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| 1 | 甲状腺癌手术——Memorial Sloan-Kettering Cancer Center经验(一)显示文摘甲状腺切除术是甲状腺癌的标准治疗方式,可由普外科、耳鼻咽喉头颈外科、内分泌外科或肿瘤外科医生来完成。对肿瘤外科来讲,甲状腺外科主要有三个目的:完整切除单侧或双侧甲状腺腺叶,保留保护好甲状旁腺及其血供,避免喉上神经和喉返神经的损伤。 | Ziv Gil Snehal G. Patel 李平栋(译) 于振坤(译) | 2011 | 中华耳鼻咽喉头颈外科杂志2011,46,9: | 14 |
| 2 | Potential therapeutics specific to c-MET/RON receptor tyrosine kinases for molecular targeting in cancer therapy显示文摘遇见 c 的 proto-oncogenes 和 RON 的产品属于受体酷氨酸 kinases 的一个亚科显著地作出贡献到 tumorigenic 前进。在主要肿瘤,改变了调整被房间移植和矩阵侵略描绘的侵略生长的 c-MET/RON 表达式 transduces 信号。这些病原的特征为在癌症治疗指向 c-MET/RON 提供基础。在最后十年,各种各样的途径被调查了压制 c-MET/RON-transduced oncogenesis。在开发的治疗学之中, monoclonal 抗体(mAbs ) 和小分子的禁止者(SMI ) 作为有希望的候选人出现了。这些治疗学的候选人的机制是为幸存的 c-MET/RON 信号上的肿瘤相关性的混乱。对 hepatocyte 生长因素(AMG102 ) 特定、遇见 c 的 mAbs (MetMAb ) 是人性化并且能堵住遇见 c 的发信号,在异种皮移植在肿瘤生长的 vitro 和抑制导致肿瘤房间增长的抑制当模特儿。mAb AMG102 抵销 hepatocyte 生长因素并且在 vivo 提高各种各样的 chemotherapeutics 的 cytotoxicity 到肿瘤。AMG102 当前在为有先进稳固的肿瘤的病人的阶段 II 临床的试用。IMC-41A40 和 Zt/f2 是 RON 特定的 mAbs 那下面调整 RON 表情并且禁止导致 ligand 的 phosphorylation。两 mAbs 在老鼠禁止肿瘤生长由冒号和胰腺的癌症细胞调停了。对特定的 SMI 遇见 c (ARQ107 和 PF-02341066 ) 在临床的试用的各种各样的阶段。治疗学的功效也与象化合物那样的双禁止者被观察了我,它对 c-MET/RON 特定。然而,一个潜在的问题是到这些禁止者的获得的抵抗的出现。清楚地, c-MET/RON 治疗学的开发为以后与癌症作斗争提供机会和挑战。 | Ming-Hai WANG Snehal S PADHYE Sunny GUIN Qi MA Yong-qing ZHOU | 2010 | Acta Pharmacologica Sinica2010,31,9: | 10 |
| 3 | 甲状腺癌手术——Memorial Sloan-Kettering Cancer Center经验(二)显示文摘(接上期)
十、术后护理和并发症处理
术后并发症对有经验的术者来讲并不常见,可以通过上述外科技术得以避免。并发症的早期识别,尽早处理对保证手术效果也极为重要。除术者进行密切术后观察外,还需要多学科治疗组的其他成员也对这些情况提高警惕。甲状腺术后最严重的并发症是喉返神经损伤和低钙血症。其他不常见但也较严重的并发症有血肿、积液、喉上神经损伤和切口感染。 | Ziv Gil Snehal G.Patel | 2011 | 中华耳鼻咽喉头颈外科杂志2011,46,10: | 8 |
| 4 | Pharmacological Activation of Liver X Receptors Promotes Reverse Cholesterol Transport In Vivo显示文摘 | Snehal U. Naik Xun Wang Jaqueline S. Da Silva Michael Jaye Colin H. Macphee Muredach P. Reilly Jeffrey T. Billheimer George H. Rothblat Daniel J. Rader | 2006 | Circulation2006,,: | 2 |
| 5 | Automatically utilizing secondary source to align information across sources显示文摘 | Martin M Snehal T Craig A K | 2005 | AI Magazine Spe cial Issue on Semantic Integration2005,26,1: | 1 |
| 6 | Protective effect of curcumin on experimentally induced inflammation, hepatotoxicity and cardiotoxicity in rats: Evidence of its antioxidant property显示文摘 | Suresh R Naik Vishnu N Thakare Snehal R Patil | 2010 | Experimental and Toxicologic Pathology2010,,5: | 1 |
| 7 | Seismic behavior of slab-structural wall junction of RC building显示文摘In high seismic zone regions, slender reinforced concrete structural walls are commonly used in high-rise buildings as a main lateral load resisting element. These walls are very effective in limiting the lateral drift of the building due to their large in-plane stiffness. However, the presence of floor slabs influences the behavior of the shear wall. Also, the current design requirements do not account for the presence of floor slabs. To understand the behavior of wall-slab junctions and address the shortcomings of the current design requirements, the influence of two parameters, namely(a) aspect ratio and(b) longitudinal reinforcement ratio on the behavior is studied numerically. It is observed that the presence of floor slabs at different levels tends to partition the wall into squat wall panels between two consecutive floors. The wall-slab junctions show large stress concentrations arising from the strut action in the squat panels. It is also observed that the floor slabs can get significantly damaged near the wall-slab junction for lower vertical reinforcement ratios in the wall. Thus, the current codeprescribed minimum reinforcement in shear walls is not sufficient and needs to be revisited at for improved performance. | Snehal Kaushik Kaustubh Dasgupta | 2019 | Earthquake Engineering and Engineering Vibration2019,18,2: | 1 |
| 8 | Dynamic Contrast-Enhanced Magnetic Resonance Imaging as a Predictor of Outcome in Head-and-Neck Squamous Cell Carcinoma Patients With Nodal Metastases显示文摘 | Amita Shukla-Dave Nancy Y. Lee Jacobus F.A. Jansen Howard T. Thaler Hilda E. Stambuk Matthew G. Fury Snehal G. Patel Andre L. Moreira Eric Sherman Sasan Karimi Ya Wang Dennis Kraus Jatin P. Shah David G. Pfister Jason A. Koutcher | 2012 | International Journal of Radiation Oncology, Biology, Physics2012,,: | 1 |
| 9 | Correlation of a priori DCE-MRI and 1 H-MRS data with molecular markers in neck nodal metastases: Initial analysis显示文摘 | Jacobus F.A. Jansen Diane L. Carlson Yonggang Lu Hilda E. Stambuk Andre L. Moreira Bhuvanesh Singh Snehal G. Patel Dennis H. Kraus Richard J. Wong Ashok R. Shaha Jatin P. Shah Amita Shukla-Dave | 2012 | Oral Oncology2012,,: | 1 |
| 10 | Improved outcomes in patients with osteogenic sarcoma of the head and neck 显示文摘 | Snehal GP Paul M Andrew GH | 2002 | Cancer2002,95,7: | 1 |
| 11 | FRCS factors affecting blood Loss during percutaneous nephrolithotomy: prospective study显示文摘 | RAJESH KUKREJA MIHIR DESAI SNEHAL PATEL | 2004 | J Endourology2004,18,8: | 1 |
| 12 | TNM Staging of Cancers of the Head and Neck:Striving for Uniformity Among Diversity显示文摘 | Snehal GP Jatin PS | 2005 | Cancer J Clin2005,55,4: | 1 |
| 13 | FRCS factors affecting blood loss during percutaneous nephrolithotomy: prospective study 显示文摘 | Raj EK Mihir D Snehal P | 2004 | J Endou- rology2004,18,8: | 1 |
| 14 | Changes in the lumbar foramen following anterior interbody fusion with tapered or cylindrical cages显示文摘 | Mei W Snehal D Vaibhav B | | 0,,05: | 1 |
| 15 | Solitary Fibrous Tumors of the Head and Neck: a Clinicopathologie and Radiologie Review 显示文摘 | Ian Ganly Snehal GP Hilda ES | 2006 | Arch Otolaryngol Head Neck Surg2006,132,3: | 1 |
| 16 | Non-invasive imaging of PI3K/Akt/ mTOR signalling in cancer显示文摘 | Snehal M G Pritha R | 2012 | Am J Nucl Med Mol Imaging2012,2,4: | 1 |
| 17 | A rare occurrence of Langerhans cell histiocytosis in an adult 显示文摘 | Shevale V V Ekta K Snehal T | 2014 | J Oral Maxillofac Patho12014,18,3: | 1 |
| 18 | Pharmacological activation of liver X receptors promotes reverse cholesterol transport in vivo显示文摘 | Snehal U N Xun Wang Jaqueline S | 2006 | Circulation2006,113,: | 1 |
| 19 | Improved outcomes in patients with osteogenic sarcoma of the head and neck 显示文摘 | Snehal GP Paul M Andrew GH | 2002 | Cancer2002,95,7: | 1 |
| 20 | A Review on Nu- merical and Expermental Study of Screw Conveyor 显示文摘 | Jigar Patel Sumant Patel Snehal Patel | 2012 | Re- view Article2012,,6: | 1 |