|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Role of wide-field autofluorescence imaging and scanning laser ophthalmoscopy in differentiation of choroidal pigmented lesions显示文摘·AIM:Toevaluatethe diagnostic properties of wide-field fundus autofluorescence(FAF) scanning laser ophthalmoscope(SLO) imaging for differentiating choroidal pigmented lesions.·METHODS: A consecutive series of 139 patients were included, 101 had established choroidal melanoma with13 untreated lesions and 98 treated with radiotherapy.Thirty-eight had choroidal nevi. All patients underwent a full ophthalmological examination, undilated wide-field imaging, FAF and standardized US examination. FAF images and imaging characteristics from SLO were correlated with the structural findings in the two patient groups.·RESULTS: Mean FAF intensity of melanomas was significantly lower than the FAF of choroidal nevi. Only 1out of 38 included eyes with nevi touched the optic disc compared to 31 out of 101 eyes with melanomas. In 18 out of 101 melanomas subretinal fluid was seen at the pigmented lesion compared to none seen in eyes with confirmed choroidal nevi. In 'green laser separation', a trend towards more mixed FAF appearance of melanomas compared to nevi was observed. The mean maximal and minimal transverse and longitudinal diameters of melanomas were significantly higher than those of nevi.·CONCLUSION: Wide-field SLO and FAF imaging may be an appropriate non-invasive diagnostic screening tool to differentiate benign from malign pigmented choroidal lesions. | Lukas Reznicek Carmen Stumpf Florian Seidensticker Anselm Kampik Aljoscha S Neubauer Marcus Kernt | 2014 | International Journal of Ophthalmology(English edition)2014，7，4： | 3 |
| 2 | Multimodal imaging in acute retinal ischemia: spectral domain OCT, OCT-angiography and fundus autofluorescence显示文摘AIM: To describe retinal findings of various imaging modalities in acute retinal ischemia. METHODS: Fluorescein angiography(FA), spectral domain optical coherence tomography(SD-OCT), OCTangiography(OCT-A) and fundus autofluorescence(FAF) images of 13 patients(mean age 64y, range 28-86y) with acute retinal ischemia were evaluated. Six suffered from branch arterial occlusion, 2 had a central retinal artery occlusion, 2 had a combined arteriovenous occlusions, 1 patient had a retrobulbar arterial compression by an orbital haemangioma and 2 patients showed an ocular ischemic syndrome.RESULTS: All patients showed increased reflectivity and thickening of the ischemic retinal tissue. In 10 out of 13 patients SD-OCT revealed an additional highly reflective band located within or above the outer plexiform layer. Morphological characteristics were a decreasing intensity with distance from the fovea, partially segmental occurrence and manifestation limited in time. OCT-A showed a loss of flow signal in the superficial and deep capillary plexus at the affected areas. Reduced flow signal was detected underneath the regions with retinal edema. FAF showed areas of altered signal intensity at the posterior pole. The regions of decreased FAF signal corresponded to peri-venous regions. CONCLUSION: Multimodal imaging modalities in retinal ischemia yield characteristic findings and valuable diagnostic information. Conventional OCT identifies hyperreflectivity and thickening and a mid-retinal hyperreflective band is frequently observed. OCT-A examination reveals demarcation of the ischemic retinal area on the vascular level. FAF shows decreased fluorescence signal in areas of retinal edema often corresponding to peri-venous regions. | Nikolaus Feucht Daniel Zapp Lukas Reznicek Chris P.Lohmann Mathias Maier Christian S.Mayer | 2018 | International Journal of Ophthalmology(English edition)2018，11，9： | 3 |
| 3 | Structure-function relationship comparison between retinal nerve fibre layer and Bruch's membrane opening-minimum rim width in glaucoma显示文摘AIM:To evaluate and compare structural optical coherence tomography(OCT)-based parameters,such as Bruch's membrane opening-minimum rim width(BMO-MRW),and retinal nerve fiber layer(RNFL) thickness in glaucoma patients with visual field(VF) defects,and to correlate both to mean deviation(MD) values of obtained standard achromatic perimetry(SAP) examinations.METHODS:Patients with glaucoma and glaucomatous VF defects were enrolled in this prospective study and compared to age-matched healthy individuals.All study participants underwent a full ophthalmic examination and VF testing with SAP.Peripapillary RNFL thickness and BMO-MRW were acquired with SD-OCT.Correlation analyses between obtained global functional and global as well as sectorial structural parameters were calculated.RESULTS:A consecutive series of 30 glaucomatous right eyes of 30 patients were included and compared to 36 healthy right eyes of 36 individuals in the control group.Global MD of values correlated significantly with global RNFL(Pearson corr.coeff:0.632,P=0.001) and global BMO-MRW(Pearson corr.coeff:0.746,P<0.001) values in the glaucoma group.Global MD and sectorial RNFL or BMO-MRW values correlated less significantly.In the control group,MD values did not correlate with RNFL or BMO-MRW measurements.A subgroup analysis of myopic patients(>4 diopters) within the glaucoma group(n=6) revealed a tendency for higher correlations between MD and BMO-MRW than MD and RNFL measurements.CONCLUSION:In a clinical setting,RNFL thickness and BMO-MRW correlate similarly with global VF sensitivity in glaucoma patients with BMO-MRW showing higher correlations in myopic glaucoma patients. | Lukas Reznicek Sophie Burzer Andrea Laubichler Ali Nasseri Chris P Lohmann Nikolaus Feucht Michael Ulbig Mathias Maier | 2017 | International Journal of Ophthalmology(English edition)2017，10，10： | 2 |
| 4 | Correlation of leaking microaneurysms with retinal thickening in diabetic retinopathy显示文摘AIM: To investigate the contribution of fluorescein angiographic leaking microaneurysms (leak-MA) versus non-leaking microaneurysms (non-leak-MA) to retinal thickening in diabetic retinopathy.METHODS: A consecutive series of 38 eyes from 24 patients with diabetic retinopathy was included.Leak-MA and non-leak-MA in each eye were selected in pairs at corresponding topographic location.Leaking was defined by late phase fluorescein angiograms compared to early phase.Retinal thickness was measured with Heidelberg Spectralis OCT topographically aligned on early phase angiograms at the MA site and within a 1 mm circle.RESULTS: In all eyes,significant retinal thickening at the site of leaking compared to non-leaking microaneurysms was observed (356±69μm vs 318±56μm,P <0.001),showing a mean increase in thickness in the areas of leak-MA vs non-leak-MA of 38±39μm (95% confidence interval 2551μm,P<0.001).All 1mm area measurements also showed significant (P<0.001) thickening of the leak-MA with average thickness of leak-MA vs non-leak-MA as 351±67μmvs 319±59μm;minimum thickness 311±62μm vs 284±60μm;maximum thickness 389±78μm vs 352±66μm;and retina volume 26.4±6.0mmvs 23.6±3.7mm3,respectively.CONCLUSION: Leaking of microaneurysms on fluorescein angiography appears to cause focal thickening of retina,which can be measured with high-resolution OCT.Therefore,targeting leaking microaneursyms in diabetic retinopathy has the potential to reduce retinal thickening. | Lukas Reznicek Marcus Kernt Christos Haritoglou Michael Ulbig Anselm Kampik Aljoscha S Neubauer | 2011 | International Journal of Ophthalmology(English edition)2011，4，3： | 2 |
| 5 | The roles of seed banks in the persistence of Ontario's coastal plain flora显示文摘 | Keddy P A Reznicek J A | 1982 | American Journal of Botany1982，69，： | 1 |
| 6 | The role of seed banks in the persistence of Ontario's coastal plain flora显示文摘 | KEDDY P A REZNICEK A A | 1982 | American Journal of Botany1982，，69： | 1 |
| 7 | Metabolism and biliary excretion of the novel anticancer agent 10-hydroxycamptothecin in the isolated perfused rat liver显示文摘 | Platzer P Thalhammer T Reznicek G Hamilton G Zhang R Jager W | 2001 | Int J Oncol2001，19，： | 1 |
| 8 | Isolation and structure elucidation of further new saponins from Solidago Canadensis显示文摘 | Reznicek G Jurenitsch J Freiler M | 1992 | Planta Med1992，58，1： | 1 |
| 9 | 糖尿病视网膜病变中微动脉瘤荧光素渗出与视网膜增厚的关系(英文)显示文摘目的:观察糖尿病视网膜病变患者血管荧光素造影微动脉瘤处渗出与视网膜增厚的关系。方法:选取糖尿病视网膜病变患者24例38眼,首次及末次血管荧光素造影检查确定是否存在微动脉瘤荧光素渗出。根据毛细血管闭塞区的位置选取微动脉瘤荧光素渗出与未渗出各1眼配对进行对比。在微动脉瘤和直径为1mm区域使用光学相干断层成像术(OCT)测量视网膜厚度。结果:微动脉瘤荧光素渗出眼视网膜厚度明显高于未渗出眼(356±69μmvs318±56μm,P<0.001),渗出眼平均增长厚度高于未渗出眼(95%的可信区间为25~51μm,P<0.001).在直径为1mm区域,渗出眼视网膜厚度和平均增长厚度均明显高于未渗出眼(351±67μmvs319±59μm;最小值311±62μmvs284±60μm;最大值389±78μmvs352±66μm)。结论:血管荧光素造影显示微动脉瘤荧光素渗出可以增加视网膜厚度,并运用高分辨率OCT测量。因此,对糖尿病视网膜病变患者早期诊断微动脉瘤荧光素是否渗出可以抑制视网膜增厚。 | Lukas Reznicek Marcus Kernt Christos Haritoglou Michael Ulbig Anselm Kampik Aljoscha S Neubauer | 2011 | 国际眼科杂志2011，11，7： | 1 |
| 10 | Metabolism and disposition of resveratrol in the isolated pedused rat liver:Role of Mrp2 in the biliary excretion of glucronides显示文摘 | Hagenauer B Reznicek G | 2008 | J Pharm Sci2008，97，4： | 1 |
| 11 | Saponins in Cyclamen species:Configuration of cyclamiretin C and structure of isocyclamin显示文摘 | Reznicek G Jurenitsch J Robien W | 1989 | Phytochemistry1989，28，3： | 1 |
| 12 | Ethnopharmacological in vitro studies on Austria’s folk medicine—An unexplored lore in vitro anti-inflammatory activities of 71 Austrian traditional herbal drugs显示文摘 | Sylvia Vogl Paolo Picker Judit Mihaly-Bison Nanang Fakhrudin Atanas G. Atanasov Elke H. Heiss Christoph Wawrosch Gottfried Reznicek Verena M. Dirsch Johannes Saukel Brigitte Kopp | 2013 | Journal of Ethnopharmacology2013，，3： | 1 |
| 13 | Metabolism and disposition of resveratrol in the isolated perfused rat liver:Role of Mrp2,in the biliary excretion of glucuronides显示文摘 | Hagenauer B Reznicek G | 2008 | J Pharm Sci2008，97，4： | 1 |
| 14 | Four major saponins from Solidago canadensis显示文摘 | Reznicek G Jurenitsch J Pluson M | 1991 | Phytochemistry1991，30，5： | 1 |
| 15 | The focus of 'atypical glands,suspicious for malignancy' in prostatic needle biopsy specimens:incidence,histologic features,and clinical follow-up of cases diagnosed in a community practice显示文摘 | Cheville J C Reznicek M J Bostwick D G | 1997 | Am J Clin Pathol1997，108，： | 1 |
| 16 | Isolation and structure elucidation of further new saponins from Solidago Canadensis显示文摘 | Jurenitsch J Freiler M | 1992 | Planta Med1992，58，1： | 1 |
| 17 | The first structurally confirmed saponin from Solidago gigantea:structure elucidation by modern NMR techniques显示文摘 | Reznicek G Jurenitsch J Michl G | 1989 | Tetrahedron Letters1989，30，31： | 1 |
| 18 | Four major saponins from Solidago canadensis显示文摘 | Jurenitsch J Plasun M | 1991 | Phytochemistry1991，30，5： | 1 |
| 19 | Fast quantification of fla-vonoids in Filipendulae Ulmariae Fies by HPLCI ESI-MS using anonporous stationary phase显示文摘 | Pemp E Reznicek G Krenn L | 2007 | J Anal Chem2007，62，1： | 1 |
| 20 | Computerized tomo-graphy for detection and staging of localized and pathologicallydefined upper tract urothelial tumors显示文摘 | McCoy JG Honda H Reznicek M | 1991 | J Urol1991，146，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员