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| 1 | MiR-139-5p inhibits migration and invasion of colorectal cancer by downregulating AMFR and NOTCH1显示文摘MicroRNAs (miRNAs ) 由抑制最近在 carcinogenesis 和转移在我们 non-protein-coding RNA 的角色的理解带给卓见的 posttranscriptional 施加功能。在这研究,我们在 CRC 在 colorectal 癌症(CRC ) 和它的潜在的临床的应用程序描述了函数和 miR-139-5p 的分子的机制。我们发现 miR-139-5p 是显著地, CRC 与邻近的 noncancerous 纸巾(NCT ) 相比取样的在 73.8% 的 downregulated,和减少的 miR-139-5p 与穷人被联系预后。功能的分析证明 miR-139-5p 的那个宫外的表达式在 vivo 在 vitro 和转移压制了 CRC 房间移植和侵略。机械学的调查表明 miR-139-5p 由指向 AMFR 和 NOTCH1 压制 CRC 房间侵略和转移。二基因 phenocopied 击倒 CRC 上的 miR-139-5p 的禁止的效果转移。而且,二基因的蛋白质层次与 NCT 相比是在 CRC 样品的 upregulated,并且相反地与 miR-139-5p 表示相关。增加的 NOTCH1 蛋白质表示与 CRC 病人的差的预后被相关。一起,我们的数据显示 miR-139-5p 为 CRC 是潜在的肿瘤 suppressor 和预示的因素,并且指向 miR-139-5p 可以镇压 CRC 的转移并且改善幸存。 | Mingxu Song Yuan Yin Jiwei Zhang Binbin Zhang Zehua Bian Chao Quan Leyuan Zhou Yaling Hu Qifeng Wang Shujuan Ni Bojian Fei Weili Wang Xiang Du Dong Hua Zhaohui Huang | 2014 | Protein & Cell2014，5，11： | 14 |
| 2 | Control of switched systems with actuator saturation显示文摘This paper is concerned with controller synthesis for linear switched systems with actuator saturation. Based on common Lyapunov function technique and multiple-Lyapunov function technique, two methods for designing state feedback controller are proposed respectively in terms of linear matrix inequalities for the switched systems with saturation. An approach on enlarging the attractive domain is then investigated. The application of the presented approach is illustrated finally by a numerical example. | Yang SONG Zhengrong XIANG Qingwei CHEN Weili HU | 2006 | 控制理论与应用(英文版)2006，4，1： | 5 |
| 3 | Logging Evaluation of the Ordovician Carbonate Reservoir Beds in the Lungudong Region,Tarim Basin显示文摘在最近的年里,大进步在 Tarim 盆的 Lungudong 区域在油和煤气的探索常常被取得了。然而,进步在它的主要生产油的地平线的评估是慢的奥陶纪碳酸盐水库床。基于以前的研究并且在象钻,地质学和油测试那样的各种各样的数据上,在有各单个井的成像和常规记载数据的解释的联合,并且通过分析和比较,在成像并且在这个区域的为碳酸盐水库床的四种类型的常规记载的鉴定方法在这篇论文被总结。为四个水库床参数的计算公式,我。e。在这个区域的页岩内容,孔,渗透和油浸透被建议;并且在这个区域的水库床被划分成三个层次(我, II 和 III ) 由联合油测试数据并且记载数据,水库床的有效的孔的更低的限制和有效水库的破裂孔,床分别地作为 1.8% 和 0.04% 被决定。物理性质参数被常规记载的曲线计算,并且为水库开发的最有益的区域包括地被预言。在飞机上,水库床参数的高值的地区主要在 N-S-trending 罢工滑倒差错被集中, Sangtamu 差错 horst 地区并且接近 LG38 很好区域;垂直地, Yijianfang 形成的水库床参数比 Yingshan 和 Lianglitage 形成的那些好。 | YANG Wenjing XIAO Chengwen LIU Luofu QI Guangzhong JIANG Zhenxue YUAN Yunchun WANG Weili YANG song | 2010 | Acta Geologica Sinica(English Edition)2010，84，5： | 5 |
| 4 | Direct observation of metastable face-centered cubic Sb2Te3 crystal显示文摘尽管阶段变化记忆技术在过去的二十年急速地发展了,关键切换材料的认知仍然忽视一个重要成员,以脸为中心的立方的 Sb 2 Te 3 。除了著名平衡六角形的 Sb 2 Te 3 水晶,我们证明亚稳的以脸为中心的立方的 Sb 是 2 Te 3 阶段确实存在。如此的亚稳的晶体包含随机占据 cationic 格子地点的空缺的大集中。以脸为中心对 Sb 2 Te 3, 由空缺聚集伴随了,与 Ge 2 Sb 2 Te 5 合金。我们证明像共有原子价的契约在亚稳的 Sb 2 Te 3 水晶,从理想的反响的特征背离。如果一种合适的做技术被采用,亚稳的 Sb 2 Te 3 阶段能为认识到 reversibly 快速、低精力的阶段变化存储器应用程序是有希望的。我们的学习可以在新奇阶段变化材料的设计提供新卓见进商品化的 Ge-Sb-Te 系统和帮助增加阶段变化存储器设备的表演。 | Yonghui Zheng Mengjiao Xia Yan Cheng Feng Rao Keyuan Ding Weili Liu Yu Jia Zhitang Song Songlin Feng | 2016 | Nano Research2016，9，11： | 5 |
| 5 | Chinese expert consensus on the management of chimeric antigen receptor T cell therapy-associated coagulopathy显示文摘Chimeric antigen receptor T-cell(CAR-T)therapy has greatly improved the disease remission rate and long-term survival rate of patients with relapsed/refractory hematological malignancies.[1-3]Currently,several commercial CAR-T products are available in the market and numerous CAR-T clinical trials have been conducted.Attention should be paid to the safety of CAR-T therapy.The main adverse effects of CAR-T therapy are cytokine release syndrome(CRS)and immune effector cell-associated neurotoxicity syndrome(ICANS).[4] | Heng Mei Fangping Chen Yue Han Ming Hou He Huang Xiaojun Huang Yuhua Li Aibin Liang Qifa Liu Ting Niu Jun Peng Wenbin Qian Yongping Song Jianxiang Wang Ying Wang Depei Wu Kailin Xu Linhua Yang Renchi Yang Lei Zhang Liansheng Zhang Xi Zhang Xiaohui Zhang Weili Zhao Weidong Han Yu Hu | 2022 | Chinese Medical Journal2022，，14： | 4 |
| 6 | Optical rogue wave in random fiber laser显示文摘The famous demonstration of optical rogue waves(RWs),a powerful tool to reveal the fundamental physics in different laser scenarios,opened a flourishing time for temporal statistics.Random fiber laser(RFL)has likewise attracted wide attention due to its great potential in multidisciplinary demonstrations and promising applications.However,owing to the distinctive cavity-free structure,it is a scientific challenge to achieve temporal localized RWs in RFLs,whose feedback arises from multiple scattering in disordered medium.Here,we report the exploration of RW in the highly skewed,transient intensity of an incoherently pumped RFL for the first time,to our knowledge,and unfold the involved kinetics successfully.The corresponding frequency domain measurements demonstrate that the RW event arises from a crucial sustained stimulated Brillouin scattering process with intrinsic stochastic nature.This investigation highlights a novel path to fully understanding the complex physics,such as photon propagation and localization,in disordered media. | JIANGMING XU JIAN WU JUN YE JIAXIN SONG BAICHENG YAO HANWEI ZHANG JINYONG LENG WEILI ZHANG PU ZHOU YUNJIANG RAO | 2020 | Photonics Research2020，8，1： | 4 |
| 7 | Mechanisms of Traditional Chinese Medicine Bushenantai granules(补肾安胎颗粒) in promoting angiogenesis at the maternal-fetal interface of recurrent spontaneous abortion mice显示文摘OBJECTIVE:To assess the effects of Bushenantai(BSAT)granule(补肾安胎颗粒)on angiogenesis-related factors[E2,P,and vascular endothelial growth factor(VEGF)]at the maternal-fetal interface of recurrent spontaneous abortion(RSA)mice,and to evaluate the role of BSAT in promoting angiogenesis at the maternal-fetal interface by influencing the expression of sex hormones,and VEGF.METHODS:A mouse model with normal pregnancy and another with Clark’s classic RSA were established.The RSA mice were randomly assigned to six groups:normal,model,progesterone,high-doseBSAT granule(BSAT-H),medium-dose-BSAT granule(BSAT-M),and low-dose-BSAT granule(BSAT-L)(n=10 for each group).The embryo loss rate and the histopathological changes in the decidual tissues were measured.Serum levels of estrogen(E2),progesterone(P),and VEGF were detected by enzyme-linked immunosorbent assay.The m RNA and protein expressions of estradiol receptor(ER),progesterone receptor(PR),VEGF,and vascular endothelial growth factor receptor 2(VEGFR2)in the decidual tissues were identified by immunohistochemistry,Western blotting,and quantitative reverse transcription polymerase chain reaction.RESULTS:The embryo loss rate in all groups that received BSAT treatment was reduced,while the number of blood vessels at decidual tissues was increased.The serum levels of E2,P and VEGF were elevated,and the m RNA and protein expressions of ER,PR,VEGF,and VEGFR2 in the decidual tissues were enhanced.CONCLUSION:BSAT can improve angiogenesis at the maternal-fetal interface and reduce the embryo loss rate,which may be associated with its ability to increase the serum levels of estrogen,progesterone,and VEGF,in addition to up-regulation of m RNA and protein expression of ER,PR,VEGF,and VEGFR2 in the decidual tissues. | LI Yuanqi LI Weili YU Xinhui WU Hua WANG Yuanzhong JIN Ya HAO Lele LIU Mingmin SONG Xiaoge | 2021 | Journal of Traditional Chinese Medicine2021，41，4： | 3 |
| 8 | 2022 Chinese expert consensus and guidelines on clinical management of toxicity in anti-CD19 chimeric antigen receptor T-cell therapy for B-cell non-Hodgkin lymphoma显示文摘Adoptive cellular immunotherapy with chimeric antigen receptor(CAR)T cells has emerged as a novel modality for treating relapsed and/or refractory B-cell non-Hodgkin lymphoma(B-NHL).With increasing approval of CAR T-cell products and advances in CAR T cell therapy,CAR T cells are expected to be used in a growing number of cases.However,CAR T-cell-associated toxicities can be severe or even fatal,thus compromising the survival benefit from this therapy.Standardizing and studying the clinical management of these toxicities are imperative.In contrast to other hematological malignancies,such as acute lymphoblastic leukemia and multiple myeloma,anti-CD19 CAR T-cell-associated toxicities in B-NHL have several distinctive features,most notably local cytokine-release syndrome(CRS).However,previously published guidelines have provided few specific recommendations for the grading and management of toxicities associated with CAR T-cell treatment for B-NHL.Consequently,we developed this consensus for the prevention,recognition,and management of these toxicities,on the basis of published literature regarding the management of anti-CD19 CAR T-cell-associated toxicities and the clinical experience of multiple Chinese institutions.This consensus refines a grading system and classification of CRS in B-NHL and corresponding measures for CRS management,and delineates comprehensive principles and exploratory recommendations for managing anti-CD19 CAR T-cell-associated toxicities in addition to CRS. | Ping Li Yang Liu Yun Liang Jian Bo Sujun Gao Yongxian Hu Yu Hu He Huang Xiaojun Huang Hongmei Jing Xiaoyan Ke Jianyong Li Yuhua Li Qifa Liu Peihua Lu Heng Mei Ting Niu Yongping Song Yuqin Song Liping Su Sanfang Tu Jianxiang Wang Depei Wu Zhao Wang Kailin Xu Zhitao Ying Qingming Yang Yajing Zhang Fengxia Shi Bin Zhang Huilai Zhang Xi Zhang Mingfeng Zhao Weili Zhao Xiangyu Zhao Liang Huang Jun Zhu Wenbin Qian Weidong Han Aibin Liang | 2023 | Cancer Biology & Medicine2023，20，2： | 3 |
| 9 | Highly efficient achromatic subdiffraction focusing lens in the near field with large numerical aperture显示文摘The achromatic subdiffraction lens with large numerical aperture(NA)is of significant importance in optical imaging,photolithography,spectroscopy,and nanophotonics.However,most of the previous research on sub-diffraction lenses has been restricted by limited bandwidth and efficiency as well as severe chromatic aberrations.In this paper,a semicircular gradient index lens(sGRIN)with a modified refractive index profile originated from a Maxwell fish-eye lens is put forward to achieve highly efficient(above 81%)achromatic(4–20 GHz)subdiffraction focusing at the focusing line(around 0.28λ)with large NA of 1.3 and broadband diffraction-limited far-field radiation(4–16 GHz)theoretically,which overcomes the drawbacks of previous works.The presented lens is designed by gradient dielectric metamaterials.Evanescent waves ignited at the lens/air interface and transformation of electromagnetic(EM)waves with high spatial frequency in sGRIN to EM waves with low spatial frequency in air are responsible for subdiffraction focusing and diffraction-limited far-field radiation,respectively.Experimental results demonstrate the excellent performance of achromatic subdiffraction focusing and diffraction-limited far-field radiation.The presented lens has great potential to be applied in subdiffraction imaging systems. | JIN CHEN HONGCHEN CHU YUN LAI HUANYANG CHEN WEILI SONG MINGJI CHEN DAINING FANG | 2021 | Photonics Research2021，9，10： | 3 |
| 10 | 2021 Chinese consensus on the diagnosis and management of primary immune thrombocytopenia in pregnancy显示文摘Immune thrombocytopenia(ITP)is an acquired disease characterized by isolated thrombocytopenia,which is one of the most common causes of thrombocytopenia during pregnancy.Women with ITP who have severe thrombocytopenia are at an increased risk for life-threatening obstetric complications.Therefore,we established this consensus statement on the diagnosis and management of ITP during pregnancy(detailed information is available in the Supplementary File,http://gffzz16e312a87a7141a5h59k6oof09co06nxk.ffgz.tsg.suse.edu.cn/A978). | Zhang Xiaohui Chen Fangping Chen Xiequn Cheng Yunfeng Fang Meiyun Feng Jianming Fu Haixia Gao Hong Han Yue He Aili Hou Ming Hu Yu Huang Ruibin Huang Wenrong Jing Zhicheng Kong Peiyan Liang Aibin Liang Meiying Liu Daihong Liu Junling Liu Lin Liu Xiaowei Ma Liangming Mei Heng Ni Heyu Niu Ting Peng Jun Qiao Jianlin Ren Jinhai Song Yongping Tang Liang V Tong Tong Wang Shaoyuan Wang Xin Wang Zhao Wei Hui Wu Depei Wu Guangsheng Xu Caigang Xu Xue Xu Yajing Yang Linhua Yang Renchi Yang Tonghua Yin Chenghong Yu Li Zhang Guangsen Zhang Lei Zhang Liansheng Zhang Xi Zhao Weili Zhao Yongqiang Zhou Daobin Zhou Hu Zhou Zeping Zhu Tienan Wang Jianliu Huang Xiaojun | 2022 | Chinese Medical Journal2022，，8： | 2 |
| 11 | Electrochemomechanical coupled behaviors of deformation and failure in electrode materials for lithium-ion batteries显示文摘The growing demands of lithium-ion batteries with high energy density motivate the development of high-capacity electrode materials. The critical issue in the commercial application of these electrodes is electrochemomechanical degradation accompanied with the large volume change, built-in stress, and fracture during lithiation and delithiation. The strong and complex couplings between mechanics and electrochemistry have been extensively studied in recent years. The multi-directional couplings, e.g.,(de)lithiation-induced effects and stress-regulated effects, require cooperation in the interdisciplinary fields and advance the theoretical and computational models. In this review, we focus on the recent work with topics in the electrochemomechanical couplings of deformation and fracture of conventional and alloying electrodes through experimental characterization, theoretical and computational models. Based on the point of view from mechanics, the strategies for alleviating the degradation are also discussed, with particular perspectives for component-interaction patterns in the composite electrodes. With interdisciplinary principles, comprehensive understanding of the electrochemomechanical coupled mechanism is expected to provide feasible solutions for low-cost, high-capacity, high-safety and durable electrodes for lithium-ion batteries. | LIANG HuanZi ZHANG XingYu YANG Le WU YiKun CHEN HaoSen SONG WeiLi FANG DaiNing | 2019 | Science China(Technological Sciences)2019，62，8： | 2 |
| 12 | Thickness evolution of commercial Li-ion pouch cells with siliconbased composite anodes and NCA cathodes显示文摘It is significant to monitor the thickness change of commercial Li-ion pouch cells that are assembled from Si-based electrodes and layered cathodes since the volume variation is critically linked with kinetic reaction mechanism and chemomechanical degradation. In this work, the single-point and full-field measurements are conducted on the thickness evolution of Si Ox/Cgraphite/lithium nickel-cobalt-aluminum oxide(Si Ox-G/NCA) batteries. It is found that an abnormal overshoot that has been rarely observed in the previous studies appears at the beginning of discharge, which is believed to be the combined results between the rapid expansion of NCA and the contraction of graphite related to the state of charge(SOC). Compared with the results of single-point measurement, the spatial displacement distribution obtained from three-dimensional(3D) scanning suggests the full-field thickness evolution of the entire cell scale, which is more feasible and efficient to provide full-field information for supporting pouch cell design and pack integration. | ZHANG XingYu HE Jie ZHOU Jiang CHEN HaoSen SONG WeiLi FANG DaiNing | 2021 | Science China(Technological Sciences)2021，64，1： | 2 |
| 13 | Application of fluorescence in situ hybridization in the detection of bladder transitional-cell carcinoma: A multi-center clinical study based on Chinese population显示文摘Objective:To evaluate the diagnostic value of fluorescence in situ hybridization(FISH)in bladder cancer.Methods:We enrolled healthy volunteers and patients who were clinically suspected to have bladder cancer and conducted FISH tests and cytology examinations from August 2007 to December 2008.Receiver operating characteristic(ROC)curve analysis was performed and the area under curve(AUC)values were calculated for both the FISH and urine cytology tests.Results:A cohort of 988 healthy volunteers was enrolled to establish a reference range for the normal population.A total of 4807 patients with hematuria were prospectively,randomly enrolled for the simultaneous analysis of urine cytology,FISH testing,and a final diagnosis as determined by the pathologic findings of a biopsy or a surgically-excised specimen.Overall,the sensitivity of FISH in detecting transitional-cell carcinoma was 82.7%,while that of cytology was 33.4%(p<0.001).The sensitivity values of FISH for non-muscle invasive and muscle invasive bladder transitional-cell carcinoma were 81.7%and 89.6%,respectively(p=0.004).The sensitivity values of FISH for low and high grade bladder cancer were 82.6%and 90.1%,respectively(p=0.002).Conclusion:FISH is significantly more sensitive than voided urine cytology for detecting bladder cancer in patients evaluated for gross hematuria at all cancer grades and stages.Higher sensitivity using FISH was obtained in high grade and muscle invasive tumors. | Liqun Zhou Kaiwei Yang Xuesong Li Yi Ding Dawei Mu Hanzhong Li Yong Yan Jinyi Li Dongwen Wang Wei Li Yulong Cong Jiangping Gao Kewei Ma Yajun Xiao Sheng Zhang Hongyi Jiang Weilie Hu Qiang Wei Xunbo Jin Zhichen Guan Qingyong Liu Danfeng Xu Xin Gao Yongguang Jiang Weimin Gan Guang Sun Qing Wang Yanhui Liu Jianquan Hou Liping Xie Xishuang Song Fengshuo Jin Jiafu Feng Ming Cai Zhaozhao Liang Jie Zhang Dingwei Ye Lin Qi Lulin Ma Jianzhong Shou Yuping Dai Jianyong Shao Ye Tian Shizhe Hong Tao Xu Chuize Kong Zefeng Kang Yuexin Liu Xun Qu Benkang Shi Shaobin Zheng Yi Lin Shujie Xia Dong Wei Jianbo Wu Weiling Fu Zhiping Wang Jianbo Liang | 2019 | Asian Journal of Urology2019，6，1： | 2 |
| 14 | Electrochemically triggered decoupled transport behaviors in intercalated graphite:From energy storage to enhanced electromagnetic applications显示文摘Pyrolytic graphite (PG) with highly aligned graphene layers,present anisotropic electrical and thermal transport behavior,which is attractive in electronic,electrocatalyst and energy storage.Such pristine PG could meeting the limit of electrical conductivity (~2.5×10^(4) S·cm^(−1)),although efforts have been made for achieving high-purity sp^(2) hybridized carbon.For manipulating the electrical conductivity of PG,a facile and efficient electrochemical strategy is demonstrated to enhance electrical transport ability via reversible intercalation/de-intercalation of AlCl_(4)^(-)into the graphitic interlayers.With the stage evolution at different voltages,variable electrical and thermal transport behaviors could be achieved via controlling AlCl_(4)^(-)concentrations in the PG because of substantial variation in the electronic density of states.Such evolution leads to decoupled electrical and thermal transport (opposite variation trend) in the in-plane and out-of-plane directions,and the in-plane electrical conductivity of the pristine PG (1.25×10^(4) S·cm^(−1)) could be massively promoted to 4.09×10^(4) S·cm(AlCl_(4)^(-)intercalated PG),much better than the pristine bulk graphitic papers used for the electrical transport and electromagnetic shielding.The fundamental mechanism of decoupled transport feature and electrochemical strategy here could be extended into other anisotropic conductive bulks for achieving unusual behaviors. | Ya Chen Kailun Zhang Na Li Wei Guan Zhiyuan Li Haosen Chen Shuqiang Jiao Weili Song | 2023 | International Journal of Minerals,Metallurgy and Materials2023，30，1： | 1 |
| 15 | Development of novel dental nanocomposites reinforced with polyhedral oligomeric silsesquioxane (POSS)显示文摘 | Xiaorong Wua Yi Sun Weili Xie Yanju Liu Xueyu Song | | 0，，： | 1 |
| 16 | Preparation and properties of ZnO nano-whiskers显示文摘By a novel controlled combustion synthesis method, a large amount of ZnO nano-whiskers with different morphologies like nanotetrapods, long-leg nanotetrapod and multipods, were prepared without any catalysts and additives in open air at high temperature. Their morphologies, structures and optical properties were in-vestigated by using SEM, XRD and PL spectrum. The possible growth mechanisms on the ZnO nano-whiskers were proposed in this paper. | SHI XiaoLing CAO MaoSheng ZHAO YuNa SONG WeiLi RONG JiLi | 2008 | Science China(Technological Sciences)2008，51，9： | 1 |
| 17 | Effect of abrasive particle concentration on preliminary chemical mechanical polishing of glass substrate显示文摘 | Zefang Zhang Weili Liu Zhitang Song | 2010 | Microelectronic Engineering2010，，11： | 1 |
| 18 | Modification of Band Gap of-SiC by N-Doping显示文摘 | Hongsheng Liu Xiaoyong Fang Weili Song | 2009 | Chinese Physics Letter2009，26，06： | 1 |
| 19 | High- temperature microwave absorption and evolutionary behavior of multiwalled carbon nanotube nanocomposite显示文摘 | Song Weili Cao Maosheng Hou Zhiling | 2009 | Scripta Materia- lia2009，61，2： | 1 |
| 20 | Specific Heat Anomaly of Lithium Sodium Niobate at Low Temperature显示文摘A differential scanning calorimetric(DSC)study of the crystal Li_(0.02)Na_(0.98)NbO_(3) was carried out in the temperature range from 120 to 300K.The specific heat changes anomalously at about 180K on cooling and about 260K on heating,implying a first order phase transition.The heat of transition ΔQ=(212±50)J/mol and the corresponding change in entropy AS=0.82J/mol.K.The thermal hysteresis of this transition is about 80K,in agreement with that previously obtained from the dielectric and pyroelectric measurements. | ZHANG Peilin ZHONG Weilie ZHAO Shaoxiang YANG Zhaohe CHEN Huanchu SONG Yongyuan | 1992 | Chinese Physics Letters1992，9，8： | 1 |
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