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| 1 | 新型压接式IGBT模块的结构设计与特性分析显示文摘介绍了一种新型压接式绝缘栅双极型晶体管(Insulated Gate Bipolar Transistor,简称IGBT)模块的内部结构设计,分析其相对于传统IGBT模块的优势,并通过静态和动态测试分析了其电气性能特点,展示了其良好的特性以及广阔的应用范围。 | 窦泽春 Rupert Stevens 忻兰苑 刘国友 徐凝华 | 2013 | 机车电传动2013,,1: | 15 |
| 2 | 104例老年骨质疏松性骨盆骨折的治疗——骨水泥型经髂骨螺钉内固定系统介绍显示文摘目的探讨骨水泥型经髂骨螺钉内固定系统(TIFI)治疗老年骨质疏松性骨盆骨折的方法。方法回顾性分析2004年1月至2014年11月期间收治的104例年龄≥59岁的骨盆骨折患者资料。男11例,女93例;年龄为59~94岁,平均(77.5±7.6)岁。骨折根据Ptommens分型:I型31例,Ⅱ型39例,Ⅲ型19例,Ⅳ型15例。致伤原因:平地摔伤89例,从低于3m高处摔伤8例,无明确外伤史7例。保守治疗65例;手术治疗39例,其中17例患者采用骨水泥型TIFI固定治疗,将宁心钉和SchalIZ钉从髂后卜棘到髂前下棘置入,并固定于髋臼上方。结果65例保守治疗患者出院当天活动度:坐轮椅1例,平地行走26例,可上下楼8例,未记录30例。39例手术治疗患者出院当天活动度:坐轮椅6例,平地行走26例,可上下楼1例,未记录6例。34例Schanz钉固定患者中,有2例固定髂骨时出现螺钉穿透骶髂关节。16例Schanz钉结合骨水泥固定患者中,未观察到骨水泥溢出至骶髂关节。Schanz钉髂骨置钉深度平均为(100±20)mm,连接杆的长度平均为(62±16)mm。17例采用TIFI固定的患者中,2例术后出现血肿,I例出现浅表伤口感染,未出现深层组织感染或内固定感染。结论老午骨质疏松性骨盆骨折可根据Rommens分型来选择治疗方式。骨水泥型TIFI固定是~一种治疗老年骨质疏松性骨笳骨折的微创、可靠方法。 | Paul Schmitz Stephan Luedeek 王博炜 Rupert Schupfner Michael Worlieek Michael Nerlich Michael Bernhard Muller | 2017 | 中华创伤骨科杂志2017,19,5: | 10 |
| 3 | Incidence and analysis of radial head and neck fractures显示文摘AIM: To investigate several complications like persistent radial head dislocation, forearm deformity, elbow stiffness and nerve palsies, associated with radial head fractures. METHODS: This study reviewed the clinical records and trauma database of this level Ⅰ Trauma Center and identified all patients with fractures of the radial head and neck who where admitted between 2000 and 2010. An analysis of clinical records revealed 1047 patients suffering from fractures of the radial head or neck classified according to Mason. For clinical examination, range of motion, local pain and overall outcome were assessed. RESULTS: The incidence of one-sided fractures was 99.2% and for simultaneous bilateral fractures 0.8%. Non-operative treatment was performed in 90.4%(n = 947) of the cases, surgery in 9.6%(n = 100). Bony union was achieved in 99.8%(n = 1045) patients. Full satisfaction was achieved in 59%(n = 615) of the patients. A gender related significant difference(P = 0.035) in Mason type distribution-type Ⅲ fractures were more prominent in male patients vs type Ⅳ fractures in female patients-was observed in our study population. CONCLUSION: Mason typeⅠfractures can be treated safe conservatively with good results. In type Ⅱ to Ⅳ surgical intervention is usually considered to be indicated. | Florian M Kovar Manuela Jaindl Gerhild Thalhammer Schuster Rupert Patrick Platzer Georg Endler Ines Vielgut Florian Kutscha-Lissberg | 2013 | World Journal of Orthopedics2013,4,2: | 9 |
| 4 | Primary sclerosing cholangitis as an independent risk factor for colorectal cancer in the context of inflammatory bowel disease: A review of the literature显示文摘To examine and evaluate recent evidence regarding the epidemiology, pathogenesis and management of colorectal cancer(CRC) development in inflammatory bowel disease(IBD)-primary sclerosing cholangitis(PSC) patients. Using the PubMed database, a literature search was conducted for relevant articles in English from the past 10 years. Relevant studies investigating PSC as a risk factor for CRC in IBD in the context of incidence and prevalence, pathogenesis, prevention and prognosis were included in this review. Recent evidence increasingly points to PSC as a significant risk factor in the development of CRC in patients with concomitant IBD. PSC may be an important risk factor for CRC in different populations worldwide. The mechanism for this increase in risk is still unclear. The efficacy of UDCA as a chemopreventive agent remains controversial. Liver transplantation does not halt the development of CRC, although there is not enough evidence to suggest that it is associated with increased incidence of CRC. While routine colonoscopic surveillance should be performed in patients with concurrent PSC and IBD, more high-level evidence is required to support the benefits of the procedure. While many new developments have taken place in the last decade, the pathogenesis and optimal management of CRC development in IBD-PSC patients remain unclear. | Rosy Wang Rupert Leong | 2014 | World Journal of Gastroenterology2014,20,27: | 8 |
| 5 | 高功率密度IGBT模块的研发与特性分析显示文摘基于现有标准DMOS设计技术,通过优化高压IGBT&FRD芯片及其模块结构,降低芯片功耗、模块寄生电感和模块热阻,改善模块散热,提高最高工作温度。研究开发了高功率密度1 500 A/3 300 V、1 200 A/4 500 V及750 A/6 500 V IGBT模块,满足轨道交通的应用要求。 | 刘国友 覃荣震 黄建伟 Ian Deviny 罗海辉 Rupert Stevens 吴义伯 | 2014 | 机车电传动2014,,2: | 8 |
| 6 | 思维、技术与学习综述(下)显示文摘本文首先对综述中用到的关键术语进行了界定,并讨论了思维技能、学习和技术三者之间的联系;然后从讨论一般思维技能是否存在的问题入手,针对思维技能能否被教授的问题进行了理论和实证的分析;接着对技术在思维技能教学中的作用进行了讨论,并认为信息和通讯技术(ICT)在思维技能教学中的作用方式主要有三种:作为导师或者教学机器、提供思维工具以及支持学习性对话。最后为使用技术支持思维技能的教学制定了指南,并评估了该领域的研究趋势及其对教育实践的启示。 | Rupert Wegerif 魏晓玲 吉喆 钟洪蕊 | 2009 | 远程教育杂志2009,27,6: | 7 |
| 7 | Incidence and Phenotype of Inflammatory Bowel Disease Based on Results From the Asia-Pacific Crohn’s and Colitis Epidemiology Study显示文摘 | Siew C. Ng Whitney Tang Jessica Y. Ching May Wong Chung Mo Chow A.J. Hui T.C. Wong Vincent K. Leung Steve W. Tsang Hon Ho Yu Mo Fong Li Ka Kei Ng Michael A. Kamm Corrie Studd Sally Bell Rupert Leong H. Janaka de Silva Anuradhani Kasturiratne M.N.F. Mufeen | 2013 | Gastroenterology2013,,1: | 6 |
| 8 | 碳化硅器件挑战现有封装技术显示文摘碳化硅(SiC)器件的新特性和移动应用的功率密度要求给功率器件的封装技术提出了新的挑战。现有功率器件的封装技术主要是在硅基的绝缘栅双极晶体管(Insulated Gate Bipolar Transistor,IGBT)和金属氧化物半导体场效应晶体管(Metal Oxide Semiconductor Field Effect Transistor,MOSFET)等基础上发展起来的,并一直都在演进,但这些渐进改良尚不足以充分发挥SiC器件的性能,因而封装技术需要革命性的进步。在简述现有封装技术及其演进的基础上,主要从功率模块的角度讨论了封装技术的发展方向。同时讨论了功率模块的新型叠层结构以及封装技术的离散化、高温化趋势,并对SiC器件封装技术的发展方向做出了综合评估。 | 曹建武 罗宁胜 Pierre Delatte Etienne Vanzieleghem Rupert Burbidge | 2022 | 电子与封装2022,22,2: | 6 |
| 9 | Gastroenterologist perceptions of faecal microbiota transplantation显示文摘AIM: To explore gastroenterologist perceptions towards and experience with faecal microbiota transplantation(FMT).METHODS: A questionnaire survey consisting of 17 questions was created to assess gastroenterologists' attitude towards and experience with FMT. This was anonymously distributed in hard copy format amongst attendees at gastroenterology meetings in Australia between October 2013 and April 2014. Basic descriptive statistical analyses were performed.RESULTS: Fifty-two clinicians participated. Twenty one percent had previously referred patients for FMT,8% more than once. Ninety percent would refer patients with Clostridium difficile infection(CDI) for FMT if easily available,37% for ulcerative colitis,13% for Crohn's disease and 6% for irritable bowel syndrome. Six percent would not refer any indication,including recurrent CDI. Eighty-six percent would enroll patients in FMT clinical trials. Thirty-seven percent considered the optimal mode of FMT administration transcolonoscopic,17% nasoduodenal,13% enema and 8% oral capsule. The greatest concerns regarding FMT were: 42% lack of evidence,12% infection risk,10% non infectious adverse effects/lack of safety data,10% aesthetic,10% lack of efficacy,4% disease exacerbation,and 2% inappropriate use; 6% had no concerns. Seventy seven percent believed there is a lack of accessibility while 52% had an interest in learning how to provide FMT. Only 6% offered FMT at their institution.CONCLUSION: Despite general enthusiasm,most gastroenterologists have limited experience with,or access to,FMT. The greatest concerns were lack of supportive evidence and safety issues. However a significant proportion would refer indications other than CDI for FMT despite insufficient evidence. These data provide guidance on where education and training are required. | Sudarshan Paramsothy Alissa J Walsh Thomas Borody Douglas Samuel Johan van den Bogaerde Rupert WL Leong Susan Connor Watson Ng Hazel M Mitchell Nadeem O Kaakoush Michael A Kamm | 2015 | World Journal of Gastroenterology2015,21,38: | 5 |
| 10 | Epidemiology of inflammatory bowel disease in South America: A systematic review显示文摘BACKGROUND The worldwide epidemiology of inflammatory bowel disease(IBD)is rapidly changing.Increasing Crohn’s disease(CD)and ulcerative colitis(UC)incidence and prevalence have been recorded in developing regions such as Asia,Africa and Eastern Europe where it was previously thought to be uncommon.Whether this is also the case in South America is not well known.Demonstration that developing regions worldwide have increasing IBD incidence would indicate that environmental change plays a significant role in the development of IBD.AIM To report the incidence,prevalence and disease characteristics of CD and UC within the South American continent.METHODS A systematic review was conducted by searching published studies in major international and regional databases(MEDLINE,EMBASE and Scopus)between January 1990 and December 2018.Outcomes considered were incidence,prevalence,phenotype,environmental and genetic factors,ethnicity and gender.A pair of independent reviewers screened and reviewed all identified articles.RESULTS One hundred and sixty two citations were initially retrieved with 18 studies included in this systematic review.The majority of included studies were from Brazil(n=13,72%).The incidence of UC ranged from 4.3-5.3/100000 personyears whilst the incidence of CD ranged from 0.74-3.5/100000 person-years.Prevalence ranged from 15.0-24.1/100000 inhabitants for UC and from 2.4-14.1/100000 inhabitants for CD.The incidence and prevalence of both UC and CD has increased significantly in Brazil over the past 21 years.Pancolitis was the most common disease distribution in patients with UC whilst colonic involvement was the most common distribution in CD.People residing in urban areas were at higher risk of developing both CD and UC.CONCLUSION The IBD burden in South America is increasing at a rate possibly even greater than other developing regions around the world.There is a paucity of highquality epidemiological studies and further robust and representative data are required to further explore modifiable risk factors and disease phenotypes. | Sriharan Selvaratnam Santiago Gullino Lisa Shim Eric Lee Alice Lee Sudarshan Paramsothy Rupert W Leong | 2019 | World Journal of Gastroenterology2019,25,47: | 5 |
| 11 | Epidemiological studies of migration and environmental risk factors in the inflammatory bowel diseases显示文摘Inflammatory bowel diseases(IBD)are idiopathic chronic diseases of the gastrointestinal tract well known to be associated with both genetic and environmental risk factors.Permissive genotypes may manifest into clinical phenotypes under certain environmental influences and these may be best studied from migratory studies.Exploring differences between first and second generation migrants may further highlight the contribution of environmental factors towards the development of IBD.There are few opportunities that have been offered so far.We aim to review the available migration studies on IBD,evaluate the known environmental factors associated with IBD,and explore modern migration patterns to identify new opportunities and candidate migrant groups in IBD migration research. | Yanna Ko Rhys Butcher Rupert W Leong | 2014 | World Journal of Gastroenterology2014,20,5: | 5 |
| 12 | Tests to measure the quality of spermatozoa at spermiation显示文摘这评论到评论修订世界健康组织() 象它用手的精液分析在 spermiation 与一个精子的特征相关。目的修订用手没有任何限制,包括改进“精液分析的质量”到临床的使用。而且,手册声明精液分析可能为(a) 是有用的“调查男富饶地位”和(b) “监视精子发生在期间并且跟随男富饶规定。“如果呼喊的精子的分析为在(b) 描述的目的被打算,那么,在 spermiation 是反常的房间不管多么必须被识别。这份报纸拿手册不识别的位置在 spermiation 估计精子的质量的方法。相反,它使用通过颈的粘液或在授精的地点附近到达的精子的一个“标准答案”。尽管这个标准为画考虑一个个人能使妊娠的概率的结论他的搭挡是适当的,它不为学习睾丸本身的病是适当的。此处,在 WHO 手册介绍的精子质量的措施是关于在随后变得反常的 spermiation 对那些是反常的精子的察觉的 critiqued。优秀评价基于能动或“可行”的精子的百分比是无意义的。在 spermiation 定义精子的其他的优秀属性在这份报纸被介绍。在结论,根据单个呼喊的精子的优秀属性,对在 spermiation 的精子的质量的评价最好通过(a)的申请被完成为精子质量和(b)的词法评估的一个新范例评估的现代分析技术在一件足够的样品,在每个精子的几个适当独立属性以便更精确地识别反常精子的比例。 | Rupert P. Amann | 2010 | Asian Journal of Andrology2010,12,1: | 5 |
| 13 | Current application of proteomics in biomarker discoveryfor inflammatory bowel disease显示文摘Recently, the field of proteomics has rapidly expanded in its application towards clinical research with objectives ranging from elucidating disease pathogenesis to discovering clinical biomarkers. As proteins govern and/or reflect underlying cellular processes, the study of proteomics provides an attractive avenue for research as it allows for the rapid identification of protein profiles in a biological sample. Inflammatory bowel disease(IBD) encompasses several heterogeneous and chronic conditions of the gastrointestinal tract. Proteomic technology provides a powerful means of addressing major challenges in IBD today, especially for identifying biomarkers to improve its diagnosis and management. This review will examine the current state of IBD proteomics research and its use in biomarker research. Furthermore, we also discuss the challenges of translating proteomic research into clinically relevant tools. The potential application of this growing field is enormous and is likely to provide significant insights towards improving our future understanding and management of IBD. | Patrick PY Chan Valerie C Wasinger Rupert W Leong | 2016 | World Journal of Gastrointestinal Pathophysiology2016,7,1: | 5 |
| 14 | One-Year Outcomes of the DA VINCI Study of VEGF Trap-Eye in Eyes with Diabetic Macular Edema显示文摘 | Diana V. Do Quan Dong Nguyen David Boyer Ursula Schmidt-Erfurth David M. Brown Robert Vitti Alyson J. Berliner Bo Gao Oliver Zeitz Rene Ruckert Thomas Schmelter Rupert Sandbrink Jeff S. Heier | 2012 | Ophthalmology2012,,8: | 4 |
| 15 | 植物光呼吸途径及其支路研究进展显示文摘[目的]光呼吸是植物重要的代谢途径之一,该过程要消耗大量能量从而降低光合效率,这种效果在C3植物中比C4植物中更明显。抑制光呼吸成为C3植物高光合效率的研究方向之一,为了解光呼吸研究现状。[方法]采用文献综述法对国内外光呼吸研究最新报道进行跟踪。[结果]对光呼吸途径的代谢机制、光呼吸重要生理功能及光呼吸支路最新研究进展做了综述。[结论]一种光呼吸支路的建立对C3植物光合效率提高及产量提高起到较好效果。 | 张树伟 王霞 马燕斌 李换丽 韩渊怀 Rupert Fray 吴霞 王新胜 | 2016 | 山西农业大学学报(自然科学版)2016,36,12: | 3 |
| 16 | 思维、技术与学习综述(上)显示文摘本文首先对综述中用到的关键术语进行了界定,并讨论了思维技能、学习和技术三者之间的联系;然后从讨论一般思维技能是否存在的问题入手,针对思维技能能否被教授的问题进行了理论和实证的分析;接着对技术在思维技能教学中的作用进行了讨论,并认为信息和通讯技术(ICT)在思维技能教学中的作用方式主要有三种:作为导师或者教学机器、提供思维工具以及支持学习性对话。最后为使用技术支持思维技能的教学制定了指南,并评估了该领域的研究趋势及其对教育实践的启示。 | Rupert Wegerif 魏晓玲 吉喆 钟洪蕊 | 2009 | 远程教育杂志2009,27,5: | 3 |
| 17 | The DA VINCI Study: Phase 2 Primary Results of VEGF Trap-Eye in Patients with Diabetic Macular Edema显示文摘 | Diana V. Do Ursula Schmidt-Erfurth Victor H. Gonzalez Carmelina M. Gordon Michael Tolentino Alyson J. Berliner Robert Vitti Rene Rückert Rupert Sandbrink David Stein Ke Yang Karola Beckmann Jeff S. Heier | 2011 | Ophthalmology2011,,9: | 3 |
| 18 | Nonlinear frequency conversion in optical nanoantennas and metasurfaces:materials evolution and fabrication显示文摘Nonlinear frequency conversion is one of the most fundamental processes in nonlinear optics.It has a wide range of applications in our daily lives,including novel light sources,sensing,and information processing.It is usually assumed that nonlinear frequency conversion requires large crystals that gradually accumulate a strong effect.However,the large size of nonlinear crystals is not compatible with the miniaturisation of modern photonic and optoelectronic systems.Therefore,shrinking the nonlinear structures down to the nanoscale,while keeping favourable conversion efficiencies,is of great importance for future photonics applications.In the last decade,researchers have studied the strategies for enhancing the nonlinear efficiencies at the nanoscale,e.g.by employing different nonlinear materials,resonant couplings and hybridization techniques.In this paper,we provide a compact review of the nanomaterials-based efforts,ranging from metal to dielectric and semiconductor nanostructures,including their relevant nanofabrication techniques. | Mohsen Rahmani Giuseppe Leo Igal Brener Anatoly V. Zayats Stefan A. Maier Costantino De Angelis Hoe Tan Valerio Flavio Gili Fouad Karouta Rupert Oulton Kaushal Vora Mykhaylo Lysevych Isabelle Staude Lei Xu Andrey E. Miroshnichenko Chennupati Jagadish Dragomir N. Neshev | 2018 | Opto-Electronic Advances2018,1,10: | 3 |
| 19 | Evaluation of the string test for the detection of Helicobacter pylori显示文摘AIM: Helicobacter pylori can be diagnosed by invasive ornon-invasive tests but to obtain bacteria for culture andantibiotic susceptibility testing, an upper GI endoscopy isoften required. The string test may be a minimally-invasivealternative method of obtaining H. pylori samples. This studyevaluates the sensitivity and specificity of the string test inthe diagnosis of H. pylori in comparison with endoscopicmeans of diagnosis.METHODS: This was a prospective open comparative studyof patients with dyspepsia with endoscopy-based tests asgold standard (defined as a positive CLO test and antralhistology). Fasting patients swallowed the encapsulated-string(Entero-test Hp), which was withdrawn after 1 hour. Thegastric juice from the string was plated onto H. pylori-selectivemedia for culture. Helicobacter pylori was identified by typicalcolony morphology, gram stain and biochemical test results.RESULTS: Thirty dyspeptic patients were recruited of whom21 (70 %) were positive for H. pylori according to the goldstandard. The sensitivity, specificity, positive predictive value,and negative predictive value for the string test were 38 %,100 %, 100 % and 41% respectively, and for endoscopicbiopsies 81%, 100 %, 100 %, 69 % respectively (P=0.004).Logistic regression showed that only abundant growthdensity from endoscopic biopsy cultures to be a predictor ofa positive string test (P=0.018).CONCLUSION: The string test is an alternative method toendoscopy in obtaining H. pylori but has a low sensitivitycompared to endoscopic biopsies. | Rupert WL Leong Ching C Lee Thomas KW Ling WaiK Leung Joseph JY Sung | 2003 | World Journal of Gastroenterology2003,9,2: | 3 |
| 20 | 职业教育与高等教育:问题、关注点和发展前景显示文摘从历史的角度来说,职业教育和高等教育源自截然不同的教育传统,大学一般生产系统的科学知识,而职业教育则提供某一特定职业的培训。随着时间的推移,这两者之间的关系也受到了社会经济发展过程的影响。在世界范围内,一个国家之内的精英高等教育机构、大众化高等教育机构、多科技术学院以及不同层次的职业教育机构间形成了复杂的关系。即使在都是以资本主义经济为主体的德国和英国等欧盟国家,也采用了不同的高等教育和职业教育实施方法。 | Rupert Maclean | 2007 | 职业技术教育2007,28,18: | 3 |