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| 1 | 石英ESR测年信号衰退特征研究进展显示文摘电子自旋共振(ESR)测年法是第四纪地质年代学的重要测试方法之一,其测年范围广,特别是对于20万年至百万年尺度的第四纪样品有着重要意义。准确测量古剂量是影响ESR测年法精度和可信度的重要因素之一,而掌握ESR信号衰退特征及机制是获得准确、可信古剂量的重要前提。ESR测年法适用的地质样品种类较多,如热液石英脉、地质断层泥、水系沉积物等,不同样品的ESR信号衰退特征和机制有较大差异。近年来,国内外学者针对不同地质样品中石英ESR信号的衰退特征和机制深入开展了一系列的实验室模拟和野外观测研究,取得了诸多新认识。回顾了近年来在石英ESR信号衰退特征领域取得的进展,特别是水系沉积物石英ESR信号的衰退特征,并展望了这一领域的未来工作重点。 | 刘春茹 尹功明 Rainer Grün | 2013 | 地球科学进展2013，28，1： | 17 |
| 2 | Climate Change, Risk and Grain Yields in China显示文摘Adopting Just and Pope (1978, 1979) style yield functions, this paper proposes a method to analyze the impacts of regional climate change on grain production in China. We find that changes in climate will affect grain production in North and South China differently. Specifically, it emerges that a 1℃ increase in annual average temperature could reduce national grain output by 1.45% (1.74% reduction in North China and 1.19% reduction in South China), while an increase in total annual precipitation of around 100 mm could increase national grain output by 1.31% (3.0% increase in North China and 0.59% reduction in South China). | Rainer Holst Xiaohua Yu Carola Grün | 2013 | Journal of Integrative Agriculture2013，12，7： | 14 |
| 3 | Serotonin type 3 receptor subunit gene polymorphisms associated with psychosomatic symptoms in irritable bowel syndrome:A multicenter retrospective study显示文摘BACKGROUND Single-nucleotide polymorphisms(SNPs)of the serotonin type 3 receptor subunit(HTR3)genes have been associated with psychosomatic symptoms,but it is not clear whether these associations exist in irritable bowel syndrome(IBS).AIM To assess the association of HTR3 polymorphisms with depressive,anxiety,and somatization symptoms in individuals with IBS.METHODS In this retrospective study,623 participants with IBS were recruited from five specialty centers in Germany,Sweden,the United States,the United Kingdom,and Ireland.Depressive,anxiety,and somatization symptoms and sociodemographic characteristics were collected.Four functional SNPs—HTR3A c.-42C>T,HTR3B c.386A>C,HTR3C c.489C>A,and HTR3E c.*76G>A—were genotyped and analyzed using the dominant and recessive models.We also performed separate analyses for sex and IBS subtypes.SNP scores were calculated as the number of minor alleles of the SNPs above.The impact of HTR3C c.489C>A was tested by radioligand-binding and calcium influx assays.RESULTS Depressive and anxiety symptoms significantly worsened with increasing numbers of minor HTR3C c.489C>A alleles in the dominant model(F_(depressive)=7.475,P_(depressive)=0.006;F_(anxiety)=6.535,P_(anxiety)=0.011).A higher SNP score(range 0-6)was linked to a worsened depressive symptoms score(F=7.710,P-linear trend=0.006)in IBS.The potential relevance of the HTR3C SNP was corroborated,showing changes in the expression level of 5-HT3AC variant receptors.CONCLUSION We have provided the first evidence that HTR3C c.489C>A is involved in depressive and anxiety symptoms in individuals with IBS.The SNP score indicated that an increasing number of minor alleles is linked to the worsening of depressive symptoms in IBS. | Sabrina Berens Yuanjun Dong Nikola Fritz Jutta Walstab Mauro D'Amato Tenghao Zheng Verena Wahl Felix Boekstegers Justo Lorenzo Bermejo Cristina Martinez Stefanie Schmitteckert Egbert Clevers Felicitas Engel Annika Gauss Wolfgang Herzog Robin Spiller Miriam Goebel-Stengel Hubert Mönnikes Viola Andresen Frieling Thomas Jutta Keller Christian Pehl Christoph Stein-Thöringer Gerard Clarke Timothy G Dinan Eamonn M Quigley Gregory Sayuk Magnus Simrén Jonas Tesarz Gudrun Rappold Lukas van Oudenhove Rainer Schaefert Beate Niesler | 2022 | World Journal of Gastroenterology2022，28，21： | 2 |
| 4 | The influence of EDDS on the uptake of heavy metal in hydroponically grown sunflowers显示文摘 | Susan T Rainer S Bemd N | 2006 | Chemosphere2006，62，： | 1 |
| 5 | Trust in software outsourcing relationships:An empirical investigation of Indian software compa-nies显示文摘 | OZA N V HALLT RAINER A | | 0，，05： | 1 |
| 6 | Trust in software outsourcing relationships: An empirical investiga- tion of Indian software eompanies显示文摘 | Oza N V Hall T Rainer A | 2006 | Information and Software Technology2006，48，1： | 1 |
| 7 | Stimulation of TNF receptor type 2 expands regulatory T cells and ameliorates established collagen-induced arthritis in mice显示文摘Tumor necrosis factor(TNF)and its receptors TNF receptor type 1(TNFR1)and type 2(TNFR2)have a central role in chronic inflammatory diseases.While TNFR1 mainly confers inflammation,activation of TNFR2 elicits not only pro-inflammatory but also anti-inflammatory effects.In this study,we wanted to investigate the anti-inflammatory therapeutic potential of selective activation of TNFR2 in mice with established collageninduced arthritis.Mice with established arthritis induced by immunization with bovine collagen type II were treated with six injections of the TNFR2-specific agonist TNCscTNF80,given every second day.Two days after treatment cessation,the cell compositions of bone marrow,spleen and lymph nodes were analyzed.Mice were visually scored until day 30 after the start of therapy and the degree of joint inflammation was determined by histology.Treatment with TNCscTNF80 increased arthritis-induced myelopoiesis.Little effect was seen on the infiltration rate of inflammatory immature myeloid cells and on the reduction of lymphoid cells in secondary lymphoid organs.Upon treatment,frequency of regulatory T(Treg)cells in the CD4+T-cell population was increased in both spleen and inguinal lymph nodes.In addition,the expression of TNFR2 on Treg cells was enhanced.The clinical score started to improve 1 week after cessation treatment and remained lower 30 days after initiation of therapy.The histological score also revealed amelioration of joint inflammation in TNCscTNF80-treated versus control mice.Activation of TNFR2 might provide a suitable therapeutic strategy in autoimmune arthritis by increasing the numbers of regulatory cell types,in particular Treg cells,and by attenuation of arthritis. | Vanessa Lamontain Tobias Schmid Dorothea Weber-Steffens David Zeller Zsuzsa Jenei-Lanzl Harald Wajant Rainer H Straub Daniela N Männel | 2019 | Cellular & Molecular Immunology2019，16，1： | 1 |
| 8 | Value of serum procalcitonin, neopterin, and C-reactive Protein in differentiating bacterial from viral etiolo-gies in patients presenting with Lower respiratory tract infections显示文摘 | IP M Rainer TH Lee N | 2007 | Diagn Microbiol Infect Dis2007，59，2： | 1 |
| 9 | Trace element speciation in combustion processes--Review and compilations of thermodynamic data显示文摘 | Karin L Anders N Rainer B | 2007 | Fuel Processing Technology2007，88，1112： | 1 |
| 10 | EDTA is a better anticoagulant than heparin or citrate for delayed blood processing for plasma DNA analysis显示文摘 | Lam N Y Rainer T H Chiu R W Lo Y M | 2004 | Clin Chem2004，50，： | 1 |
| 11 | 64-slice multidetector coronary CT angiography: in vitro evaluation of 68 different stents显示文摘 | David Maintz Harald Seifarth Rainer Raupach Thomas Flohr Michael Rink Torsten Sommer Murat ?zgün Walter Heindel Roman Fischbach | 2006 | European Radiology2006，，4： | 1 |
| 12 | Matrix-free and material-enhanced laser desorption/ionization mass spectrometry for the analysis of low molecular weight compounds显示文摘 | RAINER M QURESHI M N BONN G K | 2011 | Analytical and Bioanalytical Chemistry2011，400，8： | 1 |
| 13 | Trust in software outsourcing relationships: An empirical investigation of Indian software companies显示文摘 | Oza N V Hall T Rainer A Grey S G | 2006 | Information and Software Technology2006，48，5： | 1 |
| 14 | The epidemiology of myelodysplastic syndromes显示文摘 | Ulrich G Judith N Rainer H | 2008 | Clinical Leukemia2008，2，1： | 1 |
| 15 | RAC-3 is a NF-kB coactivator显示文摘 | Santiago W Ignacio N Rainer L | 2000 | FEBS Letters2000，485，： | 1 |
| 16 | Advanced virtual corrective osteotomy显示文摘 | Andre N Katja B Rainer W | 2005 | International Congress Series2005，1281，： | 1 |
| 17 | Value of serum procalcitonin, neopterin, and C-reactive protein in differ- erniating bacterial from viral etiologies in patients presenting with lower respiratory tract infection 显示文摘 | Margaret IP Rainer TH Lee N | 2007 | Diagn Microbiol Infect Dis2007，59，2： | 1 |
| 18 | Controlling persistent organic pollutants–what next? 1 Correspondence to: Nicole G Weavers, ETAF, European Training and Assessment Foundation, PO Box 182, 6700 AD, Wageningen, The Netherlands. Tel.: +31-317-484924; Fax: +31-317-484941 1显示文摘 | Harry W. Vallack Dick J. Bakker Ingvar Brandt Eva Brostr?m-Lundén Abraham Brouwer Keith R. Bull Clair Gough Ramon Guardans Ivan Holoubek Bo Jansson Rainer Koch Johan Kuylenstierna André Lecloux Donald Mackay Patrick McCutcheon Paolo Mocarelli Rob D.F. Taa | 1998 | Environmental Toxicology and Pharmacology1998，，3： | 1 |
| 19 | Value of serum procalcitonin,neopterin,and C-reactive protein in differentiating bacterial from viral etiologies in patients presenting with lower respiratory tract infections显示文摘 | Margaret IP Rainer TH Lee N | | 0，，02： | 1 |
| 20 | Angiopoietin-1 mediates inhibition of hypertension-induced release of angiopoietin-2from endothelial cells显示文摘 | Thomas K Evelyn E Rainer N | 2012 | Cardiovascular Research2012，94，3： | 1 |
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