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| 1 | No Significant Association of 14 Candidate Genes With Schizophrenia in a Large European Ancestry Sample: Implications for Psychiatric Genetics显示文摘 | Sanders Alan R Duan Jubao Levinson Douglas F Shi Jianxin He Deli Hou Cuiping Burrell Gregory J Rice John P Nertney Deborah A Olincy Ann Rozic Pablo Vinogradov Sophia Buccola Nancy G Mowry Bryan J Freedman Robert Amin Farooq Black Donald W | 2008 | The American Journal of Psychiatry2008，，4： | 1 |
| 2 | Regulation of mammalian circadian behavior by noo - red, non - core, ocular photorecepters 显示文摘 | Freedman MS Robert J Soui B | 1999 | Science1999，284，5413： | 1 |
| 3 | Frontotemporal lobar degeneration: A consensus on clinical diagnostic criteria显示文摘 | D. Neary J. S. Snowden L. Gustafson U. Passant D. Stuss S. Black M. Freedman A. Kertesz P. H. Robert M. Albert K. Boone B. L. Miller J. Cummings D. F. Benson | 1998 | Neurology1998，，： | 1 |
| 4 | Genomic Organization and Partial Duplication of the Human α7 Neuronal Nicotinic Acetylcholine Receptor Gene (CHRNA7)显示文摘 | Judith Gault Misi Robinson Ralph Berger Carla Drebing Judith Logel Jan Hopkins Ted Moore Suzette Jacobs Jennifer Meriwether Mun Jun Choi Eun Jung Kim Katy Walton Karin Buiting Ashley Davis Charles Breese Robert Freedman Sherry Leonard | 1998 | Genomics1998，，2： | 1 |
| 5 | Contemporary utilization and outcomes of intra-aortic balloon counterpulsation in acute myocardial infarction显示文摘 | Gregg W Stone E.Magnus Ohman Michael F Miller Debra L Joseph Jan T Christenson Marc Cohen Philip M Urban Ramachandra C Reddy Robert J Freedman Karen L Staman James J Ferguson | 2003 | Journal of the American College of Cardiology2003，，11： | 1 |
| 6 | Contemporary utilization and outcomes of intra-aortic balloon counterpulsation in acute myocardial infarction显示文摘 | Gregg W Stone E.Magnus Ohman Michael F Miller Debra L Joseph Jan T Christenson Marc Cohen Philip M Urban Ramachandra C Reddy Robert J Freedman Karen L Staman James J Ferguson | 2003 | Journal of the American College of Cardiology2003，，： | 1 |
| 7 | 产前胆碱水平与精神分裂症的发生(英文)显示文摘背景:医学的最终目的是在人群中对疾病进行一级预防,这对精神分裂症而言似乎是难以实现的。精神分裂症的病因早在胎儿大脑发育时期就开始出现,远远早于病症的出现。基因因素是精神分裂症的主要病因之一,作用于烟碱型胆碱能受体上的胆碱能神经递质的传递是与此遗传风险相关的病理生理机制之一。在胎儿大脑发育过程中,胆碱可以激活上述烟碱型受体。因而通过孕期膳食补充胆碱可能是在更早期预防精神分裂症发生发展的一种干预手段。目的:对有关孕期和胎儿大脑发育过程中补充胆碱或胆碱水平与疾病关系的文献进行综述。方法:在Medline上检索评估胆碱对人类胎儿发育影响的研究,还检索了有关精神分裂症的其他产前危险因素的研究以及胆碱能神经传递对精神分裂症病理生理作用的研究。结果:孕期饮食中胆碱含量要高,因为膜的生物合成、一碳单位代谢和胆碱能神经传递等都需要胆碱。高浓度胆碱能够直接作为烟碱型受体激动剂,这对正常的大脑环路发育是至关重要的。在孕中、晚期的膳食中补充磷脂酰胆碱可以增强上述胆碱的功能,更有利于胎儿的发育。有研究观察到膳食补充磷脂酰胆碱能改善抑制性神经元功能,而该功能不足与精神分裂症和注意缺陷障碍相关。结论:产前膳食补充磷脂酰胆碱,提倡食用富含胆碱的食物(肉类、大豆、鸡蛋),可能会促进胎儿大脑发育,从而降低今后发生精神疾病的风险。这种短期(6个月)干预风险低,特别适用于普通人群。这类似于以往研究发现叶酸能预防腭裂,因而建议产前补充相应的药物并改善饮食。然而,数十年内还无法获得产前补充胆碱有效性的确切证据(因为精神分裂症的发生要滞后约20年),所以公共卫生领域的官员只能根据现有的有限信息来决定是否提倡补充胆碱。 | Robert FREEDMAN Randal G.ROSS | 2015 | 上海精神医学2015，27，2： | 1 |
| 8 | The current practice of intra-aortic balloon counterpulsation: results from the Benchmark Registry显示文摘 | James J Ferguson Marc Cohen Robert J Freedman Gregg W Stone Michael F Miller Debra L Joseph E.Magnus Ohman | 2001 | Journal of the American College of Cardiology2001，，5： | 1 |
| 9 | A modification of karmarkar’s linear programming algorithm显示文摘 | Robert J. Vanderbei Marc S. Meketon Barry A. Freedman | 1986 | Algorithmica (-)1986，，1： | 1 |
| 10 | Prospects for improving future mental health of children through prenatal maternal micronutrient supplementation in China显示文摘Prenatal micronutrients in pregnant women’s diets,including supplements,have an essential role in fetal brain development and may reduce the risk of mental disorders in offspring.Folic acid,vitamin D,omega‐3 fatty acids,and choline have been investigated for this purpose.Folic acid supplementation throughout pregnancy has well‐established positive effects.Vitamin D,administered to the mother before birth or to the newborn,has also been shown to reduce the risk of neurodevelopmental disorders.Omega‐3 fatty acids during pregnancy have a more uncertain role,with recent trials questioning a beneficial effect on cognition and attention deficit disorder,despite positive effects on prematurity and neonatal wheezing prevention.Choline supplementation is associated with positive effects on cognition and behavior,including early behaviors associated with the development of autism and schizophrenia.There is no experience yet with COVID‐19,but adverse effects on fetal brain development of most common coronaviruses are mitigated by higher choline levels.Maternal dietary supplementation of nutrients is a benign and inexpensive intervention in pregnancy to prevent life‐long disability from mental illness.Use of dietary supplements in poorer,rural areas of China is below recommendations.Physicians,midwives,and public health officials in China can promote prenatal nutrient supplementation to reduce the future burden of mental illnesses that might be prevented before birth. | Ying Li Robert Freedman | 2020 | Pediatric Investigation2020，4，2： | 0 |
| 11 | 核磁共振(NMR)测井的进展显示文摘1前言
本文总结了核磁共振(NMR)测井技术,对象是那些想了解NMR测井地层评价能力的非专业人士。本文的目的是阐明NMR的基本测量原理和解释方法(解释时必须理解NMR地层评价技术),并讨论这些方法的几个实例。 | Robert Freedman 孙逊(译) 赵文杰(校) | 2007 | 测井与射孔2007，10，1： | 0 |
| 12 | 核磁共振测井进展显示文摘0引言
本文简介核磁共振测井(NMR)获取地层评价信息技术,讲述NMR测井储层评价技术的基本测量原理和解释方法,讨论这种方法的几个应用实例。
脉冲NMR测井于20世纪90年代引入,它给储层的流体性质、岩石和流体,岩石接触关系分析带来了革命性变革。这项技术引进得非常及时,它正好出现在70年代疯狂钻井而油田快速减产,急切需要新的仪器评价勘探和开发后比较复杂储层的情况下。自引入脉冲NMR测井后,它带来了许多独特的地层评价方法,得到了长足的发展。现在贝克休斯、哈里伯顿和斯伦贝谢等许多的公司都提供NMR测井服务。 | Robert Freedman 肖亮(译) 陈兆明(译) 刘卫(译) | 2006 | 国外测井技术2006，21，3： | 0 |
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