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| 1 | 国际胃袖状切除专家共识:基于>12000手术病例的最佳操作指南显示文摘腹腔镜胃袖状切除术(1aparoscopic sleeve gastrectomy,LSG)系相对较新的减重手术方式。因其操作相对简单、治疗肥胖合并疾病及减重效果明显,逐步得以广泛接受。目前美国代谢与减重手术协会将其推荐为肥胖症治疗的单独标准术式。2011年3月25~26日, | 苏远涛 徐安安 朱江帆 Diaz AA Arvidsson D Baker RS Basso N Bellanger D Boza C El Mourad H France M Gagner M Galvao-Neto M Higa KD Himpens J Hutchinson CM Jacobs M Jorgensen JO Jossart G Lakdawala M Nguyen NT Nocca D Prager G Pomp A Ramos AC Rosenthal RJ Shah S Vix M Wittgrove A Zundel N | 2013 | 中国微创外科杂志2013，13，9： | 12 |
| 2 | Understanding plant drought resistance in a Mediterranean coastal sand dune ecosystem:differences between native and exotic invasive species显示文摘Aims Mediterranean coastal dunes are habitats of great conservation interest,with a distinctive and rich flora.In the last century,Acacia spp.,native from Australia,have been introduced in Portugal,with the objective of stabilizing sand dunes,and since have become dominant in numerous sand dune habitats.This invasion process led to the reduction of native plant species richness,changed soil characteristics and modified habitat’s microclimatic char-acteristics.The aim of this research was to typify and compare,in Mediterranean sand dune ecosystems,the ecophysiological responses to drought of Helichrysum italicum and Corema album,two native species,and Acacia longifolia,an exotic invasive spe-cies.We addressed the following specific objectives:(i)to com-pare water relations and water use efficiencies,(ii)to evaluate water stress,(iii)to assess water use strategies and water sources used by plants and(iv)to evaluate the morphological adaptations at leaf and phyllode level.Methods In order to obtain an integrative view of ecophysiological patterns,water relations and performance measuring methods have been applied:predawn(ψPD)and midday(ψMD)water potential,chloro-phyll a fluorescence,oxygen isotopic composition of xylem,rain and groundwater(δ18O)and leaf carbon isotopic discrimination(Δ13C).The leaf characteristics of the three species,as well as the histochemistry of non-glandular trichome cell walls,were also studied to identify morpho-traits related to drought resistance.Important Findings The results support our initial hypothesis:although A.longifolia clearly possesses a degree of resistance to water stress,such ability is provided by a different water strategy,when compared to native species.Natives relied on morphological adaptations to restrict water loss,whereas the invasive species adjusted the water uptake as a way to balance their limited ability of restricting water loss.We corroborate that woody native species(i)have a conservative water-saving strategy and minor seasonal variations relative to invasive species,(ii)use enriched water sources during drought periods,indicating different water sources and root systems com-paring with invasive species and(iii)present drought leaf morpho-functional adaptations related with limiting water loss.Comparing the physiological performance of invasive and native species can offer causal explanations for the relative success of alien plant invasions on sand dunes ecosystems. | Cristina Antunes Ana Júlia Pereira Patrícia Fernandes Margarida Ramos Lia Ascensão Otília Correia Cristina Máguas | 2018 | Journal of Plant Ecology2018，11，1： | 4 |
| 3 | Quality of life, work productivity impairment and healthcare resources in inflammatory bowel diseases in Brazil显示文摘BACKGROUND Inflammatory bowel diseases(IBD)have been associated with a low quality of life(QoL)and a negative impact on work productivity compared to the general population.Information about disease control,patient-reported outcomes(PROs),treatment patterns and use of healthcare resources is relevant to optimizing IBD management.AIM To describe QoL and work productivity and activity impairment(WPAI),treatment patterns and use of healthcare resources among IBD patients in Brazil.METHODS A multicenter cross-sectional study included adult outpatients who were previously diagnosed with moderate to severe Crohn’s disease(CD)or ulcerative colitis(UC).At enrolment,active CD and UC were defined as having a Harvey Bradshaw Index≥8 or a CD Activity Index≥220 or calprotectin>200μg/g or previous colonoscopy results suggestive of inadequate control(per investigator criteria)and a 9-point partial Mayo score≥5,respectively.The PRO assessment included the QoL questionnaires SF-36 and EQ-5D-5L,the Inflammatory Bowel Disease Questionnaire(IBDQ),and the WPAI questionnaire.Information about healthcare resources and treatment during the previous 3 years was collected from medical records.Chi-square,Fisher’s exact and Student’s t-/Mann-Whitney U tests were used to compare PROs,treatment patterns and the use of healthcare resources by disease activity(α=0.05).RESULTS Of the 407 patients in this study(CD/UC:64.9%/35.1%,mean age 42.9/45.9 years,54.2%/56.6%female,38.3%/37.1%employed),44.7%/25.2%presented moderate-to-severe CD/UC activity,respectively,at baseline.Expressed in median values for CD/UC,respectively,the SF-36 physical component was 46.6/44.7 and the mental component was 45.2/44.2,the EQ-visual analog scale score was 80.0/70.0,and the IBDQ overall score was 164.0/165.0.Moderate to severe activity,female gender,being unemployed,a lower educational level and lower income were associated with lower QoL(P<0.05).Median work productivity impairment was 20%and 5%for CD and UC patients,respectively,and activity impairment was 30%,the latter being higher among patients with moderate to severe disease activity compared to patients with mild or no disease activity(75.0%vs 10.0%,P<0.001).For CD/UC patients,respectively,25.4%/2.8%had at least one surgery,38.3%/19.6%were hospitalized,and 70.7%/77.6%changed IBD treatment at least once during the last 3 years.The most common treatments at baseline were biologics(75.3%)and immunosuppressants(70.9%)for CD patients and 5-ASA compounds(77.5%)for UC patients.CONCLUSION Moderate to severe IBD activity,especially among CD patients,is associated with a substantial impact on QoL,work productivity impairment and an increased number of IBD surgeries and hospitalizations in Brazil. | Rogerio Serafim Parra Julio MF Chebli Heda MBS Amarante Cristina Flores Jose ML Parente Odery Ramos Milene Fernandes Jose JR Rocha Marley R Feitosa Omar Feres Antonio S Scotton Rodrigo B Nones Murilo M Lima Cyrla Zaltman Carolina D Goncalves Isabella M Guimaraes Genoile O Santana Ligia Y Sassaki Rogerio S Hossne Mauro Bafutto Roberto LK Junior Mikaell AG Faria Sender J Miszputen Tarcia NF Gomes Wilson R Catapani Anderson A Faria Stella CS Souza Rosana F Caratin Juliana T Senra Maria LA Ferrari | 2019 | World Journal of Gastroenterology2019，25，38： | 2 |
| 4 | Sequential extraction of copper, lead, cadmium and zinc in sediments from Ebro River (Spain): relationship with levels detected in earthworms 显示文摘 | RAMOS L GONZALEZ M J HERN ~NDEZ L M | 1999 | Bulletin of Environment Contamination and Toxicology1999，62，： | 1 |
| 5 | Determination of the furaltadone metabolite 5-methylmorpholino-3-amino -9 oxazolidinone (AMOZ) using liquid chromatography coupled to electrospray tandem mass spectrometry during the nitrofuran crisis in Portugal显示文摘 | Barbosa J Ferreira M L Ramos F | 2007 | Accred Qual Assur2007，12，： | 1 |
| 6 | Substance P up-regulates matrix metalloproteinase-1 and down-regulates collagen in human lung fibroblast显示文摘 | Ramos C Montano M Cisneros J | 2007 | Exp Lung Res2007，33，34： | 1 |
| 7 | 显示文摘 | CALZDA M L MARTIN M J RAMOS P | 1997 | J Phys Chem Solids1997，58，7： | 1 |
| 8 | Optimization of millimeter-wave signal generation through FM-IM conversion in chirped fiber gratings 显示文摘 | Marti J Fuster J M Ramos F | 2000 | Microwave and Optical Technology Letters2000，27，6： | 1 |
| 9 | Bioaccumulation and toxicity of hexachlorobenzene in Chlorella vulgaris and Daphnia magna 显示文摘 | Munoz J M Ramos C Tarazona J V | 1996 | Aquatic Toxicology1996，35，34： | 1 |
| 10 | Sequential Automated Focused Microwave-Assisted Soxhlet Extraction of Compounds with Different Polarity from Marine Sediments Prior to Gas Chromato-graphy Mass Spectrometry Detection显示文摘 | MORALES-MUNOZS LUQUE-GARCaA J L RAMOS M J | 2005 | Chromatographia2005，62，： | 1 |
| 11 | A low-complexity space-time RAKE receiver for DS-CDMA communica- tions 显示文摘 | Ramos J Zoltowski M D Liu Hui | 1997 | IEEE Signal Processing Letters1997，4，9： | 1 |
| 12 | CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients显示文摘 | Savoldo Barbara Ramos Carlos Almeida Liu Enli Mims Martha P Keating Michael J Carrum George Kamble Rammurti T Bollard Catherine M Gee Adrian P Mei Zhuyong Liu Hao Grilley Bambi Rooney Cliona M Heslop Helen E Brenner Malcolm K Dotti Gianpie | 2011 | Journal of Clinical Investigation2011，，5： | 1 |
| 13 | The cost of soil erosion in vineyard fields in the Penede' s - Anoia Region ( NE Spain) 显示文摘 | Martinez - Casasnovas J A Ramos M C | 2006 | Catena2006，68，3： | 1 |
| 14 | Linkage of a geographical information system with the GLEAMS model to assess nitrate leaching in agricultural areas显示文摘 | De Paza J M Ramos C | 2002 | Environ Pollut2002，118，： | 1 |
| 15 | Sequential Superheated Liquid Extraction of Pesticides, Pharmaceutical and Personal Care Products with Different Polarity from Marine Sediments Followed by Gas Chromatography Mass Spectrometry Detection显示文摘 | MORALES-MUNOZS LUQUE-GARCaA J L RAMOS M J | 2005 | Analytica Chimica Acta2005，552，： | 1 |
| 16 | Sequential extraction of copper, lead, cadmium and zinc in sediments from Ebro River (Spain) :Relationship with levels detected in earthworms显示文摘 | RAMOS L GONZALEZ M J HEMANDEZ L M | 1999 | Bull Environ Contain Toxic1999，62，： | 1 |
| 17 | Comparative ecology of seed mass in Paychotria (Rubiaceae) Within and between species effects of seed mass on early performance显示文摘 | PAZ H MAZER S J MARTINEZ RAMOS M | 2005 | Functional Ecology2005，19，4： | 1 |
| 18 | Comparative structural analysis of et-glucosidase inhibitors on difference species: a computational study 显示文摘 | Narayana Moorthy N S Ramos M J Fernandes P A | 2012 | Arch Pharm (Weinheim)2012，345，4： | 1 |
| 19 | Comparative study of different methods for evaluating proteolysis in blue cheese显示文摘 | RAMOS M MARTIN-ALVAREZ P J | 1993 | Z Lebensm Unters Forsch1993，196，： | 1 |
| 20 | Adsorption of fluoride from aqueous solution on aluminum-impregnated carbon显示文摘 | Ramos L R Ovalle-Turrubiartes J Sanchez-Castillo M A | 1999 | Carbon1999，37，： | 1 |
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