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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Oxidative environments decrease tenderization of beef steaks through inactivation of μ-ealpain显示文摘 | Rowe L J Maddock K P Lonergan S M | 2004 | J Anita Sci2004，82，： | 1 |
| 3 | High-temperature refractory metal-intermetallic composites显示文摘 | BEWLAY B P ROWE R G | 1996 | JOM1996，1996，： | 1 |
| 4 | High temperature refractory metal intermetallic composites 显示文摘 | JACKSON M R BEWLAY B P ROWE R G | 1996 | JOM1996，48，： | 1 |
| 5 | Optimism, coping, and long-term recovery from coronary artery surgery in women显示文摘 | King K B Rowe M A Kimble L P | 1998 | Res Nuts Health1998，21，1： | 1 |
| 6 | Epidemic Escherichia coli O157:H7 gastrocnteritis and hemolytic-uremic syndrome in a Canadian Inuit community: intestinal illness in family members as a risk factor显示文摘 | ROWE P C ORRBINE E OGBOM M | 1994 | J Pediatr1994，124，： | 1 |
| 7 | Molecular cloning of polyoma virus DNA in Escherichia coli: plasmid vector system显示文摘 | Israel M A Chan H W Rowe W P | 1979 | Science1979，203，4383： | 1 |
| 8 | High-temperature refractory metal-intermetallic composites显示文摘 | JACKSON M R BEWLAY B P ROWE R G SKELLY D W LIPSITT H A | 1996 | JOM1996，48，1： | 1 |
| 9 | Hightemperature refractory metal-intermetallic composites显示文摘 | BEWLAY B P ROWE R G | 1996 | JOM1996，48，1： | 1 |
| 10 | Intrauterine devices and pelvic inflammatory disease: an international perspective 显示文摘 | Farley T M Rosenberg M J Rowe P | 1992 | Lancet1992，339，8796： | 1 |
| 11 | Serum 2-hydroxyglutarate levels predict isocitrate dehydrogenase mutations and clinical outcome in acute myeloid leukemia显示文摘 | DiNardo C D Propert K J Loren A W Paietta E Sun Z X Levine R L Straley K S Yen K Patel J P Agresta S Abdel-Wahab O Perl A E Litzow M R Rowe J M Lazarus H M Fernandez H F Margolis D J Tallman M S Luger S M Carroll M | 2012 | Blood2012，121，24： | 1 |
| 12 | Molecular cloning of polyoma virus DNA in Escherichia coli:plasmid vector system显示文摘 | Israel M A Chan H W Rowe W P | 1997 | Science1997，203，4383： | 1 |
| 13 | Collagen biomechanics in cerebral arteries and bifurcations assessed by polarizing microscopy显示文摘 | Rowe A J Finlay H M Canham P B | 2003 | J Vasc Res2003，40，4： | 1 |
| 14 | A distinct lineage of influenza A virus from bats显示文摘 | Tong S Li Y Rivailler P Conrardy C Castillo D A Chen L M Recuenco S Ellison J A Davis C T York I A Turmelle A S Moran D Rogers S Shi M Tao Y Weil M R Tang K Rowe L A Sammons S Xu X Frace M Lindblade K A Cox N J Anderson L J Rupprecht C E Donis R O | 2012 | PANS2012，109，11： | 1 |
| 15 | Voltage - gated sodi- um channel in grasshopper mice defends against bark scor- pion toxin显示文摘 | Rowe A H Xiao Y Rowe M P | 2013 | Science2013，342，： | 1 |
| 16 | Phylogenetic relationships within the cyst-forming nematodes (Nem toda:Heteroderidae) based on analysis of sequences from the ITS regions of ribosomal DNA显示文摘 | SUBBOTIN S A VIERSTRAETE A DE LEY P ROWE J WAEYENBERGE L MOENS M & VANFLETEREN J R | | 0，，： | 1 |
| 17 | 查看详情显示文摘 | Herle P S Hegde M S Sooryanarayana K Guru Row T N Subbanna G N | | 0，，： | 1 |
| 18 | Effect of supplemental trace-mineral source on bull semen quality显示文摘 | Rowe M P Powell J G Kegley E B Lester T D Rorie R W | 2014 | Professional Animal Scientist2014，，1： | 1 |
| 19 | A Personality-Based Similar-To-Me Effect in the Employment Interview: Conscientiousness, Affect- Versus Competence-Mediated Interpretations, and the Role of Job Relevance 显示文摘 | Sears G J & Rowe P M | 2003 | Canadian Journal of Behavioral Science2003，35，1： | 1 |
| 20 | Evaluation of Aspects of E^* Test Using Hotmix-Asphalt Specimens with Varying Void Contents显示文摘 | ROWE G M HAKIMZADEH S BLANKENSHIP P | 2009 | Transportation Research Record2009，，2127： | 1 |
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