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| 1 | Seismic response of continuous span bridges through fiber-based finite element analysis显示文摘非线性的时间历史分析组成最精确的方法模仿受到地震刺激的强壮的层次的结构的反应,这广泛地被认出。这个分析方法基于位于原则下面的声音并且有能力撕生产结构的内在的无弹性的动态行为。尽管如此,有从结构的大规模测试的试验性的结果的比较仍然被需要,以便在这数字方法论保证信心的足够的层次。在当前的努力采用的纤维建模途径内在地说明几何非线性和材料无弹力,没有对塑料绞链机制的刻度的需要,在集中的粘性模型典型。分析精确性和建模简洁的产生联合,这样允许克服也许,复杂性的不充分有理由的感觉联系了到非线性的动态分析。基于纤维的建模途径在为加框的的结构的地震反应分析从因特网下载的一个有限元素节目的框架被采用。节目的 Thereliability 和精确性被数字地在四跨度上复制 pseudo-dynamictests 表明连续甲板水泥桥牌。建模假设被讨论,和他们非线性的时间历史分析的数字结果上的含意,它被发现在对试验性的结果的好同意。 | Chiara Casarotti Rui Pinho | 2006 | Earthquake Engineering and Engineering Vibration2006，5，1： | 9 |
| 2 | Review of small-bowel cleansing scales in capsule endoscopy: A panoply of choices显示文摘Evaluation of the quality of small-bowel cleansing is required to assess the reliability of findings in capsule endoscopy(CE). Moreover, consensus regarding the need of intestinal preparation for CE remains to be achieved. The presence of multiple grading scales for smallbowel preparation in CE, which are time-consuming and complicated, adds difficulty to the comparison of different small-bowel cleansing regimens and their application in clinical practice. Nowadays, a validated scale universally accepted for grading small-bowel cleansing is lacking. In fact, there are numerous grading systems with very different technical characteristics, namely, the parameters and the portion of the CE video that are analyzed, the objectivity of the analysis, the lesser or greater dependency on the operator, and the validation of the score. The authors performed a review which aims to systematize and summarize currently available smallbowel grading scales in CE. | Ana Ponte Rolando Pinho Adélia Rodrigues Joao Carvalho | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，17： | 6 |
| 3 | Landslide susceptibility mapping using the infinite slope,SHALSTAB,SINMAP,and TRIGRS models in Serra do Mar,Brazil显示文摘Slope failure triggered by heavy rainfall is very common in tropical and subtropical regions and a cause of major social and economic damage.Landslide susceptibility maps can be generated using geographical information systems(GIS)and limit equilibrium slope stability models coupled or not to hydrological equations.This study investigated the efficacy of four models used for slope stability analysis in predicting landslide-susceptible areas in a GIS environment.The selected models are the infinite slope,the shallow slope stability model(SHALSTAB),the stability index mapping(SINMAP),and the transient rainfall infiltration and grid-based regional slope-stability(TRIGRS).For comparisons,the authors(a)included the infinite slope equation in all models,(b)clearly defined input parameters and failure triggering mechanisms for each simulation(soil depth,water table height,rainfall intensity),(c)determined appropriate values for each model to obtain stability levels that represented similar hydrogeotechnical conditions,and(d)considered upper-third areas of landslide scars to estimate the reliability of susceptibility maps using validation indices.An intense rainfall event occurred in Serra do Mar,Brazil in January 2014 triggered hundreds of landslides and was used for back analysis and evaluation of the slope stability analysis models.When rainfall intensity is not considered,the four models produced very similar results.The most reliable landslide susceptibility map was generated using TRIGRS and considering the granite residual granite soils geological-geotechnical unit,subjected to a rainfall intensity of 210 mm for 2 h under unsaturated conditions. | Thiago Machado do PINHO Oswaldo AUGUSTO FILHO | 2022 | Journal of Mountain Science2022，19，4： | 5 |
| 4 | Chronic pancreatitis: A path to pancreatic cancer显示文摘 | Andreia V. Pinho Lorraine Chantrill Ilse Rooman | 2014 | Cancer Letters2014，，2： | 3 |
| 5 | Differences in viral kinetics between genotypes 1 and 3 of hepatitis C virus and between cirrhotic and non-cirrhotic patients during antiviral therapy显示文摘AIM: To evaluate the impact of hepatitis C virus (HCV) infection with genotype 1 or 3 and the presence or absence of liver cirrhosis (LC) in the early viral kinetics response to treatment. METHODS: Naive patients (n = 46) treated with interferon-α (IFN-α) and ribavirin and followed up with frequent early HCV-RNA determinations were analysed. Patients were infected with genotype 1 (n = 28, 7 with LC) or 3 (n = 18, 5 with LC). RESULTS: The fi rst phase decline was larger in geno- type 3 patients than in genotype 1 patients (1.72 vs 0.95 log IU/mL, P < 0.001). The second phase slope decline was also larger in genotype 3 patients than in genotype 1 patients (0.87 vs 0.15 log/wk, P < 0.001). Differences were found in both cirrhotic and non-cirrhotic patients. Genotype 1 cirrhotic patients had a slower 2nd phase slope than non-cirrhotic patients (0.06 vs 0.18 log/wk, P < 0.02). None of genotype 1 cirrhotic patients had a 1st phase decline larger than 1 log (non-cirrhotic patients: 55%, P < 0.02). A similar trend toward a slower 2nd phase slope was observed in genotype 3 cirrhotic pa- tients but the 1st phase slope decline was not different. Sustained viral response was higher in genotype 3 pa- tients than in genotype 1 patients (72% vs 14%, P < 0.001) and in genotype 1 non-cirrhotic patients than in genotype 1 cirrhotic patients (19% vs 0%). A secondphase decline slower than 0.3 log/wk was predictive of non-response in all groups. CONCLUSION: Genotype 3 has faster early viral decline than genotype 1. Cirrhosis correlates with a slower 2nd phase decline and possibly with a lower 1st phase slope decline in genotype 1 patients. | José Eymard Medeiros-Filho Isabel Maria Vicente Guedes de Carvalho Mello Joo Renato Rebello Pinho Avidan U Neumann Fernanda de Mello Malta Luiz Caetano da Silva Flair José Carrilho | 2006 | World Journal of Gastroenterology2006，12，45： | 3 |
| 6 | Essential role of small bowel capsule endoscopy in reclassification of colonic inflammatory bowel disease type unclassified显示文摘AIM To evaluate the role of small bowel capsule endoscopy(SBCE) on the reclassification of colonic inflammatory bowel disease type unclassified(IBDU).METHODS We performed a multicenter, retrospective study including patients with IBDU undergoing SBCE, between 2002 and 2014. SBCE studies were reviewed and the inflammatory activity was evaluated by determining the Lewis score(LS). Inflammatory activity was considered significant and consistent with Crohn's disease(CD) when the LS ≥ 135. The definitive diagnosis during follow-up(minimum 12 mo following SBCE) was based on the combination of clinical, analytical, imaging, endoscopic and histological elements.RESULTS Thirty-six patients were included, 21 females(58%) with mean age at diagnosis of 33 ± 13(15-64) years. The mean follow-up time after the SBCE was 52 ± 41(12-156) mo. The SBCE revealed findings consistent with significant inflammatory activity in the small bowel(LS ≥ 135) in 9 patients(25%); in all of them the diagnosis of CD was confirmed during follow-up. In 27 patients(75%), the SBCE revealed no significant inflammatory activity(LS < 135); among these patients, the diagnosis of Ulcerative Colitis(UC) was established in 16 cases(59.3%), CD in 1 case(3.7%) and 10 patients(37%) maintained a diagnosis of IBDU during follow-up. A LS ≥ 135 at SBCE had a sensitivity = 90%, specificity = 100%, positive predictive value = 100% and negative predictive value = 94% for the diagnosis of CD.CONCLUSION SBCE proved to be fundamental in the reclassification of patients with IBDU. Absence of significant inflammatory activity in the small intestine allowed exclusion of CD in 94% of cases. | Sara Monteiro Francisca Dias de Castro Pedro Boal Carvalho Bruno Rosa Maria Joao Moreira Rolando Pinho Miguel Mascarenhas Saraiva José Cotter | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，1： | 3 |
| 7 | A Probabilistic Displacement-based Vulnerability Assessment Procedure for Earthquake Loss Estimation显示文摘 | Helen Crowley Rui Pinho Julian J. Bommer | 2004 | Bulletin of Earthquake Engineering2004，，2： | 2 |
| 8 | Nicotinic cholinergic receptors in esophagus:Early alteration during carcinogenesis and prognostic value显示文摘AIM: To compare expression of nicotinic cholinergic receptors(CHRNs) in healthy and squamous cell carcinoma-affected esophagus and determine the prognostic value.METHODS: We performed RT-q PCR to measure the expression of CHRNs in 44 esophageal samples from healthy individuals and in matched normal surrounding mucosa, and in tumors from 28 patientsdiagnosed with esophageal squamous cell carcinoma(ESCC). Next, we performed correlation analysis for the detected expression of these receptors with the habits and clinico-pathological characteristics of all study participants. In order to investigate the possible correlations between the expression of the different CHRN subunits in both healthy esophagus and tissues from ESCC patients, correlation matrices were generated. Subsequently, we evaluated whether the detected alterations in expression of the various CHRNs could precede histopathological modifications during the esophageal carcinogenic processes by using receiver operating characteristic curve analysis. Finally, we evaluated the impact of CHRNA5 and CHRNA7 expression on overall survival by using multivariate analysis.RESULTS: CHRNA3, CHRNA5, CHRNA7 and CHRNB4, but not CHRNA1, CHRNA4, CHRNA9 or CHRNA10, were found to be expressed in normal(healthy) esophageal mucosa. In ESCC, CHRNA5 and CHRNA7 were overexpressed as compared with patient-matched surrounding non-tumor mucosa(ESCC-adjacent mucosa; P < 0.0001 and P = 0.0091, respectively). Positive correlations were observed between CHRNA3 and CHRNB4 expression in all samples analyzed. Additionally, CHRNB4 was found to be differentially expressed in the healthy esophagus and the normalappearing ESCC-adjacent mucosa, allowing for distinguishment between these tissues with a sensitivity of 75.86% and a specificity of 78.95%(P = 0.0002). Finally, CHRNA5 expression was identified as an independent prognostic factor in ESCC; patients with high CHRNA5 expression showed an increased overall survival, in comparison with those with low expression. The corresponding age- and tumor stage-adjusted hazard ratio was 0.2684(95%CI: 0.075-0.97, P = 0.0448).CONCLUSION: Expression of CHRNs is homogeneous along healthy esophagus and deregulated in ESCC, suggesting a pathogenic role for these receptors in ESCC development and progression. | Marina Chianello Nicolau Luis Felipe Ribeiro Pinto Pedro Nicolau-Neto Paulo Roberto Alves de Pinho Ana Rossini Tatiana de Almeida Simao Sheila Coelho Soares Lima | 2016 | World Journal of Gastroenterology2016，22，31： | 2 |
| 9 | Glycine max (L.) Merr., Vigna radiata L. and Medicago sativa L. sprouts: A natural source of bioactive compounds显示文摘 | Luís R. Silva Maria J. Pereira Jessica Azevedo Rui F. Gon?alves Patrícia Valent?o Paula Guedes de Pinho Paula B. Andrade | 2013 | Food Research International2013，，1： | 2 |
| 10 | Gastrointestinal stromal tumor: report of two unusual cases显示文摘 | Mário Rodrigues Montemor Neto Tiago Noguchi Machuca Renato Valmassoni Pinho Lucas Dan Yuasa Luiz Fernando Bleggi-Torres | 2004 | Virchows Archiv2004，，6： | 2 |
| 11 | Reduced Risk of Tuberculosis among Brazilian Patients with Advanced Human Immunodeficiency Virus Infection Treated with Highly Active Antiretroviral Therapy 显示文摘 | Santoro Lopes G De Pinho AM Harrison LH | 2002 | Clin Infect Dis2002，34，： | 1 |
| 12 | Assessing structural and functional ecosystem condition using leaf breakdown:studies on a polluted river显示文摘 | Pascoal C Pinho M Cassio F | 2003 | Freshwater Biology2003，48，： | 1 |
| 13 | Autologous fibroblast cul- ture in the repair of aging skin显示文摘 | Eca LP Pinto DG de Pinho AM | 2012 | Dermatol Surg2012，38，2： | 1 |
| 14 | Role of PBP1 in ceil division of Staphylococcus aureus 显示文摘 | Pereira S F F Henriques A O Pinho M G | 2007 | Bacteriology2007，189，9： | 1 |
| 15 | Computer Aided Rheological Design of Extrusion Dies for Profiles显示文摘 | Carneiro O S Nobrega J M Pinho F T | 2001 | Materials Processing Technology2001，114，： | 1 |
| 16 | Toxicological effects of hepatotoxins(Microcystins) on aquatic organisms 显示文摘 | JM Monserrat GLL Pinho JS Yunes | 2003 | Comments on Toxicology2003，，9： | 1 |
| 17 | Electromyographic activity in patients with temporomandibular disorders 显示文摘 | Pinho JC Caldas FM Moral M J | 2000 | J Oral Rehabil2000，27，11： | 1 |
| 18 | ATR-FTIR: studies of poly ( propylene oxide)/polybutadiene hi-soft segment urethane/urea membranes 显示文摘 | Queiroz D P De Pinho M N Dias C | 2003 | Macromolecules2003，36，11： | 1 |
| 19 | Aging effect on the reflectivity measurements of polychloroprene matrices containing carbon black and carbonyl-iron powder显示文摘 | Pinho M S Gregori M L Nunes R C R Soares B G | 2001 | Polymer Degradation and Stability2001，73，： | 1 |
| 20 | Gastrointestinal stromal tumor: report of two unusual cases显示文摘 | Mário Rodrigues Montemor Neto Tiago Noguchi Machuca Renato Valmassoni Pinho Lucas Dan Yuasa Luiz Fernando Bleggi-Torres | 2004 | Virchows Archiv2004，，6： | 1 |
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