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| 1 | Parkin promotes proteasomal degradation of p62: implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson's disease显示文摘 | Pingping Song Shanshan Li Hao Wu Ruize Gao Guanhua Rao Dongmei Wang Ziheng Chen Biao Ma Hongxia Wang Nan Sui Haiteng Deng Zhuohua Zhang Tieshan Tang Zheng Tan Zehan Han Tieyuan Lu Yushan Zhu Quan Chen | 2016 | Protein & Cell2016，7，2： | 8 |
| 2 | Compensation effects of coated cysteamine on meat quality, amino acid composition, fatty acid composition, mineral content in dorsal muscle and serum biochemical indices in finishing pigs offered reduced trace minerals diet显示文摘Dear Editor.Trace mineral elements(ME)and amino acids have been demonstrated to be essential bioelements in animal nutrition.If there is a deficiency in ME,a number of biological functions in animals may be affected,including physical growth,psychomotor development,and immunity.Supplementation of pig diets with ME is known to improve the animals'growth,reproduction,and their immunity against oxidative stress and cell damage. | Miaomiao Bai Hongnan Liu Kang Xu Xiaofeng Zhang Baichuan Deng Chengquan Tan Jinping Deng Pingping Bing Yulong Yin | 2019 | Science China(Life Sciences)2019，62，11： | 6 |
| 3 | Variations in silicate concentration affecting photosynthetic carbon fixation by spring phytoplankton assemblages in surface water of the Strait of Malacca显示文摘The Strait of Malacca (SoM), the world's busiest sea-route, is increasingly polluted as the rapid development of world trades, affecting phytoplankton primary productivity therein. The variations of surface phytoplankton biomass, size-structure and carbon fixation were investigated across the SoM during the spring period (May 4 to 9, 2011). Chlorophyll a concentration increased from 0.12 μg/L at the northwest entrance of the SoM to a maximal 0.63 μg/L at narrowest section, and decreased to 0.10 μg/L at the southeast entrance. Photosynthetic carbon fixation by phytoplankton coincided well with Chl a biomass, and increased from 10.8 to 22.3 μg C/(L d), then decreased to 9.21 μg C/(L d); while the carbon fixation rate showed an inverse pattern to the changes of Chl a, and decreased from 87.1 to 35.5 μg C/(μg Chl a d) and increased thereafter to 95.3 μg C/(μg Chla·d). Picophytoplankton cells (<3 μm) contributed to more than 60% and 50% of the total Chl a and carbon fixation at both the entry waters; while the contributions of pico-cells decreased sharply to the minimum of 18.3% and 27.5% at the narrowest part of the SoM. In particular, our results showed that the silicate concentration positively regulated Chl a biomass and carbon fixation, reflecting that the higher silicate favoured the growth of phytoplankton and thus led to higher primary production in this strait. | LI Gang LIN Qiang SHEN Pingping NI Guangyan SONG Xingyu WANG Shengfu FAN Yanzhi HUANG Liangmin TAN Yehui | 2013 | Acta Oceanologica Sinica2013，32，4： | 4 |
| 4 | Longitudinal patterns of spring-intermonsoon phytoplankton biomass,species compositions and size structure in the Bay of Bengal显示文摘Vertical distributions of phytoplankton biomass,compositions and size structure were investigated during the spring-intermonsoon (April 22 to 30) of 2010 along transact 10 N of the Bay of Bengal,northern Indian Ocean.Surface phytoplankton biomass (Chl a) was (0.065 ± 0.009) μg/L,being greater than 80% of which was contributed by pico-phytoplankton (<3 μm).The Chl a concentration vertically increased to the maximal values at deep chlorophyll maximum (DCM) layer that shoaled eastwards from 75 to 40 m.The Chl a biomass at DCM layer generally varied between 0.2 and 0.4 μg/L,reaching the maximum of 0.56 μg/L with micro-phytoplankton cells (>20 μm) accounting for 58% and nano-(3-20 μm) or pico-cells for 15% and 27%,respectively.In particular,the cells concentration coupling well with phosphate level was observed at middle layer (75-100 m) of 87 to 89 E,dominated by micro-cells diatoms (e.g.,Chaetoceros atlanticus v.neapolitana,Chaetoceros femur and Pseudonitzschia sp.) and cyanobacteria (i.e.,Trichodesmium hildebrandtii),with the cells concentration reached as high as 4.0 × 10 4 and 4.3 × 10 4 cells/L.At the rest of the transact however,dinoflagellates (e.g.,Amphisdinium carterae and Prorocentrum sp.) were the dominant species,with the cells concentration varying from 0.3 × 10 3 to 6.8 × 10 3 cells/L.Our results also indicate that the regulation of large cells (micro-,nano-) on phytoplankton biomass merely occurred at DCM layer of the Bay. | LI Gang KE Zhixin LIN Qiang NI Guangyan SHEN Pingping LIU Huaxue YIN Jianqiang LI Kaizhi HUANG Liangmin TAN Yehui | 2012 | Acta Oceanologica Sinica2012，31，2： | 2 |
| 5 | A murine model for human immune thrombocytopenic purpura and comparative analysis of multiple gene expression in bone marrow and spleen显示文摘Homeostasis of platelet number in human and other mammals is well maintained for prevention of minor bleeding and for other immunological functions,but the exact molecular mechanism responsible for immune thrombocytopenic purpura(ITP) has not been fully understood.In an effort to identify genetic factors involved in initiation of platelet production in response to bleeding injury or platelet destruction,we have successfully generated an animal model of human ITP via intraperitoneal injection of anti-platelet antibody into the Balb/c mouse.Platelet counts were dropped dramatically in animals that received antibody injection within 4 h,maintained at the mini-mum level for a period of 44 h,started to rebound after 48 h,and reached to the maximum at 144 h(6 days).Final homeostasis reached at approximately 408 h(17 days),following a minor cycle of platelet number fluctuation.Using semi-quantitative RT-PCR,we assessed and compared mRNA level of CD41,c-myb,c-mpl,caspase-3,caspase-9,GATA-1,and Bcl-xl in bone marrow and spleen.Alteration of mRNA expression was correlated with the change of platelet level,and an inverse relationship was found for expression of the genes between bone marrow and spleen.No transcription was detectable for any of the seven genes in bone marrow at the time when platelet number reached the maximum(144 h).In contrast,mRNA transcripts of the seven genes were found to be at the highest level in spleen tissue.This is the first study of simultaneous detection of multiple platelet related genes in a highly reproducible ITP animal model.Our results provided the supportive evidence that expression of the above seven genes are more related to negative regulation of platelet number in spleen tissue,at least in the model animals. | Hong Wei Xinchun Ding Jiangong Ren Ka Liu Pingping Tan Daquan Li Runlin Z. Ma | 2008 | Journal of Genetics and Genomics2008，35，11： | 2 |
| 6 | Short circuit current limiter in ac network显示文摘 | Wu Zhaolin Chen Pingping Tan Lingyun | 2001 | Journal of Zhejiang University(SCIENCE)2001，2，1： | 1 |
| 7 | Short circuit current limiterinACnetwork显示文摘 | Wu Zhaolin Chen Pingping Tan Lingyun | 2001 | Journal of Zhejiang University (Science)2001，2，1： | 1 |
| 8 | Metabolomic analysis of the response of growing pigs to dietary l-arginine supplementation显示文摘 | Qinghua He Xiangfeng Kong Guoyao Wu Pingping Ren Huiru Tang Fuhua Hao Ruilin Huang Tiejun Li Bie Tan Peng Li Zhiru Tang Yulong Yin Yongning Wu | 2009 | Amino Acids2009，，1： | 1 |
| 9 | Short circuit current limiter in ac network显示文摘 | Wn Zhaolin Chen Pingping Tan Lingyun | 2001 | Journal of Zhejiang University (SCIENCE)2001，2，1： | 1 |
| 10 | Treatment of hepatitis C virus core-positive hepatocytes with the transfer of recombinant caspase-3 using the 2~,5^-oligoadenylate synthetase gene promoter显示文摘丙肝病毒(HCV ) 感染在全世界是肝相关的病态和死亡的一个领先的原因。没有可得到的疫苗,当前的治疗部分仅仅是有效的。因为 HCV 感染仅仅少数 hepatocytes,我们假设了 apoptosis 的那正式就职可能是为丙肝的处理的一条有希望的途径。在现在的学习,因为它有能力导致独立于开始者 caspases 的 apoptosis, recombinant caspase-3 基因(re-caspase-3 ) 被使用。一个 HCV 特定的倡导者被要求在感染 HCV 的房间调整细胞毒素的 caspase-3 表示。HCV 核心蛋白质罐头明确地激活 2,5-oligoadenylate 合成酶(美洲国家组织) ,这被报导了在人的 hepatocytes 的基因倡导者。因此,我们构造了在 OAS 基因倡导者(pGL3-OAS-re-caspase-3 ) 下面由 re-caspase-3 组成的表示向量然后在 HCV 核心积极的肝房间上调查了它的效果。pGL3-OAS-re-caspase-3 构造在 HCV 核心积极的肝房间,然而并非在正常的肝房间导致了 apoptosis,这被发现。这些结果强烈建议在 OAS 倡导者下面的 re-caspase-3 基因的转移是为 HCV 感染的处理的一条新奇指向途径。 | Ying Wang Shanshan Mao Bo Li Pingping Tan Deyun Feng Jifang Wen | 2009 | Acta Biochimica et Biophysica Sinica2009，41，7： | 1 |
| 11 | Short circuit current limiter in AC network显示文摘 | Wu Zhaolin Chen Pingping Tan Lingyun | 2001 | Journal of Zhejiang University (Science) (English Version)2001，2，1： | 1 |
| 12 | Short circuit current limiter in ac network显示文摘 | Wu Zhaolin Chen Pingping Tan Lingyun | 2001 | Journal of Zhejiang University (SCIENCE)2001，2，1： | 1 |
| 13 | Metabolomic analysis of the response of growing pigs to dietary l-arginine supplementation显示文摘 | Qinghua He Xiangfeng Kong Guoyao Wu Pingping Ren Huiru Tang Fuhua Hao Ruilin Huang Tiejun Li Bie Tan Peng Li Zhiru Tang Yulong Yin Yongning Wu | 2009 | Amino Acids2009，，1： | 1 |
| 14 | Time-varying baseline error correction method for ground-based micro-deformation monitoring radar显示文摘In recent years, ground-based micro-deformation monitoring radar has attracted much attention due to its excellent monitoring capability. By controlling the repeated campaigns of the radar antenna on a fixed track, ground-based micro-deformation monitoring radar can accomplish repeat-pass interferometry without a space baseline and thus obtain highprecision deformation data of a large scene at one time. However, it is difficult to guarantee absolute stable installation position in every campaign. If the installation position is unstable, the stability of the radar track will be affected randomly, resulting in time-varying baseline error. In this study, a correction method for this error is developed by analyzing the error distribution law while the spatial baseline is unknown. In practice, the error data are first identified by frequency components, then the data of each one-dimensional array(in azimuth direction or range direction) are grouped based on numerical distribution period, and finally the error is corrected by the nonlinear model established with each group.This method is verified with measured data from a slope in southern China, and the results show that the method can effectively correct the time-varying baseline error caused by rail instability and effectively improve the monitoring data accuracy of groundbased micro-deformation radar in short term and long term. | LEI Tianjie WANG Jiabao HUANG Pingping TAN Weixian QI Yaolong XU Wei ZHAO Chun | 2022 | Journal of Systems Engineering and Electronics2022，33，4： | 0 |
| 15 | 中国北京地区部分医院患者疼痛现状调查(英文)显示文摘Objective:This study aimed to survey the characteristics and treatments of cancer pain in Beijing hospitals,China.Methods:At 20:00 on December 22,2009,there conducted a questionnaire survey in 2238 patients with malignant tumors of 26 hospitals in Beijing,and the survey results were statistically analyzed.Results:The 531 cases in 2238 patients had pained and 121 cases (22.79%) had outbreak pain with one week.At 20:00 on December 22,2009,199 cases (38%) in the above-mentioned 531 pain patients suffered the moderate to severe pain (pain scores ≥ 4).The number of pain (pain scores ≥ 4) patients in the consecutive three days from December 20 to December 22 were 150.Conclusion:In the 531 cancer pain patients of the surveyed hospitals,38% of the patients were not satisfied with the pain control.Doctors believed that the main reason for pain not controlled was the non-standard treatment,but patients considered to be afraid of addiction. | Shikai Wu Fang Li Pingping Li Jian Luo Xiaoming Wu Heling Shi Xiaohong Ning Yufei Yang Huangying Tan Ping Yang Guangqing Zhu Jianhua Zhu Guoqing Liao Huoming Chen Dapeng Lv Ye Fang Hong Dai Xiaoming Xi Xiuhua Li Yuan Qin Li Feng Su Wang Xiaoyan Chen Hongyong Wang Hongyan Li Duanqi Liu | 2012 | The Chinese-German Journal of Clinical Oncology2012，11，6： | 0 |
| 16 | Genetic study on the behavior of honeybees influenced by polyandry system显示文摘Within a honeybee population, due to polyandry, there are super-sister and half-sister relations, thus many sub-families exist. For the Chinese honeybee (Apis cerana cerana F.) a phylogenetic dendrogram has been constructed in which 4 sub-families are clustered based on DNA fingerprint patterns. And it has been observed that each kind of workers is distributed to several different sub-families. | Yan Ouyang Liming Wu Feng Jin Wei Shi Pingping Tan Qinhua Bai Xianshu Liu | 1999 | Chinese Science Bulletin1999，44，20： | 0 |
| 17 | Frequency Tuning Feature of a Reditron Oscillator显示文摘We report some experimental results which confirm the theoretical analysis of the tuning feature of a reditron oscillator.Here,we produce high power microwave at 10 GHz,and the tuning range of the reditron is 8-13.32 GHz which is controlled by changing both the voltage and the anode-to-cathode separation.We also report a measurement method of the anode-to-cathode distance. | LING Genshen LI Xiangsheng WANG Yong LI Chuanlu TAN Qimei LI Pingping | 1995 | Chinese Physics Letters1995，12，8： | 0 |
| 18 | Self-frequency-conversion nanowire lasers显示文摘Semiconductor nanowires(NWs)could simultaneously provide gain medium and optical cavity for performing nanoscale lasers with easy integration,ultracompact footprint,and low energy consumption.Here,we report Ⅲ-Ⅴsemiconductor NW lasers can also be used for self-frequency conversion to extend their output wavelengths,as a result of their non-centrosymmetric crystal structure and strongly localized optical field in the NWs.From a GaAs/In0.16Ga0.84As core/shell NW lasing at 1016 nm,an extra visible laser output at 508 nm is obtained via the process of second-harmonic generation,as confirmed by the far-field polarization dependence measurements and numerical modeling.From another NW laser with a larger diameter which supports multiple fundamental lasing wavelengths,multiple self-frequency-conversion lasing modes are observed due to second-harmonic generation and sum-frequency generation.The demonstrated self-frequency conversion of NW lasers opens an avenue for extending the working wavelengths of nanoscale lasers,even to the deep ultraviolet and THz range. | Ruixuan Yi Xutao Zhang Chen Li Bijun Zhao Jing Wang Zhiwen Li Xuetao Gan Li Li Ziyuan Li Fanlu Zhang Liang Fang Naiyin Wang Pingping Chen Wei Lu Lan Fu Jianlin Zhao Hark Hoe Tan Chennupati Jagadish | 2022 | Light(Science & Applications)2022，11，6： | 0 |
| 19 | Plant above-ground biomass and litter quality drive soil microbial metabolic limitations during vegetation restoration of subtropical forests显示文摘Changes in litter quality(carbon:nitrogen,C:N)and above-ground biomass(AGB)following vegetation restoration significantly impact soil physicochemical properties,yet their effects on soil microbial metabolic limitations remain unclear.We measured litter quality,AGB,soil physicochemical properties,and extracellular enzyme activity(EEA)along a vegetation restoration gradient(7,14,49,70 years,and nearly climax evergreen broadleaved forests)in southern China.We also evaluated soil microbial metabolic limitations by a vector analysis of the EEA.Results revealed the soil microbial metabolisms were co-limited by C and phosphorus(P).The microbial C limitation initially decreased(before 14 years)and then increased,while the microbial P limitation initially increased(before 49 years)and then decreased.Partial least squares path modeling(PLS-PM)showed that the microbial C limitation was mainly attributed to microbial C use efficiency induced by litter quality,suggesting that microorganisms may transfer cellular energy between microbial growth and Cacquiring enzyme production.The microbial P limitation was primarily correlated with AGB-driven change in soil elements and their stoichiometry,highlighting the importance of nutrient stoichiometry and balance in microbial metabolism.The shifts between microbial C and P limitations and the strong connections of plant–soil-microbe processes during vegetation restoration revealed here will provide us with helpful information for optimal management to achieve forest restoration success. | Shuo Zhang Ying-Ping Wang Xi Fang Jinlei Chen Nannan Cao Pingping Xu Mengxiao Yu Xin Xiong Xiangping Tan Qi Deng Junhua Yan | 2023 | Soil Ecology Letters2023，5，2： | 0 |
| 20 | Separation and Identification of Stage-specific Proteins in Pistillate Flowers of Mulberry显示文摘In order to excavate the function genes of stage-specific proteins in the development process of mulberry pistillate flowers,using fruit mulberry cultivar‘Da 10’as experiment material,two-dimensional electrophoresis and mass-spectrometric technology were used to investigate specifically expressed proteins of mulberry pistillate flowers in different flowering periods.The results showed that 471±4,450±15 and 446±14 protein spots were determined in mulberry pistillate flowers at full-bloom stage,initial flowering stage and terminal flowering stage respectively,including nine protein spots with characteristics of stage-specific expression and clear electrophoretic bands..By mass spectrometry analysis,database retrieval and bioinformatics analysis,five components were successfully identified as lactoylglutathione lyase-like protein,perchloric acid soluble translation inhibitor protein,ubiquitin-conjugating enzyme 1 like protein,putative ethylene response protein and 3-hydroxyisobutyrate dehydrogenase,which were involved in stress resistance reaction,protein catabolism,signal transduction,glycometabolism and other biological processes in plants,which indicated that these proteins might play an important biological function in the normal development and pollination fertilization of mulberry pistillate flowers. | Ruihe NIU Yuanyuan CHEN Pingping ZHANG Wei QI Biping ZHENG Jianzhong TAN | 2013 | Agricultural Biotechnology2013，2，6： | 0 |
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