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| 1 | Kinetics and isotherms of Neutral Red adsorption on peanut husk显示文摘Adsorption of Neutral Red (NR) onto peanut husk in aqueous solutions was investigated at 295 K. Experiments were carried out as function of pH, adsorbent dosage, contact time, and initial concentration. The equilibrium adsorption data were analyzed by Langmuir, Freundlich, Temkin, Dubinin-Radushkevich, and Toth isotherm models. The results indicated that the Toth and Langmuir models provided the best correlation of the experimental data. The adsorption capacity of peanut husk for the removal of NR was determined with the Langmuir and found to be 37.5 mg/g at 295 K. The adsorption kinetic data were modeled using the pseudo-first order, pseudo-second order, and intra-particle diffusion kinetic equations. It was seen that the pseudo-first order and pseudo-second order kinetic equations could describe the adsorption kinetics. The intraparticle diffusion model was also used to express the adsorption process at the two-step stage. It was implied that peanut husk may be suitable as adsorbent material for adsorption of NR from aqueous solutions. | Runping HAN Mingsheng TANG | 2008 | Journal of Environmental Sciences2008，20，9： | 16 |
| 2 | Integrative lipidomic and transcriptomic study unravels the therapeutic effects of saikosaponins A and D on non-alcoholic fatty liver disease显示文摘Nonalcoholic fatty liver disease(NAFLD)has become one of the most prominent causes of chronic liver diseases and malignancies.However,few therapy has been approved.Radix Bupleuri(RB)is the most frequently used herbal medicine for the treatment of liver diseases.In the current study,we aim to systemically evaluate the therapeutic effects of saikosaponin A(SSa)and saikosaponin D(SSd),the major bioactive monomers in RB,against NAFLD and to investigate the underlying mechanisms.Our results demonstrated that both SSa and SSd improved diet-induced NAFLD.Integrative lipidomic and transcriptomic analysis revealed that SSa and SSd modulated glycerolipid metabolism by regulating related genes,like Lipe and Lipg.SSd profoundly suppressed the fatty acid biosynthesis by downregulating Fasn and Acaca expression and promoted fatty acid degradation by inducing Acox1 and Cpt1 a expression.Bioinformatic analysis further predicted the implication of master transcription factors,including peroxisome proliferator-activated receptor alpha(PPARα),in the protective effects of SSa and SSd.These results were further confirmed in vitro in mouse primary hepatocytes.In summary,our study uncoded the complicated mechanisms underlying the promising anti-steatosis activities of saikosaponins(SSs),and provided critical evidence inspiring the discovery of innovative therapies based on SSa and SSd for the treatment of NAFLD and related complications. | Xiaojiaoyang Li Junde Ge Yajing Li Yajie Cai Qi Zheng Nana Huang Yiqing Gu Qi Han Yunqian Li Rong Sun Runping Liu | 2021 | Acta Pharmaceutica Sinica B2021，11，11： | 15 |
| 3 | Bioengineering of nano metal-organic frameworks for cancer immunotherapy显示文摘Immunotherapy techniques,such as immune checkpoint inhibitors,chimeric antigen receptor(CAR)T cell therapies and cancer vaccines,have been burgeoning with great success,particularly for specific cancer types.However,side effects with fatal risks,dysfunction in tumor microenvironment and low immune response rates remain the bottlenecks in immunotherapy.Nano metal-organic frameworks(nMOFs),with an accurate structure and a narrow size distribution,are emerging as a solution to these problems.In addition to their function of temporospatial delivery,a large library of their compositions,together with flexibility in chemical interaction and inherent immune efficacy,offers opportunities for various designs of nMOFs for immunotherapy.In this review,we overview state-of-the-art research on nMOFs-based immunotherapies as well as their combination with other therapies.We demonstrate that nMOFs are predominantly customized for vaccine delivery or tumor-microenvironment modulation.Finally,a prospect of nMOFs in cancer immunotherapy will be discussed. | Gaowei Chong Jie Zang Yi Han Runping Su Nopphon Weeranoppanant Haiqing Dong Yongyong Li | 2021 | Nano Research2021，14，5： | 2 |
| 4 | Kinetic study of adsorption of Cu(II) and Pb(II) from aqueous solutions using manganese oxide coated zeolite in batch mode显示文摘 | Weihua Zou Runping Han Zongzhang Chen Zhang Jinghua Jie Shi | 2006 | Colloids and Surfaces A: Physicochemical and Engineering Aspects2006，，1： | 1 |
| 5 | Biosorption of copper and lead ions by waste beer yeast 显示文摘 | Han Runping Li Hongkui Li Yanhu | 2006 | J Hazard Mater2006，137，3： | 1 |
| 6 | Study of equilibrium, kinetic and thermodynamic parameters about methylene blue adsorption onto natural zeolite显示文摘 | Han Runping Zhang Jingjing Han Pan | 2009 | Chemical Engineering Journal2009，145，3： | 1 |
| 7 | Removal of methylene blue from aqueous solution by chaff in batch mode显示文摘 | Runping Han Yuanfeng Wang Pan Han | 2006 | Journal of Hazardous Materials2006，137，： | 1 |
| 8 | Biosorption of copper and lead ions by waste beer yeast显示文摘 | Han Runping Li Hongkui Li Yanhu | 2006 | Journal of Hazardous Materials2006，137，： | 1 |
| 9 | Removal of uranium ( Ⅵ ) from aqueous solutions by manganese oxide coated zeolite:Discussion of adsorption isotherms and pH effect 显示文摘 | Han Runping Zou Weihua Wang Yi | 2007 | Journal of Environmental Radioactivity2007，93，3： | 1 |
| 10 | Adsorption of methylene blue by phoenix tree leaf powder in a fixed-bed column: experiments and prediction of breakthrough curves显示文摘 | Runping Han Yu Wang Xin Zhao Yuanfeng Wang Fuling Xie Junmei Cheng Mingsheng Tang | 2009 | Desalination2009，，1： | 1 |
| 11 | Characterization of modified wheat straw,kinetic and equilibrium study about copper ion and methylene blue adsorption in batch mode显示文摘 | Han Runping Zhang Lijun Song Chen etal | 2010 | Bioresource Technology2010，79，： | 1 |
| 12 | Comparison of Linear and non-Linear analysis in estimating the Thomas model parameters for methylene blue adsorption onto natural zeolite in fixed-bed column显示文摘 | Han Runping Wang Yi Zou Weihua | 2007 | Journal of Hazardous Materials2007，34，4： | 1 |
| 13 | Biosorption of copper and lead ions by waste beer yeast显示文摘 | Runping Han Hongkui Li Yanhu Li | 2006 | Journal of Hazardous Materials2006，137，3： | 1 |
| 14 | Study of equilibrium kinetic and thermodynamic parameters about methylene blue adsorption onto natural zeolite显示文摘 | Han Runping Zhang Jingjing Han Pan | 2009 | Chemical Engineering Journal2009，145，3： | 1 |
| 15 | Equilibriumbiosorption isothem for lead ion on chaff显示文摘 | HAN Runping ZHANG Jinghua ZOU Weihua | 2005 | Journal of HazardousMaterials2005，125，3： | 1 |
| 16 | Biosorption of copper and lead ions by waste beer yeast 显示文摘 | Runping Han Hongkui Li Yanhu Li | 2006 | Journal of Hazardous Materials2006，137，3： | 1 |
| 17 | Journal of Chemical & Engineering Data 显示文摘 | Wu Yongjun Zhang Lijun Gao Congli Ma Jiangyan Ma Xinghua Han Runping | 2009 | 54(12): 3229-32342009，54，12： | 1 |
| 18 | Removal of uranium (Ⅵ) from aqueous solutions by manganese oxide coated zeolite: discussion of adsorption isotherms and pH effect显示文摘 | Han Runping Zou Weihua Wang Yi | 2007 | J Environ Radioact2007，93，3： | 1 |
| 19 | Copper (Ⅱ ) and lead ( Ⅱ ) removal from aqueous solution in fixed-bed columns by manganese oxide coated zeolite显示文摘 | Han Runping Zou Weihua Li Hongkui | 2006 | J Hazard Mater2006，137，2： | 1 |
| 20 | Biosorption of copper(Ⅱ ) and lead( Ⅱ) from aqueous solution by chaff in a fixed-bed column显示文摘 | Han Runping Zhang Jinghua Zou Weihua | 2006 | J Hazard Mater2006，133，123： | 1 |
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