|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The Genome of Medicinal Plant Macleaya cordata Provides New Insights into Benzylisoquinoline Alkaloids Metabolism显示文摘在动物农业和药的抗菌素的 overuse 引起了一系列潜在的威胁到公共健康。Macleaya cordata 是从 Papaveraceae 家庭的药用的植物种,提供为抗菌剂的制造的一个安全资源为家畜喂添加剂。从 M. 的活跃成分 ? cordata 被知道包括 benzylisoquinoline 碱(偏爱) 象 sanguinarine (圣) 和 chelerythrine (CHE ) 那样的 ?,而是他们的新陈代谢的小径还得在这非模型植物被学习。在 M. 的圣和 CHE 的活跃生合成 ? cordata 被喂 13标记 C 的酷氨酸。为了增加,推进卓见,我们 de novo 定序 M 的整个染色体。cordata,第一从 Papaveraceae 家庭被定序。M.? 盖住 378 Mb 的 cordata 染色体与 43.5%being 编码 22,328 预言的编码蛋白质的基因 transposable 元素。作为基础 eudicot 的一个成员, M.? cordata 染色体缺乏 ? 发生在几乎所有 eudicots 的 paleohexaploidy 事件。从 genomics 数据, 16 的一个完全的集合 ? 新陈代谢 ? 为圣和 CHE 生合成的基因被检索,并且 14 项他们的生物化学的活动被验证。这些 genomics 和新陈代谢的数据在 M. 显示出保存 BIA 新陈代谢的小径 ? cordata 并且由庄稼改进或微生物引起的小径重建为圣和 CHE 的未来生产提供知识基础。 | Xiubin Liu Yisong Liu Peng Huang Yongshuo Ma Zhixing Qing Qi Tang Huifen Cao Pi Cheng Yajie Zheng Zejun Yuan Yuan Zhou Jinfeng Liu Zhaoshan Tang Yixiu Zhuo Yancong Zhang Linlan Yu Jialu Huang Peng Yang Qiong Peng dinbo Zhang Wenkai Jiang Zhonghua Zhang Kui Lin Dae-Kyun Ro Xiaoya Chen Xingyao Xiong Yi Shang Sanwen Huang Jianguo Zeng | 2017 | Molecular Plant2017，10，7： | 19 |
| 2 | A Chromosome-Scale Genome Assembly of Paper Mulberry(Bmussonetia papyrifera)Provides New Insights into Its Forage and Papermaking Usage显示文摘Paper mulberry(Broussonetia papyrifera)is a well-known woody tree historically used for Cai Lun papermaking,one of the four great inventions of ancient China.More recently,Paper mulberry has also been used as forage to address the shortage of feedstuff because of its digestible crude fiber and high protein contents.In this study,we obtained a chromosome-scale genome assembly for Paper mulberry using integrated approaches,including Illumina and PacBio sequencing platform as well as Hi-C,optical,and genetic maps.The assembled Paper mulberry genome consists of 386.83 Mb,which is close to the estimated size,and 99.25%(383.93 Mb)of the assembly was assigned to 13 pseudochromosomes.Comparative genomic analysis revealed the expansion and contraction in the flavonoid and lignin biosynthetic gene families,respectively,accounting for the enhanced flavonoid and decreased lignin biosynthesis in Paper mulberry.Moreover,the increased ratio of syringyl-lignin to guaiacyl-lignin in Paper mulberry underscores its suitability for use in medicine,forage,papermaking,and barkcloth making.We also identified the rootassociated microbiota of Paper mulberry and found that Pseudomonas and Rhizobia were enriched in its roots and may provide the source of nitrogen for its stems and leaves via symbiotic nitrogen fixation.Collectively,these results suggest that Paper mulberry might have undergone adaptive evolution and recruited nitrogen-fixing microbes to promote growth by enhancing flavonoid production and altering lignin monomer composition.Our study provides significant insights into genetic basis of the usefulness of Paper mulberry in papermaking and barkcloth making,and as forage.These insights will facilitate further domestication and selection as well as industrial utilization of Paper mulberry worldwide. | Xianjun Peng Hui Liu Peilin Chen Feng Tang Yanmin Hu Fenfen Wang Zhi Pi Meiling Zhao Naizhi Chen Hui Chen Xiaokang Zhang Xueqing Yan Min Liu Xiaojun Fu Guofeng Zhao Pu Yao Lili Wang He Dai Xuming Li Wei Xiong Wencai Xu Hongkun Zheng Haiyan Yu Shihua Shen | 2019 | Molecular Plant2019，12，5： | 18 |
| 3 | A nano-cocrystal strategy to improve the dissolution rate and oral bioavailability of baicalein显示文摘Baicalein(BE) is one of the main active flavonoids representing the variety of pharmacological effects including anticancer, anti-inflammatory and cardiovascular protective activities, but it's very low solubility, dissolution rate and poor oral absorption limit the therapeutic applications. In this work, a nano-cocrystal strategy was successfully applied to improve the dissolution rate and bioavailability of BE. Baicalein-nicotinamide(BE-NCT) nanococrystals were prepared by high pressure homogenization and evaluated both in vitro and in vivo. Physical characterization results including scanning electron microscopy, dynamic light scattering, powder X-ray diffraction and differential scanning calorimetry demonstrated that BE-NCT nano-cocrystals were changed into amorphous state with mean particle size of 251.53 nm. In the dissolution test, the BE-NCT nano-cocrystals performed 2.17-fold and 2.54-fold enhancement than BE coarse powder in FaSSIF-V2 and FaSSGF. Upon oral administration, the integrated AUC0-t of BE-NCT nano-cocrystals(6.02-fold) was significantly higher than BE coarse powder(1-fold), BE-NCT cocrystals(2.87-fold) and BE nanocrystals(3.32-fold). Compared with BE coarse powder, BE-NCT cocrystals and BE nanocrystals, BENCT nano-cocrystals possessed excellent performance both in vitro and in vivo evaluations.Thus, it can be seen that nano-cocrystal is an appropriate novel strategy for improving dissolution rate and bioavailability of poor soluble natural products such as BE. | Jiaxin Pi Shuya Wang Wen Li Dereje Kebebe Ying Zhang Bing Zhang Dongli Qi Pan Guo Nan Li Zhidong Liu | 2019 | Asian Journal of Pharmaceutical Sciences2019，14，2： | 12 |
| 4 | Cortical plasticity and nerve regeneration after peripheral nerve injury显示文摘With the development of neuroscience, substantial advances have been achieved in peripheral nerve regeneration over the past decades. However, peripheral nerve injury remains a critical public health problem because of the subsequent impairment or absence of sensorimotor function. Uncomfortable complications of peripheral nerve injury, such as chronic pain, can also cause problems for families and society. A number of studies have demonstrated that the proper functioning of the nervous system depends not only on a complete connection from the central nervous system to the surrounding targets at an anatomical level, but also on the continuous bilateral communication between the two. After peripheral nerve injury, the interruption of afferent and efferent signals can cause complex pathophysiological changes, including neurochemical alterations, modifications in the adaptability of excitatory and inhibitory neurons, and the reorganization of somatosensory and motor regions. This review discusses the close relationship between the cerebral cortex and peripheral nerves. We also focus on common therapies for peripheral nerve injury and summarize their potential mechanisms in relation to cortical plasticity. It has been suggested that cortical plasticity may be important for improving functional recovery after peripheral nerve damage. Further understanding of the potential common mechanisms between cortical reorganization and nerve injury will help to elucidate the pathophysiological processes of nerve injury, and may allow for the reduction of adverse consequences during peripheral nerve injury recovery. We also review the role that regulating reorganization mechanisms plays in functional recovery, and conclude with a suggestion to target cortical plasticity along with therapeutic interventions to promote peripheral nerve injury recovery. | Ci Li Song-Yang Liu Wei Pi Pei-Xun Zhang | 2021 | Neural Regeneration Research2021，16，8： | 12 |
| 5 | Predictive value of serum uric acid on cardiovascular disease and all-cause mortality in urban Chinese patients显示文摘背景在尿酸(SUA ) 铺平的增加的浆液和心血管的风险之间的协会被辩论十年了。几大研究规定了在心血管的疾病(CVD ) 或脑血管的疾病关于提高的 SUA 层次的临床的意义冲突结果。这研究的目的从 56 ~ 95 年在年龄的 3570 个住院病人是调查在 SUA 和 CVD 和所有原因死亡和他们的潜在的诊断 value.Methods A 之间的关系全部的(平均数(67. | WU Yong-quan LI Jue XU Yuan-xi WANG Yong-liang LUO Ying-yi HU Da-yi LIU Wei-jing YANG Ming PI Lin WANG Ming-sheng WANG Ji-yun ZHAO Shu-mei LI Mei-jing | 2010 | Chinese Medical Journal2010，，11： | 11 |
| 6 | Analysis of Low-polar Ginsenosides in Steamed Panax Ginseng at High-temperature by HPLC-ESI-MS/MS显示文摘A high performance liquid chromatography coupled with electrospray ionization-tandem mass spectrome try(HPLC-ESI-MS/MS) method was developed for the analysis and identification of ginsenosides in the extracts of raw Panax ginseng(RPG) and steamed Panax ginseng at high temperatures(SPGHT). A total of 25 ginsenosides were extracted include of which 10 low-polar ginsenosides, such as ginsenosides F4, Rk3, Rh4, 20S-Rg3, 20R-Rg3 and so on, were identified according to their HPLC retention time and MS/MS data. The results indicated that the low polar ginsenosides were seldom found in RPG. For the exploration of the transformation pattern of the ginsenosides in steam processing, the standards of ginsenosides Re, Rg1, Rb1, Rc, Rb2, Rb3 and Rd were selected and hydrolyzed at a temperature of 120 oC. The results show that these polar ginsenosides can be converted to low-polar ginsenosides such as Rg2, Rg6, F4, Rk3 and Rg5 by hydrolyzing the sugar chains. | ZHANG Yu-chi1,2, PI Zi-feng1, LIU Chun-ming2, SONG Feng-rui1, LIU Zhi-qiang1 and LIU Shu-ying1 1. Changchun Center of Mass Spectrometry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China 2. Central Laboratory, Changchun Normal University, Changchun 130032, P. R. China | 2012 | Chemical Research in Chinese Universities2012，28，1： | 9 |
| 7 | Density-based trajectory outlier detection algorithm显示文摘With the development of global position system(GPS),wireless technology and location aware services,it is possible to collect a large quantity of trajectory data.In the field of data mining for moving objects,the problem of anomaly detection is a hot topic.Based on the development of anomalous trajectory detection of moving objects,this paper introduces the classical trajectory outlier detection(TRAOD) algorithm,and then proposes a density-based trajectory outlier detection(DBTOD) algorithm,which compensates the disadvantages of the TRAOD algorithm that it is unable to detect anomalous defects when the trajectory is local and dense.The results of employing the proposed algorithm to Elk1993 and Deer1995 datasets are also presented,which show the effectiveness of the algorithm. | Zhipeng Liu Dechang Pi Jinfeng Jiang | 2013 | Journal of Systems Engineering and Electronics2013，24，2： | 9 |
| 8 | No association between low-dose reserpine use and depression in older hypertensive patient: result of a multicenter, cross-sectional study显示文摘Background Reserpine is currently used by millions of Chinese hypertensive patients, in spite of the continued concern of its depressogenic effect, even when used in low dose. This study aimed to investigate the association between low-dose reserpine use and depression in older Chinese hypertensive patient. Methods In this cross-sectional, case-control study, we recruited patient aged 60 years or over who had regularly taken one or two tables of “compound reserpine and triamterene tablets (CRTTs)” for more than one year (reserpine user) from 26 community health centers located in 10 provinces in China. For each patient who took CRTTs, we selected an age (within five years) and sex matched hypertensive patient who had never taken any drugs containing reserpine (non-reserpine user) as control. Depressive symptoms were evaluated using a Chinese depression scale adapted from the Zung Self-Rating Depression Scale. Demographic, clinical data and laboratory examination results within six months were collected. Results From August 2018 to December 2018, 787 reserpine user and 787 non-reserpine user were recruited. The mean age of all study subjects was 70.3 years, with about equal numbers of males and females. The mean depression score was 40.4 in reserpine users and 40.6 in non-reserpine users (P = 0.7). The majority of study subject had a depression score < 53 (87.6% in reserpine users and 88.2% in non-reserpine users, respectively). There were no significant differences in the prevalence of mild, moderate or severe depression in reserpine users and non-reserpine users. Conclusions There is no association between low-dose reserpine use and depression in older hypertensive patient. The role of reserpine in the treatment and control of hypertension should be reconsidered;and further studies, especially randomized, controlled clinical trials to compare efficacy and safety of reserpine and other widely recommended anti-hypertensive agents are needed. | Guo-Hua ZHU Xi-Peng SUN Jing LI Lin PI Hai-Qin TANG Hai-Qing GAO Hong-Liang CONG Peng QU Xin-Zheng LU Xin-Jun ZHANG Luo-Sha ZHAO Yi-Fang GUO Dong-Xia LIU Liang-Qing ZHANG Hua TANG Yi-Xin HU Li FAN Qi HUA | 2019 | Journal of Geriatric Cardiology2019，16，8： | 8 |
| 9 | Review of computer-generated hologram algorithms for color dynamic holographic three-dimensional display显示文摘Holographic three-dimensional display is an important display technique because it can provide all depth information of a real or virtual scene without any special eyewear.In recent years,with the development of computer and optoelectronic technology,computer-generated holograms have attracted extensive attention and developed as the most promising method to realize holographic display.However,some bottlenecks still restrict the development of computer-generated holograms,such as heavy computation burden,low image quality,and the complicated system of color holographic display.To overcome these problems,numerous algorithms have been investigated with the aim of color dynamic holographic three-dimensional display.In this review,we will explain the essence of various computer-generated hologram algorithms and provide some insights for future research. | Dapu Pi Juan Liu Yongtian Wang | 2022 | Light(Science & Applications)2022，11，9： | 8 |
| 10 | The RNA-binding protein QKI5 regulates primary miR-124-1 processing via a distal RNA motif during erythropoiesis显示文摘 | Fang Wang Wei Song Hongmei Zhao Yanni Ma Yuxia Li Di Zhai Jingnan Pi Yanmin Si Jiayue Xu Lei Dong Rui Su Mengmeng Zhang Yong Zhu Xiaoxia Ren Fei Miao Wenjie Liu Feng Li Junwu Zhang Aibin He Ge Shan Jingyi Hui Linfang Wang Jia Yu | 2017 | Cell Research2017，27，3： | 7 |
| 11 | Urinary metabonomics study of Wu-tou-tang and its co-decoction with Pinelliae Rhizoma in adjuvant-induced arthritis rats显示文摘Wu-tou-tang was applied to treat rheumatoid arthritis,rheumatic arthritis,and joint pain for thousands of years.Aconiti Radix Cocta is the primary component of Wu-tou-tang,and Aconiti Radix and Pinelliae Rhizoma is one of the famous combination taboos in traditional Chinese medicine.A urinary metabonomics method based on the ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry(UPLC-Q-TOF-MS) had been established to quantify the changes of the endogenous metabolites in the urine of adjuvant-induced arthritis rats treated by Wutou-tang and Wu-tou-tang and Pinelliae Rhizoma(WP) co-decoctions.There was a clear separation between Wu-tou-tang and WP co-decoction treated groups in the PCA model.16 potential biomarkers had been identified which correlated with how Pinelliae Rhizoma influenced the therapeutic effect made by Wu-tou-tang.Results showed that it could reduce the therapeutic effects or make some side effects when Pinelliae Rhizoma is added in Wu-tou-tang.This is the first time to use metabonomics to investigate the reason of combination taboo. | Yao Qi Zi-Feng Pi Shu Liu Feng-Rui Song Ying Xu Na Lin Zhi-Qiang Liu | 2015 | Chinese Chemical Letters2015，26，3： | 6 |
| 12 | Ensemble kernel method:SVM classification based on game theory显示文摘With the development of the support vector machine(SVM),the kernel function has become one of the cores of the research on SVM.To a large extent,the kernel function determines the generalization ability of the classifier,but there is still no general theory to guide the choice and structure of the kernel function.An ensemble kernel function model based on the game theory is proposed,which is used for the SVM classification algorithm.The model can effectively integrate the advantages of the local kernel and the global kernel to get a better classification result,and can provide a feasible way for structuring the kernel function.By making experiments on some standard datasets,it is verified that the new method can significantly improve the accuracy of classification. | Yufei Liu Dechang Pi Qiyou Cheng | 2016 | Journal of Systems Engineering and Electronics2016，27，1： | 6 |
| 13 | Studies of the intestinal absorption of the alkaloids in the Wu-tou decoction combined with different incompatible medicinal herbs in a Caco-2 cell culture system using UPLC-MS/MS显示文摘In this study,seven alkaloids were detected in Wu-tou decoction using ultra performance liquid chromatography coupled with tandem mass spectrometry(UPLC-MS').The aim of this study was to investigate the effect of Fritillariae Cirrhosae Bulbus,Fritillariae Thunbergii Bulbils,Pinelliae Rhizoma in different ratios with Wu-tou decoction(2:1,1:1,1:2) by measuring the therapeutic effects in Wu-tou decoction of main seven alkaloids including benzoylaconitine(BA),benzoylmesaconitine(BM),benzoylhypaconitine(BH),hypaconitine(HA),fuziline(FU),niaolin(NE) and deoxyaconitine(DA).The permeability of aconitum alkaloids extract through a Caco-2 cell monolayer was analyzed in the absence and presence of Fritillariae Cirrhosae Bulbus,Fritillariae Thunbergii Bulbus,and Pinelliae Rhizoma,respectively.The results showed that Pinelliae Rhizoma could reduce the absorption of the alkaloids and increase the excretion of the alkaloids,which would attenuate the therapeutic effects of Wu-tou decoction.Therefore.Pinelliae Rhizoma is an incompatible herb of Wu-tou decoction because of the inhibition of the absorption of alkaloids in the intestine.And that Fritillariae Cirrhosae Bulbus and Fritillariae Thunbergii Bulbus showed the effects to improve the permeability of the alkaloids in Wu-tou decoction.These effects of these two herbs were similar,but the former was stronger than the latter,which most likely is clue to the fact that the compositions of these two traditional Chinese medicines are similar.The in vitro data suggests that the compounds such as fritillary presented in alkaloids in the formula maybe improve the therapeutic function caused by the increased bioavailability of alkaloids in intestine. | Hong Kan Wen-Yue Jiang Ru Ding Zhong-Ying Liu Zi-Feng Pi Zhi-Qiang Liu | 2015 | Chinese Chemical Letters2015，26，5： | 5 |
| 14 | Evaluation of emergency tourniquets for prehospital use in China显示文摘客观巨大的出血在武装冲突期间是威胁生活的。止血带是过去常减少在损伤的严重流血的重要医药设备。这研究的目的是以经验为主地评估在中国使用的当前的止血带并且在选择适当止血带提供信息给紧急情况护士。方法五条止血带由 20 个健康参加者是自我适用的。对止血带地点远侧的血流动用脉管的 Doppler 超声被估计。应用程序时间,疼痛,麻木,和另外的参数被评估。结果膀胱止血带和吊起止血带有效地堵塞了有成功的动脉的血流动在两个比 75% 高评价上面、更低的极限。货物带最快适用,拿(7. | GUO Jun-yan LIU Yu MA Yan-lan PI Hong-ying WANG Jian-rong | 2011 | Chinese Journal of Traumatology2011，14，3： | 5 |
| 15 | Improved performance of aluminum pigments encapsulated in hybrid inorganic-organic films显示文摘An organic silane acrylate resin(PMBK) was synthesized by free-radical solution polymerization using methyl methacrylate,butyl acrylate and(3-methacryloxypropyl)trimethoxysilane as monomers.Aluminum(Al) particles were then encapsulated in inorganic-organic hybrid films that were prepared by hydrolysis and condensation of PMBK and tetraethyl orthosilicate(TEOS) on the surface of Al pigments.Characterization results showed that PMBK and TEOS could simultaneously hydrolyze and condense with hydroxyl groups on the surface of the Al particles to form composite Al particles coated with inorganic-organic hybrid films.Compared with raw Al particles,the corrosion resistance and adhesive properties of paint films containing the composite Al particles were improved greatly,while the glossiness of the paint films decreased slightly,from 48.6° to 47.0°.In alkaline media(pH 11),the volume of evolved H_2 of composite Al particles was only 3.5 mL,whereas that of raw Al was 83.5 mL.The glossiness of paint films containing composite Al particles decreased by 1.66%after immersion in alkaline media for24 h,whereas that of raw Al decreased by 14.82%.Peel-off tests of the paint films showed that the composite particles moved slightly away from the paint films.In contrast,the raw Al particles were seriously desquamated,suggesting encapsulation of hybrid films can greatly improve the adhesive properties of Al particles in paint films. | Pihui Pi Chao Liu Xiufang Wen Lianfu Zheng Shouping Xu Jiang Cheng | 2015 | Particuology2015，13，2： | 5 |
| 16 | Pharmacokinetics of aminophylline delivered to the small intestine and colon using remote controlled capsules显示文摘背景获专利的 remote controlled 囊(RCC ) 最近被开发了在允许对的评价的人的内脏提供 noninvasive 药交货给选择地点地区性胃肠(官方补给) 在正常生理的环境下面的药吸收。这研究的目的是用 RCC 和监视的一个磁性的标记( MMM )在官方补给的道在这药的地点特定的交货以后调查 aminophylline 吸收的率和程度 technique.Methods 这研究在 12 个健康男题目被进行,在里面一三处理,使随机化,有7天的冲刷的转线路举止。合格题目通过一个口头的政府收到了 150 mg aminophylline 剂量,或经由 remote controlled 囊,送到小肠或上升冒号。MMM 被采用监视 RCC 的官方补给的运输,并且无线电频率信号被用来在目标地点激活囊。血样品在常规间隔被获得直到 24 小时柱子剂量 / 激活。血浆 theophylline 集中被一个 TDx 系统分析器测量。有 aminophylline 的口头的 dosing 线路的 PK 侧面的比较在交货以后被执行到小肠和 colon.Results RCC 很好在志愿者被容忍。小肠和上升冒号的吝啬的囊激活时间是 2.07 个小时和 6.08 小时柱子剂量。 Aminophylline 与胃相比从小肠有类似的吸收侧面,与在曲线( AUC_t )下面的一个区域92%的比率对胃,而是从上升冒号的更低的吸收侧面,与47.2%的 AUC_t 比率对 stomach.Conclusions RCC 和 MMM 技术提议的业主在 noninvasive 下面在人在药的肠的吸收上获得数据的机会调节。Aminophylline 很快并且高效地从小肠被吸收。当尽管有效吸收从上升冒号被观察,结肠的吸收被差的水条件限制时。这为修改版本的明确的表达以及其他的剂量形式的合理开发提供一个机会。 | LIU Hong-ying PI Xi-tian ZHENG Xiao-lin HOU Wen-sheng CUI Jian-guo | 2010 | Chinese Medical Journal2010，，3： | 4 |
| 17 | Moisture sorption and diffusion determination of Chinese herbal granules:Moisture-resistant effects of fluidized bed granulation with dextrin显示文摘Objective: To investigate the effects of fluidized bed granulation with dextrin on moisture sorption and diffusion of Zexie Decoction granules.Methods: The particle characterization was studied by the particle size, scanning electron microscopy(SEM), differential scanning calorimetry(DSC), and Fourier transform infrared(FTIR). The moisture sorption isotherm, equilibrium moisture content(EMC), and moisture diffusion coefficients were determined by using the saturated salt solution method.Results: The particle size increased from 6.04 μm(powder) to 1201.47 μm(granule). The glass transition temperature of dextrin, Zexie Decoction powder, and granule was 107.13 °C, 94.82 °C, and 126.25 °C. As the increase of temperature, the initial rate of moisture sorption become higher. Furthermore, the initial rate of moisture sorption of Zexie Decoction granules was lower than those of powders and dextrin. The EMC and moisture diffusion coefficients were reduced significantly after granulation(P < 0.01). Critical relative humidity and diffusion activation energy of granules were higher than powders.Conclusion: Results suggested that fluidized bed granulation with dextrin could reduce the hygroscopicity of the Zexie Decoction extract powders and inhibited moisture diffusion, which is mainly related to the microstructure reorganization by fluidized bed granulation and anti-plasticizing effects of dextrin. | Peng-jun Han Zhi-feng Xue Li-na Zhang Bing Zhang Dong-li Qi Jia-xin Pi Nan Li Pan Guo Zhi-dong Liu | 2018 | Chinese Herbal Medicines2018，10，3： | 4 |
| 18 | A Preliminary Study of the Noninvasive Remote Control System for Rat Bio-Robot显示文摘A system is described here that can noninvasively control the navigation of freely behaving rat via ultrasonic,epidermaland LED photic stimulators on the back.The system receives commands from a remote host computer to deliver specifiedelectrical stimulations to the hearing,pain and visual senses of the rat respectively.The results demonstrate that the three stimuliwork in groups for the rat navigation.We can control the rat to proceed and make right and left turns with great efficiency.Thisexperiment verified that the rat was able to reach a setting destination in the way of cable with the help of a person through theappropriate coordination of the three stimulators.The telemetry video camera mounted on the head of the rat also achieveddistant image acquisition and helped to adjust its navigation path over a distance of 300 m.In a word,the non-invasive motioncontrol navigation system is a good,stable and reliable bio-robot. | Xitian Pi~(1,2),Shuangshuang Li~1,Lin Xu~1,Hongying Liu~1,Shenshan Zhou~1,Kang Wei~1,Zhenyu Wang~1,Ziru Jia,Xiaolin Zheng~(1,2),Zhiyu Wen~2 1.Bioengineering College,Chongqing University,Chongqing 400030,P.R.China 2.Key Laboratories for National Defense Science and Technology of Innovative Micro-Nano Devices and System Technology,Chongqing University,Chongqing 400030,P.R.China | 2010 | Journal of Bionic Engineering2010，7，4： | 4 |
| 19 | Enhanced remediation of Cr(Ⅵ)-contaminated groundwater by coupling electrokinetics with ZVI/Fe_(3)O_(4)/AC-based permeable reactive barrier显示文摘Although widely used in permeation reaction barrier(PRB)for strengthening the removal of various heavy metals,zero-valent iron(ZVI)is limited by various inherent drawbacks,such as easy passivation and poor electron transfer.As a solution,a synergistic system with PRB and electrokinetics(PRB-EK)was established and applied for the efficient removal of Cr(Ⅵ)-contaminated groundwater.As the filling material of PRB,ZVI/Fe_(3)O_(4)/activated carbon(ZVI/Fe_(3)O_(4)/AC)composites were synthesized by ball milling and thermal treatment.A series of continuous flow column experiments and batch tests was conducted to evaluate the removal efficiency of Cr(Ⅵ).Results showed that the removal efficiency of Cr(Ⅵ)remained above 93%even when the bed volume(BV)reached 2000 under the operational parameters(iron/AC mass ratio,2:1;current,5 m A).The mechanism of Cr(Ⅵ)removal by the PRB-EK system was revealed through field emission scanning electron microscopy images,X-ray diffraction,X-ray photoelectron spectroscopy,Fe^(2+) concentration,and redox potential(E h)values.The key in Cr(Ⅵ)reduction was the Fe^(2+)/Fe^(3+) cycle driven by the surface microelectrolysis of the composites.The application of an externally supplied weak direct current maintained the redox process by enhancing the electron transfer capability of the system,thereby prolonging the column lifetime.Cr(Ⅵ)chemical speciation was determined through sequential extraction,verifying the stability and safety of the system.These findings provide a scientific basis for PRB design and the in-situ remediation of Cr(Ⅵ)-contaminated groundwater. | Ruolin Cao Shiqing Liu Xinyu Yang Chunfeng Wang Yanbin Wang Wanfeng Wang Yunqing Pi | 2022 | Journal of Environmental Sciences2022，34，2： | 4 |
| 20 | Mechanism of Incompatible Herb Pairs, Panax ginseng and Veratrum nigrum L,: Material Basis and Metabolic Profiles of Ginsenosides in Rat Intestinal Bacteria显示文摘在繁体中文药理论,人参属人参和 Veratrum nigrum L。是重要不兼容的植物对。在老鼠的新陈代谢上的主要部件和影响的内容变化上的研究肠的细菌是有用的理解这的不兼容的机制植物对。在这研究,人参皂甙和他们的 metaboltic 的内容变化在 P 的摘录介绍。P 的人参和相容性。有 V 的人参。nigrum L。(G-V ) 用 electrospray 电离团 spectrometry (ESIMS ) 和 UPLCMS n , 分别地。大多数人参皂甙的相对内容在 G-V 的摘录被减少。而且,人参皂甙 Rb 1, Rb 2, Rc 和 Rd 能在老鼠被使产生代射变化到 Rd, F2 和 C-K 肠的细菌。在在 10:5, 10:7 和 10:10 和人参皂甙 Rb 1, Rb 2 的新陈代谢的率的比率的 G-V 摘录的 Rb 1, Rb 2 和 Rc 和到 Rd 的 Rc 的新陈代谢的速度,到在所有相容性摘录的 F2 的 Rd 在 P 是比那低的。人参摘录。在结论,这研究说明了机制由相对内容的比较和在 P 的相容性以后的人参皂甙的新陈代谢的侧面减少效果。人参和 V。nigrum L。 | Xiudong Yang Xue Li Ying Xu Zifeng Pi Na Lin Zhiqiang Liu Fengrui Song | 2015 | Chinese Journal of Chemistry2015，33，9： | 3 |
您所在的机构暂未开通此部分的功能，请联系管理员