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| 1 | Risk factors associated with pancreatic fistula after distal pancreatectomy, which technique of pancreatic stump closure is more beneficial?显示文摘AIM: To identify risk factors related to pancreatic fistula in patients undergoing distal pancreatectomy (DP) and to determine the effectiveness of using a stapled and a sutured closed of pancreatic stump. METHODS: Sixty-four patients underwent DP during a 10-year period. Information regarding diagnosis, operative details, and perioperative morbidity or mortality was collected. Eight risk factors were examined. RESULTS: Indications for DP included primary pancreatic disease (n = 38, 59%) and non-pancreatic malignancy (n = 26, 41%). Postoperative mortality and morbidity rates were 1.5% and 37% respectively; one patient died due to sepsis and two patients required a reoperation due to postoperative bleeding. Pancreatic fistula was developed in 14 patients (22%); 4 of fistulas were classified as Grade A, 9 as Grade B and only 1 as Grade C. Incidence of pancreatic fistula rate was significantly associated with four risk factors: pathology, use of prophylactic octreotide therapy, concomitant splenectomy, and texture of pancreatic parenchyma. The role that technique (either stapler or suture) of pancreatic stump closure plays in the development of pancreatic leak remains unclear. CONCLUSION: The pancreatic fistula rate after DP is 22%. This is reduced for patients with non-pancreatic malignancy, fibrotic pancreatic tissue, postoperative prophylactic octreotide therapy and concomitant splenectomy. | Marco Pericoli Ridolfini Sergio Alfieri Stavros Gourgiotis Dario Di Miceli Fabio Rotondi Giuseppe Quero Roberta Manghi Giovanni Battista Doglietto | 2007 | World Journal of Gastroenterology2007，13，38： | 24 |
| 2 | Surgical management of chronic pancreatitis显示文摘BACKGROUND: Treatment of chronic pancreatitis (CP) is a challenging condition for surgeons. During the last decades, increasing knowledge about pathophysiology of CP, improved results of major pancreatic resections, and integration of sophisticated diagnostic methods in clinical practice have resulted in significant changes in surgery for CP. DATA SOURCES: To detail the indications for CP surgery, the surgical procedures, and outcome, a Pubmed database search was performed. The abstracts of searched articles about surgical management of CP were reviewed. The articles could be identified and further scrutinized. Further references were extracted by cross-referencing. RESULTS: Main indications of CP for surgery are intractable pain, suspicion of malignancy, and involvement of adjacent organs. The goal of surgical treatment is to improve the quality of life of patients. The surgical approach to CP should be individualized according to pancreatic anatomy, pain characteristics, baseline exocrine and endocrine function, and medical co-morbidity. The approach usually involves pancreatic duct drainage and resection including longitudinal pancreatojejunostomy, pancreatoduodenectomy (Whipple's procedure), pylorus-preserving pancreatoduodenectomy, distal pancreatectomy, total pancreatectomy, duodenum- preserving pancreatic head resection (Beger's procedure), and local resection of the pancreatic head with longitudinal pancreatojejunostomy (Frey's procedure). Non-pancreatic and endoscopic management of pain has also been advocated. CONCLUSIONS: Surgical procedures provide long-term pain relief, a good postoperative quality of life withpreservation of endocrine and exocrine pancreatic function, and are associated with low early and late mortality and morbidity. In addition to available results from randomized controlled trials, new studies are needed to determine which procedure is the most effective for the management of patients with CP. | Stavros Gourgiotis Stylianos Germanos Marco Pericoli Ridolfini | 2007 | Hepatobiliary & Pancreatic Diseases International2007，6，2： | 8 |
| 3 | Presentation and management of pancreatic cystic neoplasms显示文摘 | Gourgiotis S Germanos S Ridolfini MP | | 0，，06： | 1 |
| 4 | Late complication after colon self-expandable metal stent placement: a case report显示文摘 | Pericoli Ridolfini M Sofo L Di Giorgio A | 2007 | Minerva Chit2007，62，1： | 1 |
| 5 | Gastrointestinal stromal tumors显示文摘 | Ridolfini MP Cassano A Ricci R | | 0，，02： | 1 |
| 6 | First experiments with lithium fimiter on ftu 显示文摘 | Apieella M L Mazzitelli G Ridolfini V P | 2007 | Journal of Nuclear Materials2007，363，5： | 1 |
| 7 | Presentation and man- agement of pancreatic cystic neoplasms 显示文摘 | Gourgiotis S Germanos S Ridolfini MP | 2007 | J Clin Gastroenterel2007，41，6： | 1 |
| 8 | Intraductal papillarymucinous neoplasms of the pancreas- Review 显示文摘 | Gourgiotis S Ridolfini MP Germanos S | 2007 | Eur J SurgOncol2007，33，1： | 1 |
| 9 | Intraductal papilla-ry mutinous neoplasms of the pancreas 显示文摘 | GOURGIOTS S RIDOLFINI MP GERMANOS S | 2007 | Eur J Surg Oncol2007，33，6： | 1 |
| 10 | Presentation, treatment and prognosis of intraductal papillary mucinous neoplasm 显示文摘 | Ridolfini MP Gourgiotis S Alfieri S | 2007 | Ann hal Chir2007，78，4： | 1 |
| 11 | Pancreatoduodenectomy for Tumors of Vater’s Ampulla: Report on 94 Consecutive Patients显示文摘 | Andrea Di Giorgio M.D. Sergio Alfieri M.D. Fabio Rotondi M.D. Francesco Prete M.D. Dario Di Miceli M.D. Marco Pericoli Ridolfini M.D. Fausto Rosa M.S. Marcello Covino M.D. Giovanni Battista Doglietto M.D | 2005 | World Journal of Surgery2005，，4： | 1 |
| 12 | Intraductal papillary mucinous neoplasms of the pancreas 显示文摘 | Gourgiotis S Ridolfini MP Gennanos S | 2007 | Eur J Surg Ortcol2007，33，6： | 1 |
| 13 | Presentation and management of pancreatic cystic neoplasms显示文摘 | Gourgiotis S Germanos S Ridolfini MP | 2007 | J Clin Gastroenterol2007，41，6： | 1 |
| 14 | Influence of Preservation Versus Division of Ilioinguinal, Iliohypogastric, and Genital Nerves During Open Mesh Herniorrhaphy: Prospective Multicentric Study of Chronic Pain显示文摘 | Sergio Alfieri Fabio Rotondi Andrea Di Giorgio Uberto Fumagalli Antonio Salzano Dario Di Miceli Marco Pericoli Ridolfini Antonio Sgagari Giovannibattista Doglietto | 2006 | Annals of Surgery2006，，4： | 1 |
| 15 | Pancreatoduodenectomy for Tumors of Vater’s Ampulla: Report on 94 Consecutive Patients显示文摘 | Andrea Di Giorgio M.D. Sergio Alfieri M.D. Fabio Rotondi M.D. Francesco Prete M.D. Dario Di Miceli M.D. Marco Pericoli Ridolfini M.D. Fausto Rosa M.S. Marcello Covino M.D. Giovanni Battista Doglietto M.D | 2005 | World Journal of Surgery2005，，4： | 1 |
| 16 | Intraductal papillary mucinous neoplasms of the pancreas显示文摘 | Gourgiotis S Ridolfini MP Germanos S | 2007 | Eur J Surg Oncol2007，33，6： | 1 |
| 17 | Intraductal papillary mucinous neoplasms of the pancreas显示文摘 | Gourgiotis S Ridolfini MP Germanos S | 2007 | Eur J Surg Oncol2007，33，： | 1 |
| 18 | 查看详情显示文摘 | Pericoli Ridolfini V Ekedahl A SKErents Mailloux J Podda S Sarazin Y Tuccillo A A | | 0，，： | 1 |
| 19 | Presentation,treatment and prognosis of intraductal papillary mucinous neoplasm显示文摘 | Ridolfini MP Gourgiotis S Alfieri S | 2007 | Ann Ital Chir2007，78，4： | 1 |
| 20 | Pancreatoduodenectomy for Tumors of Vater’s Ampulla: Report on 94 Consecutive Patients显示文摘 | Andrea Di Giorgio M.D. Sergio Alfieri M.D. Fabio Rotondi M.D. Francesco Prete M.D. Dario Di Miceli M.D. Marco Pericoli Ridolfini M.D. Fausto Rosa M.S. Marcello Covino M.D. Giovanni Battista Doglietto M.D | 2005 | World Journal of Surgery2005，，4： | 1 |
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