|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Gastric cancer risk in relation to tobacco use and alcohol drinking in Kerala, India-Karunagappally cohort study显示文摘AIM: To assess the risk of gastric cancer(GC) in relation to tobacco use and alcohol drinking in the Karunagappally cohort in Kerala, South India.METHODS: This study examined the association of tobacco use and alcohol drinking with GC incidence among 65553 men aged 30-84 in the Karunagappally cohort. During the period from 1990-2009, 116 GC cases in the cohort were identified as incident cancers. These cases were identified from the populationbased cancer registry. Information regarding risk factors such as socioeconomic factors and tobacco and alcohol habits of cohort members were collected from the database of the baseline survey conducted during 1990-1997. The relative risks(RRs) and the corresponding 95% confidence intervals(95%CIs) fortobacco use were obtained from Poisson regression analysis of grouped survival data, considering age, follow-up period, occupation and education.RESULTS: Bidi smoking was associated with GC risk(P = 0.042). The RR comparing current versus never smokers was 1.6(95%CI: 1.0-2.5). GC risk was associated with the number of bidis smoked daily(P = 0.012) and with the duration of bidi smoking(P = 0.036). Those who started bidi smoking at younger ages were at an elevated GC risk; the RRs for those starting bidi smoking under the age of 18 and ages 18-22 were 2.0(95%CI: 1.0-3.9) and 1.8(95%CI: 1.1-2.9), respectively, when their risks were compared with lifetime non-smokers of bidis. Bidi smoking increased the risk of GC among never cigarette smokers more evidently(RR = 2.2; 95%CI: 1.3-4.0). GC risk increased with the cumulative amount of bidi smoking, which was calculated as the number of bidis smoked per day x years of smoking(bidi-year; P = 0.017). Cigarette smoking, tobacco chewing or alcohol drinking was not significantly associated with GC risk. CONCLUSION: Among a male cohort in South India, gastric cancer risk increased with the number and duration of bidi smoking. | Padmavathy Amma Jayalekshmi Soroush Hassani Athira Nandakumar Chihaya Koriyama Paul Sebastian Suminori Akiba | 2015 | World Journal of Gastroenterology2015，21，44： | 19 |
| 2 | Use of models in large-area forest surveys: comparing model-assisted, model-based and hybrid estimation显示文摘This paper focuses on the use of models for increasing the precision of estimators in large-area forest surveys.It is motivated by the increasing availability of remotely sensed data,which facilitates the development of models predicting the variables of interest in forest surveys.We present,review and compare three different estimation frameworks where models play a core role:model-assisted,model-based,and hybrid estimation.The first two are well known,whereas the third has only recently been introduced in forest surveys.Hybrid inference mixes designbased and model-based inference,since it relies on a probability sample of auxiliary data and a model predicting the target variable from the auxiliary data.We review studies on large-area forest surveys based on model-assisted,modelbased,and hybrid estimation,and discuss advantages and disadvantages of the approaches.We conclude that no general recommendations can be made about whether model-assisted,model-based,or hybrid estimation should be preferred.The choice depends on the objective of the survey and the possibilities to acquire appropriate field and remotely sensed data.We also conclude that modelling approaches can only be successfully applied for estimating target variables such as growing stock volume or biomass,which are adequately related to commonly available remotely sensed data,and thus purely field based surveys remain important for several important forest parameters. | Goran Stahl Svetlana Saarela Sebastian Schnell Soren Holm Johannes Breidenbach Sean P. Healey Paul L. Patterson Steen Magnussen Erik Naesset Ronald E. McRoberts Timothy G. Gregoire | 2016 | Forest Ecosystems2016，3，2： | 7 |
| 3 | Low kilovoltage cardiac dual-source CT: attenuation, noise, and radiation dose显示文摘 | Sebastian Leschka Paul Stolzmann Florian T. Schmid Hans Scheffel Bjoern Stinn Borut Marincek Hatem Alkadhi Simon Wildermuth | 2008 | European Radiology2008，，9： | 3 |
| 4 | Towards a standard diet-induced and biopsy-confirmed mouse model of non-alcoholic steatohepatitis: Impact of dietary fat source显示文摘BACKGROUND The trans-fat containing AMLN(amylin liver non-alcoholic steatohepatitis,NASH)diet has been extensively validated in C57BL/6J mice with or without the Lep^ob/Lep^ob(ob/ob)mutation in the leptin gene for reliably inducing metabolic and liver histopathological changes recapitulating hallmarks of NASH.Due to a recent ban on trans-fats as food additive,there is a marked need for developing a new diet capable of promoting a compatible level of disease in ob/ob and C57BL/6J mice.AIM To develop a biopsy-confirmed mouse model of NASH based on an obesogenic diet with trans-fat substituted by saturated fat.METHODS Male ob/ob mice were fed AMLN diet or a modified AMLN diet with trans-fat(Primex shortening)substituted by equivalent amounts of palm oil[Gubra amylin NASH,(GAN)diet]for 8,12 and 16 wk.C57BL/6J mice were fed the same diets for 28 wk.AMLN and GAN diets had similar caloric content(40%fat kcal),fructose(22%)and cholesterol(2%)level.RESULTS The GAN diet was more obesogenic compared to the AMLN diet and impaired glucose tolerance.Biopsy-confirmed steatosis,lobular inflammation,hepatocyte ballooning,fibrotic liver lesions and hepatic transcriptome changes were similar in ob/ob mice fed the GAN or AMLN diet.C57BL/6J mice developed a mild to moderate fibrotic NASH phenotype when fed the same diets.CONCLUSION Substitution of Primex with palm oil promotes a similar phenotype of biopsyconfirmed NASH in ob/ob and C57BL/6J mice,making GAN diet-induced obese mouse models suitable for characterizing novel NASH treatments. | Michelle L Boland Denise Oro Kirstine S T■lb■l Sebastian T Thrane Jens Christian Nielsen Taylor S Cohen David E Tabor Fiona Fernandes Andrey Tovchigrechko Sanne S Veidal Paul Warrener Bret R Sellman Jacob Jelsing Michael Feigh Niels Vrang James L Trevaskis Henrik H Hansen | 2019 | World Journal of Gastroenterology2019，25，33： | 3 |
| 5 | Diagnostic accuracy of high-pitch dual-source CT for the assessment of coronary stenoses: first experience显示文摘 | Sebastian Leschka Paul Stolzmann Lotus Desbiolles Stephan Baumueller Robert Goetti Thomas Schertler Hans Scheffel Andre Plass Volkmar Falk Gudrun Feuchtner Borut Marincek Hatem Alkadhi | 2009 | European Radiology2009，，12： | 2 |
| 6 | Genetic Determinants of Dabigatran Plasma Levels and Their Relation to Bleeding显示文摘 | Guillaume Paré Niclas Eriksson Thorsten Lehr Stuart Connolly John Eikelboom Michael D. Ezekowitz Tomas Axelsson Sebastian Haertter Jonas Oldgren Paul Reilly Agneta Siegbahn Ann-Christine Syvanen Claes Wadelius Mia Wadelius Heike Zimdahl-Gelling Salim Yusu | 2013 | Circulation2013，，13： | 2 |
| 7 | 拉科酰胺在癫痫持续状态中的应用--针对现有证据的系统评价显示文摘拉科酰胺(Lacosamide,LCM)的静脉制剂具有良好的耐受性和安全性,促使其在癫痫持续状态(Status Epilepticus,SE)中得到应用。本项系统评价的目的是确定和评估LCM在SE中的使用情况。在电子数据库中用联合检索方式对2008年—2016年10月的文献进行了系统检索,并使用标准化的评估表格从各项研究中将有关研究设计、方法框架、数据源、有效性和LCM引起的不良反应的信息进行提取并系统地报告。研究共评估了522次SE发作,其中包括486例成人和36例儿童及青少年发作,女性占51.7%。LCM的总体效力为57%。LCM对非惊厥性(57%,82/145)和全面痉挛性(61%,30/49,P=0.68)SE的效力相似,但对局灶运动性SE的总体有效率更高(92%,34/39,P<0.001)。而LCM在用药次序靠后时其疗效从100%下降到20%。治疗期间的主要不良反应是眩晕,视力异常,复视和共济失调。总体而言,LCM具有良好的耐受性,并且没有具临床意义的药物相互作用。现有数据表明LCM在SE中的使用是有前景的,有效率为57%。LCM的优势在于没有潜在的药物相互作用,并且在紧急情况需迅速增加剂量时可静脉使用。 | Adam Strzelczyk Johann Philipp Zollner Laurent M Willems 肖英凤 童馨 慕洁 Julie Jost Esther Paule Susanne Schubert-Bast Felix Rosenow Sebastian Bauer | 2018 | 癫痫杂志2018，4，5： | 2 |
| 8 | Effect of operating condition and input variation on the partition of metals in a municipal solid waste incinerator显示文摘 | Leo S Morf Paul H Brunner Sebastian Spaun | 2000 | Waste Manage Res2000，18，1： | 1 |
| 9 | Effect of operating conditions and input variations on the partitioning of metals in a municipal solid waste incinerator 显示文摘 | Morf Leo S Brunner Paul H Spaun Sebastian | 2000 | Waste Management and Research2000，18，1： | 1 |
| 10 | Irritable bowel syndrome and organic diseases: A comparative analysis of esophageal motility显示文摘AIM:To assess the esophageal motility in patients with irritable bowel syndrome(IBS)and to compare those with patients with autoimmune disorders.METHODS:15 patients with IBS,22 with systemic lupus erythematosus(SLE)and 19 with systemic sclerosis(SSc)were prospectively selected from a total of 115patients at a single university centre and esophageal motility was analysed using standard manometry(Mui Scientific PIP-4-8SS).All patients underwent esophagogastro-duodenoscopy before entering the study so that only patients with normal endoscopic findings were included in the current study.All patients underwent a complete physical,blood biochemistry and urinary examination.The grade of dysphagia was determined for each patient in accordance to the intensity and frequency of the presented esophageal symptoms.Furthermore,disease activity scores(SLEDAI and modified Rodnan score)were obtained for patients with autoimmune diseases.Outcome parameter:A correlation coefficient was calculated between amplitudes,velocity and duration of the peristaltic waves throughout esophagus and patients’dysphagia for all three groups.RESULTS:There was no statistical difference in the standard blood biochemistry and urinary analysis in all three groups.Patients with IBS showed similar pathologic dysphagia scores compared to patients with SLE and SSc.The mean value of dysphagia score was in IBS group 7.3,in SLE group 6.73 and in SSc group7.56 with a P-value>0.05.However,the manometric patterns were different.IBS patients showed during esophageal manometry peristaltic amplitudes at the proximal part of esophagus greater than 60 mmHg in46%of the patients,which was significant higher in comparison to the SLE(11.8%)and SSc-Group(0%,P=0.003).Furthermore,IBS patients showed lower mean resting pressure of the distal esophagus sphincter(Lower esophageal sphincter,22 mmHg)when compared with SLE(28 mmHg,P=0.037)and SSc(26 mmHg,P=0.052).23.5%of patients with SLE showed amplitudes greater as 160 mmHg in the distal esophagus(IBS and SSc:0%)whereas 29.4%amplitudes greater as 100 mmHg in the middle one(IBS:16.7%,SSc:5.9%respectively,P=0.006).Patients with SSc demonstrated,as expected,in almost half of the cases reduced peristalsis or even aperistalsis in the lower two thirds of the esophagus.SSc patients demonstrated a negative correlation coefficient between dysphagia score,amplitude and velocity of peristaltic activity at middle and lower esophagus[r=-0.6,P | Thomas Thomaidis Martin Goetz Sebastian Paul Gregor Arthur Hoffman Elias Kouroumalis Markus Moehler Peter Robert Galle Andreas Schwarting Ralf Kiesslich | 2013 | World Journal of Gastroenterology2013，19，38： | 1 |
| 11 | Dual- Source CT in step-and-shoot mode: noninvasive coronary angi ography with low radiation dose 显示文摘 | Paul Stozmann Sebastian Leschka Hans Scheffel | 2008 | Radiology2008，249，： | 1 |
| 12 | Dual-source computed tomography in patients with acute chest pain: feasibility and image quality显示文摘 | Thomas Schertler Hans Scheffel Thomas Frauenfelder Lotus Desbiolles Sebastian Leschka Paul Stolzmann Burkhardt Seifert Thomas G. Flohr Borut Marincek Hatem Alkadhi | 2007 | European Radiology2007，，12： | 1 |
| 13 | High-pitch dual-source CT coronary angiography: systolic data acquisition at high heart rates显示文摘 | Robert Goetti Gudrun Feuchtner Paul Stolzmann Lotus Desbiolles Michael Alexander Fischer Christoph Karlo Stephan Baumueller Hans Scheffel Hatem Alkadhi Sebastian Leschka | 2010 | European Radiology2010，，11： | 1 |
| 14 | Diagnostic accuracy of high-pitch dual-source CT for the assessment of coronary stenoses: first experience显示文摘 | Sebastian Leschka Paul Stolzmann Lotus Desbiolles Stephan Baumueller Robert Goetti Thomas Schertler Hans Scheffel Andre Plass Volkmar Falk Gudrun Feuchtner Borut Marincek Hatem Alkadhi | 2009 | European Radiology2009，，12： | 1 |
| 15 | Single‐institution experience with ipilimumab in advanced melanoma patients in the compassionate use setting显示文摘 | Geoffrey Y.Ku JiandaYuan David B.Page Sebastian E. A.Schroeder Katherine S.Panageas Richard D.Carvajal Paul B.Chapman Gary K.Schwartz James P.Allison Jedd D.Wolchok | 2010 | Cancer2010，，7： | 1 |
| 16 | Volatility dependence and contagion in emerging equity markets 显示文摘 | Sebastian Edwards Paul Susmel | 2001 | Journal of Devel- opment Economics2001，，66： | 1 |
| 17 | Dual-Energy Contrast-Enhanced Computed Tomography for the Detection of Urinary Stone Disease显示文摘 | Hans Scheffel Paul Stolzmann Thomas Frauenfelder Thomas Schertler Lotus Desbiolles Sebastian Leschka Borut Marincek Hatem Alkadhi | 2007 | Investigative Radiology2007，，12： | 1 |
| 18 | REAL-TIME COMPLEX EVENT RECOGNITION AND REASONING–A LOGIC PROGRAMMING APPROACH显示文摘 | Darko Anicic Sebastian Rudolph Paul Fodor Nenad Stojanovic | 2012 | Applied Artificial Intelligence . 2012 (1-2)2012，，： | 1 |
| 19 | Sea‐level and ocean‐current control on carbonate‐platform growth, M aldives, I ndian O cean显示文摘 | Christian Betzler J?rn Fürstenau Thomas Lüdmann Christian Hübscher Sebastian Lindhorst Andreas Paul John J. G. Reijmer André W. Droxler | 2012 | Basin Res2012，，： | 1 |
| 20 | Oral bioavailability of dabigatran etexilate ( P radaxa<sup>?</sup>) after co‐medication with verapamil in healthy subjects显示文摘 | Sebastian H?rtter Regina Sennewald Gerhard Nehmiz Paul Reilly | 2013 | Br J Clin Pharmacol2013，，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员