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| 1 | Shear wave velocity structure of the crust and upper mantle underneath the Tianshan orogenic belt显示文摘From April, 2003 to September, 2004, a passive broadband seismic array consisting of 60 stations was deployed over the Tianshan orogenic belt by State Key Laboratory of Earthquake Dynamics, Institute of Geology, China Earthquake Administration. Among them, 51 stations make up an about 500-km-long profile across the Tianshan Mountains from Kuytun to Kuqa. The receiver function profile and S-wave velocity structure of the crust and upper mantle down to 100 km deep are obtained by using the re-ceiver function method (Liu et al. 1996, 2000). The main results can be summarized as follows: (1) A clear mountain root does not exist beneath the Tianshan Mountains, and the crust-mantle boundaries underneath the stations mostly have transitional structures. This implies that the material differentia-tion between the crust and mantle is not yet accomplished and the orogenic process is still going on. (2) The crust beneath the Tianshan Mountains has laterally blocked structures in direction perpendicular to the mountain strike, and the crust-mantle boundary has a clear dislocation structure. Both of them correspond to each other. (3) The offsets of the Moho discontinuity are highly correlated to the tectonic borders on the surface and that corresponding to the frontal southern Tianshan fault reaches to 14 km. This manifests that large vertical divergent movement took place between different blocks. This sup-ports the discontinuous model of the Tianshan orogeny, and the Tarim block subduction is restricted only to the southern side of the South Tianshan. (4) Inside the upper and middle crust of the Tianshan Mountains exist several low-velocity bodies correlated with high seismicity located on the moun-tain-basin jointures on both sides of the mountain and between different blocks, and the low-velocity bodies on the mountain-basin jointures are inclined obviously to the mountain. This implies that the low-velocity bodies may be correlated closely to the thrust and subduction of the basins on both sides of the mountain, the splicing of adjacent blocks and the fast uplift of the Tianshan Mountains. | LI Yu LIU QiYuan CHEN JiuHui LI ShunCheng GUO Biao LAI YuanGen | 2007 | Science China Earth Sciences2007，50，3： | 16 |
| 2 | Vast laminated diatom mat deposits from the west low-latitude Pacific Ocean in the last glacial period显示文摘Diatoms are one of the predominant contributors to global carbon fixation by accounting for over 40% of total oceanic primary production and dominate export production. They play a significant role in marine biogeochemistry cycle. The diatom mat deposits are results of vast diatoms bloom. By analysis of diatom mats in 136°00′―140°00′E,15°00′―21°00′N, Eastern Philippines Sea, we identified the species of the diatoms as giant Ethmodiscus rex (Wallich) Hendey. AMS 14C dating shows that the sediments rich in diatom mats occurred during 16000―28600 a B.P., which means the bloom mainly occurred during the last glacial period, while there are no diatom mat deposits in other layers. Preliminary analysis indicates that Antarctic Intermediate Water (AAIW) expanded northward and brought silicate-rich water into the area, namely, silicon leakage processes caused the bloom of diatoms. In addition, the increase of iron input is one of the main reasons for the diatom bloom. | ZHAI Bin LI TieGang CHANG FengMing CAO QiYuan | 2009 | Chinese Science Bulletin2009，54，23： | 9 |
| 3 | 3D printed silk-gelatin hydrogel scaffold with different porous structure and cell seeding strategy for cartilage regeneration显示文摘Hydrogel scaffolds are attractive for tissue defect repair and reorganization because of their human tissue-like characteristics.However,most hydrogels offer limited cell growth and tissue formation ability due to their submicron-or nano-sized gel networks,which restrict the supply of oxygen,nutrients and inhibit the proliferation and differentiation of encapsulated cells.In recent years,3D printed hydrogels have shown great potential to overcome this problem by introducing macro-pores within scaffolds.In this study,we fabricated a macroporous hydrogel scaffold through horseradish peroxidase(HRP)-mediated crosslinking of silk fibroin(SF)and tyramine-substituted gelatin(GT)by extrusion-based low-temperature 3D printing.Through physicochemical characterization,we found that this hydrogel has excellent structural stability,suitable mechanical properties,and an adjustable degradation rate,thus satisfying the requirements for cartilage reconstruction.Cell suspension and aggregate seeding methods were developed to assess the inoculation efficiency of the hydrogel.Moreover,the chondrogenic differentiation of stem cells was explored.Stem cells in the hydrogel differentiated into hyaline cartilage when the cell aggregate seeding method was used and into fibrocartilage when the cell suspension was used.Finally,the effect of the hydrogel and stem cells were investigated in a rabbit cartilage defect model.After implantation for 12 and 16 weeks,histological evaluation of the sections was performed.We found that the enzymatic cross-linked and methanol treatment SF5GT15 hydrogel combined with cell aggregates promoted articular cartilage regeneration.In summary,this 3D printed macroporous SF-GT hydrogel combined with stem cell aggregates possesses excellent potential for application in cartilage tissue repair and regeneration. | Qingtao Li Sheng Xu Qi Feng Qiyuan Dai Longtao Yao Yichen Zhang Huichang Gao Hua Dong Dafu Chen Xiaodong Cao | 2021 | Bioactive Materials2021，6，10： | 6 |
| 4 | Crustal structure beneath the Qilian Orogen Zone from multiscale seismic tomography显示文摘The Qilian Orogen Zone(QOZ), located in the north margin of the Tibetan Plateau, is the key area for understanding the deformation and dynamics process of Tibet. Numerous geological and geophysical studies have been carried out on the mechanics of the Tibetan Plateau deformation and uplift; however, the detailed structure and deformation style of the Qilian Orogen Zone have remained uncertain due to poor geophysical data coverage and limited resolution power of inversion algorithms. In this study, we analyze the P-wave velocity structure beneath the Qilian Orogen Zone, obtained by applying multi-scale seismic tomography technique to P-wave arrival time data recorded by regional seismic networks. The seismic tomography algorithm used in this study employs sparsity constraints on the wavelet representation of the velocity model via L1-norm regularization. This algorithm can deal efficiently with uneven-sampled volumes, and can obtain multi-scale images of the velocity model. Our results can be summarized as follows:(1) The crustal velocity structure is strongly inhomogeneous and consistent with the surface geological setting. Significant low-velocity anomalies exist in the crust of northeastern Tibet, and slight high-velocity anomalies exist beneath the Qaidam Basin and Alxa terrane.(2)The Qilian Orogen Zone can be divided into two main parts by the Laji Shan Faults: the northwestern part with a low-velocity feature, and the southeastern part with a high-velocity feature at the upper and middle crust.(3) Our tomographic images suggest that northwestern and southeastern Qilian Orogen Zones have undergone different tectonic processes. In the northwest Qilian Orogen Zone, the deformation and growth of the Northern Tibetan Plateau has extended to the Heli Shan and Beida Shan region by northward overthrusting at the upper crust and thickening in the lower crust. We speculate that in the southeast Qilian Orogen Zone the deformation and growth of the Northern Tibet Plateau were of strike-slip style at the upper crust; in the lower crust, the evidence suggests ductile shear extrusion style and active frontage extension to the Alxa terrane.(4) The multi-scale seismic tomography technique provides multiscale analysis and sparse constraints, which has allowed to us obtain stable, high-resolution results. | Biao Guo JiuHui Chen QiYuan Liu ShunCheng Li | 2019 | Earth and Planetary Physics2019，3，3： | 5 |
| 5 | First experimental constraints on WIMP couplings in the effective field theory framework from CDEX显示文摘We present weakly interacting massive particles(WIMPs) search results performed using two approaches of effective field theory from the China Dark Matter Experiment(CDEX), based on the data from both CDEX-1B and CDEX-10 stages. In the nonrelativistic effective field theory approach, both time-integrated and annual modulation analyses were used to set new limits for the coupling of WIMP-nucleon effective operators at 90% confidence level(C.L.) and improve over the current bounds in the low mχregion. In the chiral effective field theory approach, data from CDEX-10 were used to set an upper limit on WIMP-pion coupling at 90% C.L. We for the first time extended the limit to the m_(χ)<6 GeV/c^(2) region. | Yi Wang Zhi Zeng Qian Yue LiTao Yang KeJun Kang YuanJing Li Mehment Agartioglu HaiPeng An JianPing Chang JingHan Chen YunHua Chen JianPing Cheng Cheng Yi Chiang WenHan Dai Zhi Deng ChangHao Fang XinPing Geng Hui Gong QiuJu Guo XuYuan Guo HongJian He Li He ShengMing He JinWei Hu TuChen Huang HanXiong Huang HaiTao Jia LiPing Jia Xi Jiang HauBin Li JianMin Li Jin Li MingXuan Li RenMingJie Li Xia Li YuLan Li Bin Liao FongKay Lin ShinTed Lin ShuKui Liu YanDong Liu Yu Liu YuanYuan Liu ZhongZhi Liu Hao Ma YuCai Mao QiYuan Nie JinHua Ning Hui Pan NingChun Qi Jie Ren XiChao Ruan ChangSong Shang Vivek Sharma Ze She Lakhwinder Singh Monoj Kumar Singh TianXi Sun ChangJian Tang WeiYou Tang Yang Tian GuangFu Wang Li Wang Qing Wang Yu Chen Wang YunXiang Wang Zhen Wang Henry Tsz-King Wong ShiYong Wu YuCheng Wu HaoYang Xing Yin Xu Tao Xue YuLu Yan Nan Yi ChunXu Yu HaiJun Yu JianFeng Yue Ming Zeng BingTao Zhang Lei Zhang FengShou Zhang ZhenYu Zhang KangKang Zhao MingGang Zhao JiFang Zhou ZuYing Zhou JingJun Zhu | 2021 | Science China(Physics,Mechanics & Astronomy)2021，64，8： | 3 |
| 6 | The structural model of P_(680)显示文摘INVESTIGATION on photosystem Ⅱ (PS Ⅱ ) of high plants is one of the most important aspects in photosynthesis research. P680 is the primary electron donor in reaction center of PS Ⅱ , which is a crucial component for sun-light conversion and water split in PS Ⅱ. So study on its structure and function is very important. So far, a few structural models of P(680) have been proposed. Typical models are monomolecular model and bimolecular model. There are two types of bimolecular model: bimolecular parallel model and bimolecular angular model. (Note: There is a kind of multiple model. Because it can be obtained from the organization of two bimolecular models, this model is considered as the same sort of bi- | ZHANG Chunxi , ZHANG Xiaodong , LI Liangbi , ZHANG Qiyuan , ZHANG Xingkang and KUANG TingyunPhotosynthesis Research Center and Laboratory of Photosynthesis Basic Research , Institute of Botany , Chinese Academy of Sciences , Beijing 100093, China State Key Laboratory for Structural Chemistry of Unstable and Stable Species , Institute of Chemistry, Chinese Academy of Sciences , Beijing 100080, China | 1999 | Chinese Science Bulletin1999，44，9： | 3 |
| 7 | Impact of COVID-19 lockdown on the optical properties and radiative effects of urban brown carbon aerosol显示文摘Intensive measurements were conducted in Xi’an,China before and during a COVID-19 lockdown period to investigate how changes in anthropogenic emissions affected the optical properties and radiative effects of brown carbon(BrC)aerosol.The contribution of BrC to total aerosol light absorption during the lockdown(13%-49%)was higher compared with the normal period(4%-29%).Mass absorption cross-sections(MACs)of specific organic aerosol(OA)factors were calculated from a ridge regression model.Of the primary OA(POA),coal combustion OA(CCOA)had the largest MACs at all tested wave-lengths during both periods due to high molecular-weight BrC chromophores;that was followed by biomass burning OA(BBOA)and hydrocarbon-like OA(HOA).For secondary OA(SOA),the MACs of the lessoxidized oxygenated OA(OOA)species(LO-OOA)atλ=370-590 nm were higher than those of more-oxidized OOA(MO-OOA)during both periods,presumably due to chromophore bleaching.The largest contributor to BrC absorption at the short wavelengths was CCOA during both periods,but BrC absorption by LO-OOA and MO-OOA became dominant at longer wavelengths during the lockdown.The estimated radiation forcing efficiency of BrC over 370-600 nm increased from 37.5 W·gduring the normal period to 50.2 W·gduring the lockdown,and that enhancement was mainly caused by higher MACs for both LO-OOA and MO-OOA.This study provides insights into the optical properties and radiative effects of source-specific BrC aerosol when pollution emissions are reduced. | Yong Zhang Qiyuan Wang Jie Tian Yu Li Huikun Liu Weikang Ran Yongming Han AndréS.H.Prévot Junji Cao | 2022 | Geoscience Frontiers2022，13，6： | 3 |
| 8 | Observable-specific phase biases of Wuhan multi-GNSS experiment analysis center’s rapid satellite products显示文摘Precise Point Positioning(PPP)with Ambiguity Resolution(AR)is an important high-precision positioning technique that is gaining popularity in geodetic and geophysical applications.The implementation of PPP-AR requires precise products such as orbits,clocks,code,and phase biases.As one of the analysis centers of the International Global Navigation Satellite System(GNSS)Service(IGS),the Wuhan University Multi-GNSS experiment(WUM)Analysis Center(AC)has provided multi-GNSS Observable-Specific Bias(OSB)products with the associated orbit and clock products.In this article,we first introduce the models and generation strategies of WUM rapid phase clock/bias products and orbit-related products(with a latency of less than 16 h).Then,we assess the performance of these products by comparing them with those of other ACs and by testing the PPP-AR positioning precision,using data from Day of the Year(DOY)047 to DOY 078 in 2022.It is found that the peak-to-peak value of phase OSBs is within 2 ns,and their fluctuations are caused by the clock day boundary discontinuities.The associated Global Positioning System(GPS)orbits have the best consistency with European Space Agency(ESA)products,and those of other systems rank in the medium place.GLObal NAvigation Satellite System(GLONASS)clocks show slightly inconsistency with other ACs’due to the antenna thrust power adopted,while the phase clocks of other GNSSs show no distortion compared with legacy clocks.With well-estimated phase products for Precise Orbit Determination(POD),the intrinsic precision is improved by 14%,17%,and 24%for GPS,Galileo navigation satellite system(Galileo),and BeiDou-3 Navigation Satellite System(BDS-3),respectively.The root mean square of PPP-AR using our products in static mode with respect to IGS weekly solutions can reach 0.16 cm,0.16 cm,and 0.44 cm in the east,north,and up directions,respectively.The multi-GNSS wide-lane ambiguity fixing rates are all above 90%,while the narrow-lane fixing rates above 80%.In conclusion,the phase OSB products at WUM have good precision and performance,which will benefit multi-GNSS PPP-AR and POD. | Jianghui Geng Qiyuan Zhang Guangcai Li Jingnan Liu Donglie Liu | 2022 | Satellite Navigation2022，3，3： | 3 |
| 9 | A field-effect approach to directly profiling the localized states in monolayer MoS2显示文摘A fundamental understanding of the charge transport mechanism in two-dimensional semiconductors(e.g., MoS2) is crucial for fully exploring their potential in electronic and optoelectronic devices. By using monolayer graphene as the barrier-free contact to MoS2, we show that the field-modulated conductivity can be used to probe the electronic structure of the localized states. A series of regularly distributed plateaus were observed in the gate-dependent transfer curves. Calculations based on the variable-range hopping theory indicate that such plateaus can be attributed to the discrete localized states near mobility edge. This method provides an effective approach to directly profiling the localized states in conduction channel with an ultrahigh resolution up to 1 meV. | Hao Wu Yuan Liu Zeyu Deng Hung-Chieh Cheng Dehui Li Jian Guo Qiyuan He Sen Yang Mengning Ding Yun-Chiao Huang Chen Wang Yu Huang Xiangfeng Duan | 2019 | Science Bulletin2019，64，15： | 2 |
| 10 | Toll-like receptor 9 defciency induces osteoclastic bone loss via gut microbiota-associated systemic chronic inflammation显示文摘Toll-like receptors(TLRs)play pivotal roles in inflammation and provide important links between the immune and skeletal systems.Although the activation of TLRs may affect osteoclast differentiation and bone metabolism,whether and how TLRs are required for normal bone remodeling remains to be fully explored.In the current study,we show for the first time that TLR9^(-/-)mice exhibit a low bone mass and low-grade systemic chronic inflammation,which is characterized by the expansion of CD4^(+)T cells and increased levels of inflammatory cytokines,including TNFα,RANKL,and IL1β.The increased levels of these cytokines significantly promote osteoclastogenesis and induce bone loss.Importantly,TLR9 deletion alters the gut microbiota,and this dysbiosis is the basis of the systemic inflammation and bone loss observed in TLR9^(-/-)mice.Furthermore,through single-cell RNA sequencing,we identified myeloid-biased hematopoiesis in the bone marrow of TLR9^(-/-)mice and determined that the increase in myelopoiesis,likely caused by the adaptation of hematopoietic stem cells to systemic inflammation,also contributes to inflammation-induced osteoclastogenesis and subsequent bone loss in TLR9^(-/-)mice.Thus,our study provides novel evidence that TLR9 signaling connects the gut microbiota,immune system,and bone and is critical in maintaining the homeostasis of inflammation,hematopoiesis,and bone metabolism under normal conditions. | Peng Ding Qiyuan Tan Zhanying Wei Qiyu Chen Chun Wang Luyue Qi Li Wen Changqing Zhang Chen Yao | 2022 | Bone Research2022，10，3： | 2 |
| 11 | Impacts of Aerosol−Radiation Interactions on the Wintertime Particulate Pollution under Different Synoptic Patterns in the Guanzhong Basin,China显示文摘The effects of aerosol-radiation interactions(ARI)are not only important for regional and global climate,but they can also drive particulate matter(PM)pollution.In this study,the ARI contribution to the near-surface fine PM(PM_(2.5))concentrations in the Guanzhong Basin(GZB)is evaluated under four unfavorable synoptic patterns,including“northlow”,“transition”,“southeast-trough”,and“inland-high”,based on WRF-Chem model simulations of a persistent heavy PM pollution episode in January 2019.Simulations show that ARI consistently decreases both solar radiation reaching down to the surface(SWDOWN)and surface temperature(TSFC),which then reduces wind speed,induces sinking motion,and influences cloud formation in the GZB.However,large differences under the four synoptic patterns still exist.The average reductions of SWDOWN and daytime TSFC in the GZB range from 15.2%and 1.04°C in the case of the“transition”pattern to 26.7%and 1.69°C in the case of the“north-low”pattern,respectively.Furthermore,ARI suppresses the development of the planetary boundary layer(PBL),with the decrease of PBL height(PBLH)varying from 18.7%in the case of the“transition”pattern to 32.0%in the case of the“north-low”pattern.The increase of daytime near-surface PM_(2.5)in the GZB due to ARI is 12.0%,8.1%,9.5%,and 9.7%under the four synoptic patterns,respectively.Ensemble analyses also reveal that when near-surface PM_(2.5)concentrations are low,ARI tends to lower PM_(2.5)concentrations with decreased PBLH,which is caused by enhanced divergence or a transition from divergence to convergence in an area.ARI contributes 15%-25%toward the near-surface PM_(2.5)concentrations during the severe PM pollution period under the four synoptic patterns. | Naifang BEI Xia LI Qiyuan WANG Suixin LIU Jiarui WU Jiayi LIANG Lang LIU Ruonan WANG Guohui LI | 2021 | Advances in Atmospheric Sciences2021，38，7： | 2 |
| 12 | RAMAN SPECTRAL STUDY ON ISOPOLYTUNGSTATES IN AQUEOUS SOLUTION显示文摘INTRODUCTIONAlargenumberofstudieshavebendoneinthefieldoftheaqueouschemistryofisopolytungstateusingnumerousexperimentalmetho... | Liu, Shijun Chen, Qiyuan Zhang, Pingmin Li, Songqin | 1998 | 中国有色金属学会会刊:英文版1998，8，4： | 2 |
| 13 | An Integrated Method Used to Value Recreation Land–a Case Study of Sweden显示文摘 | Minghao Liu Xiaobo Luo Qiyuan Li | 2012 | Energy Procedia2012，，： | 1 |
| 14 | Study on kinetics of the thermal decompositions of ammonium molybdates 显示文摘 | Yin Zhoulan Li Xinhai Chen Qiyuan | 2000 | Thermochimica Acta2000，352，1： | 1 |
| 15 | Visible light photoelectrochemical responsiveness of self-organized nanoporous WO 3 films显示文摘 | Wenzhang Li Jie Li Xuan Wang Sha Luo Juan Xiao Qiyuan Chen | 2010 | Electrochimica Acta2010，，1： | 1 |
| 16 | Fabrication of Flexible MoS<sub>2</sub> Thin‐Film Transistor Arrays for Practical Gas‐Sensing Applications显示文摘 | Qiyuan He Zhiyuan Zeng Zongyou Yin Hai Li Shixin Wu Xiao Huang Hua Zhang | 2012 | Small2012，，19： | 1 |
| 17 | PREPARATION AND PROPERTIES OF THE MICRO-POWDER PHASE AND A NEW PHASE OF AMMONIUM TETRAMOLYBDATES显示文摘PREPARATIONANDPROPERTIESOFTHEMICROPOWDERPHASEANDANEWPHASEOFAMMONIUMTETRAMOLYBDATES①YinZhoulan,ChenQiyuan,ZhangHengzhong,Zhou... | Yin, Zhoulan Chen, Qiyuan Zhang, Hengzhong Zhou, Guizhi Li, Yuangao Zhang, Pingmin | 1997 | 中国有色金属学会会刊:英文版1997，7，1： | 1 |
| 18 | Amplification of LAPTM4B and YWHAZ contributes to chemotherapy re-sistance and recurrence of breast cancer显示文摘 | Yang Li Lihua Zou Qiyuan Li | | 0，，02： | 1 |
| 19 | The Beijing Astronomical Observatory supernova survey (II)显示文摘 | Weidong Li Yulei Qiu Qiyuan Qiao Jingyao Hu Qibin Li | 1999 | Science in China Series A: Mathematics1999，，10： | 1 |
| 20 | Supernova survey system in beijing astronomical Observatory (I)显示文摘 | Yulei Qiu Weidong Li Zhaowang Zhao Qiyuan Qiao Yong Rao Jingyao Hu Qibin Li | 1999 | Science in China Series A: Mathematics1999，，2： | 1 |
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