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| 1 | Current status of clinical islet transplantation显示文摘Islet transplantation(IT) is today a well-established treatment modality for selected patients with type 1 diabetes mellitus(T1DM). After the success of the University of Alberta group with a modified approach to the immune protection of islets, the international experience grew along with the numbers of transplants in highly specialized centers. Yet, long-term analysis of those initial results from the Edmonton group indicated that insulin-independence was not durable and most patients return to modest amounts of insulin around the fifth year, without recurrent hypoglycemia events. Many phenomena have been identified as limiting factor for the islet engraftment and survival, and today all efforts are aimed to improve the quality of islets and their engrafting process, as well as more optimized immunosuppression to facilitate tolerance and ultimately, better long term survival. This brief overview presents recent progress in IT. A concise historical perspective is provided, along with the latest efforts to improve islet engraftment, immune protection and ultimately, prolonged graft survival. It is apparent that as the community continues to work together further optimizing IT, it is hopeful a cure for T1 DM will soon be achievable. | Andrew R Pepper Boris Gala-Lopez Oliver Ziff AM James Shapiro | 2013 | World Journal of Transplantation2013，3，4： | 3 |
| 2 | Mass transport of macromolecules within an in vitro model of supragingival plaque显示文摘 | Thurnheer T Gmir R Shapiro S | | 0，，03： | 2 |
| 3 | Combination therapy with low dose sirolimus and tacrolimus is synergistic in preventing spontaneous and recurrent autoimmune diabetes in nonobese diabetic mice 显示文摘 | Shapiro A M Suarez-Pinzon W L Power R | 2002 | Diabetologia2002，45，2： | 1 |
| 4 | Interactional Fairness Judgements:The Influence of Causal Accounts显示文摘 | SHAPIRO D L | 1987 | Social Justice Research1987，，1： | 1 |
| 5 | Adductor brevis myositis following tarnsobturator tape procedure: a case report and review of the literature 显示文摘 | DeSouza R Shapiro A Westney O L | 2007 | Int Urogynecol J Pelvic Floor Dysfunct2007，18，7： | 1 |
| 6 | Endothelin-1 in the human prostate tissue levels ,source of production and isometric tension studies 显示文摘 | Langenstror P Tang R Shapiro E | 1993 | J Urol1993，149，6： | 1 |
| 7 | Image segmentation techniques显示文摘 | Haralick R Shapiro L | 1985 | Journals of Computer Vision Graphics and Image Processing1985，29，： | 1 |
| 8 | Maximizing Cross-functional New Product Teams' Innovativeness and Constraint Adherence:A Conflict Communications Perspective显示文摘 | Lovelace K Shapiro D L Weingart L R | 2001 | Academy of Management Journal2001，44，4： | 1 |
| 9 | Universal vectors for operators on spaces of holomorphic functions显示文摘 | Gethner R M Shapiro J H | 1987 | Proc Amer Math Soc1987，100，2： | 1 |
| 10 | Regulation of fasted blood glucose by resistin显示文摘 | Banerjee R R Rangwala S M Shapiro J S | 2004 | Science2004，303，5661： | 1 |
| 11 | The alpha-adrenoceptor subtype mediating the tension of human prostatic smooth muscle显示文摘 | Lepor H Tang R Shapiro E | 1993 | Prostate1993，22，4： | 1 |
| 12 | Wrist loading patterns during pommel horse exercises显示文摘 | MARKOLF K L SHAPIRO M S MANDELBAUM B R etal | 1990 | J Bi omeeh1990，23，10： | 1 |
| 13 | Adaptation of HIV-1to human leukocyte antigen class I显示文摘 | Kawashima Y Pfafferott K Frater J Matthews P Payne R Addo M Gatanaga H Fujiwara M Hachiya A Koizumi H Kuse N Oka S Duda A Prendergast A Crawford H Leslie A Brumme Z Brumme C Allen T Brander C Kaslow R Tang J Hunter E Allen S Mulenga J Branch S Roach T John M Mallal S Ogwu A Shapiro R Prado J G Fidler S Weber J Pybus O G Klenerman P Ndung'u T Phillips R Heckerman D Harrigan P R Walker B D Takiguchi M Goulder P | 2009 | Nature2009，458，7238： | 1 |
| 14 | Subcutaneous immunoglobulin therapy by rapid push is preferred to infusion by pump= a retrospec tive analysis显示文摘 | Shapiro R | 2010 | J Clin Immunol2010，30，2： | 1 |
| 15 | Diagnosis and management of Duchenne muscular dystrophy, part 2: implementation of multidisciplinary care显示文摘 | Katharine Bushby Richard Finkel David J Birnkrant Laura E Case Paula R Clemens Linda Cripe Ajay Kaul Kathi Kinnett Craig McDonald Shree Pandya James Poysky Frederic Shapiro Jean Tomezsko Carolyn Constantin | 2010 | Lancet Neurology2010，，2： | 1 |
| 16 | Sonication of echo-contrast agent : A standardized and reproducible methed 显示文摘 | REISNER S A SHAPIRO J R SCHWARZ K Q | 1988 | J Cardiovasc Ultrasonography1988，7，4： | 1 |
| 17 | Non-line-of -sight singlescatter propagation model显示文摘 | Mark R Luettgen Jeffrey H Shapiro | 1991 | J Optical Society of America1991，8，： | 1 |
| 18 | The protective efficacy of polyvalent pneumococcal polysaccharide vaccine 显示文摘 | Shapiro E D Berg A T Austrian R | 1991 | N Engl J Med1991，325，21： | 1 |
| 19 | Oscillating field stimulation for complete spinal cord injury in humans: a phase 1 trial显示文摘 | Shapiro Borgens RB Pascuzzi R | 2005 | J Neurosurg Spine2005，2，1： | 1 |
| 20 | Spatial arrangements and associative behavior of species in an in vitro oral biofilm model显示文摘 | Guggenheim M Shapiro S Gmur R | 2001 | Appl Environ Microbiol2001，67，： | 1 |
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