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您的检索式：作者名="Ping Chook"
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| 1 | Effects of resistance training on cardiovascular health in non-obese active adolescents显示文摘AIM:To determine the benefits of a 10-wk resistance training programme on cardiovascular health in nonobese and active adolescents.METHODS:This is a pragmatic randomised controlled intervention.The study was carried out in a Hong Kong Government secondary school.Thirty-eight lean and active boys and girls were randomised to either the resistance training group or the control group.Students in the resistance training group received in-school 10-wk supervised resistance training twice per week,with each session lasting 70 min.Main outcome measures taken before and after training included brachial endothelial dependent flow-mediated dilation,body composition,fasting serum lipids,fasting glucose and insulin,high sensitive C-reactive protein,24-h ambulatory blood pressure and aerobic fitness.RESULTS:The only training related change was in endothelial dependent flow-mediated dilation which increased from 8.5%to 9.8%.A main effect of time and an interaction(P<0.005) indicated that this improvement was a result of the 10-wk resistance training.Main effects for time(P<0.05) in a number of anthropometric,metabolic and vascular variables were noted;however,there were no significant interactions indicating the change was more likely an outcome of normal growth and development as opposed to a training effect.CONCLUSION:Ten weeks of resistance training in school appears to have some vascular benefit in active,lean children. | Clare Chung-Wah Yu Alison Mary McManus Hung-Kwan So Ping Chook Chun-Ting Au Albert Martin Li Jack Tat-Chi Kam Raymond Chi-Hung So Christopher Wai-Kei Lam Iris Hiu-Shuen Chan Rita Yn-Tz Sung | 2016 | World Journal of Clinical Pediatrics2016，5，3： | 1 |
| 2 | Orlistat improves endothelial function in obese adolescents: A randomised trial显示文摘 | Clare CW Yu Albert M Li Karly OW Chan Ping Chook Jack TC Kam Chun T Au Raymond CH So Rita YT Sung Alison M McManus | 2013 | J Paediatr Child Health2013，，11： | 1 |
| 3 | Long-term improvement in homocysteine levels and arterial endothelial function after 1-year folic acid supplementation显示文摘 | Kam S Woo Ping Chook Lindy L.T Chan Alice S.P Cheung Wing H Fung M.u Qiao Yvette I Lolin G.N Thomas John E Sanderson Con Metreweli David S Celermajer | 2002 | The American Journal of Medicine2002，，7： | 1 |
| 4 | Crocodile blood supplementation protect svascular function in diabetic mice显示文摘Cardiovascular disease is a major cause of mortality in diabetic patients due to the heightened oxidative stress and pro-inflammatory state in vascular tissues.Effective approaches targeting cardiovascular health for diabetic patients are urgently needed.Crocodile blood,an emerging dietary supplement,was suggested to have anti-oxidative and anti-inflammatory effects in vitro,which have yet to be proven in animal models.This study thereby aimed to evaluate whether crocodile blood can protect vascular function in diabetic mice against oxidation and inflammation.Diabetic db/db mice and their counterparts db/m+mice were treated daily with crocodile blood soluble fraction(CBSF)or vehicle via oral gavage for 4 weeks before their aortae were harvested for endothelium-dependent relaxation(EDR)quantification using wire myograph,which is a well-established functional study for vascular function indication.Organ culture experiments culturing mouse aortae from C57BL/6 J mice with or without IL-1βand CBSF were done to evaluate the direct effect of CBSF on endothelial function.Reactive oxygen species(ROS)levels in mouse aortae were assessed by dihydroethidium(DHE)staining with inflammatory markers in endothelial cells quantified by quantitative polymerase chain reaction(qPCR).CBSF significantly improved deteriorated EDR in db/db diabetic mice through both diet supplementation and direct culture,with suppression of ROS level in mouse aortae.CBSF also maintained EDR and reduced ROS levels in mouse aortae against the presence of pro-inflammatory IL-1β.Under the pro-inflammatory state induced by IL-1β,gene expressions of inflammatory cytokines were downregulated,while the protective transcripts UCP2 and SIRT6 were upregulated in endothelial cells.Our study suggests a novel beneficial effect of crocodile blood on vascular function in diabetic mice and that supplementation of diet with crocodile blood may act as a complementary approach to protect against vascular diseases through anti-oxidation and anti-inflammation in diabetic patients. | Chui Yiu Bamboo Chook Francis M.Chen Gary Tse Fung Ping Leung Wing Tak Wong | 2021 | Food Production, Processing and Nutrition2021，3，1： | 0 |
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