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| 1 | 选区激光熔化和传统粉末冶金法制备Cu−Al−Ni−Mn−Zr形状记忆合金的对比显示文摘研究和分析选区激光熔化(SLM)与传统粉末冶金(PM)法制备Cu−11.3Al−3.2Ni−3.0Mn−0.5Zr形状记忆合金的显微组织特征和热稳定性差异。PM样品是将106~180μm预合金粉末在氩气气氛、1060℃下烧结制备的,无辅助加工,SLM样品是在Cu−10Sn基板上熔化32~106μm的预合金粉末制备的。通过维氏硬度试验评价材料的力学性能,采用差示扫描量热法测定马氏体相变温度,采用X射线衍射谱鉴定相成分,利用光学显微镜和扫描电子显微镜分析显微组织特征。结果表明,两种方法制备的合金中均发现β′1马氏体相,而在PM样品中存在粗大的马氏体变体。传统的粉末冶金样品在室温下会形成晶间共析成分和稳定的奥氏体。PM样品具有与SLM样品相似的平均硬度值,而与孔隙率相关的标准偏差较高。SLM样品具有可逆的马氏体相变(T0=171℃),而PM样品没有形状记忆效应。 | Dennis GERA Jonadabe SANTOS Cláudio SKIMINAMI Piter GARGARELLA | 2020 | Transactions of Nonferrous Metals Society of China2020，30，12： | 4 |
| 2 | The wide spectrum of multidrug resistance 3 deficiency: From neonatal cholestasis to cirrhosis of adulthood显示文摘 | Emmanuel Jacquemin J. Marleen L. De Vree Danièle Cresteil Etienne M. Sokal Ekkehard Sturm Micheline Dumont George L. Scheffer Marianne Paul Martin Burdelski Piter J. Bosma Olivier Bernard Michelle Hadchouel Ronald P.J. Oude Elferink | 2001 | Gastroenterology2001，，6： | 2 |
| 3 | Overview of MTA in the treatment of non-small cell lung cancer显示文摘 | Piter E Postmus and Green MR | 1999 | Semin Oncol1999，26，： | 1 |
| 4 | Crigler‐Najjar syndrome in The Netherlands: Identification of four novel UGT1A1 alleles, genotype–phenotype correlation, and functional analysis of 10 missense mutants显示文摘 | NinaSneitz Conny T.Bakker Robert J.de Knegt Dicky J.J.Halley MosheFinel Piter J.Bosma | 2009 | Hum Mutat2009，，1： | 1 |
| 5 | Wnt sigdaling:A win for bone显示文摘 | Piters E Boudin E Van Hul W | 2008 | Arch Biochem Biophys2008，473，2： | 1 |
| 6 | Adaptation of the rapid automated tetrazolium dye based (MTT) assay for Chemosensitivity testing in child leukaemia显示文摘 | Piter R Huismans DR Leyva A | 1988 | Cancer lett1988，41，3： | 1 |
| 7 | The Binding Between Sclerostin and LRP5 is Altered by DKK1 and by High-Bone Mass LRP5 Mutations显示文摘 | Wendy Balemans Elke Piters Erna Cleiren Minrong Ai Liesbeth Wesenbeeck Matthew L. Warman Wim Hul | 2008 | Calcified Tissue International2008，，6： | 1 |
| 8 | Inorganic geochemical indicators of glacial interglacial changes in productivity and anoxia on the California continental margin显示文摘 | Dean W Gardner J Piter D | 1997 | Geochimica et Cosmochimica Acta1997，61，： | 1 |
| 9 | Wnt signaling: a win for bone 显示文摘 | Piters E Boudin E Van HuI W | 2008 | Arch Biochem Biophys2008，473，2： | 1 |
| 10 | A maximum en- tropy approach to natural language processing 显示文摘 | BERGER A PIETRA S D PITER V D | 1996 | Computer Linguistics1996，22，1： | 1 |
| 11 | The role of extracellular modulators of canonical Wnt signaling in bone metabolism and diseases显示文摘 | Boudin E Fijalkowski I Piters E | 2013 | Semin Arthritis Rheum2013，43，2： | 1 |
| 12 | Ephrin A2 receptor targeting does not increase adenoviral pancreatic cancer transduction in vivo显示文摘AIM:To generate an adenoviral vector specifically targeting the EphA2 receptor(EphA2R) highly expressed on pancreatic cancer cells in vivo.METHODS:YSA,a small peptide ligand that binds the EphA2R with high affinity,was inserted into the HI loop of the adenovirus serotype 5 fiber knob.To further increase the specificity of this vector,binding sites for native adenoviral receptors,the coxsackie and adenovirus receptor(CAR) and integrin,were ablated from the viral capsid.The ablated retargeted adenoviral vector was produced on 293T cells.Specifi c targeting of this novel adenoviral vector to pancreatic cancer was investigated on established human pancreatic cancer cell lines.Upon demonstrating specifi c in vitro targeting,in vivo targeting to subcutaneous growing human pancreatic cancer was tested by intravenous and intraperitoneal administration of the ablated adenoviral vector.RESULTS:Ablation of native cellular binding sites reduced adenoviral transduction at least 100-fold.Insertion of the YSA peptide in the HI loop restored adenoviral transduction of EphA2R-expressing cells but not of cells lacking this receptor.YSA-mediated transduction was inhibited by addition of synthetic YSA peptide.The transduction specificity of the ablated retargeted vector towards human pancreatic cancer cells was enhanced almost 10-fold in vitro.In a subsequent in vivo study in a nude(nu/nu) mouse model however,no increased adenoviral targeting to subcutaneously growing human pancreas cancer nodules was seen upon injection into the tail vein,nor upon injection into the peritoneum.CONCLUSION:Targeting the EphA2 receptor increases specificity of adenoviral transduction of human pancreatic cancer cells in vitro but fails to enhance pancreatic cancer transduction in vivo. | Michael A van Geer Conny T Bakker Naoya Koizumi Hiroyuki Mizuguchi John G Wesseling Ronald PJ Oude Elferink Piter J Bosma | 2009 | World Journal of Gastroenterology2009，15，22： | 1 |
| 13 | The prognostic significance of membrance transport-associated multiding resistance(MDR) proteins in leukemia显示文摘 | Van den Heuvel-Eibrink MM Scnneveld P Piters R | 2000 | Clin Pharmacol Ther2000，38，3： | 1 |
| 14 | Inorganic geochemical indicators of glacial-interglacial changes in productivity and anoxia on the California continental margin 显示文摘 | Dean W E Gardner J V and Piter D Z | 1997 | Geochimica et Cosmochimica Acta1997，61，21： | 1 |
| 15 | The binding between sclerostin and LRP5 is altered by Dkk-1 and by high-bone mass LRP5 mutation 显示文摘 | BALEMANS W PITERS E CLEIREN E | 2008 | Calcif Tissue Int2008，82，6： | 1 |
| 16 | Tough polylactide graft copolymer 显示文摘 | THERYO G JING F PITER L M | 2010 | Macromolecules2010，43，18： | 1 |
| 17 | Overview of SCIAMACHY Validation: 2002-2004显示文摘 | Piters A J M Bramstedt K Lambert J C | 2006 | Atmospheric Chemistry and Physics2006，6，： | 1 |
| 18 | Limitation of peak fitting and peak shape methods for determination of activation energy of thermoluminescence glow peaks 显示文摘 | Sunta Ayta C M Feria W E Piters T M | 1999 | Radiation Measurements1999，30，： | 1 |
| 19 | Global and hemispheric CO2 sinks deduced from changes in atmo spheric Oz concentration 显示文摘 | KEELING R F PITER S C HEIMANN M | 1996 | Nature1996，381，6579： | 1 |
| 20 | Thermodynamics of electrolytes II Activity and osmiotic coefficients for strong electrolytes with one or both ions univalent显示文摘 | PITER K S MAYORGA G | 1973 | The Journal of Physical Chemistry1973，77，19： | 1 |
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