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| 1 | Reduced striatal volumes in Parkinson’s disease:a magnetic resonance imaging study显示文摘Background:The presence and extent of structural changes in the brain as a consequence of Parkinson’s disease(PD)is still poorly understood.Methods:High-resolution 3-tesla T1-weighted structural magnetic resonance images in sixty-five PD and 27 age-matched healthy control participants were examined.Putamen,caudate,and intracranial volumes were manually traced in the axial plane of 3D reconstructed images.Striatal nuclei volumes were normalized to intracranial volume for statistical comparison.Disease status was assessed using the Unified Parkinson’s Disease Rating Scale and Hoehn and Yahr scale.Cognitive status was assessed using global status tests and detailed neuropsychological testing.Results:Both caudate and putamen volumes were smaller in PD brains compared to controls after adjusting for age and gender.Caudate volumes were reduced by 11%(p=0.001)and putamen volumes by 8.1%(p=0.025).PD striatal volumes were not found to be significantly correlated with cognitive or motor decline.Conclusion:Small,but significant reductions in the volume of both the caudate and putamen occur in PD brains.These reductions are independent of the effects of age and gender,however the relation of these reductions to the functional loss of dopamine,which is characteristic of PD,remains unclear. | Toni L Pitcher Tracy R Melzer Michael R MacAskill Charlotte F Graham Leslie Livingston Ross J Keenan Richard Watts John C Dalrymple-Alford Tim J Anderson | 2012 | Translational Neurodegeneration2012，1，1： | 2 |
| 2 | Immunogenicity of outer membrane components of Haemophilus ( Actinobacillus ) pleuropleumoniae 显示文摘 | Rapp V J Ross R F | 1988 | Can Vet J1988，29，： | 1 |
| 3 | Cloning of porcine NRAMP1 and its induction by lipopolysaccharide,tumor necrosis factor alpha,and interleukin-1beta:Role of CD14 and mitogen-activated protein kinases显示文摘 | Zhang G Wu H Ross C R Minton J E and Blecha F | | 0，，03： | 1 |
| 4 | Neurological evaluation of toxic axonopathies in rats: acrylamide and 2,5-hexanedione显示文摘 | LOPACHIN R M ROSS J F REID M L | 2002 | Neurotoxicology2002，23，1： | 1 |
| 5 | Chemoattractant properties of PR-39,a neutrophil antibacterial peptide显示文摘 | Huang H J Ross C R Blecha F | 1997 | Leukoc Biol1997，61，： | 1 |
| 6 | Diameter of involved nerves predicts outcomes in cutaneous squamous cell carcinoma with perineural invasion: an investigator-blinded retrospective cohort study显示文摘 | ROSS A S WHALEN F M ELENITSAS R | 2009 | Dermatoi Surg2009，35，12： | 1 |
| 7 | Surface-enhanced Infrared Spectroscopy 显示文摘 | Aroca R F Ross D J Domingo C | 2004 | Appl Spectrosc2004，58，： | 1 |
| 8 | Coarsening of self-assembled Ge quantum dots on Si (001) 显示文摘 | Ross F M Tersoff J Tromp R M | 1998 | Phys Rev Lett1998，80，5： | 1 |
| 9 | Impact: a platform for collaborating agents 显示文摘 | Aresha K A Ozcan F Ross R | 1999 | IEEE Intelligent Systems1999，14，2： | 1 |
| 10 | The major genetic determinants of HIV-1control affect HLA class I peptide presentation显示文摘 | International HIV Controllers Study Pereyra F Jia X McLaren P J Telenti A de Bakker P I Walker B D Ripke S Brumme C J Pulit S L Carrington M Kadie C M Carlson J M Heckerman D Graham R R Plenge R M Deeks S G Gianniny L Crawford G Sullivan J Gonzalez E Davies L Camargo A Moore JM Beattie N Gupta S Crenshaw A Burtt N P Guiducci C Gupta N Gao X Qi Y Yuki Y Piechocka-Trocha A Cutrell E Rosenberg R Moss K L Lemay P O'Leary J Schaefer T Verma P Toth I Block B Baker B Rothchild A Lian J Proudfoot J Alvino D M Vine S Addo M M Allen T M Altfeld M Henn M R Le Gall S Streeck H Haas D W Kuritzkes D R Robbins G K Shafer R W Gulick R M Shikuma C M Haubrich R Riddler S Sax P E Daar E S Ribaudo H J Agan B Agarwal S Ahern R L Allen B L Altidor S Altschuler E L Ambardar S Anastos K Anderson B Anderson V Andrady U Antoniskis D Bangsberg D Barbaro D Barrie W Bartczak J Barton S Basden P Basgoz N Bazner S Bellos N C Benson A M Berger J Bernard N F Bernard A M Birch C Bodner S J Bolan R K Boudreaux E T Bradley M Braun J F Brndjar J E Brown S J Brown K Brown S T Burack J Bush LM Cafaro V Campbell O Campbell J Carlson R H Carmichael J K Casey K K Cavacuiti C Celestin G Chambers S T Chez N Chirch L M Cimoch P J Cohen D Cohn LE Conway B Cooper D A Cornelson B Cox D T Cristofano M V Cuchural G Jr Czartoski J L Dahman J M Daly J S Davis B T Davis K Davod S M DeJesus E Dietz C A Dunham E Dunn M E Ellerin T B Eron J J Fangman J J Farel C E Ferlazzo H Fidler S Fleenor-Ford A Frankel R Freedberg K A French N K Fuchs JD Fuller J D Gaberman J Gallant J E Gandhi R T Garcia E Garmon D Gathe J C Jr Gaultier C R Gebre W Gilman F D Gilson I Goepfert P A Gottlieb M S Goulston C Groger R K Gurley T D Haber S Hardwicke R Hardy W D Harrigan P R Hawkins T N Heath S Hecht F M Henry W K Hladek M Hoffman R P Horton J M Hsu R K Huhn G D Hunt P Hupert M J Illeman M L Jaeger H Jellinger R M John M Johnson J A Johnson K L Johnson H Johnson K Joly J Jordan W C Kauffman C A Khanlou H Killian R K Kim A Y Kim D D Kinder C A Kirchner J T Kogelman L Kojic E M Korthuis P T Kurisu W Kwon D S LaMar M Lampiris H Lanzafame M Lederman M M Lee D M Lee J M Lee M J Lee E T Lemoine J Levy J A Llibre J M Liguori M A Little S J Liu A Y Lopez A J Loutfy M R Loy D Mohammed D Y Man A Mansour M K Marconi V C Markowitz M Marques R Martin J N Martin H L Jr Mayer K H McElrath M J McGhee T A McGovern B H McGowan K McIntyre D Mcleod GX Menezes P Mesa G Metroka CE Meyer-Olson D Miller A O Montgomery K Mounzer K C Nagami E H Nagin I Nahass R G Nelson M O Nielsen C Norene D L O'Connor D H Ojikutu B O Okulicz J Oladehin O O Oldfield E C Olender S A Ostrowski M Owen WF Jr Pae E Parsonnet J Pavlatos A M Perlmutter A M Pierce M N Pincus J M Pisani L Price L J Proia L Prokesch R C Pujet H C Ramgopal M Rathod A Rausch M Ravishankar J Rhame F S Richards C S Richman D D Rodes B Rodriguez M Rose R C 3rd Rosenberg E S Rosenthal D Ross P E Rubin D S Rumbaugh E Saenz L Salvaggio M R Sanchez WC Sanjana V M Santiago S Schmidt W Schuitemaker H Sestak P M Shalit P Shay W Shirvani V N Silebi V I Sizemore J M Jr Skolnik P R Sokol-Anderson M Sosman J M Stabile P Stapleton J T Starrett S Stein F Stellbrink H J Sterman FL Stone V E Stone D R Tambussi G Taplitz R A Tedaldi E M Telenti A Theisen W Torres R Tosiello L Tremblay C Tribble M A Trinh P D Tsao A Ueda P Vaccaro A Valadas E Vanig T J Vecino I Vega V M Veikley W Wade B H Walworth C Wanidworanun C Ward D J Warner D A Weber R D Webster D Weis S Wheeler D A White D J Wilkins E Winston A Wlodaver C G van't Wout A Wright D P Yang O O Yurdin D L Zabukovic B W Zachary K C Zeeman B Zhao M | 2010 | Science2010，330，6010： | 1 |
| 11 | Experimental constraints on the depth of olivine metastability in subducting lithosphere 显示文摘 | Mosenfelder J L Marton F C Ross C R | 2001 | Physics of the Earth and Planetary Interiors2001，127，： | 1 |
| 12 | Humoral and cellular immune responses of pigs inoculated with Mycoplasma hyopneumoniae 显示文摘 | MESSIER S ROSS R F PAUL P S | 1990 | Am J Vet Res1990，51，1： | 1 |
| 13 | Identification and characterization of a Mycoplasma hyopneumoniae adhesion显示文摘 | Zhang Q T Young Ross R F | 1995 | Infect Immun1995，63，： | 1 |
| 14 | Effect of ex situ treatments with SO2 on the activity of a low loading silver-alumina catalyst for the selective reduction of NO and NO2 by propene 显示文摘 | Meunier F C Ross J R H | 2000 | Appl Catal B2000，24，1： | 1 |
| 15 | Adherence of Myco?plasma hyopnemnoniae to cell monolayers显示文摘 | Zielinsli G C Young T Ross R F et a1 | 1990 | Am J Vet Res1990，51，3： | 1 |
| 16 | Geology and geothermal origin of Grant Canyon and Bacon Flat oil fields,Railroad Valley,Nevada显示文摘 | Hulen J B Goff F Ross J R | 1994 | AAPG Bulletin1994，78，3： | 1 |
| 17 | Adherence of Mycoplasma hyopneu?moniae to porcine ciliated respiratory tract cells显示文摘 | Zielinski G C T Ross R F | 1993 | Am J Vet Res1993，54，8： | 1 |
| 18 | Pharmacokinetics of remifentanil in anesthe tized pediatric patients undergoing elective surgery or diagnostic procedures显示文摘 | Ross A K Davis P J Dear Gd G L Ginsberg B McGowan F X Stiller R D | 2001 | Anesth Analg2001，93，： | 1 |
| 19 | Knowledge management in research and development显示文摘 | Armbrencht Jr Ross F M Chapas R B | 2001 | Research Technology Management2001，44，4： | 1 |
| 20 | Evaluation of the ELISA and comparison to the complement fixation test and radial immunodiffusion enzyme assay for detection of antibodies against Mycoplasma hyopneumoniae in swine serum 显示文摘 | Bereiter M Young T F Joo H S Ross R F | 1990 | Vet Microbiol1990，25，23： | 1 |
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