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| 1 | Kinetics and isotherms of Neutral Red adsorption on peanut husk显示文摘Adsorption of Neutral Red (NR) onto peanut husk in aqueous solutions was investigated at 295 K. Experiments were carried out as function of pH, adsorbent dosage, contact time, and initial concentration. The equilibrium adsorption data were analyzed by Langmuir, Freundlich, Temkin, Dubinin-Radushkevich, and Toth isotherm models. The results indicated that the Toth and Langmuir models provided the best correlation of the experimental data. The adsorption capacity of peanut husk for the removal of NR was determined with the Langmuir and found to be 37.5 mg/g at 295 K. The adsorption kinetic data were modeled using the pseudo-first order, pseudo-second order, and intra-particle diffusion kinetic equations. It was seen that the pseudo-first order and pseudo-second order kinetic equations could describe the adsorption kinetics. The intraparticle diffusion model was also used to express the adsorption process at the two-step stage. It was implied that peanut husk may be suitable as adsorbent material for adsorption of NR from aqueous solutions. | Runping HAN Mingsheng TANG | 2008 | Journal of Environmental Sciences2008，20，9： | 16 |
| 2 | Integrative lipidomic and transcriptomic study unravels the therapeutic effects of saikosaponins A and D on non-alcoholic fatty liver disease显示文摘Nonalcoholic fatty liver disease(NAFLD)has become one of the most prominent causes of chronic liver diseases and malignancies.However,few therapy has been approved.Radix Bupleuri(RB)is the most frequently used herbal medicine for the treatment of liver diseases.In the current study,we aim to systemically evaluate the therapeutic effects of saikosaponin A(SSa)and saikosaponin D(SSd),the major bioactive monomers in RB,against NAFLD and to investigate the underlying mechanisms.Our results demonstrated that both SSa and SSd improved diet-induced NAFLD.Integrative lipidomic and transcriptomic analysis revealed that SSa and SSd modulated glycerolipid metabolism by regulating related genes,like Lipe and Lipg.SSd profoundly suppressed the fatty acid biosynthesis by downregulating Fasn and Acaca expression and promoted fatty acid degradation by inducing Acox1 and Cpt1 a expression.Bioinformatic analysis further predicted the implication of master transcription factors,including peroxisome proliferator-activated receptor alpha(PPARα),in the protective effects of SSa and SSd.These results were further confirmed in vitro in mouse primary hepatocytes.In summary,our study uncoded the complicated mechanisms underlying the promising anti-steatosis activities of saikosaponins(SSs),and provided critical evidence inspiring the discovery of innovative therapies based on SSa and SSd for the treatment of NAFLD and related complications. | Xiaojiaoyang Li Junde Ge Yajing Li Yajie Cai Qi Zheng Nana Huang Yiqing Gu Qi Han Yunqian Li Rong Sun Runping Liu | 2021 | Acta Pharmaceutica Sinica B2021，11，11： | 15 |
| 3 | Adsorption performance of CMK-3 and C-FDU-15 in NO removal at low temperature显示文摘CMK-3 and C-FDU-15 samples were synthesized using hard-templating and evaporationinduced self-assembly(EISA)methods,respectively.The pore structures of CMK-3 and CFDU-15 as well as commercial activated carbon were characterized by means of X-ray diffraction,field emission scanning electron microscopy,transmission electron microscopy,and N2 adsorption–desorption.Adsorption of NO was investigated by means of thermogravimetric analysis,temperature-programmed desorption of NO+O2,and in situ diffuse reflectance Fourier transform infrared spectroscopy.The results show that the CMK-3 and C-FDU-15 materials possessed ordered and uniform structures.The coadsorption capacity of NO and O2 decreased in the sequence CMK-3(88.6 mg/g)>C-FDU-15(71.7 mg/g)>AC(25.3 mg/g).There were two main adsorption species on CMK-3 and CFDU-15:nitrite and nitrate.Nitrite is converted to nitrate easily.However,the adsorption species were more complex on AC,with nitrite being the main species.Moreover,CMK-3 and C-FDU-15 exhibit excellent regeneration efficiency compared with AC.The excellent NO adsorption performance of CMK-3 and C-FDU-15 was associated with their ordered mesoporous structures and high surface areas.The research provides more options for NO adsorption in the future. | Runping Wu Qing Ye Kai Wu Shuiyuan Cheng Tianfang Kang Hongxing Dai | 2020 | Journal of Environmental Sciences2020，32，1： | 2 |
| 4 | Exploration of spatial and temporal characteristics of PM2.5 concentration in Guangzhou, China using wavelet analysis and modified land use regression model显示文摘This article attempts to detail time series characteristics of PM2.5 concentration in Guangzhou(China)from 1 June 2012 to 31 May 2013 based on wavelet analysis tools,and discuss its spatial distribution using geographic information system software and a modified land use regression model.In this modified model,an important variable(land use data)is substituted for impervious surface area,which can be obtained conveniently from remote sensing imagery through the linear spectral mixture analysis method.Impervious surface has higher precision than land use data because of its sub-pixel level.Seasonal concentration pattern and day-by-day change feature of PM2.5 in Guangzhou with a micro-perspective are discussed and understood.Results include:(1)the highest concentration of PM2.5 occurs in October and the lowest in July,respectively;(2)average concentration of PM2.5 in winter is higher than in other seasons;and(3)there are two high concentration zones in winter and one zone in spring. | Fenglei Fan Runping Liu | 2018 | Geo-Spatial Information Science2018，21，4： | 2 |
| 5 | Bioengineering of nano metal-organic frameworks for cancer immunotherapy显示文摘Immunotherapy techniques,such as immune checkpoint inhibitors,chimeric antigen receptor(CAR)T cell therapies and cancer vaccines,have been burgeoning with great success,particularly for specific cancer types.However,side effects with fatal risks,dysfunction in tumor microenvironment and low immune response rates remain the bottlenecks in immunotherapy.Nano metal-organic frameworks(nMOFs),with an accurate structure and a narrow size distribution,are emerging as a solution to these problems.In addition to their function of temporospatial delivery,a large library of their compositions,together with flexibility in chemical interaction and inherent immune efficacy,offers opportunities for various designs of nMOFs for immunotherapy.In this review,we overview state-of-the-art research on nMOFs-based immunotherapies as well as their combination with other therapies.We demonstrate that nMOFs are predominantly customized for vaccine delivery or tumor-microenvironment modulation.Finally,a prospect of nMOFs in cancer immunotherapy will be discussed. | Gaowei Chong Jie Zang Yi Han Runping Su Nopphon Weeranoppanant Haiqing Dong Yongyong Li | 2021 | Nano Research2021，14，5： | 2 |
| 6 | Characterization of modified wheat straw, kinetic and equilibrium study about copper ion and methylene blue adsorption in batch mode 显示文摘 | Runping H Lijun Z Chen S | 2010 | Carbohydrate Polymers2010，79，： | 1 |
| 7 | Temperature stability of symmetric activated carbon supercapacitors assembled with in situ electrodeposited poly (vinyl alcohol) potassium borate hydrogel electrolyte显示文摘The temperature stability of supercapacitor(SC) is largely determined by the properties of the electrolyte.Hydrogel electrolytes(HGE), due to their hydrophilic polymer skeleton, show different temperature stability to that of liquid aqueous electrolytes. In this study, symmetric activated carbon(AC) SCs had been assembled with in situ electrodeposited poly(vinyl alcohol) potassium borate(PVAPB) HGE. The electrochemical performance of the SCs was systematically studied at different temperatures. Results show that the conductivity of PVAPB HGE is comparable with that of liquid aqueous electrolytes at different temperatures. The operating temperature range of PVAPB HGE SCs is -5–60°C, while those of the 1 mol/L Na_2SO_4SCs and the 0.9 mol/L KClSCs are 20–80°C and 20–40°C, respectively. The specific capacitance of PVAPB HGE SC is higher than those of SCs using liquid aqueous electrolytes at any temperature. The excellent temperature stability of PVAPB HGE makes it possible to build stable aqueous SCs in the wider temperature range. | Wanwan Lv Runping Xue Sheng Chen Mengjin Jiang | 2018 | Chinese Chemical Letters2018，29，4： | 1 |
| 8 | A novel pulmonary fibrosis murine model with immune-related liver injury显示文摘Idiopathic pulmonary fibrosis(IPF),characterized by aggravated alveolar destruc-tion and fibrotic matrix deposition,tendentiously experiences the stage called acute exacerbation IPF(AE-IPF)and progresses to multiple organ damage,especially liver injury.Recent studies have found a variety of immune microenvironment disorders associated with elevated IPF risk and secondary organ injury,whereas current animal models induced with bleomycin(BLM)could not completely reflect the pathologi-cal manifestations of AE-IPF patients in clinic,and the exact underlying mechanisms are not yet fully explored.In the current study,we established an AE-IPF model by tracheal administration of a single dose of BLM and then repeated administrations of lipopolysaccharide in mice.This mouse model successfully recapitulated the clinical features of AE-IPF,including excessive intrapulmonary inflammation and fibrosis and extrapulmonary manifestations,as indicated by significant upregulation of Il6,Tnfa,Il1b,Tgfb,fibronectin,and Col1a1 in both lungs and liver and elevated serum aspartate transaminase and alanine transaminase levels.These effects might be attributed to the regulation of Th17 cells.By sharing this novel murine model,we expect to pro-vide an appropriate experimental platform to investigate the pathogenesis of AE-IPF coupled with liver injury and contribute to the discovery and development of targeted interventions. | Kexin Jia Jianzhi Wu Yijie Li Jia Liu Runping Liu Yajie Cai Yinhao Zhang Xiaojiaoyang Li | 2023 | Animal Models and Experimental Medicine2023，6，3： | 1 |
| 9 | Kinetic study of adsorption of Cu(II) and Pb(II) from aqueous solutions using manganese oxide coated zeolite in batch mode显示文摘 | Weihua Zou Runping Han Zongzhang Chen Zhang Jinghua Jie Shi | 2006 | Colloids and Surfaces A: Physicochemical and Engineering Aspects2006，，1： | 1 |
| 10 | Biosorption of copper and lead ions by waste beer yeast 显示文摘 | Han Runping Li Hongkui Li Yanhu | 2006 | J Hazard Mater2006，137，3： | 1 |
| 11 | Study of equilibrium, kinetic and thermodynamic parameters about methylene blue adsorption onto natural zeolite显示文摘 | Han Runping Zhang Jingjing Han Pan | 2009 | Chemical Engineering Journal2009，145，3： | 1 |
| 12 | Biosorption of copper and lead ions by waste beer yeast 显示文摘 | Runping H Hongkui L | 2006 | J Hazard Mater2006，137，： | 1 |
| 13 | Removal of methylene blue from aqueous solution by chaff in batch mode显示文摘 | Runping Han Yuanfeng Wang Pan Han | 2006 | Journal of Hazardous Materials2006，137，： | 1 |
| 14 | Preparation,structural and optical properties of AWO4 (A=Ca,Ba,Sr) nanofilms显示文摘 | ZHANG Guoxin JIA Runping WU Qingsheng | | 0，，123： | 1 |
| 15 | Study of the reaction of proteins with BeryllonⅡ-AlⅢby the Rayleigh light scattering technique and its application显示文摘 | Runping Jia Qianfeng Li | 2001 | Analyst2001，126，： | 1 |
| 16 | Biosorption of copper and lead ions by waste beer yeast显示文摘 | Han Runping Li Hongkui Li Yanhu | 2006 | Journal of Hazardous Materials2006，137，： | 1 |
| 17 | Removal of uranium ( Ⅵ ) from aqueous solutions by manganese oxide coated zeolite:Discussion of adsorption isotherms and pH effect 显示文摘 | Han Runping Zou Weihua Wang Yi | 2007 | Journal of Environmental Radioactivity2007，93，3： | 1 |
| 18 | Hydrogen therapy reduces apoptosis in neonatal hypoxia–ischemia rat model显示文摘 | Jianmei Cai Zhimin Kang Wen Wu Liu Xu Luo Sun Qiang John H. Zhang Shigeo Ohta Xuejun Sun Weigang Xu Hengyi Tao Runping Li | 2008 | Neuroscience Letters2008，，2： | 1 |
| 19 | Adsorption of methylene blue by phoenix tree leaf powder in a fixed-bed column: experiments and prediction of breakthrough curves显示文摘 | Runping Han Yu Wang Xin Zhao Yuanfeng Wang Fuling Xie Junmei Cheng Mingsheng Tang | 2009 | Desalination2009，，1： | 1 |
| 20 | Improved Assimilation of Fengyun-3 Satellite-Based Snow Cover Fraction in Northeastern China显示文摘Assimilation of snow cover is an important method to improve the accuracy of snow simulation. However, the effects of snow assimilation are poor because satellite observed snow cover data contain erroneous information, such as cloud contamination. In this paper, an improved approach is proposed to reduce the effects of observational errors during assimilation of snow cover fraction acquired by the Fengyun-3(FY-3) satellite in northeastern China. A snow depth constraint was imposed on quality control of a snow depth product from a microwave radiation imager. The assimilation experiments were carried out before and after quality control(denoted as SCFDA and SCFDA_WSD, respectively). The snow cover fraction results were evaluated against the Moderate Resolution Imaging Spectroradiometer(MODIS) snow cover products. When assimilating the snow cover fraction with the snow depth constraint(i.e., SCFDA_WSD), substantially larger improvement was obtained than that without such a constraint/quality control(SCFDA), and the deviation and root mean square error of the snow cover fraction were significantly reduced.The assimilation performance was also evaluated against in-situ snow depth observations. The SCFDA_WSD also showed greater improvements during the snow accumulation and snowmelt periods than the SCFDA. The SCFDA_WSD improvements in woodland and shrubland were the most obvious. At different altitudes, the effects of the SCFDA_WSD were basically equivalent, and the deeper the snow depth was, the better the effect. In addition, the SCFDA_WSD method was found in close agreement with the observations during a sudden snowfall event. | Shuai ZHANG Chunxiang SHI Runping SHEN Jie WU | 2019 | Journal of Meteorological Research2019，33，5： | 1 |
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