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| 1 | Non-alcoholic fatty liver disease and the metabolic syndrome:An update显示文摘Sedentary lifestyle and poor dietary choices are leading to a weight gain epidemic in westernized countries, subsequently increasing the risk for developing the metabolic syndrome and nonalcoholic fatty liver disease (NAFLD). NAFLD is estimated to affect approximate 30% of the general US population and is considered the hepatic manifestation of the metabolic syndrome. Recent findings linking the components of the metabolic syndrome with NAFLD and the progression to nonalcoholic steatohepatitis (NASH) will be reviewed; in particular, the role of visceral adipose tissue, insulin resistance, and adipocytokines in the exacerbation of these conditions. While no therapy has been proven effective for treating NAFLD/NASH, common recommendations will be discussed. | R Scott Rector John P Thyfault Yongzhong Wei Jamal A Ibdah | 2008 | World Journal of Gastroenterology2008,14,2: | 60 |
| 2 | Nonalcoholic fatty liver disease and mitochondrial dysfunction显示文摘Nonalcoholic fatty liver disease (NAFLD) includes hepatic steatosis, nonalcoholic steatohepatitis (NASH), fibrosis, and cirrhosis. NAFLD is the most common liver disorder in the United States and worldwide. Due to the rapid rise of the metabolic syndrome, the prevalence of NAFLD has recently dramatically increased and will continue to increase. NAFLD has also the potential to progress to hepatocellular carcinoma (HCC) or liver failure. NAFLD is strongly linked to caloric overconsumption, physical inactivity, insulin resistance and genetic factors. Although significant progress in understanding the pathogenesis of NAFLD has been achieved in years, the primary metabolic abnormalities leading to lipid accumulation within hepatocytes has remained poorly understood. Mitochondria are critical metabolic organelles serving as 'cellular power plants'. Accumulating evidence indicate that hepatic mitochondrial dysfunction is crucial to the pathogenesis of NAFLD. This review is focused on the significant role of mitochondria in the development of NAFLD. | Yongzhong Wei R Scott Rector John P Thyfault Jamal A Ibdah | 2008 | World Journal of Gastroenterology2008,14,2: | 32 |
| 3 | Effects of different brush border membrane vesicle isolation protocols on proteomic analysis of Cry1Ac binding proteins from the midgut of Helicoverpa armigera显示文摘从昆虫孤立的刷子边阶膜泡(BBMV ) 中间的勇气广泛地被用来学习 Cry1A 绑定蛋白质。样品准备在二维的电气泳动(2-DE ) 是重要的在 Helicoverpa 有佩带徽章权利的人决定一个合适的 BBMV 准备方法一因为 2-DE,我们比较了主要在钠 dodecyl sulfate-polyacrylamide 胶化电气泳动(SDS 页) 使用的三个出版 BBMV 准备方法。所有方法产出有约束力的蛋白质的类似的类型和数字,但是在不同数量。Abdul-Rauf 和 Ellar 协议是最好三,但是有的限制。足够的蛋白质数量为包含昆虫的有限数字的研究是重要的,例如到这个领域里的杆菌 thuringiensis 的昆虫抵抗的研究。因而,我们综合三个 BBMV 隔离方法进从 H 产出 BBMV 蛋白质的高数量的一个单个协议。有佩带徽章权利的人一幼虫的中间的勇气,它对 2-DE 分析证明合适。 | Li-Zhen Chen Ge-Mei Liang Brian G. Rector Jie Zhang Kong-Ming Wu Yu-Yuan Guo | 2008 | Insect Science2008,15,6: | 3 |
| 4 | All-cause hospitalizations for inflammatory bowel diseases:Can the reason for admission provide information on inpatient resource use?A study from a large veteran affairs hospital显示文摘Background:Inflammatory bowel diseases(IBDs) are group of chronic inflammatory illnesses with a remitting and relapsing course that may result in appreciable morbidity and high medical costs secondary to repeated hospitalizations.The study's objectives were to identify the reasons for hospitalization among patients with IBDs,and compare inpatient courses and readmission rates for IBD-related admissions versus non-IBD-related admissions.Methods:A retrospective chart review was performed on all patients with IBD admitted to the Minneapolis Veterans Affairs(VA) Medical Center between September 2010 and September 2012.Results:A total of 111 patients with IBD were admitted during the 2-year study period.IBD flares/complications accounted for 36.9% of the index admissions.Atherothrombotic events comprised the second most common cause of admissions(14.4%) in IBD patients.Patients with an index admission directly related to IBD were significantly younger and had developed IBD more recently.Unsurprisingly,the IBD admission group had significantly more gastrointestinal endoscopies and abdominal surgeries,and was more likely to be started on medication for IBD during the index stay.The median length of stay(LOS) for the index hospitalization for an IBD flare or complication was 4(2–8) days compared with 2(1–4) days for the other patients(P=0.001).A smaller percentage of the group admitted for an IBD flare/complication had a shorter ICU stay compared with the other patients(9.8% vs.15.7%,respectively); however,their ICU LOSs tended to be longer(4.5 vs.2.0 days,respectively,P=0.17).Compared to the other admission types,an insignificantly greater percentage of the group whose index admission was related to an IBD flare or complication had at least one readmission within 6 months of discharge(29% versus 21%; P=0.35).The rate of admission was approximately 80% greater in the group whose index admission was related to an IBD flare or complication compared to the other types of admission(rate ratio 1.8,95% confidence interval 0.96 to 3.4),although this difference did not reach statistical significance(P=0.07).Conclusion:Identifying the reasons for the patients' index admission,IBD flares versus all other causes,may provide valuable information concerning admission care and the subsequent admission history. | Ashish Malhotra K.C.Mandip Aasma Shaukat Thomas Rector | 2016 | Journal of Medical Colleges of PLA(China)2016,31,3: | 2 |
| 5 | The role of angiotensin II in nonalcoholic steatohepatitis显示文摘 | E. Matthew Morris Justin A. Fletcher John P. Thyfault R. Scott Rector | 2012 | Molecular and Cellular Endocrinology2012,,: | 2 |
| 6 | Building the Internet of Things Using RFID: The RFID Ecosystem Experience显示文摘 | Welbourne Evan Battle Leilani Cole Garret Gould Kayla Rector Kyle Raymer Samuel Balazinska Magdalena Borriello Gaetano | 2009 | IEEE Internet Computing2009,,3: | 2 |
| 7 | Management of hyperglycemia, dyslipidemia and albuminuria显示文摘 | Slinin Y Ishani A Rector T | 2012 | Kidney Dis2012,60,5: | 1 |
| 8 | Prognostic value of baselineplasma amino-terminal pro-brain natriuretic peptide and itsinteractions with irbesartan treatment effects in patients with heartfailure and preserved ejection fraction: findings from theI-PRESERVE trial显示文摘 | Anand IS Rector TS Cleland JG | 2011 | Circ Heart Fail2011,4,5: | 1 |
| 9 | 显示文摘 | Griessen R Rector J H | 1996 | Nature1996,380,: | 1 |
| 10 | Cognitive behavioral therapy forschizophrenia:An empirical review显示文摘 | Rector Neil A Beck Aaron T | 2012 | Journal of Nervous&Men-tal Disease2012,200,10: | 1 |
| 11 | Patients' self-assessment of their con- gestive heart failure显示文摘 | Rector TS Kubo S Cohn JN | 1987 | Heart Failure1987,3,: | 1 |
| 12 | Mechanisms for linezolid-induced anemia and thrombocytopenia显示文摘 | Bernstein WB Trotta RF Rector JT | | 0,,: | 1 |
| 13 | Elevated skeletal muscle irisin precursor FNDC5 mRNA in obese OLETF rats显示文摘 | Michael D. Roberts David S. Bayless Joseph M. Company Nathan T. Jenkins Jaume Padilla Thomas E. Childs Jeffrey S. Martin Vincent J. Dalbo Frank W. Booth R. Scott Rector M. Harold Laughlin | 2013 | Metabolism2013,,8: | 1 |
| 14 | Exercise and diet induced weight loss improves measures of oxidative stress and insulin sensitivity in adults with characteristics of the metabolic syndrome显示文摘 | RECTOR R S WARNER 8 O LIU Y | 2007 | Am J Physiol Endocrinol Metab2007,293,2: | 1 |
| 15 | The use of drill bit energy as a downhole seismic source 显示文摘 | Rector J W Marion B P | 1991 | Geophysics1991,56,5: | 1 |
| 16 | Post-event processing in social anxie- ty disorder: Idiosyncratic priming in the course of CBT 显示文摘 | Kocovski NL Rector NA | 2008 | Cognit Ther Res2008,32,1: | 1 |
| 17 | Anemia aud change in hemo-globin over time related to mortality and morbidity in patients with chronic heart thiture: results from VaI-HeRT 显示文摘 | Anand IS Kuskowski MA Rector TS | 2005 | Circulation2005,112,8: | 1 |
| 18 | Endogenous and silencing associated small RNAs in plants 显示文摘 | LLAVE C KASSCHAU K D RECTOR M A | 2002 | Plant Cell2002,14,7: | 1 |
| 19 | Coronary revascularization in insulin-dependent diabetic patients with chronic renal failure 显示文摘 | Manske CL Wang Y Rector T | 1992 | Lancet1992,340,8826: | 1 |
| 20 | Baseline and serial measurements of galectin-3 in patients with heart failure:relationship to prognosis and effect of treatment with valsartan in the Val-HeFT显示文摘 | Anand IS Rector TS Kuskowski M | | 0,,05: | 1 |