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| 1 | Pure and Mg-doped self-assembled ZnO nano-particles for the enhanced photocatalytic degradation of 4-chlorophenol显示文摘A novel self-assembled pure and Mg doped ZnO nano-particles(NPs) were successfully synthesized by a simple low temperature co-precipitation method. The prepared photocatalysts were characterized by X-ray difraction, high resolution scanning electron microscopy, high resolution transmission electron microscopy, difuse reflectance spectroscopy and photoluminescence(PL) spectroscopy.The results indicated that the prepared photocatalysts showed high crystallinity with a uniform size distribution of the NPS. The degradation of cholorphenols is highly mandatory in today's scenario as they are afecting the environment adversely. Thus, the photocatalytic degradation of 4-chlorophenol(4-CP), a potent endocrine disrupting chemical in aqueous medium was investigated by both pure and Mg-doped ZnO NPs under UV-light irradiation in the present study. The influence of the Mg content on the structure,morphology, PL character and photocatalytic activity of ZnO NPs were investigated systematically. Furthermore,the efect of diferent parameters such as 4-CP concentration, photocatalyst amount, pH and UV-light wavelength on the resulting photocatalytic activity was investigated. | N.Clament Sagaya Selvam S.Narayanan L.John Kennedy J.Judith Vijaya | 2013 | Journal of Environmental Sciences2013，25，10： | 8 |
| 2 | Biosynthesis of silver nanoparticles by using mangrove plant extract and their potential mosquito larvicidal property显示文摘Objective:To identify the larvicidal activities of silver nano particles synthesised with Rhizophora mucronata(R.mucronata) leaf extract against the larvae of Aedes aegypti(Ae.aegypti) and Culex quinquefasciatus(Cx.quinquefasciatus).Methods:In vitro larvicidal activities such as LC50 and LC90 were assessed for the Ae.aegypti and Cx.quinquefasciatus larval species.Further, characterisation such as UV,XRD,FTIR and AFM analysis were carried out for the synthesised silver nano particles.Results:The LC50 value of the synthesised silver nano particle was identified as 0.585 and 0.891 mgg/L for Ae.aegypti and Cx.quinquefasciatus larvae respectively. Further,the LG90 values are also identified as 2.615 and 6.291 mg/L for Ae.aegypti and Cx. quinquefasciatus species respectively.The synthesised silver nanoparticles have maximum absorption at 420 nm with the average size of 60-95 nm.The XRD data showed 20 intense values with various degrees such as 37.10°,47.66°,63.97°and 70.01°.The FTIR data showed prominent peaks in(3 426.89,2 925.49,2 869.56,2 346.95,1 631.49,1 031.73,669.18 and 455.12) different ranges.Conclusions:The biosynthesis of silver nanoparticles with leaf aqueous extract of R. mucronata provides potential source for the larvicidal activity against mosquito borne diseases. | M Gnanadesigan M Anand S Ravikumar M Maruthupandy V Vijayakumar S Selvam M Dhineshkumar AK Kumaraguru | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，10： | 4 |
| 3 | 碳化硅与氟钛酸钾原位反应制备AA6061/TiC铝基复合材料的显微组织与力学性能表征(英文)显示文摘采用K_2TiF_6无机盐和SiC陶瓷颗粒与铝熔体原位反应制备不同含量TiC颗粒(0,2.5%,5%,质量分数)增强AA6061铝合金。为分解SiC释放碳原子,合金在高温下进行铸造,并保温一段时间。X射线衍射分析表明铝基复合材料中只生成TiC颗粒而未见其他金属间化合物。采用场发射扫描电子显微镜(FESEM)和背散射电子衍射(EBSD)分析AA6061/TiC复合材料的显微组织。结果表明原位生成的TiC颗粒分布均匀,界面清晰,结合良好,并具有立方、球形和六方等形状。EBSD图像表明TiC颗粒对复合材料具有明显的晶粒细化效果。TiC颗粒可提高铝基复合材料的显微硬度和抗拉强度。 | K.JESHURUN LIJAY J.DAVID RAJA SELVAM I.DINAHARAN S.J.VIJAY | 2016 | Transactions of Nonferrous Metals Society of China2016，26，7： | 4 |
| 4 | Antimicrobial and hemolytic activity of fish epidermal mucus Cynoglossus arel and Arius caelatus显示文摘Objective:To study the antimicrobial,hemolytic activity and immunomodulatory activity of fish epidermal mucus and their chemical constituents from Cynoglossus arel(C.arel) and Alius caelatus(A.caelatus).Mucus plays an important role in the prevention of colonization by parasites,bacteria and fungi.Methods:Epidermal mucus was obtained from two marine fishes,lyophilized and the chemical composition of epidermal mucus was analysed by FT-IR analysis.The in vitro antimicrobial activity against human pathogens(fungi,gram positive and gram-negative bacteria) and also the hemolytic activity and immunomodulatory activity were determined.Results:Totally ten human pathogens were tested against the fish mucus.Out of the ten pathogens,five pathogens have proved to be sensitive to the mucus.Maximum zone of inhibition was observed against Vibrio cholera(V.cholera)(9 mm and 2 mm in diameter),followed by Staphylococcus aureus(S.aureus) with a inhibition zone of(6 mm and 3 mm),Streptococcus areus(S.areus)(5 mm and 4 mm),Vibrio parahemolyticus(V.parahemolyticus)(4 mm and 5 mm) respectively.Conclusions:The present investigation has revealed that positive progresses in the fish mucus extracts against human pathogens and hemolytic activity.But further efforts are required for the purification and isolation of the active antimicrobial compounds in order to establish their possible applications. | Subramanian Bragadeeswaran Selvam Priyadharshini Kolandhasamy Prabhu Solomon Raj Sophia Rani | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，4： | 3 |
| 5 | 草药复方Bresol抵抗化合物48/80诱导的肥大细胞脱颗粒及组胺释放:促使肥大细胞稳定的一种非免疫机制(英文)显示文摘目的:研究一种草药复方制剂Bresol对于肥大细胞脱颗粒以及组胺释放的保护作用。方法:使用大鼠腹膜内肥大细胞,在体外经化合物48/80诱导肥大细胞脱颗粒及组胺释放,评估Bresol稳定肥大细胞的作用。结果:显微镜下正常对照组涂片显示较多完整的肥大细胞,有极少量的脱颗粒肥大细胞和微量的组胺释放。阳性对照组中用化合物48/80培养的肥大细胞出现了显著的肥大细胞脱颗粒现象以及高浓度的组胺释放。而100mg/L浓度的Bresol明显抑制了化合物48/80诱导的肥大细胞脱颗粒。此外,Bresol可有效抑制化合物48/80诱导的组胺释放,且抑制效果与剂量有关。结论:Bresol能够在体外抑制化合物48/80诱导的肥大细胞脱颗粒和组胺释放。本研究的发现可解释Bresol对多种过敏疾病有效可能是通过一种非免疫机制。 | Yathiraj Ashwini Mohamed Rafiq Gollapalle L.Viswanatha Subbanna Rajesh Selvam Senthilraja Mohammed Azeemuddin Suryakanth D.Anturlikar Paramesh Rangesh Pralhad S.Patki | 2012 | 中西医结合学报2012，10，6： | 3 |
| 6 | Fate of tetracycline, sulfonamide and fluoroquinolone resistance genes and the changes in bacterial diversity during composting of swine manure显示文摘 | Ammaiyappan Selvam Delin Xu Zhenyong Zhao Jonathan W.C. Wong | 2012 | Bioresource Technology2012，，： | 3 |
| 7 | 复合铸造制备稻壳灰增强AA6061铝合金及表征(英文)显示文摘稻壳灰(RHA)是一种有潜力的廉价铝基复合材料的增强颗粒。采用复合铸造方法制备不同稻壳灰含量(0,2%,4%,8%,质量分数)增强的AA6061铝合金复合材料。采用X射线衍射和扫描电镜对所制备复合材料进行表征。X射线衍射谱表明AA6061/RHA铝基复合材料中除RHA颗粒外未形成其他金属间化合物。扫描电镜图片表明RHA颗粒均匀分布在铝基体中。RHA基本分布在晶粒内部。此外,RHA颗粒与铝基体结合良好并形成清晰的界面。RHA颗粒的添加能提高铝基复合材料的显微硬度和抗拉强度。铝基复合材料的拉伸行为与其微观组织密切相关。 | J.ALLWYN KINGSLY GLADSTON N.MOHAMED SHERIFF I.DINAHARAN J.DAVID RAJA SELVAM | 2015 | Transactions of Nonferrous Metals Society of China2015，25，3： | 2 |
| 8 | Characterization of cytotoxic compound from marine sediment derived actinomycete Streptomyces avidinii strain SU4显示文摘Objective:To investigate the cytotoxic activity of actinomycete isolated from marine sediment.Methods:In the present study the DNA was isolated and the ITS region of 16s rRNA was amplified by polymerase chain reaction,using two universal bacterial primers,1492K(5'-GGTTACCTTG'TTAC GACTT-3')and Eubac27F(5'-AGAGTTTGATCCTGGCTC AG-3').The amplified products were purified using TIANgel mini purification kit,ligated to MD18-T simple vector(TaKaRa),and transformed into competent cells of Escherichia coli DH5α.16S rRNA gene fragment was sequenced using forward primer M13F(-47)and reverse primer M13R(-48).Blast search sequence similarity was found against the existing non-redundanl nucleotide sequence database thus,identified as Streptomyces sp SU,Streptomyces rubralavandulae strain SU1,Streptomyces cacaoi strain SU2,Streptomyces cavourensis strain SU3,Streptomyces avidinii strain SU4,Streptomyces globisporus strain SU5,Streptomyces variabilis strain SU6,Streptomyces coelicolor strain SU 7.Among the eight identified isolates,one actinomycete Streptomyces avidinii strain SU4 was selected for further study.Results:Crude extract of the actinomycete isolate exhibited IC_(50)in 64.5μg against Hep-2 cell line,250μg in VERO cell line.This value is very close to the criteria of cytotoxicity activity for the crude extracts,as established by the American National Cancer Institute(NCI)is in IC_(50)<30μg/mL.The CC MS analysis showed that the active principle might be 1,2-benzenedicarboxylic acid,bis(2-methylpropyl)ester(12.17%),isooctyl phthalate(15.29%)with the retention time 15.642 and 21.612,respectively.Conclusions:This study clearly proves that the marine sediment derived actinomycetes with bioactive metabolites can be expected to provide high quality biological material for high throughout biochemical and anticancer screening programs.These results help us to conclude that the potential of using metabolic engineering and post genomic approaches to isolate more bioactive compounds and make their possible commercial application is not far off. | Sudha S Masilamani Selvam M | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，10： | 2 |
| 9 | Composting of swine manure spiked with sulfadiazine, chlortetracycline and ciprofloxacin显示文摘 | Ammaiyappan Selvam Zhenyong Zhao Jonathan W.C. Wong | 2011 | Bioresource Technology2011，，： | 2 |
| 10 | Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A‐RIPK1‐dependent necroptosis显示文摘 | Sahar A. Saddoughi Salih Gencer Yuri K. Peterson Katherine E. Ward Archana Mukhopadhyay Joshua Oaks Jacek Bielawski Zdzislaw M. Szulc Raquela J. Thomas Shanmugam P. Selvam Can E. Senkal Elizabeth Garrett‐Mayer Ryan M. De Palma Dzmitry Fedarovich Angen Liu | 2012 | EMBO Mol Med2012，，1： | 2 |
| 11 | Multi-center evaluation of oxidation-reduction potential by the MiOXSYS in males with abnormal semen显示文摘According to the World Health Organization(WHO),oxidative stress(OS)is a significant contributor to male infertility.SeminalOS can be measured by a number of assays,all of which are either costly or time sensitive and/or require large semen volume andcomplex instrumentation.One less expensive alternative is to quantify the oxidation-reduction potential(ORP)with the MiOXSYS.In this international multi-center study,we assessed whether ORP levels measured by the MiOXSYS could distinguish semensamples that fall within the 2010 WHO normal reference values from those that do not.Semen samples were collected from 2092patients in 9 countries;ORP was normalized to sperm concentration(mV/10^6 sperm/ml).Only those samples with a concentration>1×10^6 sperm ml1 were in eluded.The results showed that 199 samples fell within the WHO no rmal refere nee range while theremaining 1893 samples did not meet one or more of the criteria.ORP was negatively correlated with all semen parameters(P <0.01)except volume.The area under the curve for ORP was 0.765.The ORP cut-off value(1.34 mV/10^6 sperm/ml)was able todifferentiate specimens with abnormal semen parameters with 98.1%sensitivity,40.6%specificity,94.7%positive predictivevalue(PPV)and 66.6%negative predictive value(NPV).When used as an adjunct to traditional semen analysis,ORP levels mayhelp identify altered functional status of spermatozoa caused by OS in cases of idiopathic male infertility and in male partners ofcouples sufferi ng recurre nt pregna ncy loss,and thereby directi ng these men to relevant medical therapies and lifestyle modificati ons. | Ashok Agarwal Manesh Kumar Panner Selvam Mohamed Arafa Hiroshi Okada Sheryl Homa Aideen Killeen Basak Balaban Ramadan Saleh Abdullah Armagan Shubhadeep Roychoudhury Suresh Sikka | 2019 | Asian Journal of Andrology2019，21，6： | 2 |
| 12 | Molecular modeling studies of repandusinic acid as potent small molecule for hepatitis B virus through molecular docking and ADME analysis显示文摘Background:Hepatitis B virus(HBV)has affected over 300 million people worldwide which causes to induce mostly liver disease and liver cancer.It is a member of the family Hepadnaviridae which is a small DNA virus with unusual characters like retroviruses.Generally,hepatoprotective drugs provoke some side effects in human beings.For the reason,this study aims to identify alternative drug molecules from the natural source of medicinal plants with smaller quantity of side effects than those conventional drugs in treating HBV.Methods:We developed computational methods for calculating drug and target binding resemblance using the Maestro v10.2 of Schrodinger suite.The target and ligand molecules were obtained from recognized databases.Ligand molecules of 40 phytoconstituents were retrieved from variety of plants after we executed crucial analyses such as molecular docking and absorption,distribution,metabolism,and excretion(ADME)analysis.Results:In the docking analysis,the natural analogues repandusinic acid showed better docking scores of-14.768 with good binding contacts.The remaining bioactive molecules corilagin,furosin,nirurin,iso-quercetin and gallocatechin also showed better docking scores.Conclusions:This computational analysis reveals that repandusinic acid is a suitable drug candidate for HBV.Therefore,we recommend that this analogue is suitable in further exploration using in vitro studies. | Vijayakumar Subramaniyan Reetha Sekar Arulmozhi Praveenkumar Rajalakshmi Selvam | 2019 | Quantitative Biology2019，7，4： | 2 |
| 13 | Speciation of heavy metals during co-composting of sewage sludge with lime显示文摘 | WONG J W C SELVAM A | 2006 | Chemosphere2006，63，6： | 1 |
| 14 | Para selective t butyla tion of phenol over mesoporous H AIMCM 41显示文摘 | Sakthivel A Badamali S K Selvam P | 2000 | Micro Meso Mater2000，39，3： | 1 |
| 15 | TCP performance analysis for mobile Ad Hoc network using on-demand rout- ing protocols显示文摘 | Kathiravan K Thamarai S S Selvam A | 2007 | Ubiquitous Computing and Communication Journal2007，2，2： | 1 |
| 16 | 查看详情显示文摘 | Zampieri A Kullmann S Selvam T Bauer J Schwieger W Sieber H Fey T Greil P | | 0，，： | 1 |
| 17 | Chemoselective reduction of a,β-unsaturated carbonyls over novel mesoporous CoHMA molecular sieves under hydrogen transfer conditions显示文摘 | SELVAM P SONAVANE S U MOHAPATRA S K | 2004 | Adv Synth Catal2004，346，： | 1 |
| 18 | Transdermal drug delivery systems for antihypertensive drugs-a review 显示文摘 | Selvam RP Singh AK Sivakumar T | 2010 | lnt JPharm BiomedRes2010，1，1： | 1 |
| 19 | Surface characterisation of anodic films of Pb-Sn alloy electrodes:the effect of Sn on the photeelectrochemical properties显示文摘 | MUKHOPADHYAY I SELVAM P SHARON M | 1997 | Materials Chemistry and Physics1997，49，2： | 1 |
| 20 | Encapsulation of Fe2O3 nanoparticles in periodic mesoporous materials 显示文摘 | Selvam P | 2001 | Mater Phys Mech2001，4，： | 1 |
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