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		题名	作者	年代	出处	被引量
	1	Ultrasound/Microbubble Enhances Foreign Gene Expression in ECV304 Cells and Murine Myocardium显示文摘Although viral vectors are efficient systems to transfer foreign genes into cells or target tissues, safety issues remain in relation to human gene therapy. Microbubbles currently used as ultrasound contrast agents have been applied in transfection of genes. This study was designed to test the transfection efficiency and the expression of exogenous gene mediated by ultrasound irradiation enhanced air filled albumin microbubbles in ECV304 cell line in vitro and the heart of the mouse in vivo. Air filled microbubbles (2.0– 4.0 μm in diameter) were created by sonicating the mixture of human albumin, glucose, mannitol and special additive that was designed for stabilization. Plasmid DNA loading the reporter geneswas gently mixed with microbubbles. The mixture of plasmid DNA and microbubbles was administrated to cultured ECV304 cells and BALB/c mice (tail vein injection) under different ultrasound/microbubble conditions, and then the trans- fection and expression efficiency were examined. The results both in vivo and in vitro demonstrated that microbubble with ultrasound irradiation could significantly elevate the exogenous gene expression as compared with microbubble or ultrasound only. Overall, the present study showed that the ultrasound-target microbubble destruction method enhanced the exogenous gene expression in vivo and in vitro, and provided a gene therapy way not only efficient but also easy to be manipulated and carried out in clinical.	DongpingGUO XiaoyuLI PingSUN ZhiguangWANG XiuyingCHEN QiCHEN LemingFAN BinZHANG LizhengSHAO XiaorongLI	2004	Acta Biochimica et Biophysica Sinica2004，36，12：	12
	2	Energy and tourism in Hawaii显示文摘	Natalia Tabatchnaia-Tamirisa Matthew K. Loke PingSun Leung Ken A. Tucker	1997	Annals of Tourism Research1997，，2：	1
	3	Economics of offshore aquaculture of Pacific threadfin ( Polydactylus sexfilis ) in Hawaii显示文摘	Lotus E. Kam PingSun Leung Anthony C. Ostrowski	2003	Aquaculture2003，，1：	1
	4	The Normalized Revealed Comparative Advantage Index 显示文摘	Yu Run Cai Junning Leung Pingsun	2009	The Annals of Regional Science2009，43，：	1
	5	Comparative economics of shrimp farming in Asia显示文摘	Pingsun Leung Bith-Hong Ling	1998	Aquaculture1998，164，：	1
	6	Use of strain imaging in detecting segmental dysfunction in patients with hypertrophic cardiomyopathy 显示文摘	Hua Yang Jing Pingsun Harry M Lever	2003	J Am Soc Echocardiogr2003，16，3：	1
	7	The Normalized Revealed Comparative Advantage Index显示文摘	Run Yu Junning Cai Pingsun Leung	2009	Ann Reg Sci2009，，2009：	1
	8	TheNormalized Revealed Comparative Advantage Index 显示文摘	Yu Run Junning Cai PingSun Leung	2009	The Annals of Regional Science2009，43，1：	1
	9	The normalized revealed comparative advantage index 显示文摘	Run Yu Junning Cai PingSun Leung	2009	The Annals of Regional Science2009，，43：	1
	10	The normalized re- vealedcomparative advantage index显示文摘	Yu Run JunningCai PingSun Leung	2009	The Annals of Regional Science2009，43，1：	1
	11	Energy and Tourism in Hawaii 显示文摘	Natalia Tabatchnaia-Tamirisa Matthew Loke PingSun Leung	1997	Annals of Tourism Research1997，24，2：	1
	12	Productive Efficiency of the Swine Industry in Hawaii: Stochastic Frontier vs. Data Envelopment Analysis显示文摘	Khem R. Sharma Pingsun Leung Halina M. Zaleski	1997	Journal of Productivity Analysis1997，，4：	1
	13	Technical efficiency of the longline fishery in Hawaii:an application of a stochastic production frontier 显示文摘	Sharma Khem R Leung pingsun	1999	Marine Resource Economics1999，，13：	1
	14	The Normalized Revealed Comparative Advantage Index显示文摘	Run Yu Junning Cai PingSun Leung		0，，43：	1
	15	Energy and Tourism in Hawaii显示文摘	Natalia Tabachnaia-Tamirisa Mattew K Loke PingSun Leung	1997	Annals of Tourism Research1997，，2：	1
	16	Energy and tourism in Hawaii显示文摘	Natalia Tabatchnaia-Tamirisa Matthew K. Loke PingSun Leung Ken A. Tucker	1997	Annals of Tourism Research1997，，2：	1
	17	Energy and tourism in Hawaii显示文摘	] Natalia Tabatchnaia-Tamirisa Matthew K Loke PingSun Leung et al	1997	Annals of Tourism Research1997，24，2：	1
	18	Estimating economic impacts from tourism显示文摘	Deying Zhou John F. Yanagida Ujjayant Chakravorty PingSun Leung	1996	Annals of Tourism Research1996，，1：	1
	19	“ The Normalized Revealed Comparative Advantage Index” 显示文摘	Yu R un Junning Cai PingSun Leung	2009	The Annals ofRegional Science2009，43，1：	1

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