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281篇 您的检索式:作者名="PATRICIA D"
    题名 作者 年代 出处 被引量
1Movat五色套染法的改进及应用显示文摘李莉 翟同钧 陈融 胡维诚 Patricia D Polinsky 2002临床与实验病理学杂志2002,18,6:20
2燃煤飞灰吸附脱汞能力的实验研究显示文摘运用煤岩学分类相关理论对燃煤飞灰岩相组成进行了系统定量分析,并采用固定床汞吸附反应系统对不同电厂飞灰吸附汞的能力进行了详细研究,结果表明:不同的飞灰对汞均有一定的吸附能力,其中以烟煤飞灰CTSR和CTL的富碳组分对汞的吸附能力最强,其吸附能力分别为10.3和9.36μg/g,与商业活性炭捕获能力相当;飞灰中汞的含量与其含炭量和比表面积并无明显的相关性.揭示了飞灰颗粒岩相组成,分析了飞灰脱汞能力的影响因素.不同飞灰碳颗粒类型脱汞性能差异明显,各向异性碳颗粒尤其是多孔网状结构碳含量是决定飞灰脱汞能力的主要因素.赵永椿 张军营 刘晶 DíAZ-SOMOANO Mercedes ABAD-VALLE Patricia MARTíNEZ-TARAZONA M Rosa 郑楚光 2010中国科学:技术科学2010,40,4:15
3Experimental study on fly ash capture mercury in flue gas显示文摘Systematic experiments were conducted on a fixed-bed reactor to investigate the interaction between fly ash and mercury,the results implied that fly ash can capture mercury effectively.Among different fly ashes,the unburned carbon in the FA2 and FA3 fly ashes has the highest mercury capture capacity,up to 10.3 and 9.36 μg/g,respectively,which is close to that of commercial activated carbon.There is no obvious relationship between mercury content and carbon content or BET surface area of fly ash.Petrography classification standard was applied to distinguish fly ash carbon particles.Carbon content is not the only variable that controls mercury capture on fly ash,there are likely significant differences in the mercury capture capacities of the various carbon forms.Mercury capture capacity mainly depends on the content of anisotropy carbon particles with porous network structure.Mercedes DíAZ-SOMOANO Patricia ABAD-VALLE M.Rosa MARTíNEZ-TARAZONA 2010Science China(Technological Sciences)2010,53,4:12
4对原则导向制准则及规则导向制准则的制定方法之评价显示文摘引言 美国财务会计准则委员会(FASB)在其汇编和简化准则的新计划中表明:其意图在于评价是否可能以原则导向制准则来取代详细的、以规则为导向并包含例外情况及可供选择条例的准则.①为此,FASB的委员和职员要求美国会计学会的财务会计准则委员会(下文中简称为'委员会')就原则导向制准则做出评论,并将两条准则改写为原则导向制准则.Laureen A Maines Eli Bartov Patricia Fairfield D Eric Hirst 罗妍 2004经济资料译丛2004,,2:6
5从附睾到卵子:CRISP蛋白在哺乳动物受精过程中的作用显示文摘哺乳动物的受精过程涉及精卵结合的很多步骤,是一个非常复杂的过程,其分了机制亟待阐明。此篇综述主要论述了CRISP(富含半胱氨酸的分泌蛋白)作为模型分子在哺乳动物受精过程中的价值。大量的体外实验和基因敲出模型研究显示,附睾内的CRISP1以两种不同的亲和力结合于精子表面,参与精子获能、精子-透明带结合、精卵融合的调控。这些研究成果可以延伸至人类。我们住研究中发现,人类具有与啮齿类同源的CRISP(hCRISP1),同样参与受精过样。CRISP家族的其他成员(睾丸内CRISP2、附挈内CRISP3—4、射精时的CRISP3)也参与了精卵结合的过程,提示同源分子间的相互协同有助于受精的成功。另外,我们的研究显示,CRISP蛋白伴随精子穿越男性及女性生殖管道的全过程。我们推测CRISP不仅参与了受精过程,而且可能成为不育和避孕研究的新靶点。Vanina G Da Ros Mariana Weigel Munoz Maria A Battistone Nicolas G Brukman Guillermo Carvajal Ludmila Curci Matlas D Gomez-Elias Debora J Cohen Patricia S Cuasnicu 2015Asian Journal of Andrology2015,17,5:5
6Effect of electrical stimulation of the lower esophageal sphincter in gastroesophageal reflux disease patients refractory to proton pump inhibitors显示文摘AIM: To evaluate the efficacy of lower esophageal sphincter(LES)-electrical stimulation therapy(EST) in a subgroup of patients that reported only partial response to proton pump inhibitors(PPIs) therapy, compared to a group of patient with complete response.METHODS: Bipolar stitch electrodes were laparoscopically placed in the LES and connected to an implantable pulse generator(EndoS tim BV, the Hague, the Netherlands), placed subcutaneously in the anterior abdominal wall. Stimulation at 20 Hz, 215 μsec, 3-8 m Amp in 30 min sessions was delivered starting on day 1 post-implant. Patients were evaluated using gastroesophageal reflux disease(GERD)-HRQL, symptom diaries; esophageal p H and esophageal manometry before and up to 24 mo after therapy and results were compared between partial and complete responders.RESULTS: Twenty-three patients with GERD on LESEST were enrolled and received continuous per-protocol stimulation through 12 mo and 21 patients completed 24 mo of therapy. Of the 23 patients, 16(8 male, mean age 52.1 ± 12 years) had incomplete response to PPIs prior to LES-EST, while 7 patients(5 male, mean age 52.7 ± 4.7) had complete response to PPIs. In the sub-group with incomplete response to PPIs, median(IQR) composite GERD-HRQL score improved significantly from 9.5(9.0-10.0) at baseline on-PPI and 24.0(20.8-26.3) at baseline off-PPI to 2.5(0.0-4.0) at 12-mo and 0.0(0.0-2.5) at 24-mo follow-up(P < 0.05 compared to on-and off-PPI at baseline). Median(IQR) % 24-h esophageal pH < 4.0 at baseline in this sub-group improved significantly from 9.8%(7.8-11.5) at baseline to 3.0%(1.9-6.3) at 12 mo(P < 0.001) and 4.6%(2.0-5.8) at 24 mo follow-up(P < 0.01). At their 24-mo follow-up, 9/11 patients in this sub-group were completely free of PPI use. These results were comparable to the sub-group that reported complete response to PPI therapy at baseline. No unanticipated implantation or stimulation-related adverse events, or any untoward sensation due to stimulation were reported in either group and LES-EST was safely tolerated by both groups. CONCLUSION: LES-EST is safe and effective in controlling symptoms and esophageal acid exposure in GERD patients with incomplete response to PPIs. These results were comparable to those observed PPI responders.Edy Soffer Leonardo Rodríguez Patricia Rodriguez Beatriz Gómez Manoel G Neto Michael D Crowell 2016World Journal of Gastrointestinal Pharmacology and Therapeutics2016,7,1:4
7Quality Improvement Guidelines for the Treatment of Lower Extremity Deep Vein Thrombosis with Use of Endovascular Thrombus Removal显示文摘Suresh Vedantham Patricia E. Thorpe John F. Cardella Clement J. Grassi Nilesh H. Patel Hector Ferral Lawrence V. Hofmann Bertrand M. Janne d’Othée Vittorio P. Antonaci Elias N. Brountzos Daniel B. Brown Louis G. Martin Alan H. Matsumoto Steven G. Meranze 2006Journal of Vascular and Interventional Radiology2006,,3:3
8Mortality Associated With Atrial Fibrillation in Patients With Myocardial Infarction: A Systematic Review and Meta-Analysis显示文摘Patricia Jabre Véronique L. Roger Mohammad H. Murad Alanna M. Chamberlain Larry Prokop Frédéric Adnet Xavier Jouven 2011Circulation2011,,15:2
9Misdiagnosis of tuberculosis and the clinical relevance of nontuberculous mycobacteria in Zambia显示文摘Objective:To determine the accuracy of TB diagnosis of TB in Zambia in the era of increasing HIV prevalence.Methods:Sputum of the clinically diagnosed TB cases was additionally subjected to liquid culture and molecular identification.This study distinguished between TB cases confirmed by positive Mycobacterium tuberculosis(M.tuberculosis) cultures and mycobacterial disease caused by non-tuberculous mycobacteria(NTM).Results:Only 49% of the 173 presumptively diagnosed TB cases was M.tuberculosis cultured,while in 13% (22) cases,a combination of M.tuberculosis and NTM was found.In 18% of the patients only NTM were cultured.In 28% ,no mycobacteria was cultivable.HIV positive status was correlated with the isolation of NTM(P<0.05).Conclusions:The diagnosis of tuberculosis based on symptoms, sputum smear and/or chest X-ray leads to significant numbers of false-positive TB cases in Zambia,most likely due to the increased prevalence of HIV.The role of NTM in tuberculosislike disease also seems relevant to the false diagnosis of TB in Zambia.Patricia CAM Buijtels Michael D Iseman Shelagh Parkinson Cas S de Graaff Henri A Verbrugh Pieter LC Petit Dick van Soolingen 2010Asian Pacific Journal of Tropical Medicine2010,3,5:2
10Non-steroidal anti-inflammatory drugs and risk of neoplastic progression in Barrett’s oesophagus: a prospective study显示文摘Thomas L Vaughan Linda M Dong Patricia L Blount Kamran Ayub Robert D Odze Carissa A Sanchez Peter S Rabinovitch Brian J Reid 2005Lancet Oncology2005,,12:2
11First characterization of endophytic Corynespora cassiicola isolates with variant cassiicolin genes recovered from rubber trees in Brazil显示文摘Corynespora cassiicola is the causal agent of Corynespora Leaf Fall(CLF)disease.CLF is one of the most important fungal diseases of rubber trees in Asia and Africa but disease outbreaks have not been reported in South America.Cassiicolin,a small cysteine-rich glycoprotein secreted by the pathogenic C.cassiicola isolate CCP,was previously identified as a potential disease effector in rubber tree.Recently,the cassiicolin-encoding gene(Cas1)was characterized and shown to be expressed in the early phase of infection.In this study,we investigated whether previously undetected strains of C.cassiicola are present in South American rubber plantations by examining the fungal endophyte population found in asymptomatic rubber tree leaves.Four isolates were identified as C.cassiicola.Genes encoding new forms of the cassiicolin precursor protein(Cas3 and Cas4)were identified from these isolates.Three of four isolates were able to induce symptoms on the cultivar they were isolated from in a detached leaf assay,with different kinetics and intensities.One isolate had the same pathogenicity profile as the pathogenic isolate CCP;the other two isolates developed symptoms late during the course of infection,suggesting saprotrophic capabilities.However,no Cas3 or Cas4 transcripts could be detected upon inoculation with the endophytic isolates,whereas the reference gene Cas1 was expressed upon inoculation with the CCP isolate.This work demonstrated that C.cassiicola is present in South America in an endophytic form and that it may evolve from an endophytic to a saprophytic or even potentially pathogenic life style.Marine Déon Ana Scomparin Aude Tixier Carlos R.R.Mattos Thierry Leroy Marc Seguin Patricia Roeckel-Drevet Valérie Pujade-Renaud 2012Fungal Diversity2012,,3:2
12Anti-hypertensive drugs in children and adolescents显示文摘Worldwide the prevalence of essential hypertension inchildren and adolescents continues to increase. Tradi-tionally providers have used 'off-label' drugs to treatpediatric hypertension, meaning that rigorous clinicaltrials of these drugs have not been specifically per-formed in pediatric patient populations. Consequentlyproviders have extrapolated dosing, safety and efficacyfrom trials in adults. This practice is sub-optimal as chil-dren demonstrate unique differences in drug metabo-lism and response. Use of unstudied or understudieddrugs increases risk of adverse events and/or can leadto sub-optimal efficacy. Recognizing these concerns,regulatory agencies have created financial incentivesfor industry to conduct pediatric clinical trials. Theseincentives, coupled with the emerging pediatric hyper-tension epidemic, have spurred over 30 clinical trialsof anti-hypertensive drugs over the past 15 years andhave resulted in labeling of 10 new drugs by the UnitedStates Food and Drug Administration for treatment ofhypertension in children and adolescents. Unfortunatelythe financial incentive structures focus on newer drugsand drug classes. Consequently there is now a relativedearth of trial data for older but sometimes commonlyprescribed pediatric antihypertensive drugs. This article reviews recent pediatric antihypertensive drug trials with a focus on trial design and endpoints, drug dosing, safety, efficacy and specific drug indications. We also review the available data and experience for some of the more commonly prescribed, but less well studied 'older' pediatric antihypertensive drugs.Patricia Y Chu Michael J Campbell Stephen G Miller Kevin D Hill 2014World Journal of Cardiology2014,6,5:2
13Quality of Life in Long - Term, Disease- Free Survivors of Breast Cancer: a Follow - up Study 显示文摘Patricia A G Katherine A D Beth L 2002J Natl Cancer Inst2002,94,1:1
14Infertility in the modem world:presentand fu--ture prospects显示文摘Patricia D Prosser 2001Fam Practice2001,18,4:1
15Perception of Diesel Engine Gear Rattle Noise显示文摘BRANDON S PATRICIA D BOLTON J S 2015SAE2015,,1:1
16LIGHT, a New Member of the TNF Superfamily, and Lymphotoxin α Are Ligands for Herpesvirus Entry Mediator显示文摘Davide N Mauri Reinhard Ebner Rebecca I Montgomery Kristine D Kochel Timothy C Cheung Guo-Liang Yu Steve Ruben Marianne Murphy Roselyn J Eisenberg Gary H Cohen Patricia G Spear Carl F Ware 1998Immunity1998,,:1
17Effect of heparin on in vitro capacitation of boar sperm显示文摘DOEA G D PATRICIA M MARCEO C 2006Biol Res2006,39,4:1
18Human a-defensins block papillornavirus infection 显示文摘Christopher B Buck Patricia M Day Cynthia D Thompson 2006PNAS2006,103,5:1
19A pilot-scale continuous-jet hydrate reactor显示文摘Phillip S Scott D M Patricia T S 0,,:1
20Quantitative conversion of phytate to inorganic phosphorus in soybean seeds expressing a bacterial phytase显示文摘 Peiyu Z Patricia C 2008Plant Physiology2008,146,2:1
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