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| 1 | Factors affecting healing after arthroscopic rotator cuff repair显示文摘Rotator cuff repair has been shown to have good longterm results. Unfortunately, a significant proportion of repairs still fail to heal. Many factors, both patient and surgeon related, can influence healing after repair. Older age, larger tear size, worse muscle quality, greater muscle-tendon unit retraction, smoking, osteoporosis, diabetes and hypercholesterolemia have all shown to negatively influence tendon healing. Surgeon related factors that can influence healing include repair construct-single vs double row, rehabilitation, and biologics including platelet rich plasma and mesenchymalstem cells. Double-row repairs are biomechanically stronger and have better healing rates compared with single-row repairs although clinical outcomes are equivalent between both constructs. Slower, less aggressive rehabilitation programs have demonstrated improved healing with no negative effect on final range of motion and are therefore recommended after repair of most full thickness tears. Additionally no definitive evidence supports the use of platelet rich plasma or mesenchymal stem cells regarding improvement of healing rates and clinical outcomes. Further research is needed to identify effective biologically directed augmentations that will improve healing rates and clinical outcomes after rotator cuff repair. | Amir M Abtahi Erin K Granger Robert Z Tashjian | 2015 | World Journal of Orthopedics2015，6，2： | 16 |
| 2 | Advances in hepatocellular carcinoma: Nonalcoholic steatohepatitis-related hepatocellular carcinoma显示文摘An increase in the prevalence of obesity and diabetes mellitus has been associated with the rise in non-alcoholic fatty liver disease(NAFLD). Two-thirds of the obese and diabetic populations are estimated to develop NAFLD. Currently, NAFLD is the most common etiology for chronic liver disease globally. The clinical spectrum of NAFLD ranges from simple steatosis, an accumulation of fat greater than 5% of liver weight, to nonalcoholic steatohepatitis(NASH), a more aggressive form with necroinflammation and fibrosis. Among the patients who develop NASH, up to 20% may advance to cirrhosis and are at risk for complications of end-stage liver disease. One of the major complications observed in patients with NASH-related cirrhosis is hepatocellular carcinoma(HCC), which has emerged as the sixth most common cancer and second leading etiology of cancer-related deaths worldwide. The incidence of HCC in the United States alone has tripled over the last three decades. In addition, emerging data are suggesting that a small proportion of patients with NAFLD may be at higher risk for HCC in the absence of cirrhosis - implicating obesity and diabetes mellitus as potential risk factors for HCC. | Fauzia Z Khan Ryan B Perumpail Robert J Wong Aijaz Ahmed | 2015 | World Journal of Hepatology2015，7，18： | 10 |
| 3 | The metabolic syndrome显示文摘 | Robert H Eckel KGMM Alberti Scott M Grundy Paul Z Zimmet | 2010 | The Lancet2010，，9710： | 4 |
| 4 | The metabolic syndrome显示文摘 | Robert H Eckel Scott M Grundy Paul Z Zimmet | 2005 | The Lancet2005，，9468： | 2 |
| 5 | Functional outcomes assessment in shoulder surgery显示文摘The effective evaluation and management of orthopaedic conditions including shoulder disorders relies upon understanding the level of disability created by the disease process. Validated outcome measures are critical to the evaluation process. Traditionally, outcome measures have been physician derived objective evaluations including range of motion and radiologic evaluations. However, these measures can marginalize a patient's perception of their disability or outcome. As a result of these limitations, patient self-reported outcomes measures have become popular over the last quarter century and are currently primary tools to evaluate outcomes of treatment. Patient reported outcomes measures can be general health related quality of life measures, health utility measures, region specific health related quality of life measures or condition specific measures. Several patients self-reported outcomes measures have been developed and validated for evaluating patients with shoulder disorders. Computer adaptive testing will likely play an important role in the arsenal of measures used to evaluate shoulder patients in the future. The purpose of this article is to review the general health related quality-of-life measures as well as the jointspecific and condition specific measures utilized in evaluating patients with shoulder conditions. Advancesin computer adaptive testing as it relates to assessing dysfunction in shoulder conditions will also be reviewed. | James D Wylie James T Beckmann Erin Granger Robert Z Tashjian | 2014 | World Journal of Orthopedics2014，5，5： | 2 |
| 6 | The metabolic syndrome显示文摘 | Robert H Eckel KGMM Alberti Scott M Grundy Paul Z Zimmet | 2010 | 2010 (9710)2010，，9710： | 2 |
| 7 | SARS-COV-2 infection(coronavirus disease 2019)for the gastrointestinal consultant显示文摘The current pandemic due to the severe acute respiratory syndrome coronavirus 2 has caused an extreme burden for health care systems globally,and the number of cases is expected to continue to increase,at least in the immediate future.The virus is estimated to have infected more than 1.5 million individuals.The available reports suggest that gastrointestinal(GI)involvement in coronavirus disease 2019(COVID-19)is common and in some cases the GI symptoms may precede the respiratory symptoms.In addition to direct effects of severe acute respiratory syndrome coronavirus 2,the infected patients remain at risk for the complications commonly managed by gastroenterology and hepatology consultants.The most commonly reported GI manifestation of COVID-19 is diarrhea,which is reported in a third to up to more than half of the patients.Mild to moderate elevation of the liver enzymes are also common,although no case of acute liver failure has been reported so far.Many of the medications used for treatment of COVID-19 can also be associated with GI symptoms or liver injury and can be included in the differential diagnosis in these patients.Although the diagnosis of the infection is currently based on RNA analysis in respiratory samples,the available literature on fecal shedding of this virus suggests that fecal RNA testing might prove to be a useful diagnostic test.It is reasonable to delay all non-urgent endoscopic procedures during the peak of the pandemic and use additional protective equipment such as N95 respirators during endoscopy while most patients can be considered high risk for having been exposed to the virus. | Kaveh Hajifathalian Srihari Mahadev Robert E Schwartz Shawn Shah Kartik Sampath Felice Schnoll-Sussman Robert S Brown Jr David Carr-Locke David E Cohen Reem Z Sharaiha | 2020 | World Journal of Gastroenterology2020，26，14： | 2 |
| 8 | On parameter identifiability of MIMO radar 显示文摘 | Li J Stoica P Xu L Z Roberts W | 2007 | IEEE Signal Processing Letters2007，14，12： | 1 |
| 9 | Last interglacial age for aeolian and ma- rine deposits and the Nahoon fossil human footprints, South- east Coast of South Africa 显示文摘 | Jacobs Z Roberts D L | 2009 | Quaternary Geochronology2009，4，2： | 1 |
| 10 | Facies Associations,Pa-leoenvironment, and Base-Level Changes in the Up-per Cretaceous Wahweap Formation, Utah, USA显示文摘 | Jinnah Z A Roberts E M | 2011 | Journal of Sedimentary Research2011，81，： | 1 |
| 11 | Anti-Interleukin-17 Monoclonal Antibody Ixekizumab in Chronic Plaque Psoriasis显示文摘 | Craig L Robert M Claus Z | 2012 | N Engl J Med2012，366，： | 1 |
| 12 | The human ARHI tumor suppressor gene inhibits lactation and growth in transgenic mice 显示文摘 | Xu Fengji Xia Weiya Robert Z L | 2000 | Cancer Res2000，60，17： | 1 |
| 13 | Down regulation of miRNA-200c links breast cancer stem cells with normal stem cells显示文摘 | Yohei S Maider Z Robert W | 2009 | Cell2009，138，： | 1 |
| 14 | Enforced expression of EBF in hematopoietic stem cells restricts lymphopoiesis to the B cell lineage显示文摘 | Zheng Z Claudiu V C Robert P Stephan | 2003 | EMBO J2003，22，： | 1 |
| 15 | Rice P - ta gene confers resistance to the major pathotypes of the rice blast fungus in the United States 显示文摘 | Jia Y Wang Z Robert G | 2004 | Phytopathology2004，94，3： | 1 |
| 16 | Slug and Sox9 Cooperatively Determine the Mammary Stem Cell State显示文摘 | Wenjun Guo Zuzana Keckesova Joana Liu Donaher Tsukasa Shibue Verena Tischler Ferenc Reinhardt Shalev Itzkovitz Aurelia Noske Ursina Zürrer-H?rdi George Bell Wai Leong Tam Sendurai A. Mani Alexander van Oudenaarden Robert A. Weinberg | 2012 | Cell2012，，5： | 1 |
| 17 | Three biomarkera identified from serum proteomic analysis for the detection of early stage ovarian cancer显示文摘 | Zhang Z Robert C Song J | 2004 | Cancer Research2004，64，： | 1 |
| 18 | Survival factor-mediated Bad phosphorylation raises the mito-chondrial threshold for apoptsis显示文摘 | Sandeep Robert Datta Ann M Ranger Michael Z Lin | 2002 | Dev Cell2002，3，5： | 1 |
| 19 | DNA barcoding Australia's fish species显示文摘 | Robert D W Tyler S Z Bronwyn H I | 2005 | Philosophical Transactions of the Royal Socity B2005，360，1462： | 1 |
| 20 | The future of wind forecasting and utility operations显示文摘 | Mark A Lawrence J Robert Z | 2005 | IEEE Power Energy Magzine2005，6，3： | 1 |
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