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| 1 | 三相并网逆变器比例谐振控制及其网压前馈问题分析显示文摘静止坐标系下的比例谐振控制因其具有对特定频率响应速度快、不存在耦合项并易实现谐波补偿这三个显著特点得到了广泛的关注,并被应用于多种分布式发电系统当中。本文对静止坐标系下的比例谐振控制进行了说明与分析,同时针对比例谐振控制的特点,提出了一种带有比例系数的正序网压前馈控制方法。该方法通过引入正序网压前馈环节,相比传统的比例谐振控制方法进一步提高了系统的动态响应能力,在逆变器公用接入点(PCC)电压畸变的情况下,正序网压前馈环节降低了网压畸变对并网电流造成的负面影响,并得到了实验的验证。 | 马琳 金新民 唐芬 Pedro Rodriguez 孙凯 | 2012 | 电工技术学报2012，27，8： | 63 |
| 2 | Aggressive blood pressure treatment of hypertensive intracerebral hemorrhage may lead to global cerebral hypoperfusion:Case report and imaging perspective显示文摘Hypoperfusion injury related to blood pressure decrease in acute hypertensive intracerebral hemorrhage continues to be a controversial topic. Aggressive treatment is provided with the intent to stop the ongoing bleeding. However, there may be additional factors, including autoregulation and increased intracranial pressure, that may limit this approach. We present here a case of acute hypertensive intracerebral hemorrhage, in which aggressive blood pressure management to levels within the normal range led to global cerebral ischemia within multiple border zones. Global cerebral ischemia may be of concern in the management of hypertensive hemorrhage in the presence of premorbid poorly controlled blood pressure and increased intracranial pressure. | Jose Gavito-Higuera Rakesh Khatri Ihtesham A Qureshi Alberto Maud Gustavo J Rodriguez | 2017 | World Journal of Radiology2017，9，12： | 49 |
| 3 | 探索MOOC教学方法在mLearning中的运用显示文摘本文把大型开放式网络课程(Massively Open Online Course,以下简称MOOC)作为适应移动学习(mLearning)的一种可能的教学方法,这种教学方法建立在与当前学习或教学形式相适宜的基础上。本文呈现了一个MobiMOOC应用的案例研究,该案例使用MOOC形式创建一门课程,研究展示了MOOC和mLearning之间的协同特性,并将当前数字化的协作学习和知识建构这两个理想领域结合在一起。MobiMOOC是聚焦于mlearning、为期六周的网上课程,于2011年的4月到5月之间进行。MobiMOOC是免费开放的课程,有556位学习者加入了课程谷歌群组。课程结束时的调查结果有力地证明了MOOCs和mLearning之间的协同作用。本篇论文对时间和地点的独立性、情境学习、协作学习、潜在的跨学科信息交流,以及应用于网上学习的技术,如社交媒体,移动设备等方面进行了探讨。 | Inge DE Waard Apostolos Koutropoulos Nilgün zdamar Keskin Sean C.Abajian Rebecca Hogue C.Osvaldo Rodriguez Michael Sean Gallagher 何伏刚 马东明 孙海民 | 2012 | 中国远程教育2012，，5： | 39 |
| 4 | Endoscopic management of esophageal varices显示文摘The rupture of gastric varices results in variceal hemorrhage, which is one the most lethal complications of cirrhosis. Endoscopic therapies for varices aim to reduce variceal wall tension by obliteration of the varix. The two principal methods available for esophageal varices are endoscopic sclerotherapy (EST) and band ligation (EBL). The advantages of EST are that it is cheap and easy to use, and the injection catheter fits through the working channel of a diagnostic gastroscope. Endoscopic variceal ligation obliterates varices by causing mechanical strangulation with rubber bands. The following review aims to describe the utility of EBL and EST in different situations, such as acute bleeding, primary and secondary | Joaquin Poza Cordon Consuelo Froilan Torres Aurora Burgos García Francisco Gea Rodriguez Jose Manuel Suárez de Parga | 2012 | World Journal of Gastrointestinal Endoscopy2012，4，7： | 27 |
| 5 | Repression of Cell Proliferation by miR319-Regulated TCP4显示文摘叶开发广泛地在基因水平上被学习了。然而,很少对在 thedevelopmental 管理者和最终影响叶形式和尺寸的细胞周期 machinerya 连接之间的相互影响被知道。miR319 是调整涉及多重发展小径的 TCP 抄写因素的 conservedmicroRNA,包括叶 developmentand 老朽,机关弯曲,和荷尔蒙生合成并且发信号。这里,我们在房间增长的 thecontrol 分析 TCP4 的参予。TCP4 活动的小增加在叶细胞数字上有立即的影响,由 significantlyreducing 细胞增长。有高 TCP4 层次的植物在知道是房间周期的 activein G2-M 阶段的基因的表示有强壮的减小。这些效果的部分被 miR396 的正式就职调停,它镇压 Growth-RegulatingFactor (GRF ) 抄写因素。详细分析揭示了 TCP4 是 MIR396b 的一个直接管理者。然而,我们发现 TCP4 能通过另外的小径控制房间增长,并且我们识别了直接 connectionbetween TCP4 和 ICK1/KRP1,涉及房间周期的前进的基因。我们的结果证明 TCP4 能激活不同小径那 represscell 增长。 | Carla Schommer Juan M. Debernardi Edgardo G. Bresso Ramiro E. Rodriguez Javier F. Palatnik | 2014 | Molecular Plant2014，7，10： | 25 |
| 6 | Machine learning modeling of superconducting critical temperature显示文摘Superconductivity has been the focus of enormous research effort since its discovery more than a century ago.Yet,some features of this unique phenomenon remain poorly understood;prime among these is the connection between superconductivity and chemical/structural properties of materials.To bridge the gap,several machine learning schemes are developed herein to model the critical temperatures(T_(c))of the 12,000+known superconductors available via the SuperCon database.Materials are first divided into two classes based on their T_(c) values,above and below 10 K,and a classification model predicting this label is trained.The model uses coarse-grained features based only on the chemical compositions.It shows strong predictive power,with out-of-sample accuracy of about 92%.Separate regression models are developed to predict the values of T_(c) for cuprate,iron-based,and low-T_(c) compounds.These models also demonstrate good performance,with learned predictors offering potential insights into the mechanisms behind superconductivity in different families of materials.To improve the accuracy and interpretability of these models,new features are incorporated using materials data from the AFLOW Online Repositories.Finally,the classification and regression models are combined into a single-integrated pipeline and employed to search the entire Inorganic Crystallographic Structure Database(ICSD)for potential new superconductors.We identify>30 non-cuprate and non-iron-based oxides as candidate materials. | Valentin Stanev Corey Oses A.Gilad Kusne Efrain Rodriguez Johnpierre Paglione Stefano Curtarolo Ichiro Takeuchi | 2018 | npj Computational Materials2018，，1： | 21 |
| 7 | ESCRT-I Component VPS23A Affects ABA Signaling by Recognizing ABA Receptors for Endosomal Degradation显示文摘受体在过去的十年在植物科学成为了很重要的进展之一的 PYR/PYL/RCAR-type abscisic 酸(骆驼毛的织物) 的最近的发现。在哺乳动物,排序的 endosomal 充当一条重要小径到 downregulate 受体的不同类型,而是它在植物荷尔蒙发信号的角色糟糕被理解。这里,我们报导那 ubiquitin 象 E2 一样蛋白质, VPS23A,是 ESCRT-I 的一个关键部件,否定地调整骆驼毛的织物发信号。VPS23A 与 PYR/PYL/RCAR-type 骆驼毛的织物受体和提高的 VPS23A 的混乱有 epistatic 关系在在骆驼毛的织物处理下面表明小径的 ABA 的关键 kinase OST1 的活动。而且, VPS23A 与 PYR1/PYLs 交往,连接 K63 的 diubiquitin,和 PYL4 在 vivo 拥有连接 K63 的 ubiquitinated 修正。进一步的分析表明 VPS23A 影响 PYR1 和 PYL4 的稳定性的 subcellular 本地化。一起拿,我们的结果建议 VPS23A 经由调停液泡的降级影响 PYR1/PYL4,提供两个的先进理解在植物荷尔蒙发信号的骆驼毛的织物受体和 ESCRT 的周转。 | Feifei Yu Lijuan Lou Miaomiao Tian Qingliang Li Yanglin Ding Xiaoqiang Cao Yaorong Wu Borja Belda-Palazon Pedro L. Rodriguez Shuhua Yang Qi Xie | 2016 | Molecular Plant2016，9，12： | 17 |
| 8 | Atomic-layered Au clusters on α-MoC as catalysts for the low-temperature water-gas shift reaction显示文摘Subject Code:B03With the support by the National Natural Science Foundation of China,a collaborative study by the research groups led by Prof.Ma Ding(马丁)from Peking University,Senior Scientist JoséA.Rodriguez from Brookhaven National Laboratory and Prof.Shi Chuan(石川)from Dalian University of | Ma Ding (马丁) José A. Rodriguez Shi Chuan (石川) | 2017 | Science Foundation in China2017，25，3： | 16 |
| 9 | DNA and histone methylation in gastric carcinogenesis显示文摘Epigenetic alterations contribute significantly to the development and progression of gastric cancer,one of the leading causes of cancer death worldwide.Epigenetics refers to the number of modifications of the chromatin structure that affect gene expression without altering the primary sequence of DNA,and these changes lead to transcriptional activation or silencing of the gene.Over the years,the study of epigenetic processes has increased,and novel therapeutic approaches that target DNA methylation and histone modifications have emerged.A greater understanding of epigenetics and the therapeutic potential of manipulating these processes is necessary for gastric cancer treatment.Here,we review recent research on the effects of aberrant DNA and histone methylation on the onset and progression of gastric tumors and the development of compounds that target enzymes that regulate the epigenome. | Danielle Queiroz Calcagno Carolina Oliveira Gigek Elizabeth Suchi Chen Rommel Rodriguez Burbano Marília de Arruda Cardoso Smith | 2013 | World Journal of Gastroenterology2013，19，8： | 14 |
| 10 | Effect of two different extracts of red maca in male rats with testosterone-induced prostatic hyperplasia显示文摘瞄准:在更男的 ats 决定红 maca 的二篇不同摘录的效果。方法:Prostatic 增生与睾丸激素 enanthate (TE ) 在雄的老鼠被导致。Thestudy 包括了六个组:一个控制组(组 1 ),与 TE (组 2 )对待的一个组,与 TE 对待的二个组和红 maca 的水的摘录(组织 3 和 4 ),一个组对待红 maca (组 5 )的 withhydroalcoholic 摘录,一个组与 finasteride 对待( 0.1 mg , group6 )。在沸腾的时间的长度上的水的摘录依赖者的差别,是否为 2 个 or3 小时,为组, 3 和 4 被估计。红 maca 的摘录包含了 0.1 mg ofbenzylglucosinolate。此后,在红 maca 摘录的 benzylglucosinolates (0.02-0.08 mg ) 的不同剂量的剂量反应效果被估计。结果:前列腺重量在与红 maca 的水的摘录在沸腾的 2 和 3 个小时以后准备了的 freeze-dried 对待的老鼠是类似的。红 maca 的 Freeze-dried 水的摘录,红 maca 和 finasteride 的水疗院酒鬼摘录与职业人员静电干扰增生在老鼠减少了前列腺重量。没有差别在从水的摘录或红 maca 的水疗院酒鬼摘录获得的数据之间被观察。前列腺重量的剂量依赖者减小随红 macaextracts 的 benzylglucosinolates 的剂量的增加被观察。结论:现在的学习在 prostatichyperplasia 被 TE 在导致了的雄的老鼠给那个水疗院酒鬼或红 macacontaining 的水的摘录看了 benzylglucosinolate 罐头还原剂前列腺尺寸的 0.1 mg。 | Gustavo F. Gonzales Vanessa Vasquez Daniella Rodriguez Carmen Maldonado Juliet Mormontoy Jimmy Portella Monica Pajuelo León Villegas Manuel Gasco | 2007 | Asian Journal of Andrology2007，9，2： | 14 |
| 11 | A Direct Link between Abscisic Acid Sensing and the Chromatin-Remodeling ATPase BRAHMA via Core ABA Signaling Pathway ComDonents显示文摘对干旱的最佳的反应为植物幸存是批评的并且将在气候变化期间影响生物多样性和庄稼性能。有丝分裂地可继承的 epigenetic 或动态染色质状态变化在对干旱压力荷尔蒙 abscisic 酸(骆驼毛的织物) 的植物反应被含有。Arabidopsis SWI/SNF 改变染色质的 ATPase 梵天(BRM ) 由在萌芽期间阻止压力反应小径的早熟的激活调制反应到骆驼毛的织物。我们证明核心骆驼毛的织物发信号小径部件身体上与 BRM 交往并且 post-translationally 由 phosphorylation/dephosphorylation 修改 BRM。基因证据建议 SnRK2.2/2.3 kinases 下游的 BRM 行为,和生物化学的研究鉴别在在 SnRK2 的 BRM 的 C 终端区域的 phosphorylation 地点指向 evolutionarily 被保存的地点。最后, phosphomimetic BRM S1760D S1762D 异种显示骆驼毛的织物超敏性。优先的研究证明 BRM 当面在 ABA 小径住在目标 loci 并且刺激的缺席,但是当骆驼毛的织物不在时仅仅是活跃的。我们的数据建议 BRM 的 SnRK2 依赖的 phosphorylation 导致它的抑制,并且 BRM 的调停 PP2CA 的 dephosphorylation 恢复 BRM 的能力镇压骆驼毛的织物反应。这些调查结果点到存在一快速基于 phosphorylation 换到控制 BRM 活动;这个性质能潜在地被利用在植物改进干旱忍耐。 | Marta Peirats-Llobet Soon-Ki Han Miguel Gonzalez-Guzman Cheol Woong Jeong Lesia Rodriguez Borja Belda-Palazon Doris Wagner Pedro L. Rodriguez | 2016 | Molecular Plant2016，9，1： | 13 |
| 12 | Liver expression of steroid hormones and Apolipoprotein D receptors in hepatocellular carcinoma显示文摘AIM: To evaluate the tissular expression of Androgen (A), Estrogen (E) and Progesterone (Pg) receptors, and Apolipoprotein D (ApoD), in liver tumors from resected hepatocellular carcinoma (HCC) cases in order to assess their possible relationship to prognosis. METHODS: We performed an immunohistochemical study using tissue microarrays (containing more than 260 cancer specimens, from 31 HCC patients and controls) to determine the presence of specif ic antibodies against AR, ER, PgR and ApoD, correlating their findings with several clinico-pathological and biological variables. The staining results were categorized using a semi-quantitive score based on their intensity, and the percentage of immunostained cells was measured. RESULTS: A total of 21 liver tumors (67.7%) were positive for AR; 16 (51.6%) for ER; 26 (83.9%) for PgR and 12 (38.7%) stained for ApoD. We have found a wide variability in the immunostaining score values for each protein, with a median (range) of 11.5 (11.5-229.5) for AR; 11.1 (8.5-65) for ER; 14.2 (4-61) for PgR; and 37.7 (13.8-81.1) for ApoD. A history of heavy ethanol consumption, correlated positively with AR and PgR and negatively with ER status. HCV chronic infection also correlated positively with AR and PgR status. However, the presence of ApoD immunostaining did not correlate with any of these variables. Tumors with a positive immuno-staining for PgR showed a better prognosis. CONCLUSION: Our results indicate a moderate clinical value of the steroid receptor status in HCC, emphasizing the need to perform further studies in order to evaluate the possible role of new hormonal-based therapies. | FJ Vizoso M Rodriguez A Altadill ML González-Diéguez A Linares LO González S Junquera F Fresno-Forcelledo MD Corte L Rodrigo | 2007 | World Journal of Gastroenterology2007，13，23： | 11 |
| 13 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 14 | Role of mi RNAs and their potential to be useful as diagnostic and prognostic biomarkers in gastric cancer显示文摘Alterations in epigenetic control of gene expression play an important role in many diseases, including gastric cancer. Many studies have identified a large number of upregulated oncogenic mi RNAs and downregulated tumour-suppressor mi RNAs in this type of cancer. In this review, we provide an overview of the role of mi RNAs, pointing to their potential to be useful as diagnostic and/or prognostic biomarkers in gastric cancer. Moreover, we discuss the influence of polymorphisms and epigenetic modifications on mi RNA activity. | Kelly Cristina da Silva Oliveira Taíssa Maíra Thomaz Araújo Camila Inagaki Albuquerque Gabriela Alcantara Barata Carolina Oliveira Gigek Mariana Ferreira Leal Fernanda Wisnieski Fernando Augusto Rodrigues Mello Junior André Salim Khayat Paulo Pimentel de Assumpcao Rommel Mário Rodriguez Burbano Marília Cardoso Smith Danielle Queiroz Calcagno | 2016 | World Journal of Gastroenterology2016，22，35： | 11 |
| 15 | Role of apoptosis-inducing factor in perinatal hypoxic-ischemic brain injury显示文摘Perinatal complications,such as asphyxia,can cause brain injuries that are often associated with subsequent neurological deficits,such as cerebral palsy or mental retardation.The mechanisms of perinatal brain injury are not fully understood,but mitochondria play a prominent role not only due to their central function in metabolism but also because many proteins with apoptosis-related functions are located in the mitochondrion.Among these proteins,apoptosis-inducing factor has already been shown to be an important factor involved in neuronal cell death upon hypoxia-ischemia,but a better understanding of the mechanisms behind these processes is required for the development of more effective treatments during the early stages of perinatal brain injury.In this review,we focus on the molecular mechanisms of hypoxic-ischemic encephalopathy,specifically on the importance of apoptosis-inducing factor.The relevance of apoptosis-inducing factor is based not only because it participates in the caspase-independent apoptotic pathway but also because it plays a crucial role in mitochondrial energetic functionality,especially with regard to the maintenance of electron transport during oxidative phosphorylation and in oxidative stress,acting as a free radical scavenger.We also discuss all the different apoptosis-inducing factor isoforms discovered,focusing especially on apoptosis-inducing factor 2,which is only expressed in the brain and the functions of which are starting now to be clarified.Finally,we summarized the interaction of apoptosis-inducing factor with several proteins that are crucial for both apoptosis-inducing factor functions(prosurvival and pro-apoptotic)and that are highly important in order to develop promising therapeutic targets for improving outcomes after perinatal brain injury. | Juan Rodriguez Tao Li Yiran Xu Yanyan Sun Changlian Zhu | 2021 | Neural Regeneration Research2021，16，2： | 11 |
| 16 | 哥斯达黎加森林生态服务补偿机制演进及启示显示文摘通过分析哥斯达黎加森林生态服务补偿机制演进历程,总结出其项目类型多样、参加者自主性强、项目合同规范高效、项目资金来源渠道丰富、补偿标准合理、从自愿的补偿向强制性支付转变等对我国有益的启示,并在此基础上提出改进我国森林生态效益补偿机制的建议。 | 朱小静 Carlos Manuel Rodriguez 张红霄 汪海燕 | 2012 | 世界林业研究2012，25，6： | 9 |
| 17 | 多形性黄色瘤型星形细胞瘤:自然病史和长期随访显示文摘作者回顾性研究74例多形性黄色瘤型星形细胞瘤(PXA)组织学问变特征和BRAFV600E突变的预后意义。患者平均诊断年龄21.5岁,包括31例儿童和43例成人,随访中位时间为7.6年。间变特征(PXA—AF)定义为核分裂指数≥5个/10HPF和(或)伴有坏死,共有33例。作者将其中60例进行免疫组化和(或)分子分析,发现其中39例BRAFV600E突变,且这39例IDH1(R132H)均为阴性。 | Ida C M Rodriguez F J Burger P C 李晓玲 王行富 | 2015 | 临床与实验病理学杂志2015，31，11： | 9 |
| 18 | NLRP3 inflammasome blockade reduces adipose tissue inflammation and extracellular matrix remodeling显示文摘The NLRP3-IL-1β pathway plays an important role in adipose tissue(AT)-induced inflammation and the development of obesityassociated comorbidities.We aimed to determine the impact of NLRP3 on obesity and its associated metabolic alterations as well as its role in adipocyte inflammation and extracellular matrix(ECM)remodeling.Samples obtained from 98 subjects were used in a case-control study.The expression of different components of the inflammasome as well as their main effectors and inflammation-and ECM remodeling-related genes were analyzed.The impact of blocking NLRP3 using siRNA in lipopolysaccharide(LPS)-mediated inflammation and ECM remodeling signaling pathways was evaluated.We demonstrated that obesity(P<0.01),obesity-associated T2D(P<0.01)and NAFLD(P<0.05)increased the expression of different com ponents of the inflammasome as well as the expression and release of IL-1β and IL-18 in AT.We also found that obese patients with T2D exhibited increased(P<0.05)hepatic gene expression levels of NLRP3,IL1B and IL18.We showed that NLRP3,but not NLRP1,is regulated by inflammation and hypoxia in visceral adipocytes.We revealed that the inhibition of NLRP3 in human visceral adipocytes significantly blocked(P<0.01)LPS-induced inflammation by downregulating the mRNA levels of CCL2,IL1B,IL6,IL8,S100A8,S100A9,TLR4 and TNF as well as inhibiting(P<0.01)the secretion of IL1-β into the culture medium.Furthermore,blocking NLRP3 attenuated(P<0.01)the LPS-induced expression of important molecules involved in AT fibrosis(COL1A1,COL4A3,COL6A3 and MMP2).These novel findings provide evidence that blocking the expression of NLRP3 reduces AT inflammation with significant fibrosis attenuation. | Xabier Unamuno Javier Gomez-Ambrosi Beatriz Ramirez Amaia Rodriguez Sara Becerril Victor Valenti Rafael Moncada Camilo Silva Javier Salvador Gema Fruhbeck Victoria Catalan | 2021 | Cellular & Molecular Immunology2021，18，4： | 9 |
| 19 | Optimized Nonbismuth Quadruple Therapies Cure Most Patients With Helicobacter pylori Infection in Populations With High Rates of Antibiotic Resistance显示文摘 | Javier Molina–Infante Marco Romano Miguel Fernandez–Bermejo Alessandro Federico Antonietta G. Gravina Liliana Pozzati Elena Garcia–Abadia Gema Vinagre–Rodriguez Carmen Martinez–Alcala Moises Hernandez–Alonso Agnese Miranda Maria Rosaria Iovene Carmen Pazo | 2013 | Gastroenterology2013，，1： | 8 |
| 20 | 左室血栓的临床、影像和病理学特征:在经手术或病理确诊病例中比较对比增强MRI、经胸超声心动图和经食管超声心动图 | Srichai M.B. Junor C. Rodriguez L.L. R.D. White 刘少伟 | 2006 | 世界核心医学期刊文摘(心脏病学分册)2006，0，11： | 8 |
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