serially for gait biomechanical analysis, by extensor postural thrust, sciatic functional index and static sciatic functionalindex(SSI), and by withdrawal reflex latency(WRL). In vitro studies included cytocompatibility, flow cytometry, reverse transcriptase polymerase chain reaction and karyotype analysis of the MSCs. Histopathology of lung, liver, kidneys, and regional lymph nodes ensured the biomaterials biocompatibility. RESULTS: SSI remained negative throughout and independently from treatment. Differences between treted groups in the severity of changes in WRL existed, showing a faster regeneration for PVA-CNTs-MSCs(P < 0.05). At toe-off, less acute ankle joint angles were seen for PVA-CNTs-MSCs group(P = 0.051) suggesting improved ankle muscles function during the push off phase of the gait cycle. In PVA-PPy and PVA-CNTs groups, there was a 25% and 42% increase of average fiber area and a 13% and 21% increase of the 'minimal Feret's diameter' respectively. Stereological analysis disclosed a significantly(P < 0.05) increased myelin thickness(M), ratio myelin thickness/axon diameter(M/d) and ratio axon diameter/fiber diameter(d/D; g-ratio) in PVA-CNT-MSCs group(P < 0.05). CONCLUSION: Results revealed that treatment with MSCs and PVA-CNTs tube-guides induced better nerve fiber regeneration. Functional and kinematics analysis revealed positive synergistic effects brought by MSCs and PVA-CNTs. The PVA-CNTs and PVA-PPy are promising scaffolds with electric conductive properties, bio- and cytocompatible that might prevent the secondary neurogenic muscular atrophy by improving the reestablishment of the neuro-muscular junction. | Jorge Ribeiro Tiago Pereira Ana Rita Caseiro Paulo Armada-da-Silva Isabel Pires Justina Prada Irina Amorim Sandra Amado Miguel Franca Carolina Goncalves Maria Ascensao Lopes Jose Domingos Santos Dina Morais Silva Stefano Geuna Ana Lúcia Luís Ana Colette Maurício | 2015 | World Journal of Stem Cells2015,7,6: | 2 |
| 4 | Lipid-Rich Variant of Pancreatic Endocrine Neoplasms显示文摘 | Rajendra Singh Olca Basturk David S Klimstra Giuseppe Zamboni Runjan Chetty Sanaa Hussain Stefano La Rosa Asli Yilmaz Paola Capelli Carlo Capella Jeanette D Cheng N Volkan Adsay | 2006 | The American Journal of Surgical Pathology2006,,2: | 2 |
| 5 | A variational ap- proach to problems in calibration of multiple cameras finder from natural scenes 显示文摘 | GOZDE U ANTHONY Y STEFANO S | 2007 | IEEE Transactions on Pattern Anal- ysis and Machine Intelligence2007,29,8: | 1 |
| 6 | Chemokine re- ceptor CCR5 expression in conjunctival epithelium of pa- tients with dry eye syndrome 显示文摘 | ABHA G MARTA S STEFANO B REZA D | 2006 | Arch Ophthalmol2006,124,5: | 1 |
| 7 | Mapping automotive process control on IEC/ISA FieldBus functionalities 显示文摘 | Cavalieri S Stefano A D Mirabella O | 1996 | Computers in Industry1996,28,3: | 1 |
| 8 | Dental disease and risk of coronary heart disease and mortality 显示文摘 | de Stefano F Anda R F Kahn H S | 1993 | Br Med J1993,306,6879: | 1 |
| 9 | ZNCC-based template matching using bounded partial correlation 显示文摘 | STEFANO L D MATTOCC I S TOMBAR I F | 2005 | Pat- tern Recognition Letters2005,,14: | 1 |
| 10 | Food analysis and food authentication by peptide nucleic acidPNA)-based technologies显示文摘 | Stefano S Roberto C Tullia T | | 0,,01: | 1 |
| 11 | Asymptotic sideslip angle and yaw rate decoupling control in four - wheel steering Vehicles 显示文摘 | RICCARDO M STEFANO S | 2008 | Vehicle System Dynamics2008,,9: | 1 |
| 12 | Knowledge assets and firm international performance 显示文摘 | STEFANO D ANTONELLA Z ROGER S | 2014 | International Business Review2014,23,7: | 1 |
| 13 | Low Frequency Electromagnetic Sensor for Indirect Measurement of Glucose Concentration: In Vitro Experiments in Different Conductive Solutions显示文摘 | Andrea T Stefano S Domenic C | 2010 | SENSORS2010,106,: | 1 |
| 14 | 3-o-methylfunicone, a fungitoxic metabolite produced by the fungus Penicillium pinophilum显示文摘 | Stefano S D Nicoletti R Milone A | 1999 | Phytochemistry1999,52,8: | 1 |
| 15 | Choline is increased in pre-lesional normal appearing white matter in multiple sclerosis显示文摘 | Tartaglia MC Narayanan S De Stefano N | 2002 | J Neurol2002,249,10: | 1 |
| 16 | Effect of all-trans retinoic acid on procoagulant and fibrinolytic activities of cultured blast cells from patients with acute promyelocytic leukemia显示文摘 | DE STEFANO V TEOFILI L SICA S | | 0,,: | 1 |
| 17 | A Fast Area-based Stereo Matching Algorithm显示文摘 | Stefano L D Marchionni M Mattoccia S | 2004 | Image and Vision Computing2004,22,12: | 1 |
| 18 | A fast area_based stereo matching algorithm 显示文摘 | Stefano L D Marehionni M Mattoccia S | 2004 | Image and Vision Computing2004,22,12: | 1 |
| 19 | Diffuse axonal and tissue injury in patients with multiple sclerosis with low cerebral lesion load and no diasbility 显示文摘 | De Stefano N Narayanan S Francis SJ | 2002 | Arch Neurol2002,59,10: | 1 |
| 20 | p130Cas: a versatile scaffold in signaling networks显示文摘 | Defdippi P Di Stefano P Gabodi S | 2006 | Trends Cell Biol2006,16,5: | 1 |