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| 1 | Penile rehabilitation with a vacuum erectile device in an animal model is related to an antihypoxic mechanism: blood gas evidence显示文摘我们的以前的学习显示出可勃起的设备(VED ) 治疗改进了的那真空在有双边的多孔的神经压碎(BCNC ) 的老鼠的可勃起的功能损害。这研究被设计由分析多孔的氧浸透在阴茎康复探索 VED 的机制(那么 2) 并且在在 BCNC 以后阻止阴茎收缩上检验 VED 治疗的效果。三十只成年 Sprague-Dawley 老鼠随机被分配进三个组:组织 1,假冒的外科;组织 2, BCNC;并且组织 3, BCNC+ VED。阴茎长度和直径在一个每周的基础上被测量。在 4 星期治疗以后,阴茎血被三个方法为血气体分析(BGA ) 提取:方法 1,多孔的血以松驰的状态被把发成送气音;方法 2,多孔的血以拖拉状态被把发成送气音;并且方法 3,多孔的血在使用 VED 以后立即被把发成送气音。2 价值被血气体分析器因此测试。结果证明那 VED 治疗在阻止 BCNC 导致的阴茎收缩是有效的(阴茎弄短:BCNC 组 1.9 ± 1.1 公里;VED 组 0.3 ± 1.0 公里;P< 0.01。阴茎直径减小:BCNC 组 0.28 ± 0.14 公里;VED 组 0.04 ± 0.14 公里;P< 0.01 ) 。2±s.d. 因此珍视的平均数被 VED 申请增加(88.25 % ± 4.94 %) 与相比松驰(76.53 % ± 4.16 %) 或拖拉组(78.93 % ± 2.56 %)(P< 0.05 ) 。在在 VED 申请以后的阴茎海绵体权利的计算的血构造是 62 %动脉并且 38 %静脉的血。这些调查结果建议那 VED 治疗能有效地与 BCNC 损害在老鼠保存阴茎尺寸。VED 治疗的有益的效果与由那么增加多孔的血的 antihypoxia 有关是 2 。 | Hao-Cheng Lin Wen-Li Yang Jun-Lan Zhang Yu-Tian Dai Run Wang | 2013 | Asian Journal of Andrology2013，15，3： | 9 |
| 2 | 内皮祖细胞的动员:糖尿病大鼠长期服用褪黑素预防勃起功能障碍的一个可能机制显示文摘糖尿病引起的氧化应激会对内皮祖细胞从骨髓中的动员产生重要影响。本文旨在探索长期给予褪黑素对提高I型糖尿病大鼠内皮祖细胞的动员作用,以及其对勃起功能障碍的预防功效。链脲佐菌素诱导的I型糖尿病大鼠被给予褪黑素。流式细胞术用于测定内皮祖细胞水平。骨髓组织中超氧化物歧化酶和丙二醛的水平用于反映骨髓组织中氧化应激水平。电刺激勃起神经记录海绵体内压力用于评价大鼠勃起功能。组织学评估阴茎海绵体组织中内皮密度及纤维化程度。结果显示长期给予褪黑素能够提高骨髓组织中超氧化物歧化酶的水平而降低丙二醛的水平,同时提高循环中内皮祖细胞的数量。治疗组大鼠海绵体内压和平均动脉压的比值较糖尿病对照组明显提高。组织学分析显示褪黑素治疗能够提高阴茎海绵体组织中内皮的密度。但是,褪黑素治疗并没有改善糖尿病大鼠阴茎海绵体组织中的纤维化状态。长期给予褪黑素对于保护I型糖尿病大鼠勃起功能具有一定的效果。改善内皮祖细胞的动员是可能的机制之一。 | Xue-Feng Qiu Xiao-Xin Li Yun Chen Hao-Cheng Lin Wen Yu Run Wang Yu-Tian Dai | 2012 | Asian Journal of Andrology2012，14，3： | 5 |
| 3 | Expressions of Nucleoside Diphosphate Kinase (nm23) in Tumor Tissues are Related with Metastasis and Length of Survival of Patients with Hepatocellular Carcinoma显示文摘Objective To evaluate the relationship of expressions of nucleoside diphosphate kinase (nm23) and proliferating cell nuclear antigen (PCNA), as well as apoptosis, with the prognosis of HCC patients by analyzing their pathological and clinical data. Methods The expressions of nm23 and PCNA were analyzed by immunohistochemistry and the apoptotic phenomena were detected by TUNEL technique in the liver samples from 43 HCC tissues, 39 para-neoplastic tissues, and 10 normal tissues. The mean apoptosis index (AI) and proliferative index (PI) in individual sample were calculated. Results As shown by the detection, 32.6% of carcinomas had negative nm23 signal in tumor tissues, whereas all para-neoplastic and normal tissues had positive nm23. The AI in nm23 positive HCC was significantly higher than that in nm23 negative one, with statistical difference (P<0.05). Furthermore, the expressions of nm23, and the values of AI and PI were contrastively analyzed with some main pathological and clinical data of HCC. It revealed that HCC with extrahepatic metastasis showed remarkable correlation with the negative nm23 (P=0.013) and higher PI values of HCC (P=0.015). The disease-free survival in HCC patients with negative nm23 expression was significantly poorer than that in patients with positive nm23 expression. Conclusion These data suggest that expressions of nm23 protein in tumor tissues are correlated with occurrences of metastasis and length of survival of the HCC patients, which may be an indicator for their prognosis. | RUN AN JIE MENG QI SHI XIAO-XIA DAI JING-HONG CHEN YAN-JUN LEI BING SHAN CHEN GAO YONG-LIE CHU XIAO-PING DONG | 2010 | Biomedical and Environmental Sciences2010，23，4： | 4 |
| 4 | The effects of long-term administration of tadalafil on STZ-induced diabetic rats with erectile dysfunction via a local antioxidative mechanism显示文摘类型 5 phosphodiesterase 禁止者(PDE5Is ) 是众所周知的经由氮的氧化物和周期的 guanosine monophosphate (NO-cGMP ) 小径是有效的并且广泛地在糖尿病的可勃起的机能障碍(编辑) 的治疗被使用。然而,另外的小径是否可以与 PDE5Is 涉及糖尿病的编辑的处理,是不清楚的。这研究的目的是通过 PDE5Is 的长期的管理在糖尿病的编辑治疗澄清抗氧化剂的角色。三组 Sprague-Dawley 老鼠被利用:组 N,正常控制;组 D, streptozotocin (STZ ) 作为控制导致了糖尿病的老鼠;并且组织 D+ T,导致 STZ 的糖尿病的老鼠收到了 tadalafil 的口头的管理 8 个星期。可勃起的功能被 intracavernous 压力(ICP ) 和吝啬的动脉的压力(地图) 在无痛苦的死亡前在多孔的神经的电的刺激期间估计。malondialdehyde (MDA ) 的层次, superoxide dismutase (草皮) 和多孔的织物的 mitochondrial 膜潜力(MMP ) 被生物化学的分析估计。线粒体的形态学被电子显微镜学观察。ICP/MAP 比率在组 D+ 是更高的; T 比在组 D (P< 0.05 ) 。MDA 的层次减少了,草皮的活动在组 D+ 增加了;与组 D 比较的 T (P< 0.05 ) 。在糖尿病的老鼠的多孔的组织的 mitochondrial 膜潜力水平被 tadalafil 治疗部分恢复 8 个星期。线粒体的形态学变化显著地也在组 D+ 被改善; T。一起,在糖尿病的老鼠的 tadalafil 的长期的管理部分经由一条本地抗氧化的压力小径减少了阴茎的氧化压力损害。一旦每日的开始,在糖尿病的发作可以帮助阻止老鼠开发糖尿病的编辑后不久,给的 tadalafil 的长期的剂量。 | Yun Chen Xiao-Xin Li Hao-Cheng Lin Xue-Feng Qiu Jing Gao Yu-Tian Dai Run Wang | 2012 | Asian Journal of Andrology2012，14，4： | 4 |
| 5 | Rapid Determination of Silicon Content in Rice显示文摘A method for rapid determination of silicon content in rice was introduced. The reliability of this method was verified byusing a recombinant inbred line (RIL) population of rice cross Zhenshan 97B / Milyang 46. Two hundred and forty-nine RILs weretransplanted in two replications. Simple correlation coefficients on the silicon content in the hull, flag leaf and stem in rice betweenduplicate samples of 498 rice materials were 0.97954, 0.97026 and 0.98848, respectively. Ten representative samples wereselected for measurement using the high-temperature alkaline fusion method. Simple correlation coefficient between the siliconcontents determined by the high-temperature alkaline fusion method and by the present method is 0.9993. | DAI Wei-min ZHANG Ke-qin DUAN Bin-wu SUN Cheng-xiao ZHENG Kang-le CAI Run ZHUANG Jie-yun | 2005 | Rice science2005，12，2： | 4 |
| 6 | Prospective and long-term evaluation of erect penile length obtained with inflatable penile prosthesis to that induced by intracavernosal injection显示文摘在有那的可膨胀的阴茎修复术(IPP ) 培植在外科前由 in-tracavernosal 注射(帝国化学工业公司) 导致了以后,我们比较了直立的阴茎长度。有充分勃起的 11 个病人的一个总数在阴茎颜色的时候由 Trimix (papaverine, phentolamine 和前列腺素 E1 ) 的 0.25 mL 的帝国化学工业公司导致了双 Doppler ultrasonography 在这研究被注册。病人随后为他们的可勃起的机能障碍(编辑) 作为最终的治疗经历了 IPP 培植。对 IPP 培植作为结果的直立的阴茎长度在 6 个星期被测量, 6 个月并且在在外科以后的 1 年。为男人(填隙用木片) 的性健康库存在 IPP 培植以后被管理在前,并且在 6 个月和 1 年。是导致了由树立阴茎长度(吝啬的 s.e ) 而与 IPP 达到的长度是 12.4,帝国化学工业公司是 13.2 0.4 厘米 0.3,在第六个星期,第六个月和 1 年的后续的 12.5 0.3 和 12.5 0.4 厘米分别地。有 0.83 0.25,分别地, 0.75 0.20 和 0.74 0.15 厘米在 IPP 培植以后在 6 个星期, 6 个月和 1 年在直立的阴茎长度减少什么时候与那相比在帝国化学工业公司以后(P < 0.05 ) 。没有抱怨,为报导更短的阴茎的病人的填隙用木片分数与为病人的那些一样(P > 0.05 ) 。到我们的知识,这是第一研究客观地在 IPP 培植以后在直立的阴茎长度看重要减少是否与那相比在帝国化学工业公司以后。然而,这减少没在对待编辑影响 IPP 的有效性。 | Run Wang Galen E Howard Anthony Hoang Jiu-Hong Yuan Hao-Cheng Lin Yu-Tian Dai | 2009 | Asian Journal of Andrology2009，11，4： | 3 |
| 7 | Over-expression of nm23-H1 in HeLa cells provides cells with higher resistance to oxidative stress possibly due to raising intracellular p53 and GPX显示文摘瞄准:决定反肿瘤因素 nm23 是否与反氧化是相关的。方法:全身的人的 nm23-H1 被克隆进哺乳动物表示的向量并且短暂地介绍了房间进 HeLa。结果:反应的氧种类(ROS ) 显著地低级的 A 在细胞被检测过去表示的 nm23-H1。3-(4,5-Dimethylthiazol-2-yl )-2,5-diphenyltetrazolium 溴化物和尝试平底锅蓝色试金发现有一个 nm23-H1-expressing 原生质标志的房间 transfected 有更高的生存能力和更强壮的抵抗到氧化应力。Immunoprecipitation 测试表明内长的 nm23-H1 与 p53 形成了蛋白质建筑群。而且, p53 的细胞内部的层次和 p53-regulatedgene GPX1 显然在表示 nm23-H1 上在房间被增加。下面在在表示 nm23-H1 上的房间的 p53 的规定导致了更高细胞的 ROS 水平和更低的房间生存能力。结论:调查结果建议 nm23-H1 可以对氧化应力充当一个细胞的保护者,可能触发 p53 相关的抗氧化的小径。 | Run AN Yong-lie CHU Chan TIAN Xiao-xia DAI Jing-hong CHEN Qi SHI Jun HAN Xiao-ping DONG | 2008 | Acta Pharmacologica Sinica2008，29，12： | 2 |
| 8 | Effect of boron on the superconducting transition of heavily doped diamond显示文摘 | Dai Ying Long Run Huang Baibiao | 2007 | Diamond Related Mater2007，16，2： | 1 |
| 9 | A Preliminary Urinary Metabolomics Study of Sprague-Dawley Rats after Short‑term Ketamine Administration by Proton Nuclear Magnetic Resonance Spectroscopy显示文摘Drug abuse has become a global problem.The mass spectrometry‑based metabolic consequences of ketamine administration in anesthesia and therapy have been well studied,but to the best of our knowledge,metabolomic studies of ketamine abuse based on nuclear magnetic resonance(NMR)spectroscopy are still lacking.In this study,twenty Sprague–Dawley rats were randomly assigned into two groups:a control group(n=10)and a ketamine group(n=10).The animals in the ketamine group received intraperitoneal injections of ketamine twice daily at 12‑h intervals at progressively increasing doses over a period of 9 days,while the control group received an equal volume of saline.The urine samples were collected for 24 h at days 0,1,3,5,7,and 9 for the metabolomics study.The metabolic changes in urine after short‑term ketamine administration were analyzed by proton NMR coupled with multivariate statistical analysis.The results indicated that short‑term ketamine exposure led to significant alterations of the metabolites in the urine of the rats.Specifically,1,3,7‑trimethyluric acid,1,3‑dimethyluric acid,acetoacetic acid,acetylglycine,creatine,sarcosine,dimethylglycine,glycine,and theobromine were significantly increased in the urine.Significant changes were also found in metabolites related to antioxidant and energy metabolism,including acetoacetic acid,succinate,1,3,7‑trimethyluric acid,1,3‑dimethyluric acid,creatine,and taurine.Our findings indicated that short‑term ketamine administration leads to disorder of energy metabolism and oxidative stress.In addition,the modified metabolites identified could serve as the new biological markers and potential biological indices reflecting the underlying mechanism of ketamine abuse. | Xiang Lu Qunxing Tang Yi Ye Run Guo Fan Chen Xinhua Dai Youyi Yan Linchuan Liao | 2016 | Journal of Forensic Science and Medicine2016，2，2： | 1 |
| 10 | Structural and electronic properties of iodine-doped anatase and rutile TiO 2显示文摘 | Run Long Ying Dai Baibiao Huang | 2008 | Computational Materials Science2008，，2： | 1 |
| 11 | Advances in nuclear detection and readout techniques显示文摘“A Craftsman Must Sharpen His Tools to Do His Job,”said Confucius.Nuclear detection and readout techniques are the foundation of particle physics,nuclear physics,and particle astrophysics to reveal the nature of the universe.Also,they are being increasingly used in other disciplines like nuclear power generation,life sciences,environmental sciences,medical sciences,etc.The article reviews the short history,recent development,and trend of nuclear detection and readout techniques,covering Semiconductor Detector,Gaseous Detector,Scintillation Detector,Cherenkov Detector,Transition Radiation Detector,and Readout Techniques.By explaining the principle and using examples,we hope to help the interested reader underst and this research field and bring exciting information to the community. | Rui He Xiao‑Yang Niu Yi Wang Hong‑Wei Liang Hong‑Bang Liu Ye Tian Hong‑Lin Zhang Chao‑Jie Zou Zhi‑Yi Liu Yun‑Long Zhang Hai‑Bo Yang Ju Huang Hong‑Kai Wang Wei‑Jia Han Bei Cao Gang Chen Cong Dai Li‑Min Duan Rui‑Rui Fan Fang‑Fa Fu Jian‑Hua Guo Dong Han Wei Jiang Xian‑Qin Li Xin Li Zhuo‑Dai Li Yu‑Tie Liang Shun Liao De‑Xu Lin Cheng‑Ming Liu Guo‑Rui Liu Jun‑Tao Liu Ze Long Meng‑Chen Niu Hao Qiu Hu Ran Xiang‑Ming Sun Bo‑Tan Wang Jia Wang Jin‑Xiang Wang Qi‑Lin Wang Yong‑Sheng Wang Xiao‑Chuan Xia Hao‑Qing Xie He‑Run Yang Hong Yin Hong Yuan Chun‑Hui Zhang Rui‑Guang Zhao Ran Zheng Cheng‑Xin Zhao | 2023 | Nuclear Science and Techniques2023，34，12： | 0 |
| 12 | Sharp recanalization using Chiba biopsy needle for the treatment of biliary occlusion after radiofrequency ablation显示文摘Introduction Biliary stricture is a less common complication after hepatic radiofrequency ablation(RFA)[1,2].Patients with biliary stricture often present with recurrent jaundice,fever or chills,and require endoscopic or percutaneous biliary drainage,and in some cases recanalization of the biliary tract[3].Establishing guide-wire passage through the stricture is essential for biliary recanalization.However,in some cases of complete biliary obstruction,a more aggressive technique is needed when ordinarymethods fail to establish.Herein,we report a novel technique of extraluminal recanalization for biliary strictures using a Chiba biopsy needle,which is similar to sharp endovascular recanalization. | Bin Chen Haitao Dai Keyu Tang Run Lin Yonghui Huang | 2022 | Gastroenterology Report2022，10，1： | 0 |
| 13 | Ultrafast Phenomena in Solids Excited by Femtosecond Pulse显示文摘The pump-probe technique is an effective instrument for investigating ultrafast dynamics. It is widely used in fundamental research and application fields, such as Physics, Chemistry and Biology. First introduced is the effect process between femtosecond laser and matter. And set forth is the fundamental of ultrafast phenomena and theory foundation of data disposal. Then introduced is the demand of making samples in experiment, experiment equipment, and the theory of strain pulse. We detect transient reflectivity change on surface of GaAs at different delayed time using femtosecond transient reflection spectroscopy. The changing curve consists of three parts: original scattering process of 100 fs, carriers-lattice thermal equilibrium of 1.5 ps and recombination process of 500 ps. | YUAN Dong-qing ZHOU Ming DAI Qi-xun YUAN Run LIU Hui-xia REN Nai-fei CHEN Lei | 2007 | Semiconductor Photonics and Technology2007，13，4： | 0 |
| 14 | Yiqi Qingre Xiaozheng formula protects against diabetic nephropathy by restoring autophagy in mice显示文摘Objective:To evaluate the protective effect of Yiqi Qingre Xiaozheng formula(YQQRXZF)via the regulation of autophagy in diabetic nephropathy(DN)mice induced by injection of streptozotocin(STZ)after high fat diet(HFD).Methods:The composition of YQQRXZF was analyzed by high performance liquid chromatographyelectrospray ionization/mass spectrometry(HPLC-ESI/MSn).The DN model was induced by intraperitoneally injection of 50 mg/kg STZ within 5 days,followed by HFD feeding for 8 weeks in C57BL/6J mice.Mice were randomly separated into DN group,YQQRXZF group,irbesartan group,and control group.Blood glucose was calculated,and body weight was measured every 2 weeks.An enzyme-linked immunosorbent assay was used to measure the urinary albumin-to-creatinine ratio(uACR)before and after treatment,and the serum concentrations of total cholesterol(TC),low-density lipoprotein(LDL),triglycerides(TG),high-density lipoprotein(HDL),blood urea nitrogen(BUN),and serum creatinine(Scr)were measured.In addition,hematoxylin-eosin(H&E)staining,periodic acid-Schiff(PAS)staining,Masson's trichrome staining,and transmission electron microscopy(TEM)were used to observe pathological changes in renal tissue.Autophagy levels were determined by immunofluorescence staining.Results:In this study,21 dominant chemical constituents were identified in YQQRXZF.The treatment group reduced u ACR in a more significant way than the DN group(P=.018).The treatment group reduced TC,TG,and LDL concentrations after YQQRXFF treatment(P=.021,P=.014 and P=.026,respectively).H&E,PAS,and Masson staining showed that pathological damage to mice kidneys improved,the volume of renal glomeruli was reduced,and glomerular sclerosis and fibrosis were reduced.Immunofluorescence analysis revealed that expressions of LC3-Ⅱprotein increased in the treatment group(P=.013).In contrast,the protein expressions of P62 were reduced after treatment(P=.025). | Na Sun Nan Yang Jingwei Zhou Ying He Jian Wang Yingnan Liang Run Dai Jiajia Bai Zhenjie Chen | 2023 | Journal of Traditional Chinese Medical Sciences2023，10，3： | 0 |
| 15 | Mn-doping induced electronic modulation and rich oxygen vacancies on vertically grown NiFe2O4 nanosheet array for synergistically triggering oxygen evolution reaction显示文摘Large-scale electrolysis of water to produce high-purity hydrogen is one of the effective ways to solve the energy crisis and environmental pollution problems.However,efficient,cheap and stable catalysts are one of the bottlenecks for industrial application in water splitting.Herein,a facile one-step hydrothermal process was applied to fabricate Mn-doped nickel ferrite nanosheets(Mn-NiFe_(2)O_(4))which shown a low overpotential of 200 mV at 50 mA·cm^(-2)and a small Tafel slope of 47 mV·dec^(-1),together with a prominent turnover frequency(TOF)value(0.14 s^(-1))and robust stability.The in-situ UV-vis spectroscopy unveiled the surface reconstruction to generate NiOOH as active sites during oxygen evolution reaction(OER).The excellent electrocatalytic activity of Mn-NiFe_(2)O_(4)is attributed to the vertically grown nanosheets for exposure more active sites,rich oxygen vacancies,and the hybridization between Ni 3d and O 2p orbitals caused by Mn doping.This work should provide a facile strategy by Mn-doping to simultaneously engineer oxygen vacancies and electronic structure for synergistically triggering oxygen evolution reaction. | Yonghao Gan Meilin Cui Xiaoping Dai Ying Ye Fei Nie Ziteng Ren Xueli Yin Baoqiang Wu Yihua Cao Run Cai Xin Zhang | 2022 | Nano Research2022，15，5： | 0 |
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