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| 1 | Influence of unrecorded alcohol consumption on liver cirrhosis mortality显示文摘Unrecorded alcohol includes illegally distributed alcohol as well as homemade or surrogate alcohol which is unintended for consumption by humans(e.g.,cosmetics containing alcohol).The highest unrecorded alcohol consumption occurs in Eastern Europe and some of these countries have an over proportional liver cirrhosis mortality.Compounds besides ethanol have been hypothesized as being responsible for this observation.On the other hand,chemical investigations were unable to prove that unrecorded alcohol regularly contains contaminants above toxicological thresholds.However,illegally produced spirits regularly contain higher percentages of alcohol(above 45%by volume),but for considerably less costs compared with licit beverages,potentially causing more problematic patterns of drinking.In this review,it is investigated whether patterns of drinking rather than product composition can explain the liver cirrhosis mortality rates.Statistical examination of World Health Organization country data shows that the originally detected correlation of the percentage of unrecorded alcohol consumption and liver cirrhosis mortality rates disappears when the data is adjusted for the prevalence of heavy episodic drinking.It may be concluded that there is currently a lack of data to demonstrate causality between the composition of illicit spirits(e.g.,higher levels of certain contaminants in home-produced products)and liver toxicity on a population scale.Exceptions may be cases of poisoning with antiseptic liquids containing compounds such as polyhexamethyleneguanidine,which were reported to be consumed as surrogate alcohol in Russia,leading to an outbreak of acute cholestatic liver injury,histologically different from conventional alcoholic liver disease. | Dirk W Lachenmeier Yulia B Monakhova Jürgen Rehm | 2014 | World Journal of Gastroenterology2014，20，23： | 10 |
| 2 | Global burden of alcoholic liver diseases<!-- Doctopic: Review -->显示文摘 | Jürgen Rehm Andriy V. Samokhvalov Kevin D. Shield | 2013 | Journal of Hepatology2013，，1： | 2 |
| 3 | A systematic review of the epidemiology of unrecorded alcohol consumption and the chemical composition of unrecorded alcohol显示文摘 | Jürgen Rehm Shalini Kailasapillai Elisabeth Larsen Maximilien X. Rehm Andriy V. Samokhvalov Kevin D. Shield Michael Roerecke Dirk W. Lachenmeier | 2014 | Addiction2014，，6： | 2 |
| 4 | WONCA研究论文摘要汇编——全科医生对酒精依赖的诊断:欧洲六国大型横断面研究显示文摘目的在欧洲,酒精依赖带来高死亡率和患病率,但治疗率却较低。通过筛查、简单干预、治疗、转诊,初级保健在减少酒精损害方面可以起到关键作用。本研究对欧洲初级保健机构酒精依赖的诊断情况进行调查。方法在欧洲六国搜集13 003份全科医生评估报告和9 098份患者访谈报告(其中8 476份为患者访谈与医生评估结合报告)。通过全科医生诊断和单独采用复合性国际诊断访谈(CIDI)及其他结构式访谈,对酒精依赖、并发症、卫生服务利用进行评估。以加权回归分析法,对两种诊断方法进行比较。结果通过CIDI识别的酒精依赖患者和全科医生诊断出的酒精依赖患者比例没有差异,但是重叠的患者数量并不多。医生诊断出的酒精依赖患者年龄更大,并发症(肝病、高血压)发生率更高,在社交方面更加边缘化。然而,两组评估的平均酒精摄入量和精神并发症发生率没有差异。结论全科医生能够诊断出酒精依赖,但是与CIDI的识别结果有差别。由于CIDI可能会遗漏患有严重并发症的年长酒精依赖患者,应重新检验CIDI作为参考标准的效果。 | Rehm J Allamani A Della Vedova R 本刊编辑部 | 2015 | 中国全科医学2015，18，10： | 2 |
| 5 | Alcohol under the radar: Do we have policy options regarding unrecorded alcohol?显示文摘 | Dirk W. Lachenmeier Benjamin J. Taylor Jürgen Rehm | 2010 | International Journal of Drug Policy2010，，2： | 2 |
| 6 | Global burden of alcoholic liver diseases显示文摘 | Jürgen Rehm Andriy V. Samokhvalov Kevin D. Shield | 2013 | Journal of Hepatology2013，，1： | 2 |
| 7 | Accumulation of colbalt zinc and mang nese by the estuarine green microalgae chlorella salina immobilize in alginatemicrobeads显示文摘 | Rehm H J | 1992 | Environ Sci Technol1992，26，1： | 1 |
| 8 | Biodegradation of dichloroacetic acid by freely suspended and adsorptive immobilized Xanthobacter autotrophicus GJ10 in soil显示文摘 | Meusel M Rehm H J | 1993 | Applied Microbiology and Biotechnology1993，40，1： | 1 |
| 9 | Process-engineering characterization of small-scale bub- ble columns for microbial process development显示文摘 | WEUSTER BOTZ D ALTENBACH REHM J HAWRYLEN- KO A | 2001 | Bioprocess and Biosystems Engineering2001，24，1： | 1 |
| 10 | Inhibition of Rho kinases increases directional motility of microvascular endothelial cells显示文摘 | Breyer J Samarin J Rehm M | 2012 | Bioehem Pharmacol2012，83，： | 1 |
| 11 | Global burden ofdisease attributable tomental and substance use disorders: findings from the Global Burden of Disease Study 2010 显示文摘 | Whiteford HA Degenhardt L Rehm J | 2013 | Lancet2013，382，9904： | 1 |
| 12 | Up-regulation of connective tissue growth factor in endothelial cells by the microtubule-destabilizing agent combretastatin A-4显示文摘 | Samarin J Rehm M Krueger B | 2009 | Mol Cancer Ther2009，7，2： | 1 |
| 13 | Smoking-attributable mortality and expected years of life lost in Canada 2002:conclusions for prevention and policy 显示文摘 | Baliunas D Patra J Rehm J ct al | 2007 | Chronic Dis Can2007，27，： | 1 |
| 14 | Production of functionalized biopolyester granules by recombinant Lactococcus lactis 显示文摘 | MIFUNE J GRAGE K REHM B H | 2009 | Appl Environ Microbiol2009，75，14： | 1 |
| 15 | Degradation of polycyclic aromatic hydrocarbons by an immobilized mixed bacterial culture 显示文摘 | Wiesel I Wubker S M Rehm H J | 1993 | Applied Microbiology and Biotechnology1993，39，1： | 1 |
| 16 | Harmful alcohol use显示文摘 | Gmel G Rehm J | 2003 | Epidemiology in Alcohol Research2003，27，1： | 1 |
| 17 | The cardioprotective association of' average al- cohol consumption and ischaemie heart disease:a systematic review and meta-analysis 显示文摘 | Roerecke M Rehm J | 2012 | Addiction2012，107，7： | 1 |
| 18 | ZZ polyester beads: an efficient and simple method for purifying IgG from mouse hybridoma supematants 显示文摘 | Lewis J G Rehm B H | 2009 | J Immunol Methods2009，346，12： | 1 |
| 19 | Alcohol and all-cause mortality:A pooled analysis显示文摘 | Rehm J Gutjahr E Gmel G | 2001 | Contemporary Drug Problems2001，28，： | 1 |
| 20 | Biodegradation of phenanthrene by Arthrobacter polychromogenes isolated from a contaminated soil 显示文摘 | KEUTH S REHM H J | 1991 | Applied Microbiology and Biotechnology1991，34，： | 1 |
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