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| 1 | Pathogenic role of myeloperoxidase in acute pancreatitis显示文摘BACKGROUND:Myeloperoxidase(MPO)has been implicated in promoting tissue damage in various inflammatory diseases.However,MPO blood levels in relation to the severity of acute pancreatitis(AP)and its time-course have not been studied.The present study aimed to determine the role of MPO in AP.METHODS:We studied 86 patients with AP(48 patients with mild and 38 with severe pancreatitis)and 18 controls(volunteers).The relations of serum MPO levels to cytokine level,severity,and time-course of pancreatitis were studied.The serum level of MPO and cytokines were measured by MPO-EIA and cytokines ELISA,respectively.RESULTS:The highest level of MPO was noted at the first day in patients with severe AP.A decrease of MPO blood level occurred during the first three days in all patients with necrotizing pancreatitis.The development of pancreatitis-associated lung injury and purulent complications was accompanied by increased MPO levels.Administration of pentoxifylline significantly reduced the MPO blood level,which was clearly correlated with the levels of proinflammatory cytokines in the two groups of patients.CONCLUSIONS:The results of the present study showed the MPO blood level is dependent on the severity of AP and on cytokine blood levels.Pentoxifylline in the complex management of severe AP may improve the results of treatment. | Serge Chooklin Andriy Pereyaslov Ihor Bihalskyy | 2009 | Hepatobiliary & Pancreatic Diseases International2009，8，6： | 8 |
| 2 | 圆柱绕流气动声的偶极子及四极子源法定量研究显示文摘以亚临界三维圆柱绕流的气动噪声为对象,研究声类比理论中偶极子及四极子源模型在预测低Mach数流动气动声的可靠性及准确性。使用大涡模拟(LES)得到非定常流场,并依据声类比中的Curle等效偶极子面源和Lighthill四极子体源模型,提取相应的声源数据,经Fourier变换得到涡脱落频率处的声源信息,进而定量预测圆柱绕流的气动声。结果表明:Curle模型的结果与实验结果吻合良好,Lighthill体源模型预测的准确性依赖于声源区域截断,不恰当的声源截断将导致错误的声场预测。 | 蔡建程 潘杰 鄂世举 Kryzhanovskyi Andrii 焦卫东 | 2016 | 声学学报2016，41，3： | 6 |
| 3 | Role of 3'-untranslated region translational control in cancer development, diagnostics and treatment显示文摘The messenger RNA 3'-untranslated region(3'UTR)plays an important role in regulation of gene expres-sion on the posttranscriptional level. The 3'UTR con-trols gene expression via orchestrated interactionbetween the structural components of mRNAs(cis-ele-ment) and the specific trans-acting factors(RNA bind-ing proteins and non-coding RNAs). The crosstalk ofthese factors is based on the binding sequences and/or direct protein-protein interaction, or just functionalinteraction. Much new evidence that has accumulatedsupports the idea that several RNA binding factors canbind to common mRNA targets: to the non-overlappingbinding sites or to common sites in a competitive fash-ion. Various factors capable of binding to the sameRNA can cooperate or be antagonistic in their actions.The outcome of the collective function of all factorsbound to the same mRNA 3'UTR depends on manycircumstances, such as their expression levels, affinity to the binding sites, and localization in the cell, which can be controlled by various physiological conditions. Moreover, the functional and/or physical interactions of the factors binding to 3'UTR can change the character of their actions. These interactions vary during the cell cycle and in response to changing physiological condi-tions. Abnormal functioning of the factors can lead to disease. In this review we will discuss how alterations of these factors or their interaction can affect cancer development and promote or enhance the malignant phenotype of cancer cells. Understanding these altera-tions and their impact on 3'UTR-directed posttran-scriptional gene regulation will uncover promising new targets for therapeutic intervention and diagnostics. We will also discuss emerging new tools in cancer di-agnostics and therapy based on 3'UTR binding factors and approaches to improve them. | Andrii Vislovukh Thaiz Rivera Vargas Anna Polesskaya Irina Groisman | 2014 | World Journal of Biological Chemistry2014，5，1： | 6 |
| 4 | Nano-Structured Carbide-Derived Carbon Films and Their Tribology显示文摘Carbide-derived carbon (CDC) is a form of carbon produced by reacting metal carbides, such as SiC or TiC, with halogens at temperatures high enough to produce fast kinetics, but too low to permit the re- arrangement of the carbon atoms into an equilibrium graphitic structure. The structure of CDC is derivative of the original carbide structure and contains nanoscale porosity and both sp2 and sp3 bonded carbon in a variety of nanoscale structures. CDC can be produced as a thin film on hard carbides to improve their tri- bological performance. CDC coatings are distinguished by their low friction coefficients and high wear resis- tance in many important industrial environments and by their resistance to spallation and delamination. The tribology of CDC coatings on SiC surfaces is described in detail. | Michael McNallan Daniel Ersoy Ranyi Zhu Allen Lee Christopher White Sascha Welz Yury Gogotsi Ali Erdemir Andriy Kovalchenko | 2005 | Tsinghua Science and Technology2005，10，6： | 6 |
| 5 | Predictors of spine deformity progression in adolescent idiopathic scoliosis: A systematic review with meta-analysis显示文摘AIM: To evaluate published data on the predictors of progressive adolescent idiopathic scoliosis(AIS) in order to evaluate their efficacy and level of evidence. METHODS: Selection criteria:(1) study design: randomized controlled clinical trials, prospective cohort studies and case series, retrospective comparative and none comparative studies;(2) participants: adolescents with AIS aged from 10 to 20 years; and(3) treatment: observation, bracing, and other. Search method: Ovid MEDLINE, Embase, the Cochrane Library, Pub Medand patent data bases. All years through August 2014 were included. Data were collected that showed an association between the studied characteristics and the progression of AIS or the severity of the spine deformity. Odds ratio(OR), sensitivity, specificity, positive and negative predictive values were also collected. A metaanalysis was performed to evaluate the pooled OR and predictive values, if more than 1 study presented a result. The GRADE approach was applied to evaluate the level of evidence.RESULTS: The review included 25 studies. All studies showed statistically significant or borderline association between severity or progression of AIS with the following characteristics:(1) An increase of the Cobb angle or axial rotation during brace treatment;(2) decrease of the rib-vertebral angle at the apical level of the convex side during brace treatment;(3) initial Cobb angle severity(> 25o);(4) osteopenia;(5) patient age < 13 years at diagnosis;(6) premenarche status;(7) skeletal immaturity;(8) thoracic deformity;(9) brain stem vestibular dysfunction; and(10) multiple indices combining radiographic, demographic, and physiologic characteristics. Single nucleotide polymorphisms of the following genes:(1) calmodulin 1;(2) estrogen receptor 1;(3) tryptophan hydroxylase 1;(3) insulin-like growth factor 1;(5) neurotrophin 3;(6) interleukin-17 receptor C;(7) melatonin receptor 1B, and(8) Scoli Score test. Other predictors included:(1) impairment of melatonin signaling in osteoblasts and peripheral blood mononuclear cells(PBMC);(2) G-protein signaling dysfunction in PBMC; and(3) the level of platelet calmodulin. However, predictive values of all these findings were limited, and the levels of evidence were low. The pooled result of brace treatment outcomes demonstrated that around 27% of patents with AIS experienced exacerbation of the spine deformity during or after brace treatment, and 15% required surgical correction. However, the level of evidence is also low due to the limitations of the included studies.CONCLUSION: This review did not reveal any methods for the prediction of progression in AIS that could be recommended for clinical use as diagnostic criteria. | Andriy Noshchenko Lilian Hoffecker Emily M Lindley Evalina L Burger Christopher MJ Cain Vikas V Patel Andrew P Bradford | 2015 | World Journal of Orthopedics2015，6，7： | 4 |
| 6 | Electrodeposition of Al from a 1-butylpyrrolidine-AlCl_3 ionic liquid显示文摘The addition of 1-butylpyrrolidine to AlCl_3 results in the formation of an electrolyte that is suited to Al deposition.The feasibility of electrodepositing Al from the synthesized electrolyte was investigated.Several compositions of AlCl_3 and 1-butylpyrrolidine were prepared for this purpose.These mixtures show a different phase behavior at various compositions of AlCl_3 and 1-butylpyrrolidine.IR,Raman and NMR spectroscopy were employed to characterize the synthesized liquids.Among the prepared compositions,1:1.2 mol ratio of 1-butylpyrrolidine:AlCl_3 and the upper phase of 1:1.3 mol ratio of 1-butylpyrrolidine:AlCl_3 were found to be suitable for Al electrodeposition at room temperature(RT).Uniform and thick( mm thick) layers of Al were obtained on copper at RT.Al deposition occured from the cationic species of AlCl_3 xLty(where x r 2,y ? 1–2,and L ? 1-butylpyrrolidine) in this electrolyte.This behavior is contrary to the well investigated classic AlCl_3 based ionic liquids,where the deposition of Al occurs mainly from anionic Al2 Cl 7ions. | Giridhar Pulletikurthi Bjorn Bodecker Andriy Borodin Bernd Weidenfeller Frank Endres | 2015 | Progress in Natural Science:Materials International2015，25，6： | 4 |
| 7 | 甲醇喷雾湍流反应流的JPDF数值模拟显示文摘喷雾湍流燃烧过程中,液滴、湍流和化学反应之间强烈耦合,物理化学机理非常复杂。本文将速度-标量-频率联合概率密度函数JPDF输运方程方法应用于两相喷雾湍流反应流问题,利用火焰面模型解耦流动和化学反应动力学的耦合关系,建立起相应的数值计算模型。采用Monte-Carlo数值计算方法,针对澳大利亚悉尼大学Masri等人以甲醇为燃料所进行的湍流喷雾燃烧值班火焰这一试验进行了数值模拟,通过与Fluent下的计算结果及试验结果的对比分析,验证了本文所建模型的准确性。 | 何志霞 王谦 RYBAKOV Andriy MAAS Ulrich | 2011 | 工程热物理学报2011，32，3： | 3 |
| 8 | A workflow for Sustainable Development Goals indicators assessment based on high-resolution satellite data显示文摘For evaluating the progresses towards achieving the Sustainable Development Goals(SDGs),a global indicator framework was developed by the UN Inter-Agency and Expert Group on Sustainable Development Goals Indicators.In this paper,we propose an improved methodology and a set of workflows for calculating SDGs indicators.The main improvements consist of using moderate and high spatial resolution satellite data and state-of-the-art deep learning methodology for land cover classification and for assessing land productivity.Within the European Network for Observing our Changing Planet(ERA-PLANET),three SDGs indicators are calculated.In this research,harmonized Landsat and Sentinel-2 data are analyzed and used for land productivity analysis and yield assessment,as well as Landsat 8,Sentinel-2 and Sentinel-1 time series are utilized for crop mapping.We calculate for the whole territory of Ukraine SDG indicators:15.1.1–‘Forest area as proportion of total land area’;15.3.1–‘Proportion of land that is degraded over total land area’;and 2.4.1–‘Proportion of agricultural area under productive and sustainable agriculture’.Workflows for calculating these indicators were implemented in a Virtual Laboratory Platform.We conclude that newly available high-resolution remote sensing products can significantly improve our capacity to assess several SDGs indicators through dedicated workflows. | Nataliia Kussul Mykola Lavreniuk Andrii Kolotii Sergii Skakun Olena Rakoid Leonid Shumilo | 2020 | International Journal of Digital Earth2020，13，2： | 3 |
| 9 | Global burden of alcoholic liver diseases<!-- Doctopic: Review -->显示文摘 | Jürgen Rehm Andriy V. Samokhvalov Kevin D. Shield | 2013 | Journal of Hepatology2013，，1： | 2 |
| 10 | A systematic review of the epidemiology of unrecorded alcohol consumption and the chemical composition of unrecorded alcohol显示文摘 | Jürgen Rehm Shalini Kailasapillai Elisabeth Larsen Maximilien X. Rehm Andriy V. Samokhvalov Kevin D. Shield Michael Roerecke Dirk W. Lachenmeier | 2014 | Addiction2014，，6： | 2 |
| 11 | Global burden of alcoholic liver diseases显示文摘 | Jürgen Rehm Andriy V. Samokhvalov Kevin D. Shield | 2013 | Journal of Hepatology2013，，1： | 2 |
| 12 | Oxidation of diesel soot on binary oxide Cu Cr(Co)-based monoliths显示文摘Binary oxide systems(Cu Cr2O4, Cu Co2O4), deposited onto cordierite monoliths of honeycomb structure with a second support(finely dispersed Al2O3), were prepared as filters for catalytic combustion of diesel soot using internal combustion engine's gas exhausts(O2, NOx, H2 O, CO2) and O3 as oxidizing agents. It is shown that the second support increases soot capacity of aforementioned filters, and causes dispersion of the particles of spinel phases as active components enhancing thereby catalyst activity and selectivity of soot combustion to CO2. Oxidants used can be arranged with reference to decreasing their activity in a following series: O3 NO2> H2 O > NO > O2> CO2. Ozone proved to be the most efficient oxidizing agent: the diesel soot combustion by O3 occurs intensively(in the presence of copper chromite based catalyst) even at closing to ambient temperatures.Results obtained give a basis for the conclusion that using a catalytic coating on soot filters in the form of aforementioned binary oxide systems and ozone as the initiator of the oxidation processes is a promising approach in solving the problem of comprehensive purification of automotive exhaust gases at relatively low temperatures, known as the 'cold start' problem. | Sergiy O.Soloviev Andriy Y.Kapran Yaroslava P.Kurylets | 2015 | Journal of Environmental Sciences2015，27，2： | 2 |
| 13 | The Antiviral Action of Polyhexamethylene Guanidine Derivatives显示文摘 | Andriy Lysytsya Mykola Mandygra | 2014 | Journal of Life Sciences2014，8，1： | 2 |
| 14 | Investigation of the different weight models in Kalman filter:A case study of GNSS monitoring results显示文摘During geodetic monitoring with GNSS technology one of important steps is the correct processing and analysis of the measured displacements. We used the processing method of Kalman filter smoothing algorithm, which allows to evaluate not only displacements, but also the speed, acceleration, and other characteristics of the deformation model. One of the important issues is the calculation of the observations weight matrix in the Kalman filter. Recurrence algorithm of Kalman filtering can calculate and specify the weights during processing. However, the weights obtained in such way do not always exactly correspond to the actual observation accuracy. We established the observations weights based on the accuracy of baseline measurements. In the presented study, we offered and investigated different models of establishing the accuracy of the baselines. The offered models and the processing of the measured displacements were tested on an experimentally geodetic GNSS network. The research results show that despite of different weight models, changing weights up to 2 times do not change Kalman filtering accuracy extremely. The significant improvements for Kalman filtering accuracy for baselines shorter than 10 km were not got. Therefore, for typical GNSS monitoring networks with baseline range 10-15 km, we recommend to use any kind of models. The compulsory condition for getting correct and reliable results is checking results on blunders. For baselines, which are longer than 15 km we propose to use weight model which include baseline standard deviation from network adjustment and corrections for baseline length and its accuracy. | Roman Shults Andriy Annenkov | 2018 | Geodesy and Geodynamics2018，9，3： | 2 |
| 15 | Bayesian modeling of joint and conditional distributions显示文摘 | Andriy Norets Justinas Pelenis | 2012 | Journal of Econometrics2012，168，： | 1 |
| 16 | The effect of laser surface texturing on transitions in lubrication regimes during unidirectional sliding contact 显示文摘 | Andriy Kovalchenko Oyelayo Ajayi Ali Erdernir George Fenske Izhak Etsion | 2005 | Tribology International2005，38，： | 1 |
| 17 | Casp6 data processing and automatic evaluation at the protein structure prediction center显示文摘 | Andriy Kryshtafovych Maciej Milostan Lukasz Szajkowski | 2005 | Proteins: Structure Function and Bioinformatics2005，2005，7： | 1 |
| 18 | Terahertz inverse synthetic aperture radar (ISAR) imaging with a quantum cascade laser transmitter显示文摘 | Andriy A D Thomas M G Waldman J | 2010 | Optics Express2010，18，16： | 1 |
| 19 | 基于JPDF方法的喷雾湍流燃烧数值模拟显示文摘将速度-标量-频率联合概率密度函数JPDF输运方程方法应用于两相喷雾湍流反应流问题,利用火焰面模型解耦流动和化学反应动力学的耦合关系,建立相应的数值计算模型。采用Monte-Carlo数值计算方法,针对文献中以甲醇为燃料所进行的湍流喷雾燃烧值班火焰这一试验进行了数值模拟,通过与Fluent下的计算结果及试验结果的对比分析,验证了所建模型的准确性。 | 何志霞 王谦 Andriy Rybakov Ulrich Maas | 2010 | 农业机械学报2010，41，7： | 1 |
| 20 | Modeling Uncertainty of Induced Technological Change显示文摘 | Nebojsa Nakicenovic | 2000 | Energy Policy2000，，28： | 1 |
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